UA94025C2 - Применение антагонистов рецептора св1 для производства композиции для лечения фиброза печени - Google Patents

Применение антагонистов рецептора св1 для производства композиции для лечения фиброза печени

Info

Publication number
UA94025C2
UA94025C2 UAA200610602A UAA200610602A UA94025C2 UA 94025 C2 UA94025 C2 UA 94025C2 UA A200610602 A UAA200610602 A UA A200610602A UA A200610602 A UAA200610602 A UA A200610602A UA 94025 C2 UA94025 C2 UA 94025C2
Authority
UA
Ukraine
Prior art keywords
antagonists
receptor
treatment
liver fibrosis
manufacture
Prior art date
Application number
UAA200610602A
Other languages
English (en)
Ukrainian (uk)
Inventor
Софи Лотерштайн
Ариан Малла
Паскаль Гренар
Борис Жюльен
ван Нхье Жанна Тран
Original Assignee
Энсерм
Санофи-Авентис
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Энсерм, Санофи-Авентис filed Critical Энсерм
Publication of UA94025C2 publication Critical patent/UA94025C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Изобретение касается применения антагонистов рецептора СВ1 для производства композиции, полезной в лечении фиброза печени, и, преимущественно, применение производных N-пиперидин-3-пиразолкарбоксамида.
UAA200610602A 2004-03-09 2005-03-08 Применение антагонистов рецептора св1 для производства композиции для лечения фиброза печени UA94025C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04290633A EP1574211A1 (en) 2004-03-09 2004-03-09 Use of antagonists of the CB1 receptor for the manufacture of a composition useful for the treatment of hepatic diseases

Publications (1)

Publication Number Publication Date
UA94025C2 true UA94025C2 (ru) 2011-04-11

Family

ID=34814417

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200610602A UA94025C2 (ru) 2004-03-09 2005-03-08 Применение антагонистов рецептора св1 для производства композиции для лечения фиброза печени

Country Status (27)

Country Link
US (2) US8236763B2 (ru)
EP (3) EP1574211A1 (ru)
JP (1) JP2007527893A (ru)
KR (1) KR20070026415A (ru)
CN (1) CN1929828A (ru)
AR (1) AR048087A1 (ru)
AT (1) ATE520393T1 (ru)
AU (1) AU2005218937B2 (ru)
BR (1) BRPI0508560A (ru)
CA (1) CA2557976A1 (ru)
CY (1) CY1112078T1 (ru)
DK (1) DK1725223T3 (ru)
ES (1) ES2371552T3 (ru)
HK (1) HK1094674A1 (ru)
IL (1) IL177465A0 (ru)
MA (1) MA28454B1 (ru)
MX (1) MXPA06010287A (ru)
NO (1) NO20064603L (ru)
PL (1) PL1725223T3 (ru)
PT (1) PT1725223E (ru)
RU (1) RU2402328C2 (ru)
SI (1) SI1725223T1 (ru)
TN (1) TNSN06272A1 (ru)
TW (1) TWI337540B (ru)
UA (1) UA94025C2 (ru)
WO (1) WO2005084652A2 (ru)
ZA (1) ZA200607159B (ru)

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US7875647B2 (en) 2006-09-29 2011-01-25 Green Cross Corporation Heteroaryl-pyrazole derivatives as cannabinoid CB1 receptor antagonists
EP2593477A2 (en) * 2010-07-15 2013-05-22 Oleg Iliich Epshtein Pharmaceutical compositions and methods of treatment
US20120288442A1 (en) * 2011-05-11 2012-11-15 Atomic Energy Council-Institute Of Nuclear Energy Research Nuclear Imaging Method Using Molecular Target Detection Agent for Liver Fibrosis
US11155521B2 (en) 2012-11-13 2021-10-26 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cannabinoid receptor mediating compounds
EP2919779B1 (en) 2012-11-13 2021-01-06 The U.S.A. as represented by the Secretary, Department of Health and Human Services Cannabinoid receptor mediating compounds
WO2015148984A2 (en) 2014-03-27 2015-10-01 Ruiyi Inc. Antibodies that bind human cannabinoid 1 (cb1) receptor
CN106660968B (zh) 2014-05-09 2020-02-07 美国政府(由卫生和人类服务部的部长所代表) 吡唑衍生物及其作为大麻素受体介体的用途
AU2016330471B2 (en) 2015-09-30 2022-09-29 Bird Rock Bio, Inc. Antibodies that bind human cannabinoid 1 (CB1) receptor
WO2017184412A1 (en) * 2016-04-18 2017-10-26 Eli Lilly And Company Purine cannabinoid agonist for treating nonalcoholic steatohepatitis and fibrosis

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AT394493B (de) * 1989-05-11 1992-04-10 Homosan Ag Pharmazeutisches praeparat zur behandlung von lebererkrankungen
US5492891A (en) * 1991-09-05 1996-02-20 Novo Nordisk A/S Method for treatment of patients with chronic liver disease
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
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Also Published As

Publication number Publication date
WO2005084652A3 (en) 2005-12-08
CN1929828A (zh) 2007-03-14
US8236763B2 (en) 2012-08-07
TWI337540B (en) 2011-02-21
TW200534851A (en) 2005-11-01
US8604060B2 (en) 2013-12-10
ZA200607159B (en) 2008-02-27
CY1112078T1 (el) 2015-11-04
EP1725223B1 (en) 2011-08-17
BRPI0508560A (pt) 2007-08-14
AU2005218937B2 (en) 2011-07-07
NO20064603L (no) 2006-10-09
CA2557976A1 (en) 2005-09-15
AR048087A1 (es) 2006-03-29
TNSN06272A1 (en) 2007-12-03
AU2005218937A1 (en) 2005-09-15
EP2305220B1 (en) 2014-07-30
IL177465A0 (en) 2007-07-04
ES2371552T3 (es) 2012-01-05
KR20070026415A (ko) 2007-03-08
RU2006134707A (ru) 2008-04-20
EP1725223A2 (en) 2006-11-29
PL1725223T3 (pl) 2012-01-31
MXPA06010287A (es) 2007-02-14
EP1574211A1 (en) 2005-09-14
HK1094674A1 (en) 2007-05-18
RU2402328C2 (ru) 2010-10-27
EP2305220A3 (en) 2011-05-18
MA28454B1 (fr) 2007-03-01
US20120329833A1 (en) 2012-12-27
ATE520393T1 (de) 2011-09-15
WO2005084652A2 (en) 2005-09-15
PT1725223E (pt) 2011-12-02
US20080214449A1 (en) 2008-09-04
DK1725223T3 (da) 2011-11-28
SI1725223T1 (sl) 2012-01-31
JP2007527893A (ja) 2007-10-04
EP2305220A2 (en) 2011-04-06

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