US20080153843A1 - Substituted sulfonamide compounds - Google Patents
Substituted sulfonamide compounds Download PDFInfo
- Publication number
- US20080153843A1 US20080153843A1 US11/905,381 US90538107A US2008153843A1 US 20080153843 A1 US20080153843 A1 US 20080153843A1 US 90538107 A US90538107 A US 90538107A US 2008153843 A1 US2008153843 A1 US 2008153843A1
- Authority
- US
- United States
- Prior art keywords
- methoxy
- piperidin
- ethanone
- dimethylphenylsulfonyl
- piperazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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| US11/905,381 US20080153843A1 (en) | 2006-09-29 | 2007-09-28 | Substituted sulfonamide compounds |
| US12/862,297 US8435978B2 (en) | 2006-09-29 | 2010-08-24 | Substituted sulfonamide compounds |
| US12/862,271 US20100324009A1 (en) | 2006-09-29 | 2010-08-24 | Substituted Sulfonamide Compounds |
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| US84943806P | 2006-10-05 | 2006-10-05 | |
| US11/905,381 US20080153843A1 (en) | 2006-09-29 | 2007-09-28 | Substituted sulfonamide compounds |
Related Child Applications (2)
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| US12/862,271 Division US20100324009A1 (en) | 2006-09-29 | 2010-08-24 | Substituted Sulfonamide Compounds |
| US12/862,297 Continuation US8435978B2 (en) | 2006-09-29 | 2010-08-24 | Substituted sulfonamide compounds |
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| US11/905,381 Abandoned US20080153843A1 (en) | 2006-09-29 | 2007-09-28 | Substituted sulfonamide compounds |
| US12/862,271 Abandoned US20100324009A1 (en) | 2006-09-29 | 2010-08-24 | Substituted Sulfonamide Compounds |
| US12/862,297 Expired - Fee Related US8435978B2 (en) | 2006-09-29 | 2010-08-24 | Substituted sulfonamide compounds |
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| US12/862,297 Expired - Fee Related US8435978B2 (en) | 2006-09-29 | 2010-08-24 | Substituted sulfonamide compounds |
Country Status (24)
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| EP (2) | EP2066659B1 (sl) |
| JP (1) | JP5405303B2 (sl) |
| KR (1) | KR20090079914A (sl) |
| CN (1) | CN101553481A (sl) |
| AU (1) | AU2007304475B2 (sl) |
| BR (1) | BRPI0714764A2 (sl) |
| CA (1) | CA2664810A1 (sl) |
| CO (1) | CO6170358A2 (sl) |
| CY (1) | CY1114669T1 (sl) |
| DK (1) | DK2066659T3 (sl) |
| ES (1) | ES2436020T3 (sl) |
| HK (1) | HK1132266A1 (sl) |
| HR (1) | HRP20130958T1 (sl) |
| IL (1) | IL197814A0 (sl) |
| MX (1) | MX2009003382A (sl) |
| NO (1) | NO20091299L (sl) |
| NZ (1) | NZ575566A (sl) |
| PL (1) | PL2066659T3 (sl) |
| PT (1) | PT2066659E (sl) |
| RU (1) | RU2462464C2 (sl) |
| SI (1) | SI2066659T1 (sl) |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100113417A1 (en) * | 2008-10-29 | 2010-05-06 | Gruenenthal Gmbh | Substituted Spiroamine Compounds |
| US20100152158A1 (en) * | 2008-11-06 | 2010-06-17 | Gruenenthal Gmbh | Substituted Disulfonamide Compounds |
| WO2011125967A1 (ja) | 2010-04-05 | 2011-10-13 | 塩野義製薬株式会社 | カテコール基を有するセフェム化合物 |
| US8680159B2 (en) | 2010-09-22 | 2014-03-25 | Gruenenthal Gmbh | Bradykinin 1 receptor modulating compounds |
| WO2018212534A1 (en) | 2017-05-17 | 2018-11-22 | Legochem Biosciences, Inc. | Novel compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same |
| CN109810031A (zh) * | 2017-11-21 | 2019-05-28 | 乳源瑶族自治县东阳光生物科技有限公司 | 非罗考昔中间体的制备方法 |
| WO2023028056A1 (en) | 2021-08-24 | 2023-03-02 | Genentech, Inc. | 3-amino piperidyl sodium channel inhibitors |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007020493A1 (de) * | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Amid-Derivate |
| WO2009090055A1 (en) * | 2008-01-17 | 2009-07-23 | Grünenthal GmbH | Substituted sulfonamide derivatives |
| PE20091782A1 (es) * | 2008-04-08 | 2009-11-15 | Gruenenthal Chemie | Derivados de sulfonamida sustituida |
| TW201022267A (en) | 2008-10-23 | 2010-06-16 | Gruenenthal Gmbh | Substituierte pyrimidin-und triazin-derivate |
| TW201031665A (en) | 2009-02-04 | 2010-09-01 | Gruenenthal Gmbh | Substituted indole-compound |
| TW201030007A (en) | 2009-02-06 | 2010-08-16 | Gruenenthal Gmbh | Substituted spiro-amides as b1r modulators |
| TW201035102A (en) | 2009-03-04 | 2010-10-01 | Gruenethal Gmbh | Sulfonylated tetrahydroazolopyrazines and their use as medicinal products |
| TW201038572A (en) | 2009-03-25 | 2010-11-01 | Gruenenthal Gmbh | Substituted spiro-amide compounds |
| BRPI1010649A2 (pt) | 2009-06-08 | 2016-06-07 | Gruenenthal Gmbh | benzimidazóis, benzotiazóis e benzoxazoles substituídos. |
| AR082890A1 (es) | 2010-09-03 | 2013-01-16 | Gruenenthal Gmbh | Derivados sustituidos de tetrahidropirrolopirazina |
| CN106748627A (zh) * | 2016-11-14 | 2017-05-31 | 苏州市罗森助剂有限公司 | 一种一锅法制备3,5‑二甲基溴苯的方法 |
| CA2965062A1 (en) * | 2017-04-25 | 2018-10-25 | Nova Chemicals Corporation | Complex comprising odh unit with integrated oxygen separation module |
| CN116253667A (zh) * | 2022-12-27 | 2023-06-13 | 煤炭科学研究总院有限公司 | 一种聚集诱导发光材料及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20040171614A1 (en) * | 2002-02-06 | 2004-09-02 | Schering-Plough Corporation | Novel gamma secretase inhibitors |
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| US20080306084A1 (en) * | 2007-04-30 | 2008-12-11 | Gruenenthal Gmbh | Substituted Amide Compounds |
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- 2007-09-27 CA CA002664810A patent/CA2664810A1/en not_active Abandoned
- 2007-09-27 CN CNA2007800436108A patent/CN101553481A/zh active Pending
- 2007-09-27 NZ NZ575566A patent/NZ575566A/en not_active IP Right Cessation
- 2007-09-27 AU AU2007304475A patent/AU2007304475B2/en not_active Ceased
- 2007-09-27 RU RU2009115960/04A patent/RU2462464C2/ru not_active IP Right Cessation
- 2007-09-27 DK DK07818500.6T patent/DK2066659T3/da active
- 2007-09-27 ES ES07818500T patent/ES2436020T3/es active Active
- 2007-09-27 JP JP2009529606A patent/JP5405303B2/ja not_active Expired - Fee Related
- 2007-09-27 PT PT78185006T patent/PT2066659E/pt unknown
- 2007-09-27 EP EP07818500.6A patent/EP2066659B1/de active Active
- 2007-09-27 PL PL07818500T patent/PL2066659T3/pl unknown
- 2007-09-27 KR KR1020097008960A patent/KR20090079914A/ko not_active Application Discontinuation
- 2007-09-27 BR BRPI0714764-3A2A patent/BRPI0714764A2/pt not_active IP Right Cessation
- 2007-09-27 EP EP11006169A patent/EP2383267A1/de not_active Withdrawn
- 2007-09-27 WO PCT/EP2007/008417 patent/WO2008040492A1/de active Application Filing
- 2007-09-27 MX MX2009003382A patent/MX2009003382A/es active IP Right Grant
- 2007-09-28 US US11/905,381 patent/US20080153843A1/en not_active Abandoned
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2009
- 2009-03-26 IL IL197814A patent/IL197814A0/en unknown
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- 2009-03-30 CO CO09032332A patent/CO6170358A2/es active IP Right Grant
- 2009-04-28 ZA ZA2009/02915A patent/ZA200902915B/en unknown
- 2009-12-09 HK HK09111546.7A patent/HK1132266A1/xx not_active IP Right Cessation
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2010
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20100113417A1 (en) * | 2008-10-29 | 2010-05-06 | Gruenenthal Gmbh | Substituted Spiroamine Compounds |
| US8278319B2 (en) | 2008-10-29 | 2012-10-02 | Gruenenthal Gmbh | Substituted spiroamine compounds |
| US20100152158A1 (en) * | 2008-11-06 | 2010-06-17 | Gruenenthal Gmbh | Substituted Disulfonamide Compounds |
| US8119805B2 (en) | 2008-11-06 | 2012-02-21 | Gruenenthal Gmbh | Substituted disulfonamide compounds |
| WO2011125967A1 (ja) | 2010-04-05 | 2011-10-13 | 塩野義製薬株式会社 | カテコール基を有するセフェム化合物 |
| US8680159B2 (en) | 2010-09-22 | 2014-03-25 | Gruenenthal Gmbh | Bradykinin 1 receptor modulating compounds |
| WO2018212534A1 (en) | 2017-05-17 | 2018-11-22 | Legochem Biosciences, Inc. | Novel compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same |
| CN109810031A (zh) * | 2017-11-21 | 2019-05-28 | 乳源瑶族自治县东阳光生物科技有限公司 | 非罗考昔中间体的制备方法 |
| WO2023028056A1 (en) | 2021-08-24 | 2023-03-02 | Genentech, Inc. | 3-amino piperidyl sodium channel inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100324009A1 (en) | 2010-12-23 |
| DK2066659T3 (da) | 2013-12-09 |
| RU2009115960A (ru) | 2010-11-10 |
| MX2009003382A (es) | 2009-04-08 |
| AU2007304475B2 (en) | 2012-07-26 |
| CO6170358A2 (es) | 2010-06-18 |
| CY1114669T1 (el) | 2016-10-05 |
| AU2007304475A1 (en) | 2008-04-10 |
| CA2664810A1 (en) | 2008-04-10 |
| HRP20130958T1 (hr) | 2013-11-22 |
| EP2066659B1 (de) | 2013-08-28 |
| HK1132266A1 (en) | 2010-02-19 |
| SI2066659T1 (sl) | 2013-10-30 |
| JP2010504930A (ja) | 2010-02-18 |
| IL197814A0 (en) | 2009-12-24 |
| ZA200902915B (en) | 2010-02-24 |
| PT2066659E (pt) | 2013-11-07 |
| WO2008040492A1 (de) | 2008-04-10 |
| NZ575566A (en) | 2011-05-27 |
| BRPI0714764A2 (pt) | 2014-12-30 |
| NO20091299L (no) | 2009-04-29 |
| PL2066659T3 (pl) | 2014-01-31 |
| CN101553481A (zh) | 2009-10-07 |
| KR20090079914A (ko) | 2009-07-22 |
| US20100317644A1 (en) | 2010-12-16 |
| ES2436020T3 (es) | 2013-12-26 |
| RU2462464C2 (ru) | 2012-09-27 |
| US8435978B2 (en) | 2013-05-07 |
| JP5405303B2 (ja) | 2014-02-05 |
| EP2383267A1 (de) | 2011-11-02 |
| EP2066659A1 (de) | 2009-06-10 |
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