UA73269C2 - A culture of competitive exception for reducing entero pathogenic bacteria prepared from livestock mucous membrane - Google Patents
A culture of competitive exception for reducing entero pathogenic bacteria prepared from livestock mucous membrane Download PDFInfo
- Publication number
- UA73269C2 UA73269C2 UA99052610A UA99052610A UA73269C2 UA 73269 C2 UA73269 C2 UA 73269C2 UA 99052610 A UA99052610 A UA 99052610A UA 99052610 A UA99052610 A UA 99052610A UA 73269 C2 UA73269 C2 UA 73269C2
- Authority
- UA
- Ukraine
- Prior art keywords
- culture
- specified
- scraping
- livestock
- composition
- Prior art date
Links
- 230000000369 enteropathogenic effect Effects 0.000 title claims abstract description 22
- 244000144972 livestock Species 0.000 title claims abstract description 17
- 230000002860 competitive effect Effects 0.000 title claims description 15
- 210000004400 mucous membrane Anatomy 0.000 title claims description 11
- 244000052616 bacterial pathogen Species 0.000 title description 2
- 241001465754 Metazoa Species 0.000 claims abstract description 59
- 238000007790 scraping Methods 0.000 claims abstract description 23
- 241000894006 Bacteria Species 0.000 claims abstract description 22
- 210000004534 cecum Anatomy 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 19
- 238000005406 washing Methods 0.000 claims description 17
- 241000252983 Caecum Species 0.000 claims description 13
- 230000007717 exclusion Effects 0.000 claims description 12
- 244000005706 microflora Species 0.000 claims description 10
- 241000283690 Bos taurus Species 0.000 claims description 7
- 235000010469 Glycine max Nutrition 0.000 claims description 7
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 7
- 230000001717 pathogenic effect Effects 0.000 claims description 6
- 239000002054 inoculum Substances 0.000 claims description 5
- 244000052769 pathogen Species 0.000 claims description 5
- 241000124008 Mammalia Species 0.000 claims description 4
- 210000002919 epithelial cell Anatomy 0.000 claims description 4
- 238000011081 inoculation Methods 0.000 claims description 3
- 244000068988 Glycine max Species 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims 2
- 238000011010 flushing procedure Methods 0.000 claims 1
- 210000004877 mucosa Anatomy 0.000 claims 1
- 238000012876 topography Methods 0.000 claims 1
- 241000607142 Salmonella Species 0.000 abstract description 21
- 238000002360 preparation method Methods 0.000 abstract description 7
- 241000589876 Campylobacter Species 0.000 abstract 1
- 241001646719 Escherichia coli O157:H7 Species 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 21
- 239000003814 drug Substances 0.000 description 21
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- 101000713585 Homo sapiens Tubulin beta-4A chain Proteins 0.000 description 3
- 102100036788 Tubulin beta-4A chain Human genes 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000003304 gavage Methods 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 210000002445 nipple Anatomy 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000006041 probiotic Substances 0.000 description 3
- 230000000529 probiotic effect Effects 0.000 description 3
- 235000018291 probiotics Nutrition 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 241000271566 Aves Species 0.000 description 2
- 206010039438 Salmonella Infections Diseases 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000000721 bacterilogical effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000034994 death Effects 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000000981 epithelium Anatomy 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 244000078673 foodborn pathogen Species 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 235000013594 poultry meat Nutrition 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 206010039447 salmonellosis Diseases 0.000 description 2
- 230000000405 serological effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- OFQCQIGMURIECL-UHFFFAOYSA-N 2-[2-(diethylamino)ethyl]-2',6'-dimethylspiro[isoquinoline-4,4'-oxane]-1,3-dione;phosphoric acid Chemical compound OP(O)(O)=O.O=C1N(CCN(CC)CC)C(=O)C2=CC=CC=C2C21CC(C)OC(C)C2 OFQCQIGMURIECL-UHFFFAOYSA-N 0.000 description 1
- 206010056519 Abdominal infection Diseases 0.000 description 1
- 244000003363 Allium ursinum Species 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000011293 Brassica napus Nutrition 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
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- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 206010022678 Intestinal infections Diseases 0.000 description 1
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 241000283903 Ovis aries Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
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- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000724822 Teia Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- JKKPSTXVKNWEAH-VWHZSNQBSA-N bbip Chemical compound NC(=N)NCCC[C@@H](C(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1N(C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)C=2C=CC(=CC=2)C(=O)C=2C=CC=CC=2)CCC1 JKKPSTXVKNWEAH-VWHZSNQBSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000005757 colony formation Effects 0.000 description 1
- 210000003022 colostrum Anatomy 0.000 description 1
- 235000021277 colostrum Nutrition 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 244000000036 gastrointestinal pathogen Species 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 150000005605 isobutyric acids Chemical class 0.000 description 1
- 229940015418 ketaset Drugs 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006194 liquid suspension Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229960000210 nalidixic acid Drugs 0.000 description 1
- MHWLWQUZZRMNGJ-UHFFFAOYSA-N nalidixic acid Chemical compound C1=C(C)N=C2N(CC)C=C(C(O)=O)C(=O)C2=C1 MHWLWQUZZRMNGJ-UHFFFAOYSA-N 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 210000002741 palatine tonsil Anatomy 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229940069575 rompun Drugs 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 238000009589 serological test Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229940052907 telazol Drugs 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- QYEFBJRXKKSABU-UHFFFAOYSA-N xylazine hydrochloride Chemical compound Cl.CC1=CC=CC(C)=C1NC1=NCCCS1 QYEFBJRXKKSABU-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/729,113 US5807546A (en) | 1996-10-11 | 1996-10-11 | Livestock mucosal competitive exclusion culture to reduce enteropathogenic bacteria |
PCT/US1997/018769 WO1998016626A1 (en) | 1996-10-11 | 1997-10-10 | Livestock mucosal competitive exclusion culture to reduce enteropathogenic bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
UA73269C2 true UA73269C2 (en) | 2005-07-15 |
Family
ID=24929644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA99052610A UA73269C2 (en) | 1996-10-11 | 1997-10-10 | A culture of competitive exception for reducing entero pathogenic bacteria prepared from livestock mucous membrane |
Country Status (12)
Country | Link |
---|---|
US (2) | US5807546A (cs) |
EP (1) | EP0932661A4 (cs) |
JP (1) | JP2002503084A (cs) |
CN (2) | CN1233285A (cs) |
AU (1) | AU738730B2 (cs) |
BR (1) | BR9712252A (cs) |
CA (1) | CA2267233A1 (cs) |
CZ (1) | CZ294683B6 (cs) |
HU (1) | HUP0000148A3 (cs) |
PL (1) | PL189717B1 (cs) |
UA (1) | UA73269C2 (cs) |
WO (1) | WO1998016626A1 (cs) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5951977A (en) * | 1997-10-14 | 1999-09-14 | The United States Of America, As Represented By The Secretary Of Agriculture | Competitive exclusion culture for swine |
CA2414941C (en) | 2000-08-11 | 2010-12-14 | David R. Whitlock | Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same |
WO2003057380A2 (en) * | 2002-01-11 | 2003-07-17 | Whitlock David R | Compositions including ammonia oxidizing bacteria and methods of using same |
WO2004000335A1 (en) | 2002-06-19 | 2003-12-31 | The Board Of Regents Of The University Of Nebraska | Lactic acid bacteria cultures that inhibit food-borne pathogens |
US20040241150A1 (en) * | 2002-12-19 | 2004-12-02 | Hargis Billy M. | Defined competitive exclusion cultures for food borne pathogens |
WO2004104175A2 (en) * | 2003-05-14 | 2004-12-02 | University Of Georgia Research Foundation, Inc. | Probiotic bacteria and methods |
CA2539974A1 (en) * | 2003-09-26 | 2005-04-07 | David R. Whitlock | Methods of using ammonia oxidizing bacteria |
US20060039899A1 (en) * | 2004-08-23 | 2006-02-23 | Winn Robert T | Animal nutritional product that increases weight gain and reduces diarrhea morbidity, mortality and severity by stimulation of natural immune response, nutritional support of immune function and supplemental nutricines and probiotics |
US9005601B2 (en) | 2010-07-16 | 2015-04-14 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
WO2014022572A1 (en) | 2012-08-01 | 2014-02-06 | Pacific Vet Group-Usa, Inc. | Probiotic for amelioration of coccidiosis vaccine reaction |
US11225640B2 (en) | 2014-04-15 | 2022-01-18 | Aobiome Llc | Ammonia oxidizing bacteria for treatment of psoriasis |
KR20230165365A (ko) | 2014-04-15 | 2023-12-05 | 에이오바이오미 엘엘씨 | 암모니아-산화 니트로소모나스 유트로파 균주 d23 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4335107A (en) * | 1978-06-05 | 1982-06-15 | Snoeyenbos Glenn H | Mixture to protect poultry from salmonella |
FI840816A0 (fi) * | 1984-03-01 | 1984-03-01 | Farmos Oy | Bakteriepreparat |
US4910024A (en) * | 1988-07-05 | 1990-03-20 | Micro Chemical, Inc. | Method and apparatus for administering live bacteria as feed additives to livestock and poultry |
US5206015A (en) * | 1989-06-05 | 1993-04-27 | The United States Of America As Represented By The Secretary Of Agriculture | Introduction of bacteria in ovo |
US5478557A (en) * | 1992-07-29 | 1995-12-26 | The United States Of America, As Represented By The Secretary Of Agriculture | Probiotic for control of salmonella |
CA2156486C (en) * | 1993-03-16 | 2002-11-12 | Norman J. Stern | Mucosal competitive exclusion flora |
GB2298432B (en) * | 1995-03-03 | 1999-04-14 | Orion Yhtymae Oy | In ovo administration of a competitive exclusion culture |
-
1996
- 1996-10-11 US US08/729,113 patent/US5807546A/en not_active Expired - Fee Related
-
1997
- 1997-10-10 AU AU49071/97A patent/AU738730B2/en not_active Ceased
- 1997-10-10 CA CA002267233A patent/CA2267233A1/en not_active Abandoned
- 1997-10-10 JP JP51861398A patent/JP2002503084A/ja not_active Ceased
- 1997-10-10 HU HU0000148A patent/HUP0000148A3/hu unknown
- 1997-10-10 BR BR9712252-1A patent/BR9712252A/pt not_active Application Discontinuation
- 1997-10-10 CN CN97198680A patent/CN1233285A/zh active Pending
- 1997-10-10 WO PCT/US1997/018769 patent/WO1998016626A1/en not_active Application Discontinuation
- 1997-10-10 CN CNA031077617A patent/CN1515667A/zh active Pending
- 1997-10-10 EP EP97911774A patent/EP0932661A4/en not_active Withdrawn
- 1997-10-10 CZ CZ19991200A patent/CZ294683B6/cs not_active IP Right Cessation
- 1997-10-10 UA UA99052610A patent/UA73269C2/uk unknown
- 1997-10-10 PL PL97332621A patent/PL189717B1/pl not_active IP Right Cessation
-
1998
- 1998-06-26 US US09/105,306 patent/US6214335B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0932661A4 (en) | 2000-08-23 |
CN1233285A (zh) | 1999-10-27 |
US6214335B1 (en) | 2001-04-10 |
CZ294683B6 (cs) | 2005-02-16 |
HUP0000148A3 (en) | 2001-09-28 |
EP0932661A1 (en) | 1999-08-04 |
HUP0000148A2 (hu) | 2000-06-28 |
WO1998016626A1 (en) | 1998-04-23 |
AU4907197A (en) | 1998-05-11 |
CN1515667A (zh) | 2004-07-28 |
AU738730B2 (en) | 2001-09-27 |
CZ120099A3 (cs) | 1999-07-14 |
PL332621A1 (en) | 1999-09-27 |
CA2267233A1 (en) | 1998-04-23 |
JP2002503084A (ja) | 2002-01-29 |
BR9712252A (pt) | 2000-01-25 |
US5807546A (en) | 1998-09-15 |
PL189717B1 (pl) | 2005-09-30 |
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