US20040073116A1 - Gain setting in doppler haemodynamic monitors - Google Patents

Gain setting in doppler haemodynamic monitors Download PDF

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Publication number
US20040073116A1
US20040073116A1 US10/450,277 US45027703A US2004073116A1 US 20040073116 A1 US20040073116 A1 US 20040073116A1 US 45027703 A US45027703 A US 45027703A US 2004073116 A1 US2004073116 A1 US 2004073116A1
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United States
Prior art keywords
velocity
gain
band
control variable
components
Prior art date
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Abandoned
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US10/450,277
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English (en)
Inventor
Leonard Smith
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Deltex Guernsey Ltd
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Deltex Guernsey Ltd
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Assigned to DELTEX (GUERNSEY) LIMITED reassignment DELTEX (GUERNSEY) LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SMITH, LEONARD
Publication of US20040073116A1 publication Critical patent/US20040073116A1/en
Priority to US12/248,642 priority Critical patent/US8075485B2/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5269—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving detection or reduction of artifacts
    • A61B8/5276—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving detection or reduction of artifacts due to motion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A61B8/065—Measuring blood flow to determine blood output from the heart
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023—Details of receivers
    • G01S7/52033—Gain control of receivers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8979—Combined Doppler and pulse-echo imaging systems

Definitions

  • This invention relates to Doppler ultrasound haemodynamic monitors and, in particular, to the adjustment of received signal gain in such devices.
  • a byproduct of the invention is that movement of the ultrasound transducer with respect to the flow being monitored, can also be detected.
  • the invention provides a method of automatically setting signal gain in a Doppler ultrasound haemodynamic monitor, said method including the steps of:
  • predetermined limits are derived from clinical testing.
  • Preferably said method includes assessing the strength of components of the velocity spectrum whilst the overall flow velocity is high.
  • the assessment is made during systole.
  • said method further includes applying a smoothing step to said band so as to avoid rapid changes in gain setting.
  • a control variable to counts of said velocity components or bins above said predetermined level and, more preferably, above said predetermined limit but below a further, higher, predetermined limit i.e. within a band.
  • a decrement or increment is applied to said control variable according to whether said counts of said velocity components above said predetermined limit are above or below limits. If the discrepancy or error between the count and the limit is large, then a large correcting decrement or increment is applied to the control variable. If the discrepancy or error is small then a small correcting decrement or increment is applied. After application of the decrement or increment, the value of the control variable is assessed and, if this value falls outside acceptable limits, the gain is changed and the control variable is re-set to zero.
  • the correct gain set point is approached from below said set point.
  • the invention provides a method of automatically setting signal gain in a Doppler ultrasound haemodynamic monitor, said method including the steps of:
  • the invention provides a method of detecting movement of a Doppler transducer in a Doppler ultrasound haemodynamic monitor, said method including:
  • the invention provides a Doppler ultrasound haemodynamic monitor including an automatic gain setting facility constructed and arranged to operate according to the methods hereinbefore set forth.
  • FIG. 1 shows a received signal waveform from a Doppler ultrasound haemodynamic monitor with gain set correctly according to the invention and showing a plot of the acceptable number of bins in the lower part of the figure;
  • FIG. 2 shows a similar view to FIG. 1 but with the gain set too low
  • FIG. 3 shows a similar view to FIG. 1 but with the gain set too high
  • FIG. 4 shows a software flow diagram illustrating the use of a control variable to influence gain setting according to the invention.
  • the present invention is primarily concerned with setting the received signal gain in a Doppler ultrasound haemodynamic monitor. However, the invention may also be useful in indicating to the operator that the transducer, which is used to insonate the blood vessel of interest with ultrasound, has moved out of alignment with the moving blood stream.
  • Apparatus to which the invention is particularly applicable includes a probe of the general type described in published International Patent Application WO 00/61005, such a probe carrying ultrasound transmit and receive crystals on the distal end thereof.
  • the probe is located in the patient's oesophagus and aligned so that the crystals are positioned to insonate a section of the patient's descending aorta with ultrasound.
  • the received ultrasound signal is conditioned and then processed in a digital processor to give a reading of laminar flow velocity through the aorta. This velocity reading is then combined with an estimate of aorta cross-sectional area to provide an indication of cardiac output.
  • the signal Prior to digital processing, the signal must be amplified, and setting the gain of this amplification step is not a straightforward task. Whilst some form of automatic gain setting, under digital control, would be desirable, traditional automated gain setting methodologies do not take into account factors inherent in apparatus of this type. For example, blood through the aorta is pulsatile and the velocity spectrum varies significantly over the duration of each pulse. Further, the ultrasound transducer may be influenced by blood flows in other vessels in the vicinity, and will produce different output data if moved out of alignment with the flow direction. Thus a simple continuous automatic gain system, as tried in the past would, in response to movement of the transducer, merely keep increasing the gain rather than indicating to the operator that the probe has moved.
  • the present invention addresses the above problems by first recognising laminar flow i.e. a flow stream in which the majority of flow components move at a single velocity or, in practice, within a narrow velocity band. Accordingly, the first step is to assess the signal strength of a various components of the velocity spectrum and identify a band of velocity components above a predetermined magnitude.
  • the DSP section of the processor preferably analyses all forward flow components and reports those which are above a predetermined magnitude to the main processor.
  • the optimum point at which to undertake the assessment is when the blood is moving at relatively high velocity i.e. during systole, the period in which the heart is contracting.
  • the start and end of systole is determined by the main processor and, in the case of the invention herein described, velocity analysis is undertaken over the whole of systole, although it is conceivable that the analysis might be restricted to a shorter time period between the start and end of systole, for example about the time in which the blood velocity increases rapidly after the start of systole.
  • the processor counts the number of frequency bins (derived from the velocity-time plot) above a particular minimum level and sets the gain to ensure that these are kept between limits. Broadly, if the number of bins falls too low the processor moves the gain setting upwards whilst if the number of bins exceeds the preset maximum the processor moves the gain setting downwards.
  • each time the processor identifies a heartbeat complex it analyses the data between the start and end of systole to determine the maximum number of frequency bins above the predetermined limit in any single sample. If the number of bins falls below a predetermined threshold, then an increment is applied to the control variable. This increment is a large number if the discrepancy or error is large; and is small if the error or discrepancy is small. If the number of bins exceeds the threshold, then a decrement is applied to the control variable. Again the decrement may be large or small, depending on the magnitude of the error or discrepancy.
  • the value of the control variable is then assessed. If it falls within prescribed limits then the gain setting is left unchanged. If, however, the value of the control variable falls outside the limits then the gain is changed upwards or downwards as appropriate. With any change of gain the control variable is reset to zero and the process then repeated.
  • control variable is simply a number, and the thresholds and limits, in relation to which it is set, are determined empirically, through practice and experience.
  • the present invention is also useful to indicate when the transducer has moved out of alignment with the flow direction. In this situation the transducer will not be indicating such a peaky type of velocity profile. The flow will not be laminar but will be more in the nature of turbulent with velocity components being spread over a broader range.
  • the width of the velocity band can be stored.
  • any divergence of the velocity distribution from the stored profile, into a turbulent condition may indicate transducer movement and can be notified to the operator as such.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Remote Sensing (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • General Physics & Mathematics (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Control Of Amplification And Gain Control (AREA)
US10/450,277 2000-12-13 2001-12-11 Gain setting in doppler haemodynamic monitors Abandoned US20040073116A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/248,642 US8075485B2 (en) 2000-12-13 2008-10-09 Gain setting in doppler haemodynamic monitors

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0030449.3 2000-12-13
GBGB0030449.3A GB0030449D0 (en) 2000-12-13 2000-12-13 Improvements in or relating to doppler haemodynamic monitors
PCT/GB2001/005482 WO2002047554A1 (fr) 2000-12-13 2001-12-11 Reglage de gain dans des moniteurs hemodynamiques doppler

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US12/248,642 Continuation US8075485B2 (en) 2000-12-13 2008-10-09 Gain setting in doppler haemodynamic monitors

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US12/248,642 Expired - Fee Related US8075485B2 (en) 2000-12-13 2008-10-09 Gain setting in doppler haemodynamic monitors

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US (2) US20040073116A1 (fr)
EP (1) EP1345532B1 (fr)
AT (1) ATE301966T1 (fr)
AU (1) AU2002222175A1 (fr)
DE (1) DE60112792T2 (fr)
GB (1) GB0030449D0 (fr)
WO (1) WO2002047554A1 (fr)

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US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
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US8858471B2 (en) 2011-07-10 2014-10-14 Guided Therapy Systems, Llc Methods and systems for ultrasound treatment
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GB0030449D0 (en) 2001-01-24
EP1345532A1 (fr) 2003-09-24
DE60112792D1 (de) 2005-09-22
AU2002222175A1 (en) 2002-06-24
US8075485B2 (en) 2011-12-13
EP1345532B1 (fr) 2005-08-17
ATE301966T1 (de) 2005-09-15
WO2002047554A1 (fr) 2002-06-20

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