UA124622C2 - Кон'юговані імуноглобуліни з c-кінцевим лізином - Google Patents

Кон'юговані імуноглобуліни з c-кінцевим лізином Download PDF

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Publication number
UA124622C2
UA124622C2 UAA201807950A UAA201807950A UA124622C2 UA 124622 C2 UA124622 C2 UA 124622C2 UA A201807950 A UAA201807950 A UA A201807950A UA A201807950 A UAA201807950 A UA A201807950A UA 124622 C2 UA124622 C2 UA 124622C2
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UA
Ukraine
Prior art keywords
amino acid
terminal lysine
acid residue
immunoglobulin
residue
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UAA201807950A
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English (en)
Ukrainian (uk)
Inventor
Джаред Спайдел
Ерл Елбон
Эрл ЭЛБОН
Original Assignee
ЕЙСАЙ Ар ЕНД Ді МЕНЕДЖМЕНТ КО., ЛТД.
Эйсай Ар Энд Ди Менеджмент Ко., Лтд.
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Publication of UA124622C2 publication Critical patent/UA124622C2/uk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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