UA75322C2 - Use of mhc class ii ligands as adjuvant for vaccination and lag-3 for cancer immunotherapy - Google Patents
Use of mhc class ii ligands as adjuvant for vaccination and lag-3 for cancer immunotherapy Download PDFInfo
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- UA75322C2 UA75322C2 UA2000020976A UA2000020976A UA75322C2 UA 75322 C2 UA75322 C2 UA 75322C2 UA 2000020976 A UA2000020976 A UA 2000020976A UA 2000020976 A UA2000020976 A UA 2000020976A UA 75322 C2 UA75322 C2 UA 75322C2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97401800A EP0893507A1 (en) | 1997-07-25 | 1997-07-25 | Use of MHC class II ligands (CD4 and LAG-3) as adjuvant for vaccination and of LAG-3 in cancer treatment |
| PCT/EP1998/004621 WO1999004810A2 (en) | 1997-07-25 | 1998-07-23 | Use of mhc class ii ligands as adjuvant for vaccination and of lag-3 in cancer treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75322C2 true UA75322C2 (en) | 2006-04-17 |
Family
ID=8229825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2000020976A UA75322C2 (en) | 1997-07-25 | 1998-07-23 | Use of mhc class ii ligands as adjuvant for vaccination and lag-3 for cancer immunotherapy |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6410509B1 (da) |
| EP (3) | EP0893507A1 (da) |
| JP (1) | JP4723722B2 (da) |
| KR (1) | KR100603075B1 (da) |
| CN (1) | CN1184320C (da) |
| AT (2) | ATE478956T1 (da) |
| AU (1) | AU753738B2 (da) |
| BR (1) | BR9811037A (da) |
| CA (2) | CA2293805C (da) |
| DE (2) | DE69841866D1 (da) |
| DK (1) | DK1002108T3 (da) |
| EA (3) | EA003740B1 (da) |
| EE (1) | EE200000039A (da) |
| ES (1) | ES2262242T3 (da) |
| IL (2) | IL134212A0 (da) |
| NO (1) | NO20000378L (da) |
| PT (1) | PT1002108E (da) |
| UA (1) | UA75322C2 (da) |
| WO (1) | WO1999004810A2 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1295895B1 (en) * | 2001-09-19 | 2011-08-10 | Institut Gustave Roussy | Peptides and proteins binding to glu-pro motifs, therapeutical compositions containing the same and applications thereof |
| PL1897548T5 (pl) * | 2003-02-28 | 2025-03-17 | The Johns Hopkins University | Regulacja komórek T |
| KR20050082389A (ko) * | 2004-02-18 | 2005-08-23 | 메덱스젠 주식회사 | 직렬 연쇄체를 갖는 면역접합체를 포함하는 장기이식합병증 치료용 약제학적 조성물 |
| FR2868781B1 (fr) * | 2004-04-13 | 2008-02-22 | Immutep | Composition de vaccin comprenant un ligand cmh de classe ii couple a un antigene, procede de preparation et utilisations |
| EP1777523A1 (en) * | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| EP2044949A1 (en) * | 2007-10-05 | 2009-04-08 | Immutep | Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response |
| WO2011031139A1 (en) | 2009-09-09 | 2011-03-17 | Universiteit Utrecht Holding B.V. | An ataq protein or a part thereof as a vaccine |
| SA110310855B1 (ar) | 2009-11-13 | 2014-09-16 | Laboratories Leti S L Unipersonal | استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي |
| MX345739B (es) | 2010-11-10 | 2017-02-14 | Laboratorios Leti S L * | Nuevo adyuvante. |
| GB201322626D0 (en) | 2013-12-19 | 2014-02-05 | Immutep S A | Combined preparations for the treatment of cancer |
| US9683048B2 (en) | 2014-01-24 | 2017-06-20 | Novartis Ag | Antibody molecules to PD-1 and uses thereof |
| CN103751778B (zh) * | 2014-01-28 | 2016-09-28 | 复旦大学 | 3′-脱氧腺苷在制备广谱疫苗增效的免疫佐剂中的应用 |
| JP6576962B2 (ja) | 2014-03-14 | 2019-09-18 | ノバルティス アーゲー | Lag−3に対する抗体分子およびその使用 |
| JP6423889B2 (ja) | 2014-10-07 | 2018-11-14 | サイトリミック株式会社 | Hsp70由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法 |
| WO2016094639A1 (en) * | 2014-12-10 | 2016-06-16 | Wisconsin Alumni Research Foundation | Mini-intronic plasmid dna vaccines in combination with lag3 blockade |
| GB201500374D0 (en) * | 2015-01-09 | 2015-02-25 | Immutep S A | Combined preparations for the treatment of cancer |
| WO2016143816A1 (ja) | 2015-03-09 | 2016-09-15 | 日本電気株式会社 | Gpc3由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法 |
| JP6311094B2 (ja) | 2015-04-07 | 2018-04-18 | サイトリミック株式会社 | 医薬 |
| JP6925980B2 (ja) | 2015-05-13 | 2021-08-25 | アジェナス インコーポレイテッド | がんの処置および予防のためのワクチン |
| EP3322431A2 (en) | 2015-07-16 | 2018-05-23 | Biokine Therapeutics Ltd. | Compositions and methods for treating cancer |
| US10265379B2 (en) | 2015-09-16 | 2019-04-23 | Annabelle Rodriguez Oquendo | Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for cardiovascular disease and other chronic inflammatory diseases |
| WO2017046409A1 (en) | 2015-09-18 | 2017-03-23 | Rijksuniversiteit Groningen | Long chain inulin for stimulating an immune response |
| ES2972560T3 (es) | 2016-10-11 | 2024-06-13 | Nec Corp | Medicamento que comprende un agonista de receptores tipo Toll, proteína LAG-3, un péptido derivado de HSP70 y un péptido derivado de GPC3 |
| CN108204958A (zh) * | 2016-12-19 | 2018-06-26 | 伊缪泰普有限公司 | 结合测定 |
| US11065317B2 (en) | 2018-04-26 | 2021-07-20 | Agenus Inc. | Heat shock protein-binding peptide compositions and methods of use thereof |
| CN113271970A (zh) * | 2018-09-27 | 2021-08-17 | 健诺西生物科学公司 | 治疗方法 |
| JP2020138940A (ja) | 2019-02-28 | 2020-09-03 | テルモ株式会社 | 治療方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ226414A (en) * | 1987-10-02 | 1992-07-28 | Genentech Inc | Cd4 peptide adhesion variants and their preparation and use |
| WO1990001870A1 (en) * | 1988-08-22 | 1990-03-08 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Retroviral vectors expressing soluble cd4; a gene therapy for aids |
| JPH02231083A (ja) * | 1988-08-31 | 1990-09-13 | Eisai Co Ltd | 組換ナチュラルキラー細胞活性化因子 |
| IL93599A0 (en) * | 1989-03-03 | 1990-12-23 | Microgenesys Inc | Kit and/or composition for the prevention or treatment of aids |
| EP0394827A1 (en) * | 1989-04-26 | 1990-10-31 | F. Hoffmann-La Roche Ag | Chimaeric CD4-immunoglobulin polypeptides |
| FR2656800B1 (fr) * | 1990-01-08 | 1992-05-15 | Roussy Inst Gustave | Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques. |
| US5851828A (en) * | 1991-03-07 | 1998-12-22 | The General Hospital Corporation | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
| PT681483E (pt) * | 1993-01-26 | 2005-11-30 | Wyeth Corp | Composicoes e metodos para distribuicao de material genetico |
| SE510135C2 (sv) * | 1994-05-05 | 1999-04-19 | Berol Nobel Ab | Vattenhaltig suspension av en cellulosaeter, sätt för dess framställning samt komposition |
| PT758383E (pt) * | 1994-05-06 | 2007-05-31 | Roussy Inst Gustave | Fracções polipeptídicas solúveis da ptroteína lag-3; processo de produção; composição terapêutica; anticorpos anti-idiotipo |
| JPH10503654A (ja) * | 1994-08-05 | 1998-04-07 | ワーナー−ランバート・コンパニー | レトロウイルスの感染の治療におけるトランスドミナント・ネガティブ・レトロウイルス・インテグラーゼの使用方法 |
| EP0787151A1 (en) * | 1994-12-07 | 1997-08-06 | F. Hoffmann-La Roche Ag | Monoclonal antibody fragments having immunosuppressant activity |
| CZ186897A3 (cs) * | 1994-12-23 | 1998-03-18 | Laboratoires Om S. A. | Použití molekul, schopných vázat MHC-II nebo napodobujících MHC-II pro výrobu farmaceutického prostředku |
| EP0869803B1 (en) * | 1995-12-28 | 2003-04-16 | The Johns Hopkins University School Of Medicine | Allogeneic paracrine cytokine tumor vaccines |
-
1997
- 1997-07-25 EP EP97401800A patent/EP0893507A1/en not_active Withdrawn
-
1998
- 1998-07-23 UA UA2000020976A patent/UA75322C2/uk unknown
- 1998-07-23 AT AT06008545T patent/ATE478956T1/de not_active IP Right Cessation
- 1998-07-23 EA EA200000161A patent/EA003740B1/ru not_active IP Right Cessation
- 1998-07-23 CN CNB988075474A patent/CN1184320C/zh not_active Expired - Lifetime
- 1998-07-23 EP EP98945090A patent/EP1002108B1/en not_active Expired - Lifetime
- 1998-07-23 JP JP2000503862A patent/JP4723722B2/ja not_active Expired - Lifetime
- 1998-07-23 AU AU92547/98A patent/AU753738B2/en not_active Expired
- 1998-07-23 CA CA2293805A patent/CA2293805C/en not_active Expired - Lifetime
- 1998-07-23 IL IL13421298A patent/IL134212A0/xx unknown
- 1998-07-23 EA EA200300092A patent/EA200300092A1/ru unknown
- 1998-07-23 DE DE69841866T patent/DE69841866D1/de not_active Expired - Lifetime
- 1998-07-23 DE DE69834330T patent/DE69834330T2/de not_active Expired - Lifetime
- 1998-07-23 KR KR1020007000265A patent/KR100603075B1/ko not_active Expired - Fee Related
- 1998-07-23 EP EP06008545A patent/EP1698701B1/en not_active Expired - Lifetime
- 1998-07-23 AT AT98945090T patent/ATE324455T1/de active
- 1998-07-23 WO PCT/EP1998/004621 patent/WO1999004810A2/en not_active Ceased
- 1998-07-23 EA EA200200565A patent/EA005405B1/ru not_active IP Right Cessation
- 1998-07-23 BR BR9811037-3A patent/BR9811037A/pt not_active IP Right Cessation
- 1998-07-23 CA CA2732570A patent/CA2732570C/en not_active Expired - Lifetime
- 1998-07-23 ES ES98945090T patent/ES2262242T3/es not_active Expired - Lifetime
- 1998-07-23 EE EEP200000039A patent/EE200000039A/xx unknown
- 1998-07-23 DK DK98945090T patent/DK1002108T3/da active
- 1998-07-23 PT PT98945090T patent/PT1002108E/pt unknown
-
2000
- 2000-01-24 IL IL134212A patent/IL134212A/en not_active IP Right Cessation
- 2000-01-25 NO NO20000378A patent/NO20000378L/no not_active Application Discontinuation
- 2000-01-27 US US09/492,113 patent/US6410509B1/en not_active Expired - Lifetime
-
2002
- 2002-01-10 US US10/041,600 patent/US7109026B2/en not_active Expired - Fee Related
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