US20050158362A1 - Polymeric, fiber matrix delivery systems for bioactive compounds - Google Patents

Polymeric, fiber matrix delivery systems for bioactive compounds Download PDF

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Publication number
US20050158362A1
US20050158362A1 US10/312,189 US31218905A US2005158362A1 US 20050158362 A1 US20050158362 A1 US 20050158362A1 US 31218905 A US31218905 A US 31218905A US 2005158362 A1 US2005158362 A1 US 2005158362A1
Authority
US
United States
Prior art keywords
bioactive compound
polymeric
bioactive
fibers
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/312,189
Other languages
English (en)
Inventor
Margaret Wheatley
Frank Ko
Dalia El-Sherif
Nikhil Dhoot
Saravanan Kanakasabai
Meriem Benjelloun
Baohua Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drexel University
Original Assignee
Wheatley Margaret A.
Ko Frank K.
Dalia El-Sherif
Nikhil Dhoot
Saravanan Kanakasabai
Meriem Benjelloun
Baohua Han
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wheatley Margaret A., Ko Frank K., Dalia El-Sherif, Nikhil Dhoot, Saravanan Kanakasabai, Meriem Benjelloun, Baohua Han filed Critical Wheatley Margaret A.
Priority to US10/312,189 priority Critical patent/US20050158362A1/en
Publication of US20050158362A1 publication Critical patent/US20050158362A1/en
Assigned to DREXEL UNIVERSITY reassignment DREXEL UNIVERSITY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DHOOT, NIKHIL, HAN, BAOHUA, KANAKASABAI, SARAVANAN, KO, FRANK K., WHEATLEY, MARGARET A.
Assigned to DREXEL UNIVERSITY reassignment DREXEL UNIVERSITY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BENJELLOUN, MERIEM, EL-SHERIF, DALIA
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
US10/312,189 2000-06-23 2001-06-25 Polymeric, fiber matrix delivery systems for bioactive compounds Abandoned US20050158362A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/312,189 US20050158362A1 (en) 2000-06-23 2001-06-25 Polymeric, fiber matrix delivery systems for bioactive compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21403400P 2000-06-23 2000-06-23
PCT/US2001/041133 WO2002000149A1 (fr) 2000-06-23 2001-06-25 Systemes d'administration a matrice de fibres polymeres pour composes bioactifs
US10/312,189 US20050158362A1 (en) 2000-06-23 2001-06-25 Polymeric, fiber matrix delivery systems for bioactive compounds

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/128,036 Continuation US7016883B2 (en) 2002-04-23 2002-04-23 Reverse caching for residential end-users to reduce usage of access links to a core communication network

Publications (1)

Publication Number Publication Date
US20050158362A1 true US20050158362A1 (en) 2005-07-21

Family

ID=22797516

Family Applications (2)

Application Number Title Priority Date Filing Date
US10/312,189 Abandoned US20050158362A1 (en) 2000-06-23 2001-06-25 Polymeric, fiber matrix delivery systems for bioactive compounds
US09/895,674 Expired - Fee Related US6753311B2 (en) 2000-06-23 2001-06-28 Collagen or collagen-like peptide containing polymeric matrices

Family Applications After (1)

Application Number Title Priority Date Filing Date
US09/895,674 Expired - Fee Related US6753311B2 (en) 2000-06-23 2001-06-28 Collagen or collagen-like peptide containing polymeric matrices

Country Status (3)

Country Link
US (2) US20050158362A1 (fr)
AU (1) AU2001273632A1 (fr)
WO (1) WO2002000149A1 (fr)

Cited By (12)

* Cited by examiner, † Cited by third party
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US20060200232A1 (en) * 2005-03-04 2006-09-07 Phaneuf Matthew D Nanofibrous materials as drug, protein, or genetic release vehicles
DE102006061539A1 (de) * 2006-12-27 2008-07-03 Paul Hartmann Ag Medizinisches Flächengebilde
US20090192609A1 (en) * 2008-01-29 2009-07-30 Zimmer, Inc. Implant device for use in an implant system
US20100008994A1 (en) * 2006-05-09 2010-01-14 The University Of Akron Electrospun structures and methods for forming and using same
EP2644191A1 (fr) * 2012-03-30 2013-10-02 Universitat Politécnica De Catalunya Membrane non tissée en tant que système d'administration de médicament
WO2013165604A1 (fr) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Électrotraitement d'ingrédients pharmaceutiques actifs
US8771582B2 (en) 2005-03-04 2014-07-08 BioScurfaces, Inc. Electrospinning process for making a textile suitable for use as a medical article
US9205089B2 (en) 2011-04-29 2015-12-08 Massachusetts Institute Of Technology Layer processing for pharmaceuticals
US20160106878A1 (en) * 2013-05-22 2016-04-21 The Penn State Research Foundation Wound Dressings and Applications Thereof
US10213960B2 (en) 2014-05-20 2019-02-26 Massachusetts Institute Of Technology Plasticity induced bonding
US10328032B2 (en) 2005-03-04 2019-06-25 Biosurfaces, Inc. Nanofibrous materials as drug, protein, or genetic release vehicles
JP2021532911A (ja) * 2018-08-03 2021-12-02 セビオテックス，エス．エル． 薬物送達システムとしてのビーズ不織布膜

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US6821479B1 (en) * 2001-06-12 2004-11-23 The University Of Akron Preservation of biological materials using fiber-forming techniques
US7105124B2 (en) * 2001-06-19 2006-09-12 Aaf-Mcquay, Inc. Method, apparatus and product for manufacturing nanofiber media
DE10157124A1 (de) * 2001-11-21 2003-05-28 Lohmann Therapie Syst Lts Mikrofaserhaltige Vorrichtung zur kontrollierten Freisetzung von Stoffen
US20030180268A1 (en) * 2002-02-05 2003-09-25 Anthony Atala Tissue engineered construct for supplementing or replacing a damaged organ
US20040115771A1 (en) * 2002-09-27 2004-06-17 Thomas Jefferson University Recombinant collagen-like proteins
EP1624953B1 (fr) * 2003-04-23 2018-12-19 The University of Akron Matieres reactives sequestrees
FI20045260A (fi) * 2003-11-18 2005-05-19 Teknillinen Korkeakoulu Menetelmä kuiturakenteen valmistamiseksi
WO2005052056A1 (fr) * 2003-11-25 2005-06-09 Asahi Kasei Life & Living Corporation Film mat
US20060229735A1 (en) * 2004-10-15 2006-10-12 The Cleveland Clinic Foundation Device for tissue engineering
SG123727A1 (en) * 2004-12-15 2006-07-26 Univ Singapore Nanofiber construct and method of preparing thereof
EP1863546B1 (fr) 2005-03-11 2015-10-07 Wake Forest University Health Sciences Production par genie tissulaire de valvules cardiaques
EP1863547B1 (fr) 2005-03-11 2016-05-11 Wake Forest University Health Sciences Vaisseaux sanguins realises par genie tissulaire
US8728463B2 (en) 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs
US7531503B2 (en) * 2005-03-11 2009-05-12 Wake Forest University Health Sciences Cell scaffold matrices with incorporated therapeutic agents
US20060204539A1 (en) * 2005-03-11 2006-09-14 Anthony Atala Electrospun cell matrices
US20060204445A1 (en) * 2005-03-11 2006-09-14 Anthony Atala Cell scaffold matrices with image contrast agents
US8048446B2 (en) * 2005-05-10 2011-11-01 Drexel University Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds
US7704347B2 (en) * 2005-05-27 2010-04-27 Prairie Packaging, Inc. Reinforced plastic foam cup, method of and apparatus for manufacturing same
WO2006133118A1 (fr) * 2005-06-07 2006-12-14 The University Of Akron Structures de nanofibres pour le support de materiaux biologiques
CA2613355C (fr) * 2005-06-24 2014-04-22 Duke University Systeme d'administration directe de medicaments utilisant des biopolymeres a reponse thermique
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
KR100751547B1 (ko) 2005-11-21 2007-08-23 재단법인서울대학교산학협력재단 조직공학용 지지체 및 그 제조방법, 및 조직공학용지지체를 제조하기 위한 전기방사장치
US8334257B2 (en) 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
JP2009523494A (ja) * 2006-01-12 2009-06-25 ヒストジェニックス コーポレイション 破壊された靱帯又は腱の修復及び再構築のための、及び靱帯及び腱の損傷の処置のための方法
US20080220042A1 (en) * 2006-01-27 2008-09-11 The Regents Of The University Of California Biomolecule-linked biomimetic scaffolds
KR20080091827A (ko) * 2006-01-27 2008-10-14 더 리전트 오브 더 유니버시티 오브 캘리포니아 생물유사 스캐폴드
CA2654840A1 (fr) * 2006-06-09 2007-12-21 The Regents Of The University Of California Squelettes biomimetiques lies a une biomolecule
AU2008211549B2 (en) 2007-02-01 2012-12-06 Abraham Katzir Albumin fibers and fabrics and methods of generating and using same
US20080260794A1 (en) * 2007-02-12 2008-10-23 Lauritzen Nels J Collagen products and methods for producing collagen products
US9056151B2 (en) * 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US20100018641A1 (en) * 2007-06-08 2010-01-28 Kimberly-Clark Worldwide, Inc. Methods of Applying Skin Wellness Agents to a Nonwoven Web Through Electrospinning Nanofibers
US20100070020A1 (en) * 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
EP2160153A1 (fr) * 2007-06-11 2010-03-10 Nanovasc, Inc. Stents
US8293531B1 (en) 2007-08-31 2012-10-23 Clemson University Research Foundation Three-dimensional ex vivo system
US7799261B2 (en) * 2007-11-30 2010-09-21 Cook Incorporated Needle-to-needle electrospinning
US8795577B2 (en) 2007-11-30 2014-08-05 Cook Medical Technologies Llc Needle-to-needle electrospinning
US20100249924A1 (en) * 2009-03-27 2010-09-30 Allergan, Inc. Bioerodible matrix for tissue involvement
EP2464370B1 (fr) 2009-08-14 2017-03-29 Phasebio Pharmaceuticals, Inc. Peptides intestinaux vasoactifs modifiés
US8637109B2 (en) * 2009-12-03 2014-01-28 Cook Medical Technologies Llc Manufacturing methods for covering endoluminal prostheses
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
EP2582868B1 (fr) 2010-06-17 2018-03-28 Washington University Pièces biomédicales avec fibres alignées
CA2873553C (fr) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Utilisation de peptides intestinaux vasoactifs (piv) modifies pour traiter l'hypertension
US9175427B2 (en) 2011-11-14 2015-11-03 Cook Medical Technologies Llc Electrospun patterned stent graft covering
US20140017263A1 (en) 2012-06-28 2014-01-16 Clemson University Delivery Agents for Targeted Treatment of Elastin Degradation
EP2897561B1 (fr) 2012-09-21 2020-11-04 Washington University Timbres biomédicaux avec fibres disposées spatialement
US10154918B2 (en) 2012-12-28 2018-12-18 Cook Medical Technologies Llc Endoluminal prosthesis with fiber matrix
CN103599090A (zh) * 2013-07-30 2014-02-26 江南大学 一种多层药物缓释纳米纤维膜及其制备方法
US9795573B2 (en) 2013-09-24 2017-10-24 Clemson University Multi-step connective tissue stabilization method and stabilized tissue formed thereby
US10092679B2 (en) 2013-10-18 2018-10-09 Wake Forest University Health Sciences Laminous vascular constructs combining cell sheet engineering and electrospinning technologies
PT3177329T (pt) * 2014-08-04 2020-02-03 Univ Catalunya Politecnica Sistema para a libertação imediata de agentes ativos
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
KR101810080B1 (ko) * 2015-06-01 2017-12-19 주식회사 아모라이프사이언스 치과용 멤브레인
CN105908363B (zh) * 2016-05-12 2018-07-06 华南农业大学 一种静电喷射复合薄膜及其制备方法与应用
US10632228B2 (en) 2016-05-12 2020-04-28 Acera Surgical, Inc. Tissue substitute materials and methods for tissue repair
FI3533458T3 (fi) * 2018-03-02 2023-07-20 Upm Kymmene Corp Lääketieteellinen tuote, joka käsittää bioaktiivisen molekyylin, joka on kiinnitetty paikoilleen nanofibrilliselluloosaan, sekä menetelmä sen valmistamiseksi
CN114053249B (zh) * 2020-08-10 2023-06-02 山东百多安医疗器械股份有限公司 一种可治疗全身骨质疏松的可降解载药薄膜及其制备工艺

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Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060200232A1 (en) * 2005-03-04 2006-09-07 Phaneuf Matthew D Nanofibrous materials as drug, protein, or genetic release vehicles
US10441550B2 (en) 2005-03-04 2019-10-15 Biosurfaces, Inc. Nanofibrous materials as drug, protein, or genetic release vehicles
US10328032B2 (en) 2005-03-04 2019-06-25 Biosurfaces, Inc. Nanofibrous materials as drug, protein, or genetic release vehicles
US8771582B2 (en) 2005-03-04 2014-07-08 BioScurfaces, Inc. Electrospinning process for making a textile suitable for use as a medical article
US8574315B2 (en) * 2006-05-09 2013-11-05 The University Of Akron Electrospun structures and methods for forming and using same
US20100008994A1 (en) * 2006-05-09 2010-01-14 The University Of Akron Electrospun structures and methods for forming and using same
DE102006061539A1 (de) * 2006-12-27 2008-07-03 Paul Hartmann Ag Medizinisches Flächengebilde
US20090192609A1 (en) * 2008-01-29 2009-07-30 Zimmer, Inc. Implant device for use in an implant system
US9205089B2 (en) 2011-04-29 2015-12-08 Massachusetts Institute Of Technology Layer processing for pharmaceuticals
EP3108881A1 (fr) * 2012-03-30 2016-12-28 Universitat Politècnica De Catalunya Membrane non tissee en tant que systeme d'administration de medicament
CN108992432A (zh) * 2012-03-30 2018-12-14 加泰罗尼亚理工大学 用作药物递送系统的无纺布膜
CN104321051A (zh) * 2012-03-30 2015-01-28 加泰罗尼亚理工大学 用作药物递送系统的无纺布膜
EP2644191A1 (fr) * 2012-03-30 2013-10-02 Universitat Politécnica De Catalunya Membrane non tissée en tant que système d'administration de médicament
WO2013144206A1 (fr) 2012-03-30 2013-10-03 Universitat Politecnica De Catalunya Membrane non tissée en tant que système d'administration de médicament
US9561190B2 (en) * 2012-03-30 2017-02-07 Universitat Politecnica De Catalunya Nonwoven membrane as a drug delivery system
CN104321051B (zh) * 2012-03-30 2018-09-18 加泰罗尼亚理工大学 用作药物递送系统的无纺布膜
US20150072008A1 (en) * 2012-03-30 2015-03-12 Universitat Politecnica De Catalunya Nonwoven membrane as a drug delivery system
WO2013165604A1 (fr) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Électrotraitement d'ingrédients pharmaceutiques actifs
US20160106878A1 (en) * 2013-05-22 2016-04-21 The Penn State Research Foundation Wound Dressings and Applications Thereof
US11173227B2 (en) * 2013-05-22 2021-11-16 The Penn State Research Foundation Wound dressings and applications thereof
US10213960B2 (en) 2014-05-20 2019-02-26 Massachusetts Institute Of Technology Plasticity induced bonding
US10703048B2 (en) 2014-05-20 2020-07-07 Massachusetts Institute Of Technology Plasticity induced bonding
JP2021532911A (ja) * 2018-08-03 2021-12-02 セビオテックス，エス．エル． 薬物送達システムとしてのビーズ不織布膜
JP7389105B2 (ja) 2018-08-03 2023-11-29 セビオテックス，エス．エル． 薬物送達システムとしてのビーズ不織布膜

Also Published As

Publication number Publication date
AU2001273632A1 (en) 2002-01-08
WO2002000149A1 (fr) 2002-01-03
US6753311B2 (en) 2004-06-22
US20030021821A1 (en) 2003-01-30

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