UA128783C2 - Т-клітини зі зниженим поверхневим фукозилуванням і способи їх отримання і застосування - Google Patents
Т-клітини зі зниженим поверхневим фукозилуванням і способи їх отримання і застосування Download PDFInfo
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- UA128783C2 UA128783C2 UAA201912290A UAA201912290A UA128783C2 UA 128783 C2 UA128783 C2 UA 128783C2 UA A201912290 A UAA201912290 A UA A201912290A UA A201912290 A UAA201912290 A UA A201912290A UA 128783 C2 UA128783 C2 UA 128783C2
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- surface fucosylation
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/23—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Hematology (AREA)
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- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
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| US201762516536P | 2017-06-07 | 2017-06-07 | |
| PCT/US2018/036067 WO2018226701A1 (en) | 2017-06-07 | 2018-06-05 | T cells with reduced surface fucosylation and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
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| UA128783C2 true UA128783C2 (uk) | 2024-10-23 |
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| UAA201912290A UA128783C2 (uk) | 2017-06-07 | 2018-06-05 | Т-клітини зі зниженим поверхневим фукозилуванням і способи їх отримання і застосування |
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| WO (1) | WO2018226701A1 (enExample) |
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| US12036286B2 (en) | 2021-03-18 | 2024-07-16 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| WO2022221766A1 (en) * | 2021-04-16 | 2022-10-20 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Fucosylation and immune modulation in cancer |
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| WO2012019165A2 (en) * | 2010-08-05 | 2012-02-09 | Seattle Genetics, Inc. | Methods of inhibition of protein fucosylation in vivo using fucose analogs |
| WO2012177925A1 (en) | 2011-06-21 | 2012-12-27 | The Board Institute, Inc. | Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene |
| PT3102609T (pt) | 2014-02-04 | 2024-10-23 | Us Health | Métodos de produção de células t autólogas úteis para o tratamento de malignidades das células b e de outros cancros e respetivas composições |
| US11400115B2 (en) | 2014-04-23 | 2022-08-02 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| MX2017000646A (es) | 2014-07-15 | 2017-04-27 | Juno Therapeutics Inc | Celulas geneticamente modificadas para terapia celular adoptiva. |
| MX2017003062A (es) | 2014-09-09 | 2017-12-14 | Unum Therapeutics | Receptores quimericos y usos de los mismos en terapia inmune. |
| EP3227323B1 (en) | 2014-12-03 | 2020-08-05 | Juno Therapeutics, Inc. | Methods and compositions for adoptive cell therapy |
| IL292504B2 (en) | 2015-10-20 | 2024-01-01 | Kite Pharma Inc | Methods of preparing T cells for T cell therapy |
| SG11201804263PA (en) * | 2015-12-04 | 2018-06-28 | Seattle Genetics Inc | Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor |
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| CN110740734A (zh) | 2020-01-31 |
| JP7245177B2 (ja) | 2023-03-23 |
| CA3065524A1 (en) | 2018-12-13 |
| US20240117400A1 (en) | 2024-04-11 |
| EP3634427A1 (en) | 2020-04-15 |
| IL271012B2 (en) | 2023-12-01 |
| MX2019014584A (es) | 2020-02-07 |
| JP2020523014A (ja) | 2020-08-06 |
| US11891644B2 (en) | 2024-02-06 |
| EA201992875A1 (ru) | 2020-03-25 |
| WO2018226701A1 (en) | 2018-12-13 |
| KR20200015580A (ko) | 2020-02-12 |
| TW201903144A (zh) | 2019-01-16 |
| MA50865A (fr) | 2020-04-15 |
| ZA201907623B (en) | 2024-04-24 |
| US20200149082A1 (en) | 2020-05-14 |
| KR102687149B1 (ko) | 2024-07-24 |
| SG11201911617SA (en) | 2020-01-30 |
| IL271012A (en) | 2020-01-30 |
| BR112019025775A2 (pt) | 2020-06-23 |
| AU2018282225A1 (en) | 2019-12-12 |
| AU2018282225B2 (en) | 2024-06-13 |
| IL271012B1 (en) | 2023-08-01 |
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