UA95480C2 - Заміщені карбоксаміди - Google Patents

Заміщені карбоксаміди

Info

Publication number
UA95480C2
UA95480C2 UAA200813907A UAA200813907A UA95480C2 UA 95480 C2 UA95480 C2 UA 95480C2 UA A200813907 A UAA200813907 A UA A200813907A UA A200813907 A UAA200813907 A UA A200813907A UA 95480 C2 UA95480 C2 UA 95480C2
Authority
UA
Ukraine
Prior art keywords
substituted carboxamides
substituted
carboxamides
formula
pharmaceutically acceptable
Prior art date
Application number
UAA200813907A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Райан Томас Бакер
Метью Джозеф Фішер
Стівен Лі Кукліш
Шон Патрік Голлінзхед
Едвард К.Р. Сміт
Куміко Такеучі
Original Assignee
Елі Ліллі Енд Компані
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Елі Ліллі Енд Компані filed Critical Елі Ліллі Енд Компані
Publication of UA95480C2 publication Critical patent/UA95480C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UAA200813907A 2006-06-08 2007-06-07 Заміщені карбоксаміди UA95480C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81183906P 2006-06-08 2006-06-08
PCT/US2007/070572 WO2008103185A2 (en) 2006-06-08 2007-06-07 Substituted carboxamides as group i metabotropic receptor antagonists

Publications (1)

Publication Number Publication Date
UA95480C2 true UA95480C2 (uk) 2011-08-10

Family

ID=39673278

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200813907A UA95480C2 (uk) 2006-06-08 2007-06-07 Заміщені карбоксаміди

Country Status (30)

Country Link
US (1) US7960419B2 (enExample)
EP (1) EP2076502B1 (enExample)
JP (1) JP5108878B2 (enExample)
KR (1) KR101051559B1 (enExample)
CN (1) CN101466691B (enExample)
AT (1) ATE509921T1 (enExample)
AU (1) AU2007347428B2 (enExample)
BR (1) BRPI0712862A2 (enExample)
CA (1) CA2652074C (enExample)
CR (1) CR10410A (enExample)
CY (1) CY1111588T1 (enExample)
DK (1) DK2076502T3 (enExample)
EA (1) EA014233B1 (enExample)
EC (1) ECSP088939A (enExample)
ES (1) ES2362949T3 (enExample)
HR (1) HRP20110436T1 (enExample)
IL (1) IL195632A (enExample)
MA (1) MA30620B1 (enExample)
MX (1) MX2008015485A (enExample)
MY (1) MY148084A (enExample)
NO (1) NO341474B1 (enExample)
NZ (1) NZ573352A (enExample)
PL (1) PL2076502T3 (enExample)
PT (1) PT2076502E (enExample)
RS (1) RS51818B (enExample)
SI (1) SI2076502T1 (enExample)
TN (1) TNSN08506A1 (enExample)
UA (1) UA95480C2 (enExample)
WO (1) WO2008103185A2 (enExample)
ZA (1) ZA200809111B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0804685D0 (en) 2008-03-13 2008-04-16 Univ Edinburgh Therapeutic compounds and their use
AR070986A1 (es) 2008-04-04 2010-05-19 Lilly Co Eli Compuesto de 3-indazoil-4 -piridilisotiazoles, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para tratar la ansiedad
WO2010146338A1 (en) * 2009-06-15 2010-12-23 The University Of Edinburgh Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders
DK2477983T3 (en) 2009-09-16 2015-06-29 Univ Edinburgh (4-phenyl-piperidin-1-yl) - [5-1H-pyrazol-4-yl) -thiophene-3-yl] -METHANONFORBINDELSER AND THEIR USE
BR112012027640B1 (pt) 2010-04-29 2021-08-03 The University Of Edinburgh Composto, composição farmacêutica, e, métodos de preparar uma composição farmacêutica, de inibir a função da 11beta-hidroxiesteroide desidrogenase do tipo 1
KR102160841B1 (ko) 2012-11-13 2020-09-28 닛산 가가쿠 가부시키가이샤 2-피리돈 화합물
SG11201902588PA (en) 2016-09-23 2019-05-30 Bayer Ag N3-Cyclically Substituted Thienouracils And Use Thereof
CN117567266B (zh) * 2023-11-07 2024-06-14 康龙化成手性医药技术(宁波)有限公司 一种制备2-甲基环丙羧酸的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL72091A0 (en) * 1983-06-20 1984-10-31 Lilly Co Eli N'-substituted(3-aryl 5-isothiazolyl)urea derivatives
DE4328425A1 (de) 1993-08-24 1995-03-02 Basf Ag Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung
DK124393D0 (da) * 1993-11-03 1993-11-03 Lundbeck & Co As H Compounds
DE19542372A1 (de) * 1995-11-14 1997-05-15 Bayer Ag Acylierte 5-Aminoisothiazole
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
JP3411262B2 (ja) * 1999-08-20 2003-05-26 萬有製薬株式会社 新規スピロ化合物
NZ530782A (en) * 2001-08-06 2005-11-25 Pharmacia Italia S Aminoisoxazole derivatives active as kinase inhibitors
US20060281803A1 (en) * 2003-09-23 2006-12-14 Lindsley Craig W Pyrazole modulators of metabotropic glutamate receptors
CN1984899B (zh) * 2004-05-12 2011-07-27 先灵公司 Cxcr1和cxcr2趋化因子拮抗剂
WO2006033005A2 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Thrombopoietin receptor agonists

Also Published As

Publication number Publication date
IL195632A0 (en) 2009-09-01
EP2076502A2 (en) 2009-07-08
JP5108878B2 (ja) 2012-12-26
CR10410A (es) 2008-11-28
SI2076502T1 (sl) 2011-09-30
EA200870516A1 (ru) 2009-06-30
AU2007347428B2 (en) 2012-02-09
PL2076502T3 (pl) 2011-09-30
ZA200809111B (en) 2009-12-30
CY1111588T1 (el) 2015-10-07
ES2362949T3 (es) 2011-07-15
CN101466691B (zh) 2011-07-27
NO341474B1 (no) 2017-11-27
WO2008103185A2 (en) 2008-08-28
IL195632A (en) 2013-11-28
US20090182025A1 (en) 2009-07-16
PT2076502E (pt) 2011-06-07
EA014233B1 (ru) 2010-10-29
MY148084A (en) 2013-02-28
US7960419B2 (en) 2011-06-14
TNSN08506A1 (en) 2010-04-14
DK2076502T3 (da) 2011-07-25
CA2652074C (en) 2013-08-06
MA30620B1 (fr) 2009-08-03
WO2008103185A3 (en) 2008-10-30
NZ573352A (en) 2011-10-28
CA2652074A1 (en) 2008-08-28
HK1131984A1 (en) 2010-02-12
KR20090008460A (ko) 2009-01-21
EP2076502B1 (en) 2011-05-18
NO20085028L (no) 2008-12-02
BRPI0712862A2 (pt) 2012-12-18
CN101466691A (zh) 2009-06-24
RS51818B (sr) 2011-12-31
ECSP088939A (es) 2009-01-30
MX2008015485A (es) 2009-03-06
HRP20110436T1 (hr) 2011-08-31
ATE509921T1 (de) 2011-06-15
JP2009539874A (ja) 2009-11-19
AU2007347428A1 (en) 2008-08-28
KR101051559B1 (ko) 2011-07-22

Similar Documents

Publication Publication Date Title
IL195632A0 (en) Substituted carboxamides
MY146662A (en) Novel n-(8-heteroaryltetrahydronaphtalene-2yl) or n-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain
TW201000473A (en) Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
TW200806299A (en) Treatment of pain
TW200806300A (en) New therapeutic combinations for the treatment of depression
SI2205244T1 (sl) Postopki dajanja N-(5-terc.-butil-izoksazol-3-il)-N'-(4-(7-(2-morfolin- 4-il-etoksi-)imidazo-2,1-b)-(1,3)-benzotiazol-2-il)-fenil)sečnine za zdravljenje proliferativne bolezni
MX2010008460A (es) Derivado de tiazol y su uso como inhibidor de proteina-1 de adhesion vascular.
UA93709C2 (ru) 12-имидазолил-1-додеканол и его применение b изготовлении фармацевтических композиций
ZA200806778B (en) N-Hydroxyacrylamide compounds
TW200738653A (en) Anthranilamide/2-amino-heteroarene carboxamide derivatives
MX2009005798A (es) Recuperacion de apoplejia.
TW200639159A (en) Treatment of pain
MX2009006325A (es) Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales.
TW200806321A (en) New therapeutic combinations for the treatment or prevention of psychotic disorders
MX2010008586A (es) Amidas de acido 3-(4-fluorofenil)-3-hidroxi-2-amino-propionico y compuestos relacionados que tienen actividad analgesica.
IL197769A (en) The history of morphine, medicinal preparations containing them and their use in the preparation of pain medication
WO2007144889A3 (en) Treatment of neurofibromatosis
WO2008130321A3 (en) Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
MX2009010162A (es) Metodo para tratar dolor mediado por el receptor cb2.
MX2009010164A (es) Metodo para tratar dolor mediado por el receptor cb2.
EA200701086A1 (ru) Производные изоксазола, их фармацевтические композиции и способ лечения невропатической боли
UA103767C2 (ru) Карбоксамидные соединения для лечения метаболических расстройств
JO2586B1 (en) Use of different sulfamide derivatives combined with benzo ring for pain management