UA126882C2 - Застосування ly3154207 при лікуванні дофамінергічних порушень цнс - Google Patents

Застосування ly3154207 при лікуванні дофамінергічних порушень цнс Download PDF

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Publication number
UA126882C2
UA126882C2 UAA202103923A UAA202103923A UA126882C2 UA 126882 C2 UA126882 C2 UA 126882C2 UA A202103923 A UAA202103923 A UA A202103923A UA A202103923 A UAA202103923 A UA A202103923A UA 126882 C2 UA126882 C2 UA 126882C2
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UA
Ukraine
Prior art keywords
dose
pharmaceutical composition
per day
patient
administration
Prior art date
Application number
UAA202103923A
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English (en)
Ukrainian (uk)
Inventor
Кевін Майкл Біглан
Кевин Майкл Биглан
Крістіна Марі Кайлі
Кристина Мари Кайли
К'єлль Андерс Іван Свенссон
Кьелль Андерс Иван Свенссон
Original Assignee
Елі Ліллі Енд Компані
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Елі Ліллі Енд Компані, Эли Лилли Энд Компани filed Critical Елі Ліллі Енд Компані
Publication of UA126882C2 publication Critical patent/UA126882C2/uk

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UAA202103923A 2018-12-18 2019-12-16 Застосування ly3154207 при лікуванні дофамінергічних порушень цнс UA126882C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862781251P 2018-12-18 2018-12-18
US201962904048P 2019-09-23 2019-09-23
PCT/US2019/066465 WO2020131671A1 (en) 2018-12-18 2019-12-16 Dose regimens for use of ly3154207 in the treatment of dopaminergic cns disorders

Publications (1)

Publication Number Publication Date
UA126882C2 true UA126882C2 (uk) 2023-02-15

Family

ID=69167914

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA202103923A UA126882C2 (uk) 2018-12-18 2019-12-16 Застосування ly3154207 при лікуванні дофамінергічних порушень цнс

Country Status (15)

Country Link
US (1) US20220062265A1 (ja)
EP (2) EP4417258A2 (ja)
JP (2) JP2022514659A (ja)
KR (1) KR20210111783A (ja)
CN (1) CN113347961A (ja)
AU (1) AU2019402087B2 (ja)
BR (1) BR112021012102A2 (ja)
CA (1) CA3124416C (ja)
IL (1) IL284175A (ja)
MA (1) MA54530A (ja)
MX (1) MX2021007442A (ja)
SG (1) SG11202106595VA (ja)
TW (2) TW202423437A (ja)
UA (1) UA126882C2 (ja)
WO (1) WO2020131671A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240299375A1 (en) * 2021-03-08 2024-09-12 Eli Lilly And Company Use of mevidalen and other d1 positive allosteric modulators in the treatment of hallucinations and dementia-related psychosis
WO2022192255A1 (en) * 2021-03-09 2022-09-15 Eli Lilly And Company Use of mevidalen and other d1 positive allosteric modulators for slowing of parkinson's disease progression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3316B1 (ar) 2013-05-30 2019-03-13 Lilly Co Eli مركبات 3، 4-داي هيدرو أيزو كوينولين -2(1h)-يل
AR106332A1 (es) 2015-10-23 2018-01-03 Lilly Co Eli Forma cristalina de 2-(2,6-diclorofenil)-1-[(1s,3r)-3-(hidroximetil)-5-(3-hidroxi-3-metilbutil)-1-metil-3,4-dihidroisoquinolin-2(1h)-il]etanona

Also Published As

Publication number Publication date
BR112021012102A2 (pt) 2021-09-08
IL284175A (en) 2021-08-31
TWI831896B (zh) 2024-02-11
MA54530A (fr) 2021-10-27
SG11202106595VA (en) 2021-07-29
JP2022514659A (ja) 2022-02-14
CA3124416C (en) 2023-05-23
MX2021007442A (es) 2021-10-01
TW202038955A (zh) 2020-11-01
US20220062265A1 (en) 2022-03-03
EP3897578A1 (en) 2021-10-27
WO2020131671A1 (en) 2020-06-25
TW202423437A (zh) 2024-06-16
AU2019402087A1 (en) 2021-07-15
KR20210111783A (ko) 2021-09-13
AU2019402087B2 (en) 2023-04-06
JP2023055770A (ja) 2023-04-18
CN113347961A (zh) 2021-09-03
EP4417258A2 (en) 2024-08-21
CA3124416A1 (en) 2020-06-25

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