UA77393C2 - Non-viral vector for introduction of nucleic acid and a process for preparation thereof, condensed complex polypeptide/nucleic acid and a process for insertion of nucleic acid of interest, into eukaryotic cell - Google Patents
Non-viral vector for introduction of nucleic acid and a process for preparation thereof, condensed complex polypeptide/nucleic acid and a process for insertion of nucleic acid of interest, into eukaryotic cell Download PDFInfo
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- UA77393C2 UA77393C2 UA2002076053A UA2002076053A UA77393C2 UA 77393 C2 UA77393 C2 UA 77393C2 UA 2002076053 A UA2002076053 A UA 2002076053A UA 2002076053 A UA2002076053 A UA 2002076053A UA 77393 C2 UA77393 C2 UA 77393C2
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- polypeptide
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930533.6A GB9930533D0 (en) | 1999-12-23 | 1999-12-23 | Nucleic acid delivery |
| PCT/GB2000/004767 WO2001048233A1 (en) | 1999-12-23 | 2000-12-12 | Viral core protein-cationic lipid-nucleic acid-delivery complexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA77393C2 true UA77393C2 (en) | 2006-12-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| UA2002076053A UA77393C2 (en) | 1999-12-23 | 2000-12-12 | Non-viral vector for introduction of nucleic acid and a process for preparation thereof, condensed complex polypeptide/nucleic acid and a process for insertion of nucleic acid of interest, into eukaryotic cell |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20030153081A1 (ru) |
| EP (2) | EP1244805B1 (ru) |
| JP (1) | JP2003518388A (ru) |
| CN (1) | CN100354426C (ru) |
| AT (1) | ATE318322T1 (ru) |
| AU (1) | AU781356B2 (ru) |
| CA (1) | CA2395454A1 (ru) |
| CZ (1) | CZ298353B6 (ru) |
| DE (1) | DE60026164T2 (ru) |
| DK (1) | DK1244805T3 (ru) |
| ES (1) | ES2258986T3 (ru) |
| GB (1) | GB9930533D0 (ru) |
| PT (1) | PT1244805E (ru) |
| RU (1) | RU2267536C2 (ru) |
| UA (1) | UA77393C2 (ru) |
| WO (1) | WO2001048233A1 (ru) |
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| JP4629333B2 (ja) * | 2001-08-29 | 2011-02-09 | アベンティス・ファーマ・ソシエテ・アノニム | アミノグリコシドの脂質誘導体 |
| FR2829136B1 (fr) * | 2001-08-29 | 2006-11-17 | Aventis Pharma Sa | Derives lipidiques d'aminoglycosides |
| US7906122B2 (en) | 2003-06-18 | 2011-03-15 | Yissum Research Development Company Of The Hebrew University Of Jersusalem | Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination |
| BRPI0411505A (pt) | 2003-06-18 | 2006-07-25 | Yissum Res Dev Co | uso de um composto, método para modular a resposta imune de um indivìduo, composição farmacêutica, vacina, complexo, e, kit para a captura de uma molécula biologicamente ativa |
| GB0418172D0 (en) * | 2004-08-13 | 2004-09-15 | Ic Vec Ltd | Vector |
| US20090155853A1 (en) * | 2005-11-18 | 2009-06-18 | Gary Nabel | Non-viral gene delivery complex |
| US20110002851A1 (en) * | 2006-11-03 | 2011-01-06 | Medigene Ag | Cationic Colloidal Carriers for Delivery of Active Agents to the Blood-Brain Barrier in the Course of Neuroinflammatory Diseases |
| EP2080767A4 (en) * | 2006-11-09 | 2012-03-28 | Daiichi Sankyo Co Ltd | COMPOSITION FOR THE INTRODUCTION OF NUCLEIC ACID |
| EP2105145A1 (en) | 2008-03-27 | 2009-09-30 | ETH Zürich | Method for muscle-specific delivery lipid-conjugated oligonucleotides |
| WO2010042751A2 (en) * | 2008-10-08 | 2010-04-15 | Chimeros Inc. | Chimeric therapeutics, compositions, and methods for using same |
| EP3207944B1 (en) | 2008-11-10 | 2020-01-15 | Arbutus Biopharma Corporation | Novel lipids and compositions for the delivery of therapeutics |
| WO2010120874A2 (en) * | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Chimeric therapeutics, compositions, and methods for using same |
| EP2747774A4 (en) | 2011-09-09 | 2015-02-11 | Biomed Realty L P | METHOD AND COMPOSITIONS FOR CONTROLLING VIRUS PROTECTION |
| AU2012347637B2 (en) | 2011-12-07 | 2017-09-14 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| RS63848B1 (sr) | 2014-06-25 | 2023-01-31 | Acuitas Therapeutics Inc | Novi lipidi i formulacije lipidnih nanočestica za isporuku nukleinskih kiselina |
| CN107922364B (zh) | 2015-06-29 | 2021-12-31 | 爱康泰生治疗公司 | 用于递送核酸的脂质和脂质纳米颗粒制剂 |
| US10829787B2 (en) * | 2015-10-14 | 2020-11-10 | Life Technologies Corporation | Ribonucleoprotein transfection agents |
| JP7030690B2 (ja) | 2015-10-28 | 2022-03-07 | アキィタス・セラピューティクス・インコーポレイテッド | 核酸のデリバリーのための新規脂質および脂質ナノ粒子製剤 |
| US20190336611A1 (en) * | 2016-06-09 | 2019-11-07 | Curevac Ag | Hybrid carriers for nucleic acid cargo |
| EP3468613A1 (en) | 2016-06-09 | 2019-04-17 | CureVac AG | Hybrid carriers for nucleic acid cargo |
| US11357856B2 (en) | 2017-04-13 | 2022-06-14 | Acuitas Therapeutics, Inc. | Lipids for delivery of active agents |
| US11596679B2 (en) | 2017-04-27 | 2023-03-07 | Vanderbilt University | Hepatitis C virus gene sequences and methods of use therefor |
| AU2018256877B2 (en) | 2017-04-28 | 2022-06-02 | Acuitas Therapeutics, Inc. | Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| WO2019036008A1 (en) | 2017-08-16 | 2019-02-21 | Acuitas Therapeutics, Inc. | LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS |
| WO2019036030A1 (en) | 2017-08-17 | 2019-02-21 | Acuitas Therapeutics, Inc. | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS |
| WO2019036028A1 (en) | 2017-08-17 | 2019-02-21 | Acuitas Therapeutics, Inc. | LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS |
| WO2020146805A1 (en) | 2019-01-11 | 2020-07-16 | Acuitas Therapeutics, Inc. | Lipids for lipid nanoparticle delivery of active agents |
| JP2021016370A (ja) * | 2019-07-23 | 2021-02-15 | 株式会社東芝 | 核酸導入キャリア、核酸導入キャリアセット、核酸導入組成物及び核酸導入方法 |
| CN110408656A (zh) * | 2019-07-29 | 2019-11-05 | 成都朴名生物科技有限公司 | 脂多聚物体及其制备方法、采用脂多聚物体将基因编辑质粒导入真核细胞的方法 |
| CN110452303B (zh) * | 2019-08-08 | 2022-03-04 | 中国科学院武汉病毒研究所 | 共价连接核酸和肽或蛋白的方法及应用 |
| CN111394313A (zh) * | 2020-04-01 | 2020-07-10 | 河南科技学院 | 一种人造细胞及其制备方法 |
| EP4182297A1 (en) | 2020-07-16 | 2023-05-24 | Acuitas Therapeutics, Inc. | Cationic lipids for use in lipid nanoparticles |
| CN114656422B (zh) * | 2022-04-22 | 2023-05-23 | 重庆理工大学 | 一种新型氮杂冠醚化合物及其阳离子脂质体、制备方法与应用 |
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| CH574396A5 (ru) * | 1969-12-29 | 1976-04-15 | Richter Gedeon Vegyeszet | |
| US4189431A (en) * | 1975-08-04 | 1980-02-19 | The Board of Trustees of Leland Stanford Junior University | Alkinyl terminating groups in biogenetic-like cyclizations to steroids |
| US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| IL112372A (en) * | 1994-02-07 | 2001-08-26 | Res Dev Foundation | Non-viral vector for the delivery of genetic information to cells |
| US5510510A (en) * | 1994-05-10 | 1996-04-23 | Bristol-Meyers Squibb Company | Inhibitors of farnesyl protein transferase |
| AU5979296A (en) * | 1995-06-07 | 1996-12-30 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| US6051429A (en) * | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| CN1181422A (zh) * | 1996-10-31 | 1998-05-13 | 上海市肿瘤研究所 | 与生长因子受体结合的多肽所构建的基因转移载体 |
| DK1163258T3 (da) * | 1999-03-09 | 2003-03-31 | Akzo Nobel Nv | Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis |
-
1999
- 1999-12-23 GB GBGB9930533.6A patent/GB9930533D0/en not_active Ceased
-
2000
- 2000-12-12 DK DK00981481T patent/DK1244805T3/da active
- 2000-12-12 US US10/168,909 patent/US20030153081A1/en not_active Abandoned
- 2000-12-12 EP EP00981481A patent/EP1244805B1/en not_active Expired - Lifetime
- 2000-12-12 ES ES00981481T patent/ES2258986T3/es not_active Expired - Lifetime
- 2000-12-12 JP JP2001548745A patent/JP2003518388A/ja active Pending
- 2000-12-12 CZ CZ20022193A patent/CZ298353B6/cs not_active IP Right Cessation
- 2000-12-12 WO PCT/GB2000/004767 patent/WO2001048233A1/en active IP Right Grant
- 2000-12-12 CA CA002395454A patent/CA2395454A1/en not_active Abandoned
- 2000-12-12 DE DE60026164T patent/DE60026164T2/de not_active Expired - Fee Related
- 2000-12-12 PT PT00981481T patent/PT1244805E/pt unknown
- 2000-12-12 AU AU18716/01A patent/AU781356B2/en not_active Ceased
- 2000-12-12 CN CNB008191468A patent/CN100354426C/zh not_active Expired - Fee Related
- 2000-12-12 UA UA2002076053A patent/UA77393C2/uk unknown
- 2000-12-12 AT AT00981481T patent/ATE318322T1/de not_active IP Right Cessation
- 2000-12-12 EP EP04077588A patent/EP1566445A3/en not_active Withdrawn
- 2000-12-12 RU RU2002119560/13A patent/RU2267536C2/ru not_active IP Right Cessation
-
2008
- 2008-10-30 US US12/261,999 patent/US20090209037A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CZ298353B6 (cs) | 2007-09-05 |
| EP1244805A1 (en) | 2002-10-02 |
| DE60026164D1 (de) | 2006-04-27 |
| EP1566445A3 (en) | 2005-08-31 |
| RU2267536C2 (ru) | 2006-01-10 |
| CN100354426C (zh) | 2007-12-12 |
| ES2258986T3 (es) | 2006-09-16 |
| CZ20022193A3 (cs) | 2003-02-12 |
| RU2002119560A (ru) | 2004-03-27 |
| AU1871601A (en) | 2001-07-09 |
| JP2003518388A (ja) | 2003-06-10 |
| CN1434870A (zh) | 2003-08-06 |
| CA2395454A1 (en) | 2001-07-05 |
| AU781356B2 (en) | 2005-05-19 |
| ATE318322T1 (de) | 2006-03-15 |
| WO2001048233A1 (en) | 2001-07-05 |
| PT1244805E (pt) | 2006-07-31 |
| GB9930533D0 (en) | 2000-02-16 |
| US20030153081A1 (en) | 2003-08-14 |
| EP1244805B1 (en) | 2006-02-22 |
| US20090209037A1 (en) | 2009-08-20 |
| DE60026164T2 (de) | 2006-11-16 |
| DK1244805T3 (da) | 2006-06-26 |
| EP1566445A2 (en) | 2005-08-24 |
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