JP7245177B2 - 低減した表面フコシル化を有するｔ細胞、及びそれを作製及び使用する方法 - Google Patents

低減した表面フコシル化を有するｔ細胞、及びそれを作製及び使用する方法 Download PDF

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JP7245177B2
JP7245177B2 JP2019567708A JP2019567708A JP7245177B2 JP 7245177 B2 JP7245177 B2 JP 7245177B2 JP 2019567708 A JP2019567708 A JP 2019567708A JP 2019567708 A JP2019567708 A JP 2019567708A JP 7245177 B2 JP7245177 B2 JP 7245177B2
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cancer
cell
fucose
pharmaceutical composition
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オークリー，ニコル
フィールド，ジェシカ
ガーダイ，シャイラ
ハイザー，ライアン
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シージェン インコーポレイテッド
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JP2019567708A 2017-06-07 2018-06-05 低減した表面フコシル化を有するｔ細胞、及びそれを作製及び使用する方法 Active JP7245177B2 (ja)

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US201762516536P 2017-06-07 2017-06-07
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PCT/US2018/036067 WO2018226701A1 (en) 2017-06-07 2018-06-05 T cells with reduced surface fucosylation and methods of making and using the same

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CN (1) CN110740734A (enExample)
AU (1) AU2018282225B2 (enExample)
BR (1) BR112019025775A2 (enExample)
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IL (1) IL271012B2 (enExample)
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WO2021034774A1 (en) * 2019-08-16 2021-02-25 H. Lee Moffitt Cancer Center And Research Institute, Inc. Fucosylation and immune modulation in cancer
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
WO2022221766A1 (en) * 2021-04-16 2022-10-20 H. Lee Moffitt Cancer Center And Research Institute, Inc. Fucosylation and immune modulation in cancer

Citations (2)

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JP2013541503A (ja) 2010-08-05 2013-11-14 シアトル ジェネティクス，インコーポレーテッド フコースアナログを用いるイン・ビボでのタンパク質フコシル化の阻害方法
JP2019501145A (ja) 2015-12-04 2019-01-17 シアトル ジェネティクス，インコーポレーテッド チェックポイント阻害剤と組みわせて２−デオキシ−２−フルオロ−ｌ−フコースを用いる癌治療

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
WO2012177925A1 (en) 2011-06-21 2012-12-27 The Board Institute, Inc. Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene
PT3102609T (pt) 2014-02-04 2024-10-23 Us Health Métodos de produção de células t autólogas úteis para o tratamento de malignidades das células b e de outros cancros e respetivas composições
US11400115B2 (en) 2014-04-23 2022-08-02 Juno Therapeutics, Inc. Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
MX2017000646A (es) 2014-07-15 2017-04-27 Juno Therapeutics Inc Celulas geneticamente modificadas para terapia celular adoptiva.
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JP2019501145A (ja) 2015-12-04 2019-01-17 シアトル ジェネティクス，インコーポレーテッド チェックポイント阻害剤と組みわせて２−デオキシ−２−フルオロ−ｌ−フコースを用いる癌治療

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Alley, S. C. et al.，Abstract DDT02-02: SGN-2FF: A novel small molecule inhibitor of fucosylation with preclinical antitumor antivity through multiple immune mechanisms，Cancer Res，2017年04月01日，７７（１３＿Supplement），DDT02-02
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CN110740734A (zh) 2020-01-31
CA3065524A1 (en) 2018-12-13
US20240117400A1 (en) 2024-04-11
EP3634427A1 (en) 2020-04-15
IL271012B2 (en) 2023-12-01
MX2019014584A (es) 2020-02-07
JP2020523014A (ja) 2020-08-06
US11891644B2 (en) 2024-02-06
EA201992875A1 (ru) 2020-03-25
WO2018226701A1 (en) 2018-12-13
KR20200015580A (ko) 2020-02-12
TW201903144A (zh) 2019-01-16
MA50865A (fr) 2020-04-15
ZA201907623B (en) 2024-04-24
US20200149082A1 (en) 2020-05-14
KR102687149B1 (ko) 2024-07-24
SG11201911617SA (en) 2020-01-30
IL271012A (en) 2020-01-30
UA128783C2 (uk) 2024-10-23
BR112019025775A2 (pt) 2020-06-23
AU2018282225A1 (en) 2019-12-12
AU2018282225B2 (en) 2024-06-13
IL271012B1 (en) 2023-08-01

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