UA107818C2 - Alkyl amino pyrimidine derivatives as antagonists district h4-histamine receptors - Google Patents
Alkyl amino pyrimidine derivatives as antagonists district h4-histamine receptors Download PDFInfo
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- UA107818C2 UA107818C2 UAA201207986A UAA201207986A UA107818C2 UA 107818 C2 UA107818 C2 UA 107818C2 UA A201207986 A UAA201207986 A UA A201207986A UA A201207986 A UAA201207986 A UA A201207986A UA 107818 C2 UA107818 C2 UA 107818C2
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- alkyl
- formula
- compounds
- methyl
- group
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- 125000003282 alkyl amino group Chemical group 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 description 418
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07—ORGANIC CHEMISTRY
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
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- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Neurology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09382302 | 2009-12-23 | ||
| PCT/EP2010/070562 WO2011076878A1 (en) | 2009-12-23 | 2010-12-22 | Aminoalkylpyrimidine derivatives as histamine h4 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA107818C2 true UA107818C2 (en) | 2015-02-25 |
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| UAA201207986A UA107818C2 (en) | 2009-12-23 | 2010-12-22 | Alkyl amino pyrimidine derivatives as antagonists district h4-histamine receptors |
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| PH12021552978A1 (en) * | 2011-09-02 | 2022-08-22 | Incyte Holdings Corp | Heterocyclylamines as pi3k inhibitors |
| TWI797176B (zh) | 2017-10-17 | 2023-04-01 | 西班牙商帕羅製藥有限公司 | ４-胺基嘧啶化合物之合成 |
| GB201817047D0 (en) | 2018-10-19 | 2018-12-05 | Heptares Therapeutics Ltd | H4 antagonist compounds |
| JP2022165429A (ja) * | 2019-10-02 | 2022-11-01 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ヒスタミンｈ４受容体調節作用を有する新規トリアジン誘導体 |
| CN117018194A (zh) * | 2023-07-26 | 2023-11-10 | 同济大学 | 毒蕈碱型受体5型受体拮抗剂的用途 |
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| EP1562935B1 (de) * | 2002-10-28 | 2006-09-06 | Bayer HealthCare AG | Heteroaryloxy-substituierte phenylaminopyrimidine als rho-kinaseinhibitoren |
| US7494987B2 (en) * | 2002-11-25 | 2009-02-24 | Mochida Pharmaceutical Co., Ltd. | Agent for treating respiratory diseases containing 4-hydroxypiperidine derivative as active ingredient |
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| CL2008000467A1 (es) | 2007-02-14 | 2008-08-22 | Janssen Pharmaceutica Nv | Compuestos derivados de 2-aminopirimidina, moduladores del receptor histamina h4; su procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno inflamatorio seleccionado de alegia, asma |
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| RU2012131223A (ru) | 2014-02-10 |
| EP2516420B8 (en) | 2018-10-17 |
| US20130018031A1 (en) | 2013-01-17 |
| WO2011076878A1 (en) | 2011-06-30 |
| CN102803248A (zh) | 2012-11-28 |
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