Connect public, paid and private patent data with Google Patents Public Datasets

Methods and devices for implanting cardiac valves

Download PDF

Info

Publication number
US20020151970A1
US20020151970A1 US10160885 US16088502A US2002151970A1 US 20020151970 A1 US20020151970 A1 US 20020151970A1 US 10160885 US10160885 US 10160885 US 16088502 A US16088502 A US 16088502A US 2002151970 A1 US2002151970 A1 US 2002151970A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
valve
displacer
catheter
cardiac
fig
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10160885
Inventor
Michi Garrison
Hanson Gifford
Frederick St. Goar
Original Assignee
Garrison Michi E.
Gifford Hanson S.
St. Goar Frederick G.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2427Devices for manipulating or deploying heart valves during implantation
    • A61F2/243Deployment by mechanical expansion
    • A61F2/2433Deployment by mechanical expansion using balloon catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2427Devices for manipulating or deploying heart valves during implantation
    • A61F2/2436Deployment by retracting a sheath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008Fixation appliances for connecting prostheses to the body
    • A61F2220/0016Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0059Additional features; Implant or prostheses properties not otherwise provided for temporary
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006Additional features; Implant or prostheses properties not otherwise provided for modular
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/902Method of implanting
    • Y10S623/904Heart

Abstract

The valve implantation system has a valve displacer for displacing and holding the native valve leaflets open in a first aspect of the invention. A replacement valve may be attached to the valve displacer before or after introduction and may be positioned independent of the valve displacer. In another aspect of the invention, the valve displacer and valve are in a collapsed condition during introduction and are expanded to deploy the valve displacer and valve. The valve is a tissue valve mounted to an expandable support structure. The support structure may have protrusions for engaging the valve displacer or barbs for anchoring the valve displacer to the heart or blood vessel. A temporary valve mechanism may be used to provide temporary valve functions during and after deployment of the valve displacer.

Description

    BACKGROUND OF THE INVENTION
  • [0001]
    The present invention is directed to methods and devices for implanting replacement cardiac valves. Replacement cardiac valves are implanted when the patient's native valve exhibits abnormal anatomy and function due to congential or acquired valve disease. Congenital abnormalities can be tolerated for years only to develop into life-threatening problems later. Acquired valve disease may result from various causes such as rheumatic fever, degenerative disorders of the valve tissue, and bacterial or fungal infections.
  • [0002]
    Valve dysfunction can be classified as either stenosis, in which the valve does not open properly, or insufficiency, in which the valve does not close properly. Stenosis and insufficiency can occur at the same time and both abnormalities increase the workload on the heart in pumping blood through the body. The ability of the heart to function with the increased workload is a major factor in determining whether the valve should be replaced.
  • [0003]
    When the valve must be replaced using conventional methods, the patient must undergo an invasive, traumatic surgical procedure. The patient's chest is opened with a median sternotomy or major thoracotomy to provide direct access to the heart through the large opening in the chest. The heart is then stopped and the patient is placed on cardiopulmonary bypass using catheters and cannulae inserted directly into the heart and great vessels. The heart, or a great vessel leading to the heart, is then cut open to access and remove the malfunctioning valve. After removing the valve, the replacement valve is then sewn into place. After the new valve has been implanted, the chest is then closed and the patient is weaned off cardiopulmonary bypass support.
  • [0004]
    The conventional open-chest surgery described above is problematic in that it is highly invasive, traumatic and requires a lengthy recovery time. These drawbacks to conventional open-chest surgery prevent some patients from undergoing a valve implantation procedure even though a new cardiac valve is needed.
  • [0005]
    U.S. Pat. No. 5,370,685. U.S. Pat. No. 5,411,552 and U.S. Pat. No. 5,718,725, which are hereby incorporated by reference, describe devices and methods for implanting a new cardiac valve without requiring a median sternotomy or major thoracotomy. Such devices and methods reduce the pain, trauma and recovery time as compared to conventional open-chest surgery.
  • [0006]
    An object of the present invention is to provide additional devices and methods which reduce the trauma associated with conventional open-chest methods and devices for implanting cardiac valves.
  • SUMMARY OF THE INVENTION
  • [0007]
    In accordance with the object of the invention, a system and method for implanting a cardiac valve is provided which does not require a median sternotomy or major thoracotomy. The devices and methods of the present invention are preferably carried out by passing the valve through a blood vessel, preferably the femoral artery, so that the median sternotomy or major thoracotomy is not required. Alternatively, the systems of the present invention also permit introduction of the valve through a small incision between the patient's ribs without cutting the ribs or sternum.
  • [0008]
    In a first aspect of the invention, a valve displacer is used to hold the native valve leaflets open so that the native valve does not need to be removed. The valve displacer is preferably introduced into the patient in a collapsed condition and expanded to displace and hold the leaflets open. The valve displacer may either be expanded with an expansion mechanism, such as a balloon, or may be self-expanding. In a preferred embodiment, the valve displacer has a first end, a second end and a central section between the first and second ends. The first and second ends are preferably flared outwardly to form a circumferential recess around the central portion. The native leaflets are trapped within the recess when the valve displacer is deployed.
  • [0009]
    In another aspect of the invention, the valve is also introduced into the patient in a collapsed condition and expanded within the patient. The valve may either be expanded with an expansion mechanism, such as a balloon, or may be self-expanding. The cardiac valve may be coupled to the valve displacer or may be positioned independent from the valve displacer while still substantially performing the functions of the native valve. For instance, a replacement aortic valve may be positioned in the ascending or descending aorta to substantially perform the functions of the native aortic valve.
  • [0010]
    The cardiac valve is preferably delivered separate from the valve displacer but may also be integrated with the valve displacer during introduction and deployment. In a preferred embodiment, the valve has protrusions which engage openings in the valve displacer. In another embodiment, the valve has sharp elements or barbs which either pierce the native valve tissue or engage the sides of the openings in the valve displacer.
  • [0011]
    In yet another aspect of the present invention, the valve and valve displacer are preferably introduced into the patient with a catheter system. In a preferred system, the valve displacer is mounted to a first catheter and the valve is mounted to a second catheter which passes through and is slidably coupled to the first catheter. Alternatively, the valve displacer and valve may be mounted to a single catheter. The term catheter as used herein refers to any catheter, trocar or similar device for introducing medical devices into a patient.
  • [0012]
    In still another aspect of the present invention, the valve delivery catheter has a temporary valve mechanism which provides temporary valve functions after deployment of the valve displacer. The temporary valve mechanism prevents regurgitation while the native valve is held open and before deployment of the replacement cardiac valve. The temporary valve mechanism is preferably a balloon which is inflated and deflated as necessary to permit downstream flow and prevent retrograde flow. Although it is preferred to implant the cardiac valve while the patient's heart is beating, the devices and methods of the present invention may also be used with the patient's heart stopped and the patient supported by a bypass system.
  • [0013]
    These and other advantages and aspects of the invention will become evident from the following description of the preferred embodiments and claims.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0014]
    [0014]FIG. 1A shows a system for implanting a cardiac valve.
  • [0015]
    [0015]FIG. 1B shows the system of FIG. 1A introduced through a femoral vein.
  • [0016]
    [0016]FIG. 2 shows the system of FIG. 1 with a sheath retracted to expose the cardiac valve, a valve displacer and a temporary valve mechanism.
  • [0017]
    [0017]FIG. 3 shows the valve displacer positioned between the native valve leaflets prior to expansion.
  • [0018]
    [0018]FIG. 4 shows the valve displacer expanded by a first expansion mechanism.
  • [0019]
    [0019]FIG. 5 shows the valve expanded by a second expansion mechanism into engagement with the valve displacer.
  • [0020]
    [0020]FIG. 6 shows the valve displacer and valve implanted in the native valve position.
  • [0021]
    [0021]FIG. 7 shows the valve displacer in the collapsed position.
  • [0022]
    [0022]FIG. 8 shows the valve displacer in the expanded position.
  • [0023]
    [0023]FIG. 9 shows the valve and valve displacer in the expanded position.
  • [0024]
    [0024]FIG. 10 shows the valve in a collapsed condition.
  • [0025]
    [0025]FIG. 11 is a plan view of the valve showing the leaflets.
  • [0026]
    [0026]FIG. 12 is a cross-sectional view of the catheter along line A-A of FIG. 5.
  • [0027]
    [0027]FIG. 13 shows another system for implanting another cardiac valve.
  • [0028]
    [0028]FIG. 14 is a partial cut-away view of the catheter of FIG. 13 with the valve contained in a chamber.
  • [0029]
    [0029]FIG. 15 is a cross-sectional view of the catheter along line B-B of FIG. 13.
  • [0030]
    [0030]FIG. 16 shows another system for implanting a cardiac valve.
  • [0031]
    [0031]FIG. 17 shows the system of FIG. 16 with a distal portion of the valve displacer extending from the catheter.
  • [0032]
    [0032]FIG. 18 shows the valve displacer fully deployed to hold the native leaflets open.
  • [0033]
    [0033]FIG. 19 shows the valve partially expanded with the catheter manipulated so that the valve engages the valve displacer.
  • [0034]
    [0034]FIG. 20 shows the valve fully deployed and the catheter removed.
  • [0035]
    [0035]FIG. 21 is a partial cut-away view of the catheter of FIGS. 16-19.
  • [0036]
    [0036]FIG. 22 is a cross-sectional view of the catheter along line C-C of FIG. 16.
  • [0037]
    [0037]FIG. 23 shows another system for implanting a cardiac valve with the valve displacer positioned between the native leaflets.
  • [0038]
    [0038]FIG. 24 shows the valve displacer expanded.
  • [0039]
    [0039]FIG. 25 shows the valve partially deployed within the valve displacer.
  • [0040]
    [0040]FIG. 26 shows the valve fully deployed within the valve displacer.
  • [0041]
    [0041]FIG. 27 shows the valve displacer holding the native leaflets open with the valve deployed in the ascending aorta.
  • [0042]
    [0042]FIG. 28 shows the valve displacer holding the native leaflets open with the valve deployed in the descending aorta.
  • [0043]
    [0043]FIG. 29 shows the cardiac valve of FIGS. 23-28 in the collapsed condition.
  • [0044]
    [0044]FIG. 30 shows the cardiac valve of FIGS. 23-28 in the expanded condition.
  • [0045]
    [0045]FIG. 31 shows another system for delivering a cardiac valve with the delivery catheter passing through a trocar in the ascending aorta.
  • [0046]
    [0046]FIG. 32 shows an expansion mechanism expanding the valve displacer and the valve.
  • [0047]
    [0047]FIG. 33 shows sutures being pulled to invert the valve.
  • [0048]
    [0048]FIG. 34 shows the valve being stored in a preservative solution.
  • [0049]
    [0049]FIG. 35 shows the valve inverted and in the expanded condition.
  • [0050]
    [0050]FIG. 36 shows the valve and valve displacer in the collapsed condition before being attached to one another.
  • [0051]
    [0051]FIG. 37 shows the valve and valve displacer attached to one another and mounted to the delivery catheter.
  • [0052]
    [0052]FIG. 38 shows the valve and the valve displacer in the expanded condition.
  • [0053]
    [0053]FIG. 39 shows the catheter passing through the femoral vein, into the right atrium, and through the intraatrial septum into the left atrium to access the mitral valve.
  • DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • [0054]
    Referring to FIGS. 1A, 1B and 2 a system for implanting a replacement cardiac valve is shown. The present invention is described in connection with implantation of a replacement aortic valve but is applicable to any other cardiac valve. The system 2 includes a delivery catheter 4, a cardiac valve 6 and a valve displacer 8. A protective sheath 10 covers the delivery catheter 4, cardiac valve 6 and valve displacer 8 during introduction to prevent contact between the blood vessel and the cardiac valve 6 and valve displacer 8. FIGS. 1A and 1B show the sheath 10 extending around the cardiac valve 6 and valve displacer 8 and FIG. 2 shows the sheath 10 retracted to expose the cardiac valve 6 and valve displacer 8.
  • [0055]
    The cardiac valve 6 is preferably introduced through a peripheral vessel such as the femoral artery (FIGS. 1A and 2) or femoral vein (FIG. 1B). FIG. 1B shows introduction of the catheter 2 through the femoral vein, into the right atrium, through the intraatrial septum and into the left atrium to access the mitral valve. The peripheral vessel is preferably a femoral vessel but may also be the internal jugular vein, subclavian artery, axillary artery, abdominal aorta, descending aorta or any other suitable blood vessel. As will be explained below, the delivery catheter 4 may be introduced by surgical cutdown or percutaneously using the Seldinger technique. An advantage of passing the catheter 4 through a peripheral vessel is reduced trauma to the patient as compared to the conventional open-chest procedure described above. Although it is preferred to deliver the cardiac valve 6 through a peripheral vessel, the cardiac valve 6 may also be introduced directly into the ascending aorta through a small incision between ribs. The system 2 of the present invention is small enough to deliver between the patient's ribs so that the advantages of the present invention over conventional open-chest surgery are provided even when introducing the catheter through an incision in the chest.
  • [0056]
    The valve displacer 8 is expanded within the native valve to hold the native cardiac valve leaflets 6 open. An advantage of the system 2 and method of the present invention is that the native valve does not need to be removed. The replacement cardiac valves described herein may, of course, also be used when removing the native valve rather than using the valve displacer 8. Furthermore, the valve displacer 8 and cardiac valve 6 may be integrated into a single structure and delivered together rather than separately. Thus, all features of any valve displacer described herein may also form part of any of the cardiac valves described herein without departing from the scope of the invention.
  • [0057]
    The valve displacer 8 is shown in the collapsed condition in FIGS. 3 and 7 and in the expanded condition in FIGS. 4 and 8. When in the collapsed position, the valve displacer 8 forms a number of longitudinal slots 12 which form openings 14 in the valve displacer 8 when in the expanded condition. The valve displacer 8 is substantially cylindrical in the collapsed condition to facilitate introduction into the patient.
  • [0058]
    Referring to FIG. 8, first and second ends 16, 18 of the valve displacer 8 flare outwardly to form a circumferential recess 24 at a central section 22. The native leaflets are trapped in the recess 24 when the valve displacer 8 is deployed. The first end 16 has three extensions 20 extending from the central section 22. The valve displacer 8 may be made of any suitable material and preferred materials include stainless steel, nitinol, keviar, titanium, nylon and composites thereof. The valve displacer 8 may also be coated with an antithrombogenic coating. The valve displacer 8 is preferably formed from a solid hypotube by etching or micromachining, machining from a solid material, or welding wire elements together. Although it is preferred to provide the flared ends 16, 18, the valve displacer 8 may have any other suitable shape which holds the leaflets open. The valve displacer 8 may also have a fabric cover 17 which can trap calcium fragments which might break free from the valve when the valve displacer is deployed. The cover 17 is preferably made of a polyesther knit material, such as dacron, but may be made of any other suitable material.
  • [0059]
    The cardiac valve 6 has an expandable support structure 26 which moves from the collapsed position of FIGS. 4 and 10 to the expanded position of FIGS. 5 and 9. The support structure 26 is preferably formed with first and second elongate members 28, 30 which are wound to form windings 31, preferably about 12-18 windings 31, around the circumference of the valve 6. The first and second elongate members 28, 30 are attached to one another at windings 31 which forms three posts 32 extending from the support structure 26.
  • [0060]
    The support structure 26 has a protrusion 34, preferably three, extending outwardly to form an interrupted lip around an end 35 of the support structure 26. The protrusions 34 engage the openings 14 in the valve displacer 8 as shown in FIG. 9 to secure the cardiac valve 6 to the valve displacer 8. The protrusions 34 are preferably formed by a coil 36 wrapped around the loops 31 in the elongate member 30. As will be described below, the support structure 26 may also have barbs to secure the cardiac valve 6 to the valve displacer 8 or to the blood vessel wall. The cardiac valve 6 may also engage the valve displacer 8 with any other suitable connection.
  • [0061]
    The posts 32 support a valve portion 38 which performs the functions of the patient's malfunctioning native valve. Referring to FIGS. 10 and 11, the valve portion 38 is preferably a stentless tissue valve such as a tri-leaflet 39 stentless porcine valve. The valve portion 38 has a base 41 which is secured to the support structure 26 with sutures (not shown). The valve portion 38 may be stored separately from support structure 26 and attached to the support structure 26 before the procedure. Although it is preferred to provide a tissue valve for the valve portion 38, the valve portion 38 may also be made of a flexible, synthetic material. For example, the valve portion 38 may be made of polyurethane similar to the valves described in “A Tricuspid Polyurethane Heart Valve as Alternative to Mechanical Prostheses or Bioprostheses.” by Lo et al., Trans Am Society of Artificial Internal Organs, 1988; 34: pgsvalve displacer 839-844, and “Evaluation of Explanted Polyurethane Trileaflet Cardiac Valve Prostheses,” Journal Thoracic Cardiovascular Surgery, 1988; 94: pgs 419-429.
  • [0062]
    Referring to FIGS. 2-4, the delivery catheter 4 has a temporary valve mechanism 40 which provides temporary valve functions during and/or after deployment of the valve displacer 8. The temporary valve mechanism 40 ensures proper blood flow regulation when the leaflets are held open by the valve displacer 8 to provide time for accurate positioning and deployment of the valve 6. The temporary valve mechanism 40 is preferably a balloon 44 coupled to an inflation mechanism 47 controlled by a control system 42. The control system 42 senses the patient's heartbeat to time balloon inflation and deflation to permit and prevent flow in the same manner as the native valve. Similar systems for synchronizing inflation and deflation of a balloon with the patient's heartbeat are known in balloon pump technology and are described in U.S. Pat. Nos. 5,817,001, 5,413,549 and 5,254,097 which are hereby incorporated by reference. The balloon 44 is preferably inflated with a gas for quick inflation and deflation. The temporary valve mechanism 40 is preferably the balloon 44 but may also be a passive mechanical valve which automatically opens and closes due to blood flow forces.
  • [0063]
    The catheter 4 may also include an elongate balloon 45 to help pump blood through the patient's body like a blood pump. The balloon 45 is also coupled to an inflation mechanism 49 controlled by the control system 42 which inflates and deflates the balloon 45 to provide pumping assistance to the patient's heart. Balloon pump technology is described in the above-mentioned patents. The elongate balloon 45 may be replaced by any other suitable blood pump, such as a centrifugal pump having an impeller, without departing from the scope of the invention.
  • [0064]
    The temporary valve mechanism 40 and balloon 45 are, of course, only necessary when implanting the valve with the patient's heart beating. If the patient's heart is stopped and the patient is supported by a bypass system during the valve implantation procedure, the temporary valve mechanism 40 and/or balloon 45 may be used after the procedure for emergency valve functions or pumping assistance. The balloon 44 is preferably positioned in the ascending or descending aorta and the balloon 45 is preferably positioned in the descending aorta.
  • [0065]
    Referring to FIGS. 3-6, the delivery catheter 4 also has first and second expandable members 46, 48 which deploy the valve displacer 8 and cardiac valve 6, respectively. The expandable members 46, 48 are preferably balloons 50, 52 but may also be mechanically actuated devices. The balloons 50, 52 are coupled to inflation lumens 54, 56 through which inflation fluid is delivered from sources of inflation fluid 58, 60, respectively. The balloon 50 expands greater at the ends to form the flared ends 16, 18 of the valve displacer 8.
  • [0066]
    The delivery catheter 4 includes a first catheter 62, which carries the valve displacer 8, and a second catheter 64, which carries the cardiac valve 6. Referring to FIGS. 2 and 12, the second catheter 64 has a passageway 66 which receives the first catheter 62. A hemostasis valve 68 permits slidable movement between the first and second catheters 62, 64. The first catheter 62 has lumen 54 for inflating balloon 50 and the second catheter 64 has lumen 48 for inflating balloon 52. The second catheter 64 also has a lumen 51 for inflating balloon 44 and a lumen 53 for inflating balloon 45. The first catheter 62 also has a main lumen 70 which receives a guidewire 72.
  • [0067]
    The slidable connection between the first and second catheters 62, 64 permits introduction of the first catheter 62 over the guidewire 72 with the second catheter 64 being advanced over the first catheter 62 after the valve displacer 8 is in the ascending aorta. In this manner, the first catheter 62 may be advanced more easily over the guidewire 72 and through the patient's vasculature, such as around the aortic arch, as compared to a single, multichannel catheter having all features of the first and second catheters 62, 64. The first and second catheters 62, 64 may be wire-reinforced (not shown) catheters constructed in the manner described in Published PCT Application WO 97/32623 entitled “Cannula and Method of Manufacture and Use” which is hereby incorporated by reference.
  • [0068]
    A method of implanting a cardiac valve 6 in accordance with the present invention is now described in connection with FIGS. 1-6. Although the method is described in connection with the system described above, the method may be practiced with other suitable devices, including the devices and systems described below, without departing from the scope of the invention. Furthermore, the method is described in connection with replacing the aortic valve, however, the method may also be applied to other other cardiac valves such as the mitral, tricuspid and pulmonary valves.
  • [0069]
    Before implanting the cardiac valve 6, it may be desirable to perform valvuloplasty to break up pathologic adhesions between the native valve leaflets. Breaking up adhesions ensures that the valve displacer 8 expands fully to provide a large blood flow path. Valvuloplasty is preferably performed with a balloon which is inflated to open the leaflets and break the adhesions. The native cardiac valve and annulus are also sized to determine the proper size valve displacer 8 and cardiac valve 6. Sizing may be carried out using fluoroscopy, intravascular ultrasound or with any other suitable device during or after the valvuloplasty. Size parameters to consider include the cross-sectional profile through the valve, the length and size of the valve leaflets and position of the coronary ostia.
  • [0070]
    The delivery catheter 4 is preferably introduced into the patient by surgical cutdown in the femoral artery but may also be introduced percutaneously using the Seldinger technique. As mentioned above, the delivery catheter 4 may also be introduced into any other suitable vessel or through a small incision in the chest. The first and second catheters 62, 64 are advanced into the artery through the cutdown a short distance. The guidewire 72 is then advanced ahead of the first and second catheters 62, 64 up the descending aorta, around the aortic arch, into the ascending aorta and across the aortic valve. The first catheter 62 is then advanced over the guidewire 72 to the ascending aorta with the sheath 10 covering the first catheter 62 to prevent contact between the valve displacer 8 and the blood vessel or native valve. The second catheter 64 is then advanced over the first catheter 62 to position the cardiac valve 6 in the ascending aorta. The sheath 10 also prevents contact between the cardiac valve 6 and vessel wall when advancing the second catheter 64. The sheath 10 is then retracted as shown in FIG. 2 to expose the valve displacer 8 and the cardiac valve 6.
  • [0071]
    The valve displacer 8 is then introduced between the valve leaflets as shown in FIG. 3 and the balloon 50 is inflated to expand the valve displacer as shown in FIG. 4. The valve displacer 8 holds the native valve leaflets open so that the native valve does not have to be removed. When the valve displacer 8 has been deployed, the temporary valve mechanism 40 provides temporary valve functions by inflating and deflating the balloon 44 at appropriate times to permit and block flow in the same manner as the native valve. The balloon 45 may also be inflated and deflated to provide pumping assistance to the patient's heart during the procedure. Although the above-described method is performed with the patient's heart beating, the procedure may also be performed on a stopped heart with the patient supported by a bypass system.
  • [0072]
    The second catheter 64 is then advanced until the valve 6 is positioned adjacent the valve displacer 8. Although FIG. 5 shows the first catheter 62 extending into the left ventricle, the first catheter 62 may also be designed to be withdrawn into the passageway 66 of the second catheter 64 so that the first catheter 62 does not extend beyond the second catheter 64. The balloon 52 is then partially inflated so that the distal end of the valve 6 having the protrusions 34 expands. The second catheter 64 is then manipulated until the protrusions 34 engage the openings 14 in the valve displacer 8. The balloon 52 is then inflated further to expand the rest of the support structure 26. The catheters 62, 64 are then removed leaving the cardiac valve 6 in place.
  • [0073]
    Referring to FIGS. 13 and 14, another system 2A for implanting a cardiac valve 6A is shown wherein the same or similar reference numbers refer to the same or similar structures. The cardiac valve 6A is similar to the cardiac valve 6 described above, however, the cardiac valve 6A is self-expanding and, therefore, does not require an independent expansion mechanism. The support structure 26A is made of a resilient material to naturally bias the support structure 26A to the expanded position. The support structure 26A may be made of any suitable material and preferred materials are stainless steel or shape-memory alloys such as nitinol. Delivery catheter 4A has the expandable member 46, which is preferably the balloon 50, for expanding the valve displacer 8.
  • [0074]
    The cardiac valve 6A is contained within an outer wall 74 of the delivery catheter 4A. The cardiac valve 6A is advanced out of a chamber 76 in the delivery catheter 4A by advancing a rod 78 having a pusher element 80 attached thereto. The pusher element 80 engages the posts 82 on the cardiac valve 6A to move the cardiac valve 6A out of the chamber 76. The rod 78 has threaded connections 80, 82 with a tip 84 and the pusher element 80 to facilitate assembling the delivery catheter 4A and loading the cardiac valve 6A in the chamber 76. The rod 78 has a guidewire lumen 86 for receiving the guidewire 72. Referring to the cross-sectional view of FIG. 15, the catheter 4A has a first lumen 88 coupled to the balloon 50, a second lumen 90 coupled to the balloon 44 and a third lumen 91 coupled to the balloon 45. The second and third lumens 88, 90 are coupled to the inflation mechanisms 47, 29 which are controlled by the control system 42 described in connection with FIGS. 1 and 2. The system 2A preferably includes the sheath 10 which prevents contact between the blood vessel and the valve displacer 8 when the catheter 4A is advanced through the blood vessel.
  • [0075]
    The cardiac valve 6A is implanted in substantially the same manner as the cardiac valve 6 and the discussion of implantation of the cardiac valve 6 is also applicable here. The delivery catheter 4A may be introduced in any manner described herein and FIG. 13 shows the catheter 4A extending through the femoral artery with the valve displacer 8 positioned between the valve leaflets prior to expansion. The valve displacer 8 is expanded in the manner explained above to hold the leaflets open. After the valve displacer 8 has been expanded, the catheter 4A is retraced a predetermined amount so that the protrusions 34 are exposed outside the distal end of the catheter 4A. The catheter 4A may then be manipulated as necessary so that the protrusions 34 engage the openings 14 in the valve displacer 8. The valve 6A preferably remains coupled to the catheter 4A while the protrusions 34 are exposed for manipulation of the valve 6A until the valve 6A engages the valve displacer 8. After the valve 6A has engaged the valve displacer 8, the rod 78 is then advanced far enough to completely release the cardiac valve 6A.
  • [0076]
    Referring to FIGS. 16-22, another system 4B for implanting the cardiac valve 4A is shown wherein the same or similar reference numbers refer to the same or similar structure. The system has the self-expanding cardiac valve 4A described above. The valve displacer 8B is similar to the valve displacer 8 described above, however, the valve displacer 8B is also self-expanding and, therefore, does not require an independent expansion mechanism. The valve displacer 8B is made of a resilient material to naturally bias the valve displacer 8B to the expanded position. The valve displacer 8B may be made of any suitable material and preferred materials are stainless steel and shape-memory alloys such as nitinol.
  • [0077]
    The valve displacer SB and cardiac valve 6A are contained within an outer wall 74 of the delivery catheter 4B as shown in FIG. 21. The valve displacer 8B and cardiac valve 4A are advanced out of a chamber 76B in the delivery catheter 4B by advancing a rod 78B having first and second pusher elements 80B. 81B attached thereto. The rod 78B has threaded connections 79B. 82B, and 83B with the tip 84 and the first and second pusher elements 80B. 81B to facilitate assembling catheter 4B and loading the valve displacer 8B and cardiac valve 6A in the chamber 76B. The rod 78B has the guidewire lumen 86 for receiving the guidewire 72 (FIG. 14). Referring to FIG. 16 and the cross-sectional view of FIG. 22, the catheter 4B has a lumen 90 coupled to the balloon 44 which serves as the temporary valve mechanism 40 and a lumen 93 which is coupled to the balloon 45. The lumen 90 and lumen 93 are coupled to the inflation mechanisms 47, 29 which are controlled by the control system 42 (FIGS. 1A, 1B, and 2).
  • [0078]
    Another method of implanting a cardiac valve is now described with reference to FIGS. 16-20 wherein the same or similar reference numbers refer to the same or similar struture. The method describes use of the delivery catheter 4B and cardiac valve 6A, however, the method may be practiced using other suitable structures. The delivery catheter 4B is introduced in any manner described above and is preferably introduced through the femoral artery. The guidewire 72 is advanced ahead of the catheter 4B into the ascending aorta and the delivery catheter 4B is advanced over the guidewire 72. The delivery catheter 4B is then advanced between the valve leaflets. A distal end of the valve displacer 8B is then advanced out of the chamber 76 and the catheter 4B is retracted until the valve displacer 8 contacts the valve opening. The catheter 4B is then retracted while the rod 78B is maintained in the same position so that the valve displacer 8B emerges from the chamber 76B as shown in FIG. 18. The catheter 4B is then advanced a predetermined amount and the rod is advanced to force a distal end of the valve 6A from the chamber 76B. The catheter 4B is then moved as necessary so that the protrusions 34 engage the openings 14 in the valve displacer 8 as shown in FIG. 19. The catheter 4B is then withdrawn further so that the support structure 26A expands to the fully deployed position of FIG. 20. The catheter 4B is then removed leaving the cardiac valve 6A as shown in FIG. 20 During the procedure described above, the temporary valve mechanism 40 provides temporary valve functions while the balloon 45 provides pumping assistance as described above.
  • [0079]
    Referring to FIGS. 23-30, another system 2C for implanting a cardiac valve 6C is shown. The system 2C includes the valve displacer 8 and delivery catheter 4 described above. The delivery catheter 4 has the balloon 50 for inflating the valve displacer 8, the balloon 52 for inflating a cardiac valve 6C, the temporary valve mechanism 40 and the balloon 45. The cardiac valve 6C is similar to the cardiac valves 6, 6A except that the cardiac valve 6C has barbs 100 which extend outwardly from the cardiac valve 6C in the expanded condition of FIG. 30. The barbs 100 secure the cardiac valve 6C to the valve displacer 8 or directly to the vessel wall. The cardiac valve 6C has depressions 102 so that the barbs 100 are recessed from an outer surface 104 of the cardiac valve 6C when in the collapsed position of FIG. 29. The depressions 102 prevent the barbs 100 from interfering with smooth retraction of the sheath 10. When the cardiac valve 6C is expanded, the depressions 102 and barbs 100 rotate and move outwardly to engage the valve displacer 8 or vessel wall.
  • [0080]
    The system 2C is introduced into the patient in any manner described above and FIG. 23 shows the delivery catheter 4 passing through the femoral artery. The valve displacer 8 is deployed in the manner described above wherein the valve displacer 8 is introduced into the valve leaflets and expanded with the balloon 50 to hold the native leaflets open as shown in FIG. 24. The delivery catheter 4 may then be advanced so that the cardiac valve 6C is expanded in the valve displacer 8 with the barbs 100 passing into the openings 14 to secure the cardiac valve 6C to the valve displacer 8 as shown in FIGS. 25 and 26. The barbs 100 may be long enough to pierce and anchor in the native valve leaflets or may be designed to merely pass into and engage the sides of the openings 14.
  • [0081]
    The term “cardiac valve” as used herein refers to a valve which substantially replaces the function of the patient's malfunctioning cardiac valve. The valve may be positioned in the native valve position or may be positioned in a different location while still substantially performing the functions of the native valve. For example, a replacement aortic valve may be positioned superior to the coronary ostia, in the aortic arch or in the descending aorta. Such a replacement valve will substantially function like the patient's native aortic valve. Referring to FIGS. 27 and 28 the cardiac valve 6C is deployed in the ascending and descending aorta with the barbs 100 securing the cardiac valve 6C directly to the vessel wall.
  • [0082]
    Referring to FIGS. 31-38 another system 2D for introducing a valve 6D is shown wherein similar or the same reference numbers refer to similar or the same structure. The valve 6D is coupled to a valve displacer 8D prior to introduction into the patient. The valve 6D has an expandable support structure 26D which is movable from the collapsed position of FIGS. 36 and 37 to the expanded position of FIGS. 34 and 35. The support structure 26D has flexible joints 106 which bend to radially collapse the support structure 26D. The support structure 26D has protrusions 34D which engage holes 108 in the valve displacer 8D. The valve 6D and valve displacer 8D may engage one another in any other suitable manner.
  • [0083]
    The valve 6D is inverted before being attached to the valve displacer 8D as shown in FIG. 35. A number of sutures 110, preferably three, are then passed through the valve 6D. The sutures 110 are used to invert the valve after introduction into the patient as will be explained below. The valve 6D may be any of the valves described herein or any other suitable valve without departing from the scope of the invention. A circumferential ring 111 extends around the support structure 26D. The ring 111 is preferably made of stainless steel or shape-memory alloy such as nitinol and provides circumferential support of the valve against the aortic wall for hemostasis.
  • [0084]
    The valve displacer 8D is mounted to a delivery catheter 4D having a balloon 112 for expanding the valve displacer 8D and valve 6D. The balloon 112 is coupled to a source of inflation fluid 114 (FIG. 31) for inflating the balloon 112. The catheter 4D passes through a trocar 116 having a hemostasis valve 117. The sutures 110 and the catheter 4D pass through the hemostasis valve which permits slidable movements of the sutures 110 and catheter 4D.
  • [0085]
    The valve 6D is preferably stored in a preservative solution until just before the procedure as shown in FIG. 34. The valve is then inverted as shown in FIG. 35 and the sutures 110 are passed through the valve 6D. The valve 6D is then attached to the valve displacer 8D as shown in FIG. 37 and mounted to the delivery catheter 4D.
  • [0086]
    The valve 6D may be delivered in any manner described above and is preferably introduced through an incision in the patient's chest. Referring to FIGS. 31 and 32, the trocar 116 is introduced into the ascending aorta through purse-string sutures (not shown). The trocar 116 may have a chamber (not shown) in which the valve 6D is positioned when the trocar 116 is introduced into the ascending aorta. The sheath 10 (see FIGS. 1A, 1B and 2) described above may also be used to prevent contact between the valve and trocar and between the valve and the aortic wall. The valve 6D is preferably introduced with the patient's heart beating but may also be implanted with the patient's heart stopped and the patient supported by a bypass system. Although system 2D does not show the balloons 40 and 45, it is understood that the balloons 40, 45 may also be used with system 2D without departing from the scope of the invention.
  • [0087]
    After introduction of the trocar 116, the valve 6D is advanced until the valve 6D is between the native valve leaflets. The balloon 112 is then inflated to expand the valve 6D and valve displacer 8D. The catheter 4D is then removed and the sutures 110 are pulled to invert the valve 6D as shown in FIG. 33. An end of each suture 110 is then pulled to remove the sutures 110. The trocar 116 and catheter 4D are then removed leaving the valve 6D (FIG. 38).
  • [0088]
    Although the foregoing invention has been described by way of illustration and example of preferred embodiments for purposes of clarity and understanding, changes and modifications to the preferred embodiments may be incorporated without departing from the scope of the invention. For example, the native valve may be removed rather than held open with the valve displacer, the replacement cardiac valve may be a completely synthetic or mechanical valve, and the expansion mechanism may be a mechanical mechanism rather than a balloon.

Claims (29)

What is claimed is:
1. A method of implanting a cardiac valve, comprising the steps of:
introducing a valve and a valve displacer into a patient, the valve and valve displacer being movable from collapsed positions to expanded positions, the valve and valve displacer being introduced into the patient in the collapsed position;
positioning the valve displacer between valve leaflets of a native cardiac valve;
expanding the valve displacer to the expanded position after the positioning step thereby displacing and holding the valve leaflets in an open position; and
securing the valve at a desired location in the patient.
2. The method of claim 1, wherein:
the securing step is carried out with the replacement valve being secured to the valve displacer.
3 The method of claim 2, wherein:
the securing step is carried out with the valve interlocking with the valve displacer.
4. The method of claim 2, wherein:
the securing step is carried out with the valve having sharp elements which penetrate the native valve.
5. The method of claim 1, wherein:
the introducing step is carried out with the valve having a support structure and a valve portion, the support structure being expandable from a collapsed position to an expanded position, the introducing step being carried out with the support structure being in the collapsed position.
6. The method of claim 1, wherein:
the securing step is carried out with the desired valve location being spaced apart from the valve displacer.
7. The method of claim 6, wherein:
the securing step is carried out with the desired location of the valve being between the coronary ostia and the brachiocephalic artery.
8. The method of claim 1, wherein:
the introducing step is carried out with the valve displacer being mounted to a catheter.
9. The method of claim 8, further comprising the step of:
enclosing the valve displacer in a flexible sheath during the introducing step; and
uncovering the valve displacer before the expanding step.
10. The method of claim 8, wherein:
the introducing step is carried out with the catheter passing through a penetration in the aortic arch.
11. The method of claim 8, wherein:
the introducing step is carried out through the femoral artery.
12. The method of claim 1, wherein:
the introducing step is carried out with the valve being mounted on a catheter.
13. The method of claim 8, wherein:
the introducing step is carried out with the catheter having an expandable member, the valve displacer being mounted to the expandable member.
14. The method of claim 12, wherein:
the introducing step is carried out with the catheter having a valve mechanism.
15. The method of claim 12, wherein:
the introducing step is carried out with the catheter having a balloon, the balloon being coupled to a control mechanism for inflating and deflating the balloon to provide pumping assistance to the patient's heart.
16. The method of claim 1, wherein:
the introducing step is carried out with the valve displacer being mounted on a catheter.
17. The method of claim 16, wherein:
the introducing step is carried out with the catheter having an expandable member, the valve displacer being mounted to the expandable member.
18. The method of claim 14, wherein:
the introducing step is carried out the valve displacer having an end which flares outwardly when the valve displacer is in the expanded position.
19. The method of claim 1, wherein:
the introducing step is carried out with the valve displacer having a circumferential recess formed between the first end and a second end.
20. The method of claim 1, wherein:
the securing step is carried out before the introducing step so that the valve and valve displacment device are introduced together.
21. The method of claim 20, further comprising the step of:
inverting the valve after the introducing step.
22. The method of claim 1, wherein:
the valve introducing step is carried out with the valve having an expandable support structure, the expandable support structure having at least three posts extending from the expandable support structure.
23. A device for maintaining a patient's native valve leaflets open, comprising:
a first end;
a second end; and
a central section extending between the first and second ends;
the first and second ends being flared outwardly from the central section so that the central section forms a recess for receiving the native valve leaflets, the first end, second end and central section forming a structure which is movable from a collapsed condition to an expanded condition.
24. The device of claim 23, wherein:
the first end, second end and central section are integrally formed.
25. The device of claim 23, wherein:
the structure is substantially cylindrical in the collapsed condition, the first and second ends flaring outwardly from the central section when the structure is in expanded condition.
26. The device of claim 23, wherein:
the structure has a circumferential recess for retaining the native valve leaflets, the circumferential recess extending around the central section.
27. The device of claim 23, further comprising:
a valve portion attached to at least one of the first end, second end and central section, the valve portion permitting blood flow therethrough in one direction and preventing flow in the other direction.
28. The device of claim 27, wherein:
the valve portion is a tissue valve.
29. The device of claim 27, wherein:
the valve portion lockingly engages at least one of the first end, second end and central section.
US10160885 1999-02-10 2002-06-03 Methods and devices for implanting cardiac valves Abandoned US20020151970A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US09248911 US6425916B1 (en) 1999-02-10 1999-02-10 Methods and devices for implanting cardiac valves
US10160885 US20020151970A1 (en) 1999-02-10 2002-06-03 Methods and devices for implanting cardiac valves

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10160885 US20020151970A1 (en) 1999-02-10 2002-06-03 Methods and devices for implanting cardiac valves

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09248911 Division US6425916B1 (en) 1999-02-10 1999-02-10 Methods and devices for implanting cardiac valves

Publications (1)

Publication Number Publication Date
US20020151970A1 true true US20020151970A1 (en) 2002-10-17

Family

ID=22941221

Family Applications (2)

Application Number Title Priority Date Filing Date
US09248911 Active US6425916B1 (en) 1999-02-10 1999-02-10 Methods and devices for implanting cardiac valves
US10160885 Abandoned US20020151970A1 (en) 1999-02-10 2002-06-03 Methods and devices for implanting cardiac valves

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US09248911 Active US6425916B1 (en) 1999-02-10 1999-02-10 Methods and devices for implanting cardiac valves

Country Status (5)

Country Link
US (2) US6425916B1 (en)
JP (1) JP4233765B2 (en)
CA (1) CA2360185C (en)
EP (1) EP1164976A4 (en)
WO (1) WO2000047139A9 (en)

Cited By (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050075717A1 (en) * 2003-10-06 2005-04-07 Nguyen Tuoc Tan Minimally invasive valve replacement system
WO2005062980A2 (en) 2003-12-23 2005-07-14 Sadra Medical, Inc. Repositionable heart valve
US20050177182A1 (en) * 2003-12-04 2005-08-11 Van Der Burg Erik J. System and method for delivering a left atrial appendage containment device
US20050197695A1 (en) * 2004-03-03 2005-09-08 Sorin Biomedica Cardio S.R.L. Minimally-invasive cardiac-valve prosthesis
US6989027B2 (en) 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US20060020334A1 (en) * 2004-05-05 2006-01-26 Lashinski Randall T Methods of cardiac valve replacement using nonstented prosthetic valve
US20060129235A1 (en) * 1999-11-17 2006-06-15 Jacques Seguin Prosthetic valve for transluminal delivery
US20060259137A1 (en) * 2003-10-06 2006-11-16 Jason Artof Minimally invasive valve replacement system
US20060282161A1 (en) * 2003-06-20 2006-12-14 Medtronic Vascular, Inc. Valve annulus reduction system
US20070010878A1 (en) * 2003-11-12 2007-01-11 Medtronic Vascular, Inc. Coronary sinus approach for repair of mitral valve regurgitation
US20070016288A1 (en) * 2005-07-13 2007-01-18 Gurskis Donnell W Two-piece percutaneous prosthetic heart valves and methods for making and using them
WO2007048529A1 (en) * 2005-10-28 2007-05-03 Jenavalve Technology Inc. Device for implanting and fastening heart valve prostheses
WO2007058847A2 (en) 2005-11-14 2007-05-24 Sadra Medical, Inc. Medical implant deployment tool
US20080039881A1 (en) * 2006-07-07 2008-02-14 The Cleveland Clinic Foundation Apparatus and method for assisting in the removal of a cardiac valve
US20080065206A1 (en) * 2000-09-07 2008-03-13 Liddicoat John R Fixation band for affixing a prosthetic heart valve to tissue
US20080208327A1 (en) * 2007-02-27 2008-08-28 Rowe Stanton J Method and apparatus for replacing a prosthetic valve
US20080243246A1 (en) * 2007-02-16 2008-10-02 Ryan Timothy R Replacement prosthetic heart valves and methods of implantation
US20080319538A1 (en) * 2007-06-08 2008-12-25 Mykolaj Styrc Kit to be implanted in a blood circulation conduit
US20090012600A1 (en) * 2005-04-05 2009-01-08 Mikolaj Witold Styrc Kit Which Is Intended to Be Implanted in a Blood Vessel, and Associated Tubular Endoprosthesis
US20090030503A1 (en) * 2007-07-23 2009-01-29 Ho Paul C Method and apparatus for percutaneous aortic valve replacement
US20090030510A1 (en) * 2007-07-23 2009-01-29 Ho Paul C Methods and apparatus for percutaneous aortic valve replacement
US7578843B2 (en) 2002-07-16 2009-08-25 Medtronic, Inc. Heart valve prosthesis
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7682385B2 (en) 2002-04-03 2010-03-23 Boston Scientific Corporation Artificial valve
US7682390B2 (en) 2001-07-31 2010-03-23 Medtronic, Inc. Assembly for setting a valve prosthesis in a corporeal duct
US7712606B2 (en) 2005-09-13 2010-05-11 Sadra Medical, Inc. Two-part package for medical implant
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7740655B2 (en) 2006-04-06 2010-06-22 Medtronic Vascular, Inc. Reinforced surgical conduit for implantation of a stented valve therein
US7748389B2 (en) 2003-12-23 2010-07-06 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US20100174363A1 (en) * 2009-01-07 2010-07-08 Endovalve, Inc. One Piece Prosthetic Valve Support Structure and Related Assemblies
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US20100185275A1 (en) * 2009-01-12 2010-07-22 Valve Medical Ltd. Modular percutaneous valve structure and delivery method
US20100191326A1 (en) * 2007-06-26 2010-07-29 Alkhatib Yousef F Apparatus and method for implanting collapsible/expandable prosthetic heart valves
US7776053B2 (en) 2000-10-26 2010-08-17 Boston Scientific Scimed, Inc. Implantable valve system
US7780627B2 (en) 2002-12-30 2010-08-24 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US20100234940A1 (en) * 2009-03-12 2010-09-16 Medtronic Vascular , Inc. Prosthetic Valve Delivery System
US7799038B2 (en) 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US7819915B2 (en) 2000-07-27 2010-10-26 Edwards Lifesciences Corporation Heart valve holders and handling clips therefor
US7824442B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US7846199B2 (en) 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US7857845B2 (en) 2005-02-10 2010-12-28 Sorin Biomedica Cardio S.R.L. Cardiac-valve prosthesis
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7935144B2 (en) 2006-10-19 2011-05-03 Direct Flow Medical, Inc. Profile reduction of valve implant
US7951189B2 (en) 2005-09-21 2011-05-31 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US7951197B2 (en) 2005-04-08 2011-05-31 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US7959674B2 (en) 2002-07-16 2011-06-14 Medtronic, Inc. Suture locking assembly and method of use
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7959672B2 (en) 2003-12-23 2011-06-14 Sadra Medical Replacement valve and anchor
US7967853B2 (en) 2007-02-05 2011-06-28 Boston Scientific Scimed, Inc. Percutaneous valve, system and method
US7967857B2 (en) 2006-01-27 2011-06-28 Medtronic, Inc. Gasket with spring collar for prosthetic heart valves and methods for making and using them
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US7972377B2 (en) 2001-12-27 2011-07-05 Medtronic, Inc. Bioprosthetic heart valve
US7981153B2 (en) 2002-12-20 2011-07-19 Medtronic, Inc. Biologically implantable prosthesis methods of using
US7988724B2 (en) 2003-12-23 2011-08-02 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US7993392B2 (en) 2006-12-19 2011-08-09 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US8002824B2 (en) 2004-09-02 2011-08-23 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US20110224785A1 (en) * 2010-03-10 2011-09-15 Hacohen Gil Prosthetic mitral valve with tissue anchors
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
US8021161B2 (en) 2006-05-01 2011-09-20 Edwards Lifesciences Corporation Simulated heart valve root for training and testing
US8048153B2 (en) 2003-12-23 2011-11-01 Sadra Medical, Inc. Low profile heart valve and delivery system
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
WO2011139594A2 (en) 2010-04-27 2011-11-10 Medtronic, Inc. Artificial bursa for intra-articular drug delivery
US8057539B2 (en) 2006-12-19 2011-11-15 Sorin Biomedica Cardio S.R.L. System for in situ positioning of cardiac valve prostheses without occluding blood flow
US8070801B2 (en) 2001-06-29 2011-12-06 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US20120022639A1 (en) * 2010-07-21 2012-01-26 Hacohen Gil Guide wires with commissural anchors to advance a prosthetic valve
US8114154B2 (en) 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
US20120046740A1 (en) * 2004-11-05 2012-02-23 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8133213B2 (en) 2006-10-19 2012-03-13 Direct Flow Medical, Inc. Catheter guidance through a calcified aortic valve
US8133270B2 (en) 2007-01-08 2012-03-13 California Institute Of Technology In-situ formation of a valve
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
WO2012031141A3 (en) * 2010-09-01 2012-06-07 Maurice Buchbinder Cardiac valve support structure
US8211169B2 (en) 2005-05-27 2012-07-03 Medtronic, Inc. Gasket with collar for prosthetic heart valves and methods for using them
US8216299B2 (en) 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
WO2012103204A2 (en) * 2011-01-25 2012-08-02 Emory University Systems, devices and methods for surgical and precutaneous replacement of a valve
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
EP2537487A1 (en) 2003-12-23 2012-12-26 Sadra Medical, Inc. Repositionable heart valve
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8348998B2 (en) 2009-06-26 2013-01-08 Edwards Lifesciences Corporation Unitary quick connect prosthetic heart valve and deployment system and methods
US8353953B2 (en) 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
US8403982B2 (en) 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US8430927B2 (en) * 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US20130123914A1 (en) * 2010-03-01 2013-05-16 Colibri Heart Valve Llc Percutaneously deliverable heart valve and methods associated therewith
US8449625B2 (en) 2009-10-27 2013-05-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US8500798B2 (en) 2005-05-24 2013-08-06 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US8506625B2 (en) 2005-07-13 2013-08-13 Edwards Lifesciences Corporation Contoured sewing ring for a prosthetic mitral heart valve
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8568477B2 (en) 2005-06-07 2013-10-29 Direct Flow Medical, Inc. Stentless aortic valve replacement with high radial strength
US8574257B2 (en) 2005-02-10 2013-11-05 Edwards Lifesciences Corporation System, device, and method for providing access in a cardiovascular environment
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8579965B2 (en) 2001-08-03 2013-11-12 Jenavalve Technology, Inc. Methods of implanting an implantation device
US8579966B2 (en) * 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US8603161B2 (en) 2003-10-08 2013-12-10 Medtronic, Inc. Attachment device and methods of using the same
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US8641757B2 (en) 2010-09-10 2014-02-04 Edwards Lifesciences Corporation Systems for rapidly deploying surgical heart valves
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8696689B2 (en) 2008-03-18 2014-04-15 Medtronic Ventor Technologies Ltd. Medical suturing device and method for use thereof
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
DE102005052628B4 (en) * 2005-11-04 2014-06-05 Jenavalve Technology Inc. Self-expanding, flexible wire mesh with integrated valve prosthesis for the transvascular cardiac valve replacement and a system comprising such a device and a delivery catheter
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US8790398B2 (en) 2002-01-04 2014-07-29 Colibri Heart Valve Llc Percutaneously implantable replacement heart valve device and method of making same
US8808367B2 (en) 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US20140236291A1 (en) * 2012-04-19 2014-08-21 Caisson Interventional Llc Valve replacement systems and methods
US8821569B2 (en) 2006-04-29 2014-09-02 Medtronic, Inc. Multiple component prosthetic heart valve assemblies and methods for delivering them
US8828079B2 (en) 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8845720B2 (en) 2010-09-27 2014-09-30 Edwards Lifesciences Corporation Prosthetic heart valve frame with flexible commissures
US8858623B2 (en) 2011-11-04 2014-10-14 Valtech Cardio, Ltd. Implant having multiple rotational assemblies
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
WO2014189509A1 (en) * 2013-05-22 2014-11-27 Nadav Yellin Transcatheter prosthetic valve for mitral or tricuspid valve replacement
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US8986374B2 (en) 2010-05-10 2015-03-24 Edwards Lifesciences Corporation Prosthetic heart valve
US8992604B2 (en) 2010-07-21 2015-03-31 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9034033B2 (en) 2011-10-19 2015-05-19 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9050188B2 (en) 2013-10-23 2015-06-09 Caisson Interventional, LLC Methods and systems for heart valve therapy
US9078747B2 (en) 2011-12-21 2015-07-14 Edwards Lifesciences Corporation Anchoring device for replacing or repairing a heart valve
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices
US9125741B2 (en) 2010-09-10 2015-09-08 Edwards Lifesciences Corporation Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves
US9125740B2 (en) 2011-06-21 2015-09-08 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9155617B2 (en) 2004-01-23 2015-10-13 Edwards Lifesciences Corporation Prosthetic mitral valve
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9168105B2 (en) 2009-05-13 2015-10-27 Sorin Group Italia S.R.L. Device for surgical interventions
US9180008B2 (en) 2012-02-29 2015-11-10 Valcare, Inc. Methods, devices, and systems for percutaneously anchoring annuloplasty rings
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
CN105263442A (en) * 2013-02-04 2016-01-20 托尔福公司 Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9248016B2 (en) 2009-03-31 2016-02-02 Edwards Lifesciences Corporation Prosthetic heart valve system
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US9308360B2 (en) 2007-08-23 2016-04-12 Direct Flow Medical, Inc. Translumenally implantable heart valve with formed in place support
US9314334B2 (en) 2008-11-25 2016-04-19 Edwards Lifesciences Corporation Conformal expansion of prosthetic devices to anatomical shapes
US9351830B2 (en) 2006-12-05 2016-05-31 Valtech Cardio, Ltd. Implant and anchor placement
US9364326B2 (en) 2011-06-29 2016-06-14 Mitralix Ltd. Heart valve repair devices and methods
US9370418B2 (en) 2010-09-10 2016-06-21 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9387078B2 (en) 2011-08-05 2016-07-12 Mitraltech Ltd. Percutaneous mitral valve replacement and sealing
US9393111B2 (en) 2014-01-15 2016-07-19 Sino Medical Sciences Technology Inc. Device and method for mitral valve regurgitation treatment
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9402721B2 (en) 2011-06-01 2016-08-02 Valcare, Inc. Percutaneous transcatheter repair of heart valves via trans-apical access
US20160220367A1 (en) * 2015-02-04 2016-08-04 Medtronic Vascular, Inc. Balloon valvuloplasty delivery system
US9414921B2 (en) 2009-10-29 2016-08-16 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9421098B2 (en) 2010-12-23 2016-08-23 Twelve, Inc. System for mitral valve repair and replacement
US9433503B2 (en) 2010-08-04 2016-09-06 Valcare, Inc. Percutaneous transcatheter repair of heart valves
US9439762B2 (en) 2000-06-01 2016-09-13 Edwards Lifesciences Corporation Methods of implant of a heart valve with a convertible sewing ring
US9468527B2 (en) 2013-06-12 2016-10-18 Edwards Lifesciences Corporation Cardiac implant with integrated suture fasteners
US9474606B2 (en) 2009-05-04 2016-10-25 Valtech Cardio, Ltd. Over-wire implant contraction methods
US9504566B2 (en) 2014-06-20 2016-11-29 Edwards Lifesciences Corporation Surgical heart valves identifiable post-implant
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9526613B2 (en) 2005-03-17 2016-12-27 Valtech Cardio Ltd. Mitral valve treatment techniques
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9549816B2 (en) 2014-04-03 2017-01-24 Edwards Lifesciences Corporation Method for manufacturing high durability heart valve
US20170020695A1 (en) * 2005-11-10 2017-01-26 Edwards Lifesciences Cardiaq Llc Percutaneous heart valve
US9554901B2 (en) 2010-05-12 2017-01-31 Edwards Lifesciences Corporation Low gradient prosthetic heart valve
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US9579198B2 (en) 2012-03-01 2017-02-28 Twelve, Inc. Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US9585752B2 (en) 2014-04-30 2017-03-07 Edwards Lifesciences Corporation Holder and deployment system for surgical heart valves
US9610162B2 (en) 2013-12-26 2017-04-04 Valtech Cardio, Ltd. Implantation of flexible implant
US9622861B2 (en) 2009-12-02 2017-04-18 Valtech Cardio, Ltd. Tool for actuating an adjusting mechanism
US9622859B2 (en) 2005-02-01 2017-04-18 Boston Scientific Scimed, Inc. Filter system and method
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9655722B2 (en) 2011-10-19 2017-05-23 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9662207B2 (en) 2005-11-16 2017-05-30 Edwards Lifesciences Corporation Transapical method of delivering prosthetic heart valve
US9662209B2 (en) 2008-12-22 2017-05-30 Valtech Cardio, Ltd. Contractible annuloplasty structures
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
US9681952B2 (en) 2013-01-24 2017-06-20 Mitraltech Ltd. Anchoring of prosthetic valve supports
US9687345B2 (en) 2014-05-29 2017-06-27 Edwards Lifesciences Cardiaq Llc Prosthesis, delivery device and methods of use
US9700412B2 (en) 2014-06-26 2017-07-11 Mitralix Ltd. Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices
US9713530B2 (en) 2008-12-22 2017-07-25 Valtech Cardio, Ltd. Adjustable annuloplasty devices and adjustment mechanisms therefor
US9724192B2 (en) 2011-11-08 2017-08-08 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US9730793B2 (en) 2012-12-06 2017-08-15 Valtech Cardio, Ltd. Techniques for guide-wire based advancement of a tool
US9737400B2 (en) 2010-12-14 2017-08-22 Colibri Heart Valve Llc Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
US9744037B2 (en) 2013-03-15 2017-08-29 California Institute Of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US9744031B2 (en) 2010-05-25 2017-08-29 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US9750606B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750607B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9763780B2 (en) 2011-10-19 2017-09-19 Twelve, Inc. Devices, systems and methods for heart valve replacement
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
USD800908S1 (en) 2016-08-10 2017-10-24 Mitraltech Ltd. Prosthetic valve element
US9839519B2 (en) 2012-02-29 2017-12-12 Valcare, Inc. Percutaneous annuloplasty system with anterior-posterior adjustment
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9883943B2 (en) 2006-12-05 2018-02-06 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US9889002B2 (en) 2001-08-03 2018-02-13 Jenavalve Technology, Inc. Devices useful for implantation at a heart valve

Families Citing this family (291)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK124690D0 (en) 1990-05-18 1990-05-18 Henning Rud Andersen Klapprotes for implantation in the body for replacement of the natural folding and catheter for use in the implantation of such a prosthesis flap
USRE40377E1 (en) 1996-02-23 2008-06-10 Cardiovascular Technologies Llc Means and method of replacing a heart valve in a minimally invasive manner
US8036741B2 (en) 1996-04-30 2011-10-11 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
EP0850607A1 (en) * 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
US6530952B2 (en) 1997-12-29 2003-03-11 The Cleveland Clinic Foundation Bioprosthetic cardiovascular valve system
US6006134A (en) * 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US7452371B2 (en) * 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6896690B1 (en) 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
DE19904975A1 (en) * 1999-02-06 2000-09-14 Impella Cardiotech Ag A device for intravascular cardiac valve surgery
US6790229B1 (en) * 1999-05-25 2004-09-14 Eric Berreklouw Fixing device, in particular for fixing to vascular wall tissue
US7628803B2 (en) 2001-02-05 2009-12-08 Cook Incorporated Implantable vascular device
US8038708B2 (en) * 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US7195641B2 (en) * 1999-11-19 2007-03-27 Advanced Bio Prosthetic Surfaces, Ltd. Valvular prostheses having metal or pseudometallic construction and methods of manufacture
US6458153B1 (en) * 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
CA2840468C (en) * 2000-01-31 2016-07-26 Cook Biotech Incorporated Stent valves and uses of same
DE10010074B4 (en) * 2000-02-28 2005-04-14 Ferrari, Markus, Dr.med. Dr.disc.pol. Device for fastening and anchoring of cardiac valve prostheses
DE10010073B4 (en) * 2000-02-28 2005-12-22 Ferrari, Markus, Dr.med. Dr.disc.pol. Anchor for implantable heart valve prostheses
USRE45130E1 (en) * 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US6454799B1 (en) * 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
EP1401358B1 (en) * 2000-06-30 2016-08-17 Medtronic, Inc. Apparatus for performing a procedure on a cardiac valve
WO2002022054A1 (en) * 2000-09-12 2002-03-21 Gabbay S Valvular prosthesis and method of using same
US6893459B1 (en) * 2000-09-20 2005-05-17 Ample Medical, Inc. Heart valve annulus device and method of using same
US6602288B1 (en) * 2000-10-05 2003-08-05 Edwards Lifesciences Corporation Minimally-invasive annuloplasty repair segment delivery template, system and method of use
FR2815844B1 (en) * 2000-10-31 2003-01-17 Jacques Seguin tubular support in place, percutaneously, a replacement heart valve
WO2002047539A3 (en) 2000-12-15 2002-10-17 Viacor Inc Apparatus and method for replacing aortic valve
US6585761B2 (en) * 2001-03-01 2003-07-01 Syde A. Taheri Prosthetic vein valve and method
US6503272B2 (en) 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US6733525B2 (en) * 2001-03-23 2004-05-11 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of use
US7374571B2 (en) 2001-03-23 2008-05-20 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of manufacture
US6675809B2 (en) 2001-08-27 2004-01-13 Richard S. Stack Satiation devices and methods
US20040117031A1 (en) * 2001-08-27 2004-06-17 Stack Richard S. Satiation devices and methods
US7146984B2 (en) * 2002-04-08 2006-12-12 Synecor, Llc Method and apparatus for modifying the exit orifice of a satiation pouch
CN101810521B (en) 2001-08-27 2015-05-13 辛尼科有限责任公司 Satiation devices and methods
US6845776B2 (en) * 2001-08-27 2005-01-25 Richard S. Stack Satiation devices and methods
US6723122B2 (en) 2001-08-30 2004-04-20 Edwards Lifesciences Corporation Container and method for storing and delivering minimally-invasive heart valves
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
WO2004030568A3 (en) * 2002-10-01 2004-09-30 Ample Medical Inc Device and method for repairing a native heart valve leaflet
US6893460B2 (en) * 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
US6592594B2 (en) 2001-10-25 2003-07-15 Spiration, Inc. Bronchial obstruction device deployment system and method
US6929637B2 (en) 2002-02-21 2005-08-16 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US20030154988A1 (en) * 2002-02-21 2003-08-21 Spiration, Inc. Intra-bronchial device that provides a medicant intra-bronchially to the patient
US20030181922A1 (en) * 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US7125418B2 (en) * 2002-04-16 2006-10-24 The International Heart Institute Of Montana Foundation Sigmoid valve and method for its percutaneous implantation
US20030195385A1 (en) * 2002-04-16 2003-10-16 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US7141064B2 (en) 2002-05-08 2006-11-28 Edwards Lifesciences Corporation Compressed tissue for heart valve leaflets
US20030212412A1 (en) * 2002-05-09 2003-11-13 Spiration, Inc. Intra-bronchial obstructing device that permits mucus transport
US7270675B2 (en) 2002-05-10 2007-09-18 Cordis Corporation Method of forming a tubular membrane on a structural frame
US7485141B2 (en) 2002-05-10 2009-02-03 Cordis Corporation Method of placing a tubular membrane on a structural frame
WO2003094795A1 (en) * 2002-05-10 2003-11-20 Cordis Corporation Method of making a medical device having a thin wall tubular membrane over a structural frame
US7351256B2 (en) 2002-05-10 2008-04-01 Cordis Corporation Frame based unidirectional flow prosthetic implant
US20030216769A1 (en) 2002-05-17 2003-11-20 Dillard David H. Removable anchored lung volume reduction devices and methods
US7241257B1 (en) * 2002-06-28 2007-07-10 Abbott Cardiovascular Systems, Inc. Devices and methods to perform minimally invasive surgeries
US8348963B2 (en) * 2002-07-03 2013-01-08 Hlt, Inc. Leaflet reinforcement for regurgitant valves
EP2517674B1 (en) * 2002-08-15 2016-03-16 Cook Medical Technologies LLC Implantable vascular device
EP1592367B1 (en) * 2002-08-28 2016-04-13 HLT, Inc. Method and device for treating diseased valve
US6875231B2 (en) * 2002-09-11 2005-04-05 3F Therapeutics, Inc. Percutaneously deliverable heart valve
US7137184B2 (en) 2002-09-20 2006-11-21 Edwards Lifesciences Corporation Continuous heart valve support frame and method of manufacture
US20060188331A1 (en) * 2002-09-28 2006-08-24 Moore Orel R Extended life road system and method
FR2847150B1 (en) * 2002-11-15 2005-01-21 Claude Mialhe Occlusive device for medical or surgical destination
US6830585B1 (en) 2003-01-14 2004-12-14 3F Therapeutics, Inc. Percutaneously deliverable heart valve and methods of implantation
US20040143342A1 (en) 2003-01-16 2004-07-22 Stack Richard S. Satiation pouches and methods of use
US7097665B2 (en) 2003-01-16 2006-08-29 Synecor, Llc Positioning tools and methods for implanting medical devices
US7399315B2 (en) * 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US20050107871A1 (en) * 2003-03-30 2005-05-19 Fidel Realyvasquez Apparatus and methods for valve repair
US7100616B2 (en) 2003-04-08 2006-09-05 Spiration, Inc. Bronchoscopic lung volume reduction method
US7658759B2 (en) * 2003-04-24 2010-02-09 Cook Incorporated Intralumenally implantable frames
US6974476B2 (en) 2003-05-05 2005-12-13 Rex Medical, L.P. Percutaneous aortic valve
US7007396B2 (en) * 2003-05-29 2006-03-07 Plc Medical Systems, Inc. Replacement heart valve sizing device
US7537592B2 (en) * 2003-06-20 2009-05-26 Plc Medical Systems, Inc. Endovascular tissue removal device
WO2005002466A3 (en) * 2003-07-08 2005-03-03 Ventor Technologies Ltd Implantable prosthetic devices particularly for transarterial delivery in the treatment of aortic stenosis, and methods of implanting such devices
US7201772B2 (en) * 2003-07-08 2007-04-10 Ventor Technologies, Ltd. Fluid flow prosthetic device
JP4599353B2 (en) 2003-07-17 2010-12-15 コラゾン テクノロジーズ インコーポレーティッド Percutaneously treat apparatus aortic valve stenosis
EP1653888B1 (en) * 2003-07-21 2009-09-09 The Trustees of The University of Pennsylvania Percutaneous heart valve
US7204255B2 (en) * 2003-07-28 2007-04-17 Plc Medical Systems, Inc. Endovascular tissue removal device
DE10334868B4 (en) * 2003-07-29 2013-10-17 Pfm Medical Ag The implantable device as an organ valve replacement, its manufacturing method and the substrate and diaphragm element therefor
WO2005011535A3 (en) * 2003-07-31 2006-03-16 Cook Inc Prosthetic valve for implantation in a body vessel
US7533671B2 (en) 2003-08-08 2009-05-19 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US20050075725A1 (en) 2003-10-02 2005-04-07 Rowe Stanton J. Implantable prosthetic valve with non-laminar flow
EP1684671A4 (en) * 2003-10-06 2010-12-01 3F Therapeutics Inc Minimally invasive valve replacement system
US7604650B2 (en) * 2003-10-06 2009-10-20 3F Therapeutics, Inc. Method and assembly for distal embolic protection
US8206456B2 (en) 2003-10-10 2012-06-26 Barosense, Inc. Restrictive and/or obstructive implant system for inducing weight loss
US20050247320A1 (en) 2003-10-10 2005-11-10 Stack Richard S Devices and methods for retaining a gastro-esophageal implant
US7070616B2 (en) 2003-10-31 2006-07-04 Cordis Corporation Implantable valvular prosthesis
US7347869B2 (en) 2003-10-31 2008-03-25 Cordis Corporation Implantable valvular prosthesis
US7261732B2 (en) 2003-12-22 2007-08-28 Henri Justino Stent mounted valve
US20050137686A1 (en) * 2003-12-23 2005-06-23 Sadra Medical, A Delaware Corporation Externally expandable heart valve anchor and method
US20050137064A1 (en) * 2003-12-23 2005-06-23 Stephen Nothnagle Hand weights with finger support
US8246675B2 (en) * 2003-12-23 2012-08-21 Laboratoires Perouse Kit for implanting in a duct
JP4842144B2 (en) * 2003-12-23 2011-12-21 サドラ・メディカル・インコーポレーテッド Re-deployable heart valves
US7470285B2 (en) * 2004-02-05 2008-12-30 Children's Medical Center Corp. Transcatheter delivery of a replacement heart valve
CA2557657C (en) 2004-02-27 2013-06-18 Aortx, Inc. Prosthetic heart valve delivery systems and methods
US20070073387A1 (en) * 2004-02-27 2007-03-29 Forster David C Prosthetic Heart Valves, Support Structures And Systems And Methods For Implanting The Same
JP2007535342A (en) 2004-03-11 2007-12-06 パーキュテイニアス カルディオバスキュラー ソリューションズ ピー・ティー・ワイ リミテッド Percutaneous prosthetic heart valve
WO2005087139A1 (en) * 2004-03-15 2005-09-22 Baker Medical Research Institute Treating valve failure
US8349001B2 (en) * 2004-04-07 2013-01-08 Medtronic, Inc. Pharmacological delivery implement for use with cardiac repair devices
US20050240200A1 (en) 2004-04-23 2005-10-27 Bjarne Bergheim Method and system for cardiac valve delivery
US7641686B2 (en) 2004-04-23 2010-01-05 Direct Flow Medical, Inc. Percutaneous heart valve with stentless support
WO2005105003A1 (en) 2004-04-26 2005-11-10 Synecor, Llc Restrictive and/or obstructive implant for inducing weight loss
US20060122692A1 (en) * 2004-05-10 2006-06-08 Ran Gilad Stent valve and method of using same
US20060122686A1 (en) * 2004-05-10 2006-06-08 Ran Gilad Stent and method of manufacturing same
US20060122693A1 (en) * 2004-05-10 2006-06-08 Youssef Biadillah Stent valve and method of manufacturing same
US7462191B2 (en) * 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US7276078B2 (en) 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
EP1781179A1 (en) * 2004-07-06 2007-05-09 Baker Medical Research Institute Treating valvular insufficiency
CN1745727A (en) * 2004-09-08 2006-03-15 王蓉珍 Intercurrent artificial heart valve, its implanting and recovering device
CN101056596B (en) 2004-09-14 2011-08-03 爱德华兹生命科学股份公司 Device and method for treatment of heart valve regurgitation
WO2006034436A3 (en) 2004-09-21 2006-10-19 Stout Medical Group Lp Expandable support device and method of use
WO2006041505A1 (en) * 2004-10-02 2006-04-20 Huber Christoph Hans Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support
US7641687B2 (en) * 2004-11-02 2010-01-05 Carbomedics Inc. Attachment of a sewing cuff to a heart valve
US7758640B2 (en) 2004-12-16 2010-07-20 Valvexchange Inc. Cardiovascular valve assembly
DE102005003632A1 (en) 2005-01-20 2006-08-17 Ferrari, Markus, Dr.med. Dr.disc.pol. Catheter for trans-vascular implantation of prosthetic heart valves
DK1850796T3 (en) * 2005-02-18 2016-01-18 Cleveland Clinic Foundation Apparatus for replacement of a heart valve
US20060195186A1 (en) * 2005-02-28 2006-08-31 Drews Michael J Connectors for two piece heart valves and methods for implanting such heart valves
US8083793B2 (en) 2005-02-28 2011-12-27 Medtronic, Inc. Two piece heart valves including multiple lobe valves and methods for implanting them
US7833268B2 (en) * 2005-04-29 2010-11-16 Delgado Iii Reynolds M Method and apparatus for implanting an aortic valve prosthesis
CA2608347A1 (en) * 2005-05-13 2006-11-23 Cook Incorporated Medical device delivery systems that facilitate medical device placement in the presence of ultrasonic waves
US7708775B2 (en) * 2005-05-24 2010-05-04 Edwards Lifesciences Corporation Methods for rapid deployment of prosthetic heart valves
US8663312B2 (en) 2005-05-27 2014-03-04 Hlt, Inc. Intravascular cuff
WO2006128193A3 (en) 2005-05-27 2007-11-22 Heart Leaflet Technologies Inc Stentless support structure
US7780723B2 (en) * 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
WO2007009107A3 (en) 2005-07-14 2008-08-07 Scott E Greenhalgh Expandable support device and method of use
US8790396B2 (en) * 2005-07-27 2014-07-29 Medtronic 3F Therapeutics, Inc. Methods and systems for cardiac valve delivery
US9055942B2 (en) * 2005-10-03 2015-06-16 Boston Scienctific Scimed, Inc. Endoscopic plication devices and methods
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
CA2668988A1 (en) * 2005-12-15 2007-09-07 Georgia Tech Research Corporation Systems and methods for enabling heart valve replacement
CA2669188C (en) 2005-12-15 2014-08-05 Georgia Tech Research Corporation Papillary muscle position control devices, systems, & methods
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
EP2583640A3 (en) 2006-02-16 2013-07-17 Transcatheter Technologies GmbH Minimally invasive heart valve replacement
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8403981B2 (en) 2006-02-27 2013-03-26 CardiacMC, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US7691151B2 (en) 2006-03-31 2010-04-06 Spiration, Inc. Articulable Anchor
US20070239254A1 (en) * 2006-04-07 2007-10-11 Chris Chia System for percutaneous delivery and removal of a prosthetic valve
US8070800B2 (en) * 2006-05-05 2011-12-06 Children's Medical Center Corporation Transcatheter heart valve prostheses
US8932348B2 (en) 2006-05-18 2015-01-13 Edwards Lifesciences Corporation Device and method for improving heart valve function
US8585594B2 (en) * 2006-05-24 2013-11-19 Phoenix Biomedical, Inc. Methods of assessing inner surfaces of body lumens or organs
US20110276127A1 (en) * 2006-05-24 2011-11-10 Forster David C Multiple inflation of an expandable member as a precursor to an implant procedure
CN101484093B (en) 2006-06-01 2011-09-07 爱德华兹生命科学公司 Prosthetic insert for improving heart valve function
EP2298243A1 (en) 2006-06-20 2011-03-23 AorTx, Inc. Prosthetic heart valves, support structures and systems and methods for implanting the same
US8376865B2 (en) 2006-06-20 2013-02-19 Cardiacmd, Inc. Torque shaft and torque shaft drive
US8142492B2 (en) 2006-06-21 2012-03-27 Aortx, Inc. Prosthetic valve implantation systems
WO2008013915A9 (en) * 2006-07-28 2008-08-21 Arshad Quadri Percutaneous valve prosthesis and system and method for implanting same
US9814611B2 (en) 2007-07-31 2017-11-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
EP2068765A4 (en) 2006-07-31 2013-05-01 Cartledge Richard G Sealable endovascular implants and methods for their use
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
EP2572673B1 (en) 2006-09-02 2015-08-19 Boston Scientific Scimed, Inc. Intestinal sleeves and associated deployment systems and methods
CN102247223B (en) * 2006-09-08 2015-05-06 爱德华兹生命科学公司 Integrated heart valve delivery system
WO2008033474A3 (en) 2006-09-15 2008-05-22 Synecor Llc System for anchoring stomach implant
US20090248143A1 (en) * 2006-10-24 2009-10-01 Beth Israel Deaconess Medical Center Percutaneous aortic valve assembly
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
WO2008089365A2 (en) * 2007-01-19 2008-07-24 The Cleveland Clinic Foundation Method for implanting a cardiovascular valve
US8038709B2 (en) 2007-01-30 2011-10-18 Boston Scientific Scimed, Inc. Local delivery of therapeutic agent to heart valves
US20080262593A1 (en) * 2007-02-15 2008-10-23 Ryan Timothy R Multi-layered stents and methods of implanting
US8070802B2 (en) * 2007-02-23 2011-12-06 The Trustees Of The University Of Pennsylvania Mitral valve system
US20080208328A1 (en) * 2007-02-23 2008-08-28 Endovalve, Inc. Systems and Methods For Placement of Valve Prosthesis System
US8556988B2 (en) * 2007-03-15 2013-10-15 Insightra Medical, Inc. Apparatus and repair of defect in inguinal canal and other muscular structures
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
EP3150171A1 (en) 2007-05-15 2017-04-05 JenaValve Technology, Inc. Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandalbe heart valve stent
EP2155115A1 (en) * 2007-04-13 2010-02-24 Jenavalve Technology INC. Medical device for treating a heart valve insufficiency or stenosis
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
CA2696993C (en) 2007-07-18 2017-01-03 Samuel T. Crews Endoscopic implant system and method
US20090030284A1 (en) 2007-07-18 2009-01-29 David Cole Overtube introducer for use in endoscopic bariatric surgery
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
DE102007043830A1 (en) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Heart valve stent
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US20110035018A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with composite component
JP5628673B2 (en) 2007-09-26 2014-11-19 セント ジュード メディカル インコーポレイテッド Foldable artificial heart valve
US8784481B2 (en) 2007-09-28 2014-07-22 St. Jude Medical, Inc. Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features
US9532868B2 (en) 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US8715359B2 (en) * 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
CN101868199B (en) 2007-10-12 2016-04-06 斯波瑞申有限公司 Valve loader methods, systems, and devices
US20090105813A1 (en) * 2007-10-17 2009-04-23 Sean Chambers Implantable valve device
EP2679198A1 (en) 2007-10-25 2014-01-01 Symetis Sa Stents, valved-stents and methods and systems for delivery thereof
US8597349B2 (en) 2007-11-05 2013-12-03 St. Jude Medical, Inc. Collapsible/expandable prosthetic heart valves with non-expanding stent posts and retrieval features
US8715337B2 (en) * 2007-11-09 2014-05-06 Cook Medical Technologies Llc Aortic valve stent graft
EP2231070B1 (en) 2007-12-14 2013-05-22 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US20090171383A1 (en) 2007-12-31 2009-07-02 David Cole Gastric space occupier systems and methods of use
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8465540B2 (en) 2008-02-26 2013-06-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
EP2247264A4 (en) * 2008-02-29 2011-08-31 Florida Int Univ Board Trustees Catheter deliverable artificial multi-leaflet heart valve prosthesis and intravascular delivery system for a catheter deliverable heart valve prosthesis
CA2961051A1 (en) 2008-02-29 2009-09-03 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US8020741B2 (en) 2008-03-18 2011-09-20 Barosense, Inc. Endoscopic stapling devices and methods
US7806919B2 (en) * 2008-04-01 2010-10-05 Medtronic Vascular, Inc. Double-walled stent system
WO2009132187A1 (en) 2008-04-23 2009-10-29 Medtronic, Inc. Stented heart valve devices
US9061119B2 (en) * 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
ES2645920T3 (en) 2008-06-06 2017-12-11 Edwards Lifesciences Corporation Transcatheter heart valve low profile
FR2932376B1 (en) * 2008-06-11 2011-04-01 Perouse Lab Device for treating a blood circulation conduit
US8029557B2 (en) * 2008-06-20 2011-10-04 Vysera Biomedical Limited Esophageal valve
US8323335B2 (en) * 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
ES2584315T3 (en) 2008-07-15 2016-09-27 St. Jude Medical, Inc. Collapsible designs and reexpansible Prosthetic heart valve sleeve and complementary technological applications
US20110208299A1 (en) 2008-08-19 2011-08-25 Roelof Marissen Implantable valve prosthesis and method for manufacturing such a valve
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
CA2736817A1 (en) 2008-09-12 2010-03-18 Valvexchange Inc. Valve assembly with exchangeable valve member and a tool set for exchanging the valve member
US9314335B2 (en) 2008-09-19 2016-04-19 Edwards Lifesciences Corporation Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation
CN102292053A (en) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 Heart valve
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
WO2010040009A1 (en) 2008-10-01 2010-04-08 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8690936B2 (en) 2008-10-10 2014-04-08 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
US7934631B2 (en) 2008-11-10 2011-05-03 Barosense, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
WO2010067463A1 (en) * 2008-12-10 2010-06-17 株式会社カルディオ Instrument for capturing tissue piece to be used in aortic valve replacement surgery and method of capturing tissue piece in aortic valve replacement surgery
US8998982B2 (en) 2009-01-12 2015-04-07 Valve Medical Ltd. Method and apparatus for fine adjustment of a percutaneous valve structure
US20100210899A1 (en) * 2009-01-21 2010-08-19 Tendyne Medical, Inc. Method for percutaneous lateral access to the left ventricle for treatment of mitral insufficiency by papillary muscle alignment
US20100217382A1 (en) * 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
US20110015476A1 (en) * 2009-03-04 2011-01-20 Jeff Franco Devices and Methods for Treating Cardiomyopathy
US7967138B2 (en) 2009-04-06 2011-06-28 Medtronic Vascular, Inc. Packaging systems for percutaneously deliverable bioprosthetic valves
US20100261662A1 (en) * 2009-04-09 2010-10-14 Endologix, Inc. Utilization of mural thrombus for local drug delivery into vascular tissue
EP2419050B1 (en) * 2009-04-15 2017-06-28 Edwards Lifesciences CardiAQ LLC Vascular implant and delivery system
US8500801B2 (en) * 2009-04-21 2013-08-06 Medtronic, Inc. Stents for prosthetic heart valves and methods of making same
EP2243443A1 (en) * 2009-04-22 2010-10-27 den Berg Cornelis Johannes Maria Van A stent comprising a tricuspid valve
US8961539B2 (en) 2009-05-04 2015-02-24 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US8468667B2 (en) 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
US8075611B2 (en) * 2009-06-02 2011-12-13 Medtronic, Inc. Stented prosthetic heart valves
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US8475522B2 (en) 2009-07-14 2013-07-02 Edwards Lifesciences Corporation Transapical delivery system for heart valves
JP5906553B2 (en) * 2009-08-28 2016-04-20 メドトロニック 3エフ セラピュティックス インコーポレイテッド Surgical conveying apparatus and method of use
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9072603B2 (en) * 2010-02-24 2015-07-07 Medtronic Ventor Technologies, Ltd. Mitral prosthesis and methods for implantation
EP2542186A4 (en) * 2010-03-05 2016-01-13 Edwards Lifesciences Corp Retaining mechanisms for prosthetic valves
US8795354B2 (en) * 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
US8992599B2 (en) * 2010-03-26 2015-03-31 Thubrikar Aortic Valve, Inc. Valve component, frame component and prosthetic valve device including the same for implantation in a body lumen
CN101961269B (en) * 2010-04-19 2012-09-05 杭州启明医疗器械有限公司 Conveying device for conveying artificial cardiac valve replacement device
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
WO2011143263A3 (en) 2010-05-10 2013-01-24 Heart Leaflet Technologies, Inc. Stentless support structure
US8535380B2 (en) 2010-05-13 2013-09-17 Stout Medical Group, L.P. Fixation device and method
US9603708B2 (en) 2010-05-19 2017-03-28 Dfm, Llc Low crossing profile delivery catheter for cardiovascular prosthetic implant
US20110288626A1 (en) 2010-05-20 2011-11-24 Helmut Straubinger Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9308086B2 (en) 2010-09-21 2016-04-12 Hocor Cardiovascular Technologies Llc Method and system for balloon counterpulsation during aortic valve replacement
EP3001978A1 (en) 2010-09-23 2016-04-06 CardiAQ Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
CA2813419A1 (en) 2010-10-05 2012-04-12 Edwards Lifesciences Corporation Prosthetic heart valve
US9149286B1 (en) 2010-11-12 2015-10-06 Flexmedex, LLC Guidance tool and method for use
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
WO2012127309A4 (en) 2011-03-21 2013-01-31 Montorfano Matteo Disk-based valve apparatus and method for the treatment of valve dysfunction
US9381082B2 (en) 2011-04-22 2016-07-05 Edwards Lifesciences Corporation Devices, systems and methods for accurate positioning of a prosthetic valve
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
EP2747682A4 (en) 2011-08-23 2015-01-21 Flexmedex Llc Tissue removal device and method
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9445897B2 (en) * 2012-05-01 2016-09-20 Direct Flow Medical, Inc. Prosthetic implant delivery device with introducer catheter
US20140005776A1 (en) 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
US20140336690A1 (en) * 2012-07-06 2014-11-13 Michael Zhadkevich Occluding Catheter and Dynamic Method for Prevention of Stroke
ES2647580T3 (en) * 2012-07-12 2017-12-22 Boston Scientific Scimed, Inc. Delivery system heart valve low profile
WO2014021905A1 (en) 2012-07-30 2014-02-06 Tendyne Holdings, Inc. Improved delivery systems and methods for transcatheter prosthetic valves
EP2695586A1 (en) 2012-08-10 2014-02-12 Sorin Group Italia S.r.l. A valve prosthesis and kit
CN102805676B (en) 2012-08-14 2015-06-17 杭州启明医疗器械有限公司 Compression device for artificial valve replacement device
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
EP2732796A1 (en) * 2012-11-20 2014-05-21 Nakostech Sarl Mitral valve replacement system
EP2922592A4 (en) * 2012-11-21 2016-10-19 Edwards Lifesciences Corp Retaining mechanisms for prosthetic heart valves
US9375310B2 (en) 2012-12-31 2016-06-28 Edwards Lifesciences Corporation Surgical heart valves adapted for post-implant expansion
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
JP2016506821A (en) * 2013-02-08 2016-03-07 マフィン・インコーポレイテッドMuffin Incorporated Periphery sealed vein check valve
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9119713B2 (en) * 2013-03-11 2015-09-01 St. Jude Medical, Cardiology Division, Inc. Transcatheter valve replacement
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
CN105208973A (en) 2013-03-15 2015-12-30 Hlt股份有限公司 Low-profile prosthetic valve structure
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
CN107334563A (en) 2013-05-20 2017-11-10 爱德华兹生命科学公司 Artificial heart valve delivery devices
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
CN105658178A (en) 2013-06-25 2016-06-08 坦迪尼控股股份有限公司 Thrombus management and structural compliance features for prosthetic heart valves
WO2015002832A1 (en) * 2013-07-01 2015-01-08 St. Jude Medical, Cardiology Division, Inc. Hybrid orientation pravalvular sealing stent
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
WO2015013666A8 (en) 2013-07-26 2015-03-19 Cardiaq Valve Technologies, Inc. Systems and methods for sealing openings in an anatomical wall
US20150119974A1 (en) * 2013-10-24 2015-04-30 Medtronic, Inc. Modular valve prosthesis with anchor stent and valve component
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9700409B2 (en) * 2013-11-06 2017-07-11 St. Jude Medical, Cardiology Division, Inc. Reduced profile prosthetic heart valve
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US9072604B1 (en) * 2014-02-11 2015-07-07 Gilberto Melnick Modular transcatheter heart valve and implantation method
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US20160158000A1 (en) 2014-12-09 2016-06-09 Juan F. Granada Replacement cardiac valves and methods of use and manufacture
US20170128203A1 (en) * 2015-11-06 2017-05-11 Micor Limited Mitral valve prosthesis
US20170165065A1 (en) * 2015-12-14 2017-06-15 Medtronic, Inc. Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis

Citations (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409013A (en) * 1965-08-23 1968-11-05 Berry Henry Instrument for inserting artificial heart valves
US3587115A (en) * 1966-05-04 1971-06-28 Donald P Shiley Prosthetic sutureless heart valves and implant tools therefor
US3657744A (en) * 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3671979A (en) * 1969-09-23 1972-06-27 Univ Utah Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve
US3714671A (en) * 1970-11-30 1973-02-06 Cutter Lab Tissue-type heart valve with a graft support ring or stent
US3755823A (en) * 1971-04-23 1973-09-04 Hancock Laboratories Inc Flexible stent for heart valve
US4035849A (en) * 1975-11-17 1977-07-19 William W. Angell Heart valve stent and process for preparing a stented heart valve prosthesis
US4038703A (en) * 1975-11-14 1977-08-02 General Atomic Company Prosthetic devices having a region of controlled porosity
US4056854A (en) * 1976-09-28 1977-11-08 The United States Of America As Represented By The Department Of Health, Education And Welfare Aortic heart valve catheter
US4106129A (en) * 1976-01-09 1978-08-15 American Hospital Supply Corporation Supported bioprosthetic heart valve with compliant orifice ring
US4222126A (en) * 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4297749A (en) * 1977-04-25 1981-11-03 Albany International Corp. Heart valve prosthesis
US4339831A (en) * 1981-03-27 1982-07-20 Medtronic, Inc. Dynamic annulus heart valve and reconstruction ring
US4343048A (en) * 1979-08-06 1982-08-10 Ross Donald N Stent for a cardiac valve
US4470157A (en) * 1981-04-27 1984-09-11 Love Jack W Tricuspid prosthetic tissue heart valve
US4574803A (en) * 1979-01-19 1986-03-11 Karl Storz Tissue cutter
US4580568A (en) * 1984-10-01 1986-04-08 Cook, Incorporated Percutaneous endovascular stent and method for insertion thereof
US4592340A (en) * 1984-05-02 1986-06-03 Boyles Paul W Artificial catheter means
US4612011A (en) * 1983-07-22 1986-09-16 Hans Kautzky Central occluder semi-biological heart valve
US4631052A (en) * 1984-01-03 1986-12-23 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
US4655771A (en) * 1982-04-30 1987-04-07 Shepherd Patents S.A. Prosthesis comprising an expansible or contractile tubular body
US4733665A (en) * 1985-11-07 1988-03-29 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4777951A (en) * 1986-09-19 1988-10-18 Mansfield Scientific, Inc. Procedure and catheter instrument for treating patients for aortic stenosis
US4787899A (en) * 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US4787901A (en) * 1984-07-17 1988-11-29 Doguhan Baykut Two-way acting valve and cardiac valve prosthesis
US4796629A (en) * 1987-06-03 1989-01-10 Joseph Grayzel Stiffened dilation balloon catheter device
US4856516A (en) * 1989-01-09 1989-08-15 Cordis Corporation Endovascular stent apparatus and method
US4878495A (en) * 1987-05-15 1989-11-07 Joseph Grayzel Valvuloplasty device with satellite expansion means
US4878906A (en) * 1986-03-25 1989-11-07 Servetus Partnership Endoprosthesis for repairing a damaged vessel
US4883458A (en) * 1987-02-24 1989-11-28 Surgical Systems & Instruments, Inc. Atherectomy system and method of using the same
USRE33258E (en) * 1984-07-23 1990-07-10 Surgical Dynamics Inc. Irrigating, cutting and aspirating system for percutaneous surgery
US4966604A (en) * 1989-01-23 1990-10-30 Interventional Technologies Inc. Expandable atherectomy cutter with flexibly bowed blades
US4979939A (en) * 1984-05-14 1990-12-25 Surgical Systems & Instruments, Inc. Atherectomy system with a guide wire
US4986830A (en) * 1989-09-22 1991-01-22 Schneider (U.S.A.) Inc. Valvuloplasty catheter with balloon which remains stable during inflation
US4994077A (en) * 1989-04-21 1991-02-19 Dobben Richard L Artificial heart valve for implantation in a blood vessel
US5000743A (en) * 1987-02-27 1991-03-19 Patel Piyush V Catheter assembly and method of performing percutaneous transluminal coronary angioplasty
US5007896A (en) * 1988-12-19 1991-04-16 Surgical Systems & Instruments, Inc. Rotary-catheter for atherectomy
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US5026366A (en) * 1984-03-01 1991-06-25 Cardiovascular Laser Systems, Inc. Angioplasty catheter and method of use thereof
US5032128A (en) * 1988-07-07 1991-07-16 Medtronic, Inc. Heart valve prosthesis
US5037434A (en) * 1990-04-11 1991-08-06 Carbomedics, Inc. Bioprosthetic heart valve with elastic commissures
US5047041A (en) * 1989-08-22 1991-09-10 Samuels Peter B Surgical apparatus for the excision of vein valves in situ
US5053008A (en) * 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5059177A (en) * 1990-04-19 1991-10-22 Cordis Corporation Triple lumen balloon catheter
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5084010A (en) * 1990-02-20 1992-01-28 Devices For Vascular Intervention, Inc. System and method for catheter construction
US5085835A (en) * 1988-10-01 1992-02-04 Hoechst Aktiengesellschaft Process for recovering rhodium
US5089015A (en) * 1989-11-28 1992-02-18 Promedica International Method for implanting unstented xenografts and allografts
US5152771A (en) * 1990-12-31 1992-10-06 The Board Of Supervisors Of Louisiana State University Valve cutter for arterial by-pass surgery
US5160342A (en) * 1990-08-16 1992-11-03 Evi Corp. Endovascular filter and method for use thereof
US5163953A (en) * 1992-02-10 1992-11-17 Vince Dennis J Toroidal artificial heart valve stent
US5167626A (en) * 1990-10-02 1992-12-01 Glaxo Inc. Medical capsule device actuated by radio-frequency (RF) signal
US5295958A (en) * 1991-04-04 1994-03-22 Shturman Cardiology Systems, Inc. Method and apparatus for in vivo heart valve decalcification
US5332402A (en) * 1992-05-12 1994-07-26 Teitelbaum George P Percutaneously-inserted cardiac valve
US5358518A (en) * 1991-06-25 1994-10-25 Sante Camilli Artificial venous valve
US5397351A (en) * 1991-05-13 1995-03-14 Pavcnik; Dusan Prosthetic valve for percutaneous insertion
US5411552A (en) * 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5480424A (en) * 1993-11-01 1996-01-02 Cox; James L. Heart valve replacement using flexible tubes
US5500014A (en) * 1989-05-31 1996-03-19 Baxter International Inc. Biological valvular prothesis
US5545209A (en) * 1993-09-30 1996-08-13 Texas Petrodet, Inc. Controlled deployment of a medical device
US5593405A (en) * 1994-07-16 1997-01-14 Osypka; Peter Fiber optic endoscope
US5840081A (en) * 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US5853419A (en) * 1997-03-17 1998-12-29 Surface Genesis, Inc. Stent
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863366A (en) 1995-06-07 1999-01-26 Heartport, Inc. Method of manufacture of a cannula for a medical device
US5370685A (en) 1991-07-16 1994-12-06 Stanford Surgical Technologies, Inc. Endovascular aortic valve replacement
US5254097A (en) 1992-01-06 1993-10-19 Datascope Investment Corp. Combined percutaneous cardiopulmonary bypass (PBY) and intra-aortic balloon (IAB) access cannula
US5718725A (en) 1992-12-03 1998-02-17 Heartport, Inc. Devices and methods for intracardiac procedures
US5413549A (en) 1993-10-07 1995-05-09 Datascope Investment Corp. Devices and methods for efficient intra-aortic balloon pumping
EP0850607A1 (en) * 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
US5817001A (en) 1997-05-27 1998-10-06 Datascope Investment Corp. Method and apparatus for driving an intra-aortic balloon pump

Patent Citations (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409013A (en) * 1965-08-23 1968-11-05 Berry Henry Instrument for inserting artificial heart valves
US3587115A (en) * 1966-05-04 1971-06-28 Donald P Shiley Prosthetic sutureless heart valves and implant tools therefor
US3671979A (en) * 1969-09-23 1972-06-27 Univ Utah Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve
US3657744A (en) * 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3714671A (en) * 1970-11-30 1973-02-06 Cutter Lab Tissue-type heart valve with a graft support ring or stent
US3755823A (en) * 1971-04-23 1973-09-04 Hancock Laboratories Inc Flexible stent for heart valve
US4038703A (en) * 1975-11-14 1977-08-02 General Atomic Company Prosthetic devices having a region of controlled porosity
US4035849A (en) * 1975-11-17 1977-07-19 William W. Angell Heart valve stent and process for preparing a stented heart valve prosthesis
US4106129A (en) * 1976-01-09 1978-08-15 American Hospital Supply Corporation Supported bioprosthetic heart valve with compliant orifice ring
US4056854A (en) * 1976-09-28 1977-11-08 The United States Of America As Represented By The Department Of Health, Education And Welfare Aortic heart valve catheter
US4297749A (en) * 1977-04-25 1981-11-03 Albany International Corp. Heart valve prosthesis
US4222126A (en) * 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4574803A (en) * 1979-01-19 1986-03-11 Karl Storz Tissue cutter
US4343048A (en) * 1979-08-06 1982-08-10 Ross Donald N Stent for a cardiac valve
US4339831A (en) * 1981-03-27 1982-07-20 Medtronic, Inc. Dynamic annulus heart valve and reconstruction ring
US4470157A (en) * 1981-04-27 1984-09-11 Love Jack W Tricuspid prosthetic tissue heart valve
US4655771A (en) * 1982-04-30 1987-04-07 Shepherd Patents S.A. Prosthesis comprising an expansible or contractile tubular body
US4655771B1 (en) * 1982-04-30 1996-09-10 Medinvent Ams Sa Prosthesis comprising an expansible or contractile tubular body
US4612011A (en) * 1983-07-22 1986-09-16 Hans Kautzky Central occluder semi-biological heart valve
US4787899A (en) * 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US4631052A (en) * 1984-01-03 1986-12-23 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
US5026366A (en) * 1984-03-01 1991-06-25 Cardiovascular Laser Systems, Inc. Angioplasty catheter and method of use thereof
US4592340A (en) * 1984-05-02 1986-06-03 Boyles Paul W Artificial catheter means
US4979939A (en) * 1984-05-14 1990-12-25 Surgical Systems & Instruments, Inc. Atherectomy system with a guide wire
US4787901A (en) * 1984-07-17 1988-11-29 Doguhan Baykut Two-way acting valve and cardiac valve prosthesis
USRE33258E (en) * 1984-07-23 1990-07-10 Surgical Dynamics Inc. Irrigating, cutting and aspirating system for percutaneous surgery
US4580568A (en) * 1984-10-01 1986-04-08 Cook, Incorporated Percutaneous endovascular stent and method for insertion thereof
US4733665B1 (en) * 1985-11-07 1994-01-11 Expandable Grafts Partnership Expandable intraluminal graft,and method and apparatus for implanting an expandable intraluminal graft
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4733665A (en) * 1985-11-07 1988-03-29 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4878906A (en) * 1986-03-25 1989-11-07 Servetus Partnership Endoprosthesis for repairing a damaged vessel
US4777951A (en) * 1986-09-19 1988-10-18 Mansfield Scientific, Inc. Procedure and catheter instrument for treating patients for aortic stenosis
US4883458A (en) * 1987-02-24 1989-11-28 Surgical Systems & Instruments, Inc. Atherectomy system and method of using the same
US5000743A (en) * 1987-02-27 1991-03-19 Patel Piyush V Catheter assembly and method of performing percutaneous transluminal coronary angioplasty
US4878495A (en) * 1987-05-15 1989-11-07 Joseph Grayzel Valvuloplasty device with satellite expansion means
US4796629A (en) * 1987-06-03 1989-01-10 Joseph Grayzel Stiffened dilation balloon catheter device
US5032128A (en) * 1988-07-07 1991-07-16 Medtronic, Inc. Heart valve prosthesis
US5085835A (en) * 1988-10-01 1992-02-04 Hoechst Aktiengesellschaft Process for recovering rhodium
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US5007896A (en) * 1988-12-19 1991-04-16 Surgical Systems & Instruments, Inc. Rotary-catheter for atherectomy
US4856516A (en) * 1989-01-09 1989-08-15 Cordis Corporation Endovascular stent apparatus and method
US4966604A (en) * 1989-01-23 1990-10-30 Interventional Technologies Inc. Expandable atherectomy cutter with flexibly bowed blades
US4994077A (en) * 1989-04-21 1991-02-19 Dobben Richard L Artificial heart valve for implantation in a blood vessel
US5500014A (en) * 1989-05-31 1996-03-19 Baxter International Inc. Biological valvular prothesis
US5047041A (en) * 1989-08-22 1991-09-10 Samuels Peter B Surgical apparatus for the excision of vein valves in situ
US4986830A (en) * 1989-09-22 1991-01-22 Schneider (U.S.A.) Inc. Valvuloplasty catheter with balloon which remains stable during inflation
US5089015A (en) * 1989-11-28 1992-02-18 Promedica International Method for implanting unstented xenografts and allografts
US5084010A (en) * 1990-02-20 1992-01-28 Devices For Vascular Intervention, Inc. System and method for catheter construction
US5037434A (en) * 1990-04-11 1991-08-06 Carbomedics, Inc. Bioprosthetic heart valve with elastic commissures
US5059177A (en) * 1990-04-19 1991-10-22 Cordis Corporation Triple lumen balloon catheter
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5840081A (en) * 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US5411552A (en) * 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5160342A (en) * 1990-08-16 1992-11-03 Evi Corp. Endovascular filter and method for use thereof
US5167626A (en) * 1990-10-02 1992-12-01 Glaxo Inc. Medical capsule device actuated by radio-frequency (RF) signal
US5053008A (en) * 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5152771A (en) * 1990-12-31 1992-10-06 The Board Of Supervisors Of Louisiana State University Valve cutter for arterial by-pass surgery
US5295958A (en) * 1991-04-04 1994-03-22 Shturman Cardiology Systems, Inc. Method and apparatus for in vivo heart valve decalcification
US5443446A (en) * 1991-04-04 1995-08-22 Shturman Cardiology Systems, Inc. Method and apparatus for in vivo heart valve decalcification
US5397351A (en) * 1991-05-13 1995-03-14 Pavcnik; Dusan Prosthetic valve for percutaneous insertion
US5358518A (en) * 1991-06-25 1994-10-25 Sante Camilli Artificial venous valve
US5163953A (en) * 1992-02-10 1992-11-17 Vince Dennis J Toroidal artificial heart valve stent
US5332402A (en) * 1992-05-12 1994-07-26 Teitelbaum George P Percutaneously-inserted cardiac valve
US5545209A (en) * 1993-09-30 1996-08-13 Texas Petrodet, Inc. Controlled deployment of a medical device
US5480424A (en) * 1993-11-01 1996-01-02 Cox; James L. Heart valve replacement using flexible tubes
US5593405A (en) * 1994-07-16 1997-01-14 Osypka; Peter Fiber optic endoscope
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US5853419A (en) * 1997-03-17 1998-12-29 Surface Genesis, Inc. Stent

Cited By (450)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603159B2 (en) 1999-11-17 2013-12-10 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8986329B2 (en) 1999-11-17 2015-03-24 Medtronic Corevalve Llc Methods for transluminal delivery of prosthetic valves
US8801779B2 (en) 1999-11-17 2014-08-12 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
USRE45865E1 (en) 1999-11-17 2016-01-26 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8579966B2 (en) * 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9060856B2 (en) 1999-11-17 2015-06-23 Medtronic Corevalve Llc Transcatheter heart valves
US20060129235A1 (en) * 1999-11-17 2006-06-15 Jacques Seguin Prosthetic valve for transluminal delivery
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7329278B2 (en) 1999-11-17 2008-02-12 Corevalve, Inc. Prosthetic valve for transluminal delivery
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8998979B2 (en) 1999-11-17 2015-04-07 Medtronic Corevalve Llc Transcatheter heart valves
US8721708B2 (en) 1999-11-17 2014-05-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US9439762B2 (en) 2000-06-01 2016-09-13 Edwards Lifesciences Corporation Methods of implant of a heart valve with a convertible sewing ring
US8777980B2 (en) 2000-06-30 2014-07-15 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8092487B2 (en) 2000-06-30 2012-01-10 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7819915B2 (en) 2000-07-27 2010-10-26 Edwards Lifesciences Corporation Heart valve holders and handling clips therefor
US20080065206A1 (en) * 2000-09-07 2008-03-13 Liddicoat John R Fixation band for affixing a prosthetic heart valve to tissue
US8105377B2 (en) 2000-09-07 2012-01-31 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7771469B2 (en) 2000-09-07 2010-08-10 Medtronic, Inc. Method for implantation of fixation band and prosthetic heart valve to tissue
US7776053B2 (en) 2000-10-26 2010-08-17 Boston Scientific Scimed, Inc. Implantable valve system
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8956402B2 (en) 2001-06-29 2015-02-17 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8070801B2 (en) 2001-06-29 2011-12-06 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US8002826B2 (en) 2001-07-04 2011-08-23 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US8628570B2 (en) 2001-07-04 2014-01-14 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US7682390B2 (en) 2001-07-31 2010-03-23 Medtronic, Inc. Assembly for setting a valve prosthesis in a corporeal duct
US9889002B2 (en) 2001-08-03 2018-02-13 Jenavalve Technology, Inc. Devices useful for implantation at a heart valve
US8585756B2 (en) 2001-08-03 2013-11-19 Jenavalve Technology, Inc. Methods of treating valves
US8579965B2 (en) 2001-08-03 2013-11-12 Jenavalve Technology, Inc. Methods of implanting an implantation device
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7972377B2 (en) 2001-12-27 2011-07-05 Medtronic, Inc. Bioprosthetic heart valve
US9610158B2 (en) 2002-01-04 2017-04-04 Colibri Heart Valve Llc Percutaneously implantable replacement heart valve device and method of making same
US8790398B2 (en) 2002-01-04 2014-07-29 Colibri Heart Valve Llc Percutaneously implantable replacement heart valve device and method of making same
US9186248B2 (en) 2002-01-04 2015-11-17 Colibri Heart Valve Llc Percutaneously implantable replacement heart valve device and method of making same
US9125739B2 (en) 2002-01-04 2015-09-08 Colibri Heart Valve Llc Percutaneous replacement heart valve and a delivery and implantation system
US8900294B2 (en) 2002-01-04 2014-12-02 Colibri Heart Valve Llc Method of controlled release of a percutaneous replacement heart valve
US9554898B2 (en) 2002-01-04 2017-01-31 Colibri Heart Valve Llc Percutaneous prosthetic heart valve
US7682385B2 (en) 2002-04-03 2010-03-23 Boston Scientific Corporation Artificial valve
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US7959674B2 (en) 2002-07-16 2011-06-14 Medtronic, Inc. Suture locking assembly and method of use
US8349003B2 (en) 2002-07-16 2013-01-08 Medtronic, Inc. Suture locking assembly and method of use
US7578843B2 (en) 2002-07-16 2009-08-25 Medtronic, Inc. Heart valve prosthesis
US8460373B2 (en) 2002-12-20 2013-06-11 Medtronic, Inc. Method for implanting a heart valve within an annulus of a patient
US8623080B2 (en) 2002-12-20 2014-01-07 Medtronic, Inc. Biologically implantable prosthesis and methods of using the same
US8551162B2 (en) 2002-12-20 2013-10-08 Medtronic, Inc. Biologically implantable prosthesis
US8025695B2 (en) 2002-12-20 2011-09-27 Medtronic, Inc. Biologically implantable heart valve system
US7981153B2 (en) 2002-12-20 2011-07-19 Medtronic, Inc. Biologically implantable prosthesis methods of using
US9333078B2 (en) 2002-12-20 2016-05-10 Medtronic, Inc. Heart valve assemblies
US7780627B2 (en) 2002-12-30 2010-08-24 Boston Scientific Scimed, Inc. Valve treatment catheter and methods
US6989027B2 (en) 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US20060282161A1 (en) * 2003-06-20 2006-12-14 Medtronic Vascular, Inc. Valve annulus reduction system
US8747463B2 (en) 2003-08-22 2014-06-10 Medtronic, Inc. Methods of using a prosthesis fixturing device
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US20060259137A1 (en) * 2003-10-06 2006-11-16 Jason Artof Minimally invasive valve replacement system
US20050075717A1 (en) * 2003-10-06 2005-04-07 Nguyen Tuoc Tan Minimally invasive valve replacement system
US8603161B2 (en) 2003-10-08 2013-12-10 Medtronic, Inc. Attachment device and methods of using the same
US20070010878A1 (en) * 2003-11-12 2007-01-11 Medtronic Vascular, Inc. Coronary sinus approach for repair of mitral valve regurgitation
US7955384B2 (en) * 2003-11-12 2011-06-07 Medtronic Vascular, Inc. Coronary sinus approach for repair of mitral valve regurgitation
US20050177182A1 (en) * 2003-12-04 2005-08-11 Van Der Burg Erik J. System and method for delivering a left atrial appendage containment device
US9301843B2 (en) 2003-12-19 2016-04-05 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
EP2745805A1 (en) 2003-12-23 2014-06-25 Sadra Medical, Inc. Repositionable heart valve
US9308085B2 (en) 2003-12-23 2016-04-12 Boston Scientific Scimed, Inc. Repositionable heart valve and method
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US9320599B2 (en) 2003-12-23 2016-04-26 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7959672B2 (en) 2003-12-23 2011-06-14 Sadra Medical Replacement valve and anchor
US7988724B2 (en) 2003-12-23 2011-08-02 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
EP2526899A1 (en) 2003-12-23 2012-11-28 Sadra Medical, Inc. Repositionable heart valve
EP2985006A1 (en) 2003-12-23 2016-02-17 Boston Scientific Scimed, Inc. Repositionable heart valve
EP2926767B1 (en) 2003-12-23 2016-05-04 Boston Scientific Scimed, Inc. Repositionable heart valve
EP3020365A1 (en) 2003-12-23 2016-05-18 Boston Scientific Scimed, Inc. Repositionable heart valve
US9358110B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US8623078B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Replacement valve and anchor
US9387076B2 (en) 2003-12-23 2016-07-12 Boston Scientific Scimed Inc. Medical devices and delivery systems for delivering medical devices
US8048153B2 (en) 2003-12-23 2011-11-01 Sadra Medical, Inc. Low profile heart valve and delivery system
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
EP2926766A1 (en) 2003-12-23 2015-10-07 Boston Scientific Scimed, Inc. Repositionable heart valve
EP2926767A1 (en) 2003-12-23 2015-10-07 Boston Scientific Scimed, Inc. Repositionable heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US7824442B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
EP2529697A1 (en) 2003-12-23 2012-12-05 Sadra Medical, Inc. Repositionable heart valve
EP2529699A1 (en) 2003-12-23 2012-12-05 Sadra Medical, Inc. Repositionable heart valve
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9532872B2 (en) 2003-12-23 2017-01-03 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US7748389B2 (en) 2003-12-23 2010-07-06 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
EP2529696A1 (en) 2003-12-23 2012-12-05 Sadra Medical, Inc. Repositionable heart valve
US9585749B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Replacement heart valve assembly
EP2529698A1 (en) 2003-12-23 2012-12-05 Sadra Medical, Inc. Repositionable heart valve
EP2537487A1 (en) 2003-12-23 2012-12-26 Sadra Medical, Inc. Repositionable heart valve
US9585750B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
EP2526895A1 (en) 2003-12-23 2012-11-28 Sadra Medical, Inc. Repositionable heart valve
US8951299B2 (en) 2003-12-23 2015-02-10 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
EP2526898A1 (en) 2003-12-23 2012-11-28 Sadra Medical, Inc. Repositionable heart valve
US9861476B2 (en) 2003-12-23 2018-01-09 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US9872768B2 (en) 2003-12-23 2018-01-23 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
EP2749254A1 (en) 2003-12-23 2014-07-02 Sadra Medical, Inc. Repositionable heart valve
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
WO2005062980A2 (en) 2003-12-23 2005-07-14 Sadra Medical, Inc. Repositionable heart valve
US9393113B2 (en) 2003-12-23 2016-07-19 Boston Scientific Scimed Inc. Retrievable heart valve anchor and method
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US20140243967A1 (en) * 2003-12-23 2014-08-28 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US9155617B2 (en) 2004-01-23 2015-10-13 Edwards Lifesciences Corporation Prosthetic mitral valve
US9730794B2 (en) 2004-01-23 2017-08-15 Edwards Lifesciences Corporation Prosthetic mitral valve
US20130325112A1 (en) * 2004-03-03 2013-12-05 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US20050197695A1 (en) * 2004-03-03 2005-09-08 Sorin Biomedica Cardio S.R.L. Minimally-invasive cardiac-valve prosthesis
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US9867695B2 (en) * 2004-03-03 2018-01-16 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US8535373B2 (en) 2004-03-03 2013-09-17 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US8216299B2 (en) 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US7534259B2 (en) 2004-05-05 2009-05-19 Direct Flow Medical, Inc. Nonstented heart valves with formed in situ support
US7556645B2 (en) 2004-05-05 2009-07-07 Direct Flow Medical, Inc. Translumenally implantable heart valve with formed in place support
US7658762B2 (en) 2004-05-05 2010-02-09 Direct Flow Medical, Inc. Nonstented temporary valve for cardiovascular therapy
US7435257B2 (en) 2004-05-05 2008-10-14 Direct Flow Medical, Inc. Methods of cardiac valve replacement using nonstented prosthetic valve
US9510941B2 (en) 2004-05-05 2016-12-06 Direct Flow Medical, Inc. Method of treating a patient using a retrievable transcatheter prosthetic heart valve
US7320704B2 (en) 2004-05-05 2008-01-22 Direct Flow Medical, Inc. Nonstented temporary valve for cardiovascular therapy
US8012201B2 (en) 2004-05-05 2011-09-06 Direct Flow Medical, Inc. Translumenally implantable heart valve with multiple chamber formed in place support
US20060025854A1 (en) * 2004-05-05 2006-02-02 Lashinski Randall T Translumenally implantable heart valve with formed in place support
US20060020334A1 (en) * 2004-05-05 2006-01-26 Lashinski Randall T Methods of cardiac valve replacement using nonstented prosthetic valve
US8377118B2 (en) 2004-05-05 2013-02-19 Direct Flow Medical, Inc. Unstented heart valve with formed in place support structure
US8308796B2 (en) 2004-05-05 2012-11-13 Direct Flow Medical, Inc. Method of in situ formation of translumenally deployable heart valve support
US7445630B2 (en) 2004-05-05 2008-11-04 Direct Flow Medical, Inc. Method of in situ formation of translumenally deployable heart valve support
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US9744035B2 (en) 2004-06-16 2017-08-29 Boston Scientific Scimed, Inc. Everting heart valve
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US8932349B2 (en) 2004-09-02 2015-01-13 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US8002824B2 (en) 2004-09-02 2011-08-23 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US20120046740A1 (en) * 2004-11-05 2012-02-23 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8617236B2 (en) * 2004-11-05 2013-12-31 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9622859B2 (en) 2005-02-01 2017-04-18 Boston Scientific Scimed, Inc. Filter system and method
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7857845B2 (en) 2005-02-10 2010-12-28 Sorin Biomedica Cardio S.R.L. Cardiac-valve prosthesis
US8540768B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8920492B2 (en) 2005-02-10 2014-12-30 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8574257B2 (en) 2005-02-10 2013-11-05 Edwards Lifesciences Corporation System, device, and method for providing access in a cardiovascular environment
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US9486313B2 (en) 2005-02-10 2016-11-08 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9808341B2 (en) 2005-02-23 2017-11-07 Boston Scientific Scimed Inc. Valve apparatus, system and method
US9370419B2 (en) 2005-02-23 2016-06-21 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9526613B2 (en) 2005-03-17 2016-12-27 Valtech Cardio Ltd. Mitral valve treatment techniques
US9408693B2 (en) 2005-04-05 2016-08-09 Cormove Kit which is intended to be implanted in a blood vessel, and associated tubular endoprosthesis
US20090012600A1 (en) * 2005-04-05 2009-01-08 Mikolaj Witold Styrc Kit Which Is Intended to Be Implanted in a Blood Vessel, and Associated Tubular Endoprosthesis
US8500802B2 (en) 2005-04-08 2013-08-06 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US7951197B2 (en) 2005-04-08 2011-05-31 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US8512399B2 (en) 2005-04-15 2013-08-20 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9861473B2 (en) 2005-04-15 2018-01-09 Boston Scientific Scimed Inc. Valve apparatus, system and method
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9649495B2 (en) 2005-04-25 2017-05-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
USD732666S1 (en) 2005-05-13 2015-06-23 Medtronic Corevalve, Inc. Heart valve prosthesis
US9504564B2 (en) 2005-05-13 2016-11-29 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US8226710B2 (en) 2005-05-13 2012-07-24 Medtronic Corevalve, Inc. Heart valve prosthesis and methods of manufacture and use
US8911493B2 (en) 2005-05-24 2014-12-16 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valves
US8500798B2 (en) 2005-05-24 2013-08-06 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US9554903B2 (en) 2005-05-24 2017-01-31 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US8211169B2 (en) 2005-05-27 2012-07-03 Medtronic, Inc. Gasket with collar for prosthetic heart valves and methods for using them
US8568477B2 (en) 2005-06-07 2013-10-29 Direct Flow Medical, Inc. Stentless aortic valve replacement with high radial strength
US9028542B2 (en) 2005-06-10 2015-05-12 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8506625B2 (en) 2005-07-13 2013-08-13 Edwards Lifesciences Corporation Contoured sewing ring for a prosthetic mitral heart valve
US20070016288A1 (en) * 2005-07-13 2007-01-18 Gurskis Donnell W Two-piece percutaneous prosthetic heart valves and methods for making and using them
US8136659B2 (en) 2005-09-13 2012-03-20 Sadra Medical, Inc. Two-part package for medical implant
US7712606B2 (en) 2005-09-13 2010-05-11 Sadra Medical, Inc. Two-part package for medical implant
US9393094B2 (en) 2005-09-13 2016-07-19 Boston Scientific Scimed, Inc. Two-part package for medical implant
US9474609B2 (en) 2005-09-21 2016-10-25 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US8672997B2 (en) 2005-09-21 2014-03-18 Boston Scientific Scimed, Inc. Valve with sinus
US7951189B2 (en) 2005-09-21 2011-05-31 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US8460365B2 (en) 2005-09-21 2013-06-11 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
DE102005051849B4 (en) * 2005-10-28 2010-01-21 JenaValve Technology Inc., Wilmington A device for implantation and fixation of prosthetic heart valves
US9044320B2 (en) 2005-10-28 2015-06-02 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US9402717B2 (en) 2005-10-28 2016-08-02 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
US8092521B2 (en) 2005-10-28 2012-01-10 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
USRE45790E1 (en) 2005-10-28 2015-11-03 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US8551160B2 (en) 2005-10-28 2013-10-08 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
WO2007048529A1 (en) * 2005-10-28 2007-05-03 Jenavalve Technology Inc. Device for implanting and fastening heart valve prostheses
US9855142B2 (en) 2005-10-28 2018-01-02 JenaValve Technologies, Inc. Device for the implantation and fixation of prosthetic valves
USRE45962E1 (en) 2005-10-28 2016-04-05 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
DE102005052628B4 (en) * 2005-11-04 2014-06-05 Jenavalve Technology Inc. Self-expanding, flexible wire mesh with integrated valve prosthesis for the transvascular cardiac valve replacement and a system comprising such a device and a delivery catheter
US20170020695A1 (en) * 2005-11-10 2017-01-26 Edwards Lifesciences Cardiaq Llc Percutaneous heart valve
US8287584B2 (en) * 2005-11-14 2012-10-16 Sadra Medical, Inc. Medical implant deployment tool
US20130013057A1 (en) * 2005-11-14 2013-01-10 Sadra Medical, Inc. Medical implant deployment tool
WO2007058847A2 (en) 2005-11-14 2007-05-24 Sadra Medical, Inc. Medical implant deployment tool
US9662207B2 (en) 2005-11-16 2017-05-30 Edwards Lifesciences Corporation Transapical method of delivering prosthetic heart valve
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US7799038B2 (en) 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US7967857B2 (en) 2006-01-27 2011-06-28 Medtronic, Inc. Gasket with spring collar for prosthetic heart valves and methods for making and using them
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US7740655B2 (en) 2006-04-06 2010-06-22 Medtronic Vascular, Inc. Reinforced surgical conduit for implantation of a stented valve therein
US8821569B2 (en) 2006-04-29 2014-09-02 Medtronic, Inc. Multiple component prosthetic heart valve assemblies and methods for delivering them
US8021161B2 (en) 2006-05-01 2011-09-20 Edwards Lifesciences Corporation Simulated heart valve root for training and testing
US20080039881A1 (en) * 2006-07-07 2008-02-14 The Cleveland Clinic Foundation Apparatus and method for assisting in the removal of a cardiac valve
US7815676B2 (en) 2006-07-07 2010-10-19 The Cleveland Clinic Foundation Apparatus and method for assisting in the removal of a cardiac valve
US9387071B2 (en) 2006-09-19 2016-07-12 Medtronic, Inc. Sinus-engaging valve fixation member
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8771346B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthetic fixation techniques using sandwiching
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8771345B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US9301834B2 (en) 2006-09-19 2016-04-05 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US9642704B2 (en) 2006-09-19 2017-05-09 Medtronic Ventor Technologies Ltd. Catheter for implanting a valve prosthesis
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US8414643B2 (en) 2006-09-19 2013-04-09 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8348995B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies, Ltd. Axial-force fixation member for valve
US8348996B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies Ltd. Valve prosthesis implantation techniques
US9827097B2 (en) 2006-09-19 2017-11-28 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US9138312B2 (en) 2006-09-19 2015-09-22 Medtronic Ventor Technologies Ltd. Valve prostheses
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US8876894B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Leaflet-sensitive valve fixation member
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US9572661B2 (en) 2006-10-19 2017-02-21 Direct Flow Medical, Inc. Profile reduction of valve implant
US8556881B2 (en) 2006-10-19 2013-10-15 Direct Flow Medical, Inc. Catheter guidance through a calcified aortic valve
US8133213B2 (en) 2006-10-19 2012-03-13 Direct Flow Medical, Inc. Catheter guidance through a calcified aortic valve
US7935144B2 (en) 2006-10-19 2011-05-03 Direct Flow Medical, Inc. Profile reduction of valve implant
US9883943B2 (en) 2006-12-05 2018-02-06 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US9351830B2 (en) 2006-12-05 2016-05-31 Valtech Cardio, Ltd. Implant and anchor placement
US9872769B2 (en) 2006-12-05 2018-01-23 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US8057539B2 (en) 2006-12-19 2011-11-15 Sorin Biomedica Cardio S.R.L. System for in situ positioning of cardiac valve prostheses without occluding blood flow
US8070799B2 (en) 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US8470024B2 (en) 2006-12-19 2013-06-25 Sorin Group Italia S.R.L. Device for in situ positioning of cardiac valve prosthesis
US9056008B2 (en) 2006-12-19 2015-06-16 Sorin Group Italia S.R.L. Instrument and method for in situ development of cardiac valve prostheses
US7993392B2 (en) 2006-12-19 2011-08-09 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US8133270B2 (en) 2007-01-08 2012-03-13 California Institute Of Technology In-situ formation of a valve
US8348999B2 (en) 2007-01-08 2013-01-08 California Institute Of Technology In-situ formation of a valve
US9421083B2 (en) 2007-02-05 2016-08-23 Boston Scientific Scimed Inc. Percutaneous valve, system and method
US7967853B2 (en) 2007-02-05 2011-06-28 Boston Scientific Scimed, Inc. Percutaneous valve, system and method
US8470023B2 (en) 2007-02-05 2013-06-25 Boston Scientific Scimed, Inc. Percutaneous valve, system, and method
US9504568B2 (en) * 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US20080243246A1 (en) * 2007-02-16 2008-10-02 Ryan Timothy R Replacement prosthetic heart valves and methods of implantation
US7871436B2 (en) 2007-02-16 2011-01-18 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US20080208327A1 (en) * 2007-02-27 2008-08-28 Rowe Stanton J Method and apparatus for replacing a prosthetic valve
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9585754B2 (en) 2007-04-20 2017-03-07 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US7785364B2 (en) 2007-06-08 2010-08-31 Laboratoires Perouse Kit to be implanted in a blood circulation conduit
US20080319538A1 (en) * 2007-06-08 2008-12-25 Mykolaj Styrc Kit to be implanted in a blood circulation conduit
US20100191326A1 (en) * 2007-06-26 2010-07-29 Alkhatib Yousef F Apparatus and method for implanting collapsible/expandable prosthetic heart valves
US8512398B2 (en) * 2007-06-26 2013-08-20 St. Jude Medical, Inc. Apparatus and method for implanting collapsible/expandable prosthetic heart valves
US9554905B2 (en) 2007-06-26 2017-01-31 St. Jude Medical, Inc. Apparatus and method for implanting collapsible/expandable prosthetic heart valves
US8795355B2 (en) 2007-06-26 2014-08-05 St. Jude Medical, Inc. Apparatus and method for implanting collapsible/expandable prosthetic heart valves
US9480564B2 (en) 2007-07-23 2016-11-01 Hocor Cardiovascular Technologies, Llc Methods and apparatus for percutaneous aortic valve replacement
US20090030510A1 (en) * 2007-07-23 2009-01-29 Ho Paul C Methods and apparatus for percutaneous aortic valve replacement
US20090030503A1 (en) * 2007-07-23 2009-01-29 Ho Paul C Method and apparatus for percutaneous aortic valve replacement
US8663318B2 (en) 2007-07-23 2014-03-04 Hocor Cardiovascular Technologies Llc Method and apparatus for percutaneous aortic valve replacement
US8663319B2 (en) 2007-07-23 2014-03-04 Hocor Cardiovascular Technologies Llc Methods and apparatus for percutaneous aortic valve replacement
US9700410B2 (en) 2007-07-23 2017-07-11 Hocor Cardiovascular Technologies Llc Method and apparatus for percutaneous aortic valve replacement
US8828079B2 (en) 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US9393112B2 (en) 2007-08-20 2016-07-19 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US9308360B2 (en) 2007-08-23 2016-04-12 Direct Flow Medical, Inc. Translumenally implantable heart valve with formed in place support
US8808367B2 (en) 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US8475521B2 (en) 2007-09-07 2013-07-02 Sorin Group Italia S.R.L. Streamlined delivery system for in situ deployment of cardiac valve prostheses
US8486137B2 (en) 2007-09-07 2013-07-16 Sorin Group Italia S.R.L. Streamlined, apical delivery system for in situ deployment of cardiac valve prostheses
US8114154B2 (en) 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US7846199B2 (en) 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
US8414641B2 (en) 2007-12-21 2013-04-09 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US8137394B2 (en) 2007-12-21 2012-03-20 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US8157852B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US8685077B2 (en) 2008-01-24 2014-04-01 Medtronics, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8696689B2 (en) 2008-03-18 2014-04-15 Medtronic Ventor Technologies Ltd. Medical suturing device and method for use thereof
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) * 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8511244B2 (en) 2008-04-23 2013-08-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US9314334B2 (en) 2008-11-25 2016-04-19 Edwards Lifesciences Corporation Conformal expansion of prosthetic devices to anatomical shapes
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
US9662209B2 (en) 2008-12-22 2017-05-30 Valtech Cardio, Ltd. Contractible annuloplasty structures
US9713530B2 (en) 2008-12-22 2017-07-25 Valtech Cardio, Ltd. Adjustable annuloplasty devices and adjustment mechanisms therefor
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US20100174363A1 (en) * 2009-01-07 2010-07-08 Endovalve, Inc. One Piece Prosthetic Valve Support Structure and Related Assemblies
US9402720B2 (en) 2009-01-12 2016-08-02 Valve Medical Ltd. Modular percutaneous valve structure and delivery method
US20100185275A1 (en) * 2009-01-12 2010-07-22 Valve Medical Ltd. Modular percutaneous valve structure and delivery method
US8021420B2 (en) 2009-03-12 2011-09-20 Medtronic Vascular, Inc. Prosthetic valve delivery system
US9144667B2 (en) 2009-03-12 2015-09-29 Medtronic Vascular, Inc. Prosthetic valve delivery system
US8273120B2 (en) 2009-03-12 2012-09-25 Medtronic Vascular, Inc. Prosthetic valve delivery system
US20100234940A1 (en) * 2009-03-12 2010-09-16 Medtronic Vascular , Inc. Prosthetic Valve Delivery System
US9248016B2 (en) 2009-03-31 2016-02-02 Edwards Lifesciences Corporation Prosthetic heart valve system
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US9474606B2 (en) 2009-05-04 2016-10-25 Valtech Cardio, Ltd. Over-wire implant contraction methods
US8353953B2 (en) 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
US8403982B2 (en) 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US9168105B2 (en) 2009-05-13 2015-10-27 Sorin Group Italia S.R.L. Device for surgical interventions
US8696742B2 (en) 2009-06-26 2014-04-15 Edwards Lifesciences Corporation Unitary quick-connect prosthetic heart valve deployment methods
US9005277B2 (en) 2009-06-26 2015-04-14 Edwards Lifesciences Corporation Unitary quick-connect prosthetic heart valve deployment system
US8348998B2 (en) 2009-06-26 2013-01-08 Edwards Lifesciences Corporation Unitary quick connect prosthetic heart valve and deployment system and methods
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US9603553B2 (en) 2009-10-27 2017-03-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US8449625B2 (en) 2009-10-27 2013-05-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US9414921B2 (en) 2009-10-29 2016-08-16 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US9622861B2 (en) 2009-12-02 2017-04-18 Valtech Cardio, Ltd. Tool for actuating an adjusting mechanism
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US20130123914A1 (en) * 2010-03-01 2013-05-16 Colibri Heart Valve Llc Percutaneously deliverable heart valve and methods associated therewith
US20110224785A1 (en) * 2010-03-10 2011-09-15 Hacohen Gil Prosthetic mitral valve with tissue anchors
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
WO2011139594A2 (en) 2010-04-27 2011-11-10 Medtronic, Inc. Artificial bursa for intra-articular drug delivery
US8986374B2 (en) 2010-05-10 2015-03-24 Edwards Lifesciences Corporation Prosthetic heart valve
US9554901B2 (en) 2010-05-12 2017-01-31 Edwards Lifesciences Corporation Low gradient prosthetic heart valve
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9744031B2 (en) 2010-05-25 2017-08-29 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US8992604B2 (en) 2010-07-21 2015-03-31 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US9132009B2 (en) * 2010-07-21 2015-09-15 Mitraltech Ltd. Guide wires with commissural anchors to advance a prosthetic valve
US20120022639A1 (en) * 2010-07-21 2012-01-26 Hacohen Gil Guide wires with commissural anchors to advance a prosthetic valve
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US9017399B2 (en) 2010-07-21 2015-04-28 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US9433503B2 (en) 2010-08-04 2016-09-06 Valcare, Inc. Percutaneous transcatheter repair of heart valves
WO2012031141A3 (en) * 2010-09-01 2012-06-07 Maurice Buchbinder Cardiac valve support structure
JP2013539395A (en) * 2010-09-01 2013-10-24 ムバルブ・テクノロジーズ・リミテツド Heart valve support structure
US9301836B2 (en) 2010-09-01 2016-04-05 Mvalve Technologies Ltd. Cardiac valve support structure
CN103237523A (en) * 2010-09-01 2013-08-07 M阀门技术有限公司 Cardiac valve support structure
US8641757B2 (en) 2010-09-10 2014-02-04 Edwards Lifesciences Corporation Systems for rapidly deploying surgical heart valves
US9370418B2 (en) 2010-09-10 2016-06-21 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9504563B2 (en) 2010-09-10 2016-11-29 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9125741B2 (en) 2010-09-10 2015-09-08 Edwards Lifesciences Corporation Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves
US8845720B2 (en) 2010-09-27 2014-09-30 Edwards Lifesciences Corporation Prosthetic heart valve frame with flexible commissures
US9861479B2 (en) 2010-09-27 2018-01-09 Edwards Lifesciences Corporation Methods of delivery of flexible heart valves
US9737400B2 (en) 2010-12-14 2017-08-22 Colibri Heart Valve Llc Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
US9770331B2 (en) 2010-12-23 2017-09-26 Twelve, Inc. System for mitral valve repair and replacement
US9421098B2 (en) 2010-12-23 2016-08-23 Twelve, Inc. System for mitral valve repair and replacement
WO2012103204A2 (en) * 2011-01-25 2012-08-02 Emory University Systems, devices and methods for surgical and precutaneous replacement of a valve
WO2012103204A3 (en) * 2011-01-25 2012-11-22 Emory University Systems, devices and methods for surgical and precutaneous replacement of a valve
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9402721B2 (en) 2011-06-01 2016-08-02 Valcare, Inc. Percutaneous transcatheter repair of heart valves via trans-apical access
US9585751B2 (en) 2011-06-21 2017-03-07 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US9579196B2 (en) 2011-06-21 2017-02-28 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US9572662B2 (en) 2011-06-21 2017-02-21 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US9125740B2 (en) 2011-06-21 2015-09-08 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US9364326B2 (en) 2011-06-29 2016-06-14 Mitralix Ltd. Heart valve repair devices and methods
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
US9387078B2 (en) 2011-08-05 2016-07-12 Mitraltech Ltd. Percutaneous mitral valve replacement and sealing
US9295552B2 (en) 2011-10-19 2016-03-29 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9034033B2 (en) 2011-10-19 2015-05-19 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9034032B2 (en) 2011-10-19 2015-05-19 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9039757B2 (en) 2011-10-19 2015-05-26 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9763780B2 (en) 2011-10-19 2017-09-19 Twelve, Inc. Devices, systems and methods for heart valve replacement
US9655722B2 (en) 2011-10-19 2017-05-23 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US8858623B2 (en) 2011-11-04 2014-10-14 Valtech Cardio, Ltd. Implant having multiple rotational assemblies
US9775709B2 (en) 2011-11-04 2017-10-03 Valtech Cardio, Ltd. Implant having multiple adjustable mechanisms
US9265608B2 (en) 2011-11-04 2016-02-23 Valtech Cardio, Ltd. Implant having multiple rotational assemblies
US9724192B2 (en) 2011-11-08 2017-08-08 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US9555219B2 (en) 2011-11-10 2017-01-31 Boston Scientific Scimed, Inc. Direct connect flush system
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US9642705B2 (en) 2011-11-15 2017-05-09 Boston Scientific Scimed Inc. Bond between components of a medical device
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
US9078747B2 (en) 2011-12-21 2015-07-14 Edwards Lifesciences Corporation Anchoring device for replacing or repairing a heart valve
US9138314B2 (en) 2011-12-29 2015-09-22 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US9180008B2 (en) 2012-02-29 2015-11-10 Valcare, Inc. Methods, devices, and systems for percutaneously anchoring annuloplasty rings
US9814576B2 (en) 2012-02-29 2017-11-14 Valcare, Inc. Methods, devices, and systems for percutaneously anchoring annuloplasty rings
US9839519B2 (en) 2012-02-29 2017-12-12 Valcare, Inc. Percutaneous annuloplasty system with anterior-posterior adjustment
US9579198B2 (en) 2012-03-01 2017-02-28 Twelve, Inc. Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
US9566152B2 (en) * 2012-04-19 2017-02-14 Caisson Interventional, LLC Heart valve assembly and methods
US20140236291A1 (en) * 2012-04-19 2014-08-21 Caisson Interventional Llc Valve replacement systems and methods
US9427315B2 (en) 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
US20150209138A1 (en) * 2012-04-19 2015-07-30 Caisson Interventional, LLC Heart valve assembly and methods
US9427316B2 (en) * 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9730793B2 (en) 2012-12-06 2017-08-15 Valtech Cardio, Ltd. Techniques for guide-wire based advancement of a tool
US9681952B2 (en) 2013-01-24 2017-06-20 Mitraltech Ltd. Anchoring of prosthetic valve supports
CN105263442A (en) * 2013-02-04 2016-01-20 托尔福公司 Hydraulic delivery systems for prosthetic heart valve devices and associated methods
US9744037B2 (en) 2013-03-15 2017-08-29 California Institute Of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
WO2014189509A1 (en) * 2013-05-22 2014-11-27 Nadav Yellin Transcatheter prosthetic valve for mitral or tricuspid valve replacement
US9468527B2 (en) 2013-06-12 2016-10-18 Edwards Lifesciences Corporation Cardiac implant with integrated suture fasteners
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9050188B2 (en) 2013-10-23 2015-06-09 Caisson Interventional, LLC Methods and systems for heart valve therapy
US9421094B2 (en) 2013-10-23 2016-08-23 Caisson Interventional, LLC Methods and systems for heart valve therapy
US9610162B2 (en) 2013-12-26 2017-04-04 Valtech Cardio, Ltd. Implantation of flexible implant
US9393111B2 (en) 2014-01-15 2016-07-19 Sino Medical Sciences Technology Inc. Device and method for mitral valve regurgitation treatment
US9549816B2 (en) 2014-04-03 2017-01-24 Edwards Lifesciences Corporation Method for manufacturing high durability heart valve
US9585752B2 (en) 2014-04-30 2017-03-07 Edwards Lifesciences Corporation Holder and deployment system for surgical heart valves
US9687345B2 (en) 2014-05-29 2017-06-27 Edwards Lifesciences Cardiaq Llc Prosthesis, delivery device and methods of use
US9504566B2 (en) 2014-06-20 2016-11-29 Edwards Lifesciences Corporation Surgical heart valves identifiable post-implant
US9700412B2 (en) 2014-06-26 2017-07-11 Mitralix Ltd. Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices
US9750607B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750605B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750606B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US20160220367A1 (en) * 2015-02-04 2016-08-04 Medtronic Vascular, Inc. Balloon valvuloplasty delivery system
USD800908S1 (en) 2016-08-10 2017-10-24 Mitraltech Ltd. Prosthetic valve element

Also Published As

Publication number Publication date Type
EP1164976A4 (en) 2005-03-16 application
US6425916B1 (en) 2002-07-30 grant
WO2000047139A9 (en) 2001-09-13 application
CA2360185C (en) 2008-12-30 grant
EP1164976A1 (en) 2002-01-02 application
CA2360185A1 (en) 2000-08-17 application
JP4233765B2 (en) 2009-03-04 grant
WO2000047139A1 (en) 2000-08-17 application
JP2002536115A (en) 2002-10-29 application

Similar Documents

Publication Publication Date Title
US7988724B2 (en) Systems and methods for delivering a medical implant
US8348998B2 (en) Unitary quick connect prosthetic heart valve and deployment system and methods
US7041132B2 (en) Percutaneously delivered heart valve and delivery means thereof
US6290728B1 (en) Designs for left ventricular conduit
US7892281B2 (en) Prosthetic valve for transluminal delivery
US7381218B2 (en) System and method for implanting a two-part prosthetic heart valve
US8858620B2 (en) Methods and apparatus for endovascularly replacing a heart valve
US8075611B2 (en) Stented prosthetic heart valves
US7824442B2 (en) Methods and apparatus for endovascularly replacing a heart valve
US6830585B1 (en) Percutaneously deliverable heart valve and methods of implantation
US7837727B2 (en) Minimally invasive heart valve replacement
US7276078B2 (en) Paravalvular leak detection, sealing, and prevention
US7331991B2 (en) Implantable small percutaneous valve and methods of delivery
US6926690B2 (en) Transmyocardial shunt and its attachment mechanism, for left ventricular revascularization
US20050137691A1 (en) Two piece heart valve and anchor
US8551161B2 (en) Cardiac valve annulus restraining device
US20120078357A1 (en) Prosthetic Heart Valve Frame With Flexible Commissures
US20040078072A1 (en) Delivery system for a stentless valve bioprosthesis
US7175656B2 (en) Percutaneous transcatheter heart valve replacement
US6540782B1 (en) Artificial heart valve
US20110166636A1 (en) Method and Apparatus for Replacing a Prosthetic Valve
US6951571B1 (en) Valve implanting device
US7972378B2 (en) Stents for prosthetic heart valves
US6821297B2 (en) Artificial heart valve, implantation instrument and method therefor
US20080097595A1 (en) Intraventricular cardiac prosthesis