TWM478483U - Antrodia cinnamomea powder capsule structure for suppressing growth and proliferation of tumor cells of colorectal cancer - Google Patents

Description

Microcapsule powder capsule structure for inhibiting growth and proliferation of colorectal cancer tumor cells

This creation relates to the technical field of a capsule structure that can embed powder.

Antrodia camphorata, also known as Antrodia camphorata or Burdock mushroom, belongs to the fungi community (Fungi), Basidiomycota, Basidiomycotina, Homobasidiomycetes, and taxonomy. Aphyllophorales, Polyporaceae, Antrodia. The body of the burdock is grown on the inner wall of the heartwood of Taiwan's conservation burdock (Cirnamoum kanehirai Hay). The periphery is curved inward and can decompose the cellulose of the wood and cause the wood to decay. It is a decaying wood. The growth environment of wild Antrodia camphorata belongs to the dark, humid and low temperature middle altitude areas, especially the wild Antrodia camphora grows slowly, so it takes a long time to produce fruiting bodies. Because burdock is a kind of conservation tree species and the distribution is extremely rare, coupled with artificial piracy, the number of wild burdock is quite rare, making the burdock an expensive price, so it has the reputation of "the ruby in the forest".

The body of Ox sylvestris is perennial, sessile and cork-to-wood. It has a strong aroma of eucalyptus and has a variety of shapes. It has a plate shape, a bell shape, a horseshoe shape or a tower shape. It is close to the surface of the wood and has a pore shape on the surface of the mushroom. It is bright red at birth, and becomes milky white, reddish brown, light brown or yellowish brown with growth. The periphery is often radial and grows to the periphery, showing a semicircular or irregular shape. shape.

Some species of Antrodia camphorata have been found to have pharmacological activity. In Taiwan folk medicine therapy, the body of A. sylvestris is considered to have certain medical effects. The fruiting body is finely ground into a dry powder or taken orally in a boiled way, which is effective for folk circulation. The edible mushroom has the activities of detoxification, anti-inflammatory, anti-tumor, inhibition of vascular proliferation and treatment of liver diseases.

The large intestine consists of the cecum, colon and rectum, which are the last level of the human digestive system. Normal colorectal mucosa can cause benign tumors (ie, sputum) to proliferate in the inner wall of the large intestine due to many factors, and even further become colorectal cancer. Colorectal cancer, also known as colorectal cancer, is one of the most common malignant tumors in the world. In recent years, in Taiwan, due to the westernization and refinement of Chinese people's living and eating patterns, and animal fat and protein intake. The year-on-year increase and the diminishing consumption of dietary fiber have led to an increase in the incidence of colorectal cancer, which is now the third leading cause of cancer death.

The main symptoms of colorectal cancer include bloody stools, abnormal bowel movements, abdominal sensation, anemia, and even touching the abdominal lumps. Colorectal cancer is not easy to have symptoms when it occurs early, but when it has conscious symptoms, it is already a stage of non-early cancer, which causes difficulty in treatment. In addition, colorectal cancer generally occurs in patients over the age of 50, but studies have shown that the average age of colorectal cancer patients in Taiwan is lower than that of foreign countries, the trend of rejuvenation is obvious, and the prognosis of young people with colorectal cancer is relatively poor, this and young. Human cancer is usually associated with poorly differentiated, highly malignant cancers, and because young people's cancers are often associated with terminal cancer at the time of initial diagnosis.

The treatment of colorectal cancer is mainly based on surgical resection, and for patients with cancer cell proliferation, radiation therapy and chemotherapy are supplemented. One of the main effects of chemotherapy is to interfere with the progression of cancer cells, affecting the synthesis of DNA, RNA and proteins, and inhibiting tumors. For the purpose of cell proliferation, however, radiation therapy and chemotherapy are often accompanied by other side effects that cause physical discomfort; on the other hand, liver and lung are the sites most likely to produce distant metastasis of colorectal cancer. Even with combined chemotherapy and cancer cell target therapy, the results of most patients with distant metastases are limited and their prognosis is poor. Therefore, it is imperative to develop therapeutic substances with effective and low side effects for clinical application.

At present, many experiments have revealed that the body of A. angustifolia has anti-cancer effect, and its components are also analyzed. Therefore, it would be an urgent problem to provide a better treatment for these patients or to prevent colorectal cancer.

Therefore, in view of the above-mentioned lack of the above-mentioned derivatives, the creators of this case have improved and innovated, in addition to the development of a burdock powder, the active ingredient of which has the effect of inhibiting the growth and spread of colorectal cancer cells; in addition, with the capsule structure of the present invention, It is easy for the user to ingest enough of the Antrodia camphorata powder to treat or prevent colorectal cancer. Therefore, this article proposes a structure of a capsule of Astragalus membranaceus that inhibits the growth and spread of colorectal cancer cells.

The purpose of the present invention is to provide a capsule structure of Antrodia camphorata powder which inhibits the growth and spread of colorectal cancer tumor cells.

A second object of the present invention is to provide a capsule structure in which the active ingredient of the Antrodia camphorata powder can exert its effect on inhibiting the growth and spread of colorectal cancer tumor cells in a user.

A capsule structure for inhibiting the growth and spread of colorectal cancer tumor cells, comprising: a capsule, a protective layer, and a core; It is covered by the protective layer, which is then covered with a capsule.

The structure of the Antrodia camphorata powder capsule provided by the present invention can be preserved for a long time in addition to the contained Antrodia camphorata powder (and its active ingredient); in addition, the core of the Antrodia camphorata powder (and its active ingredient) can also inhibit the large intestine Cancer tumor cell growth and spread. The capsule structure provided by this creation can be easily taken by the user, so that it can be used in combination with other treatments in addition to daily health care.

1‧‧‧Capsule structure

11‧‧‧ capsule

12‧‧‧Protective layer

13‧‧‧ core

Figure 1 is a cross-sectional view showing the structure of an Antrodia camphorata powder capsule which inhibits the growth and spread of colorectal cancer tumor cells.

The present invention provides a structure of an Antrodia camphorata powder capsule which inhibits the growth and spread of colorectal cancer tumor cells, and is described in detail according to the present creation, and is referred to the first figure.

The present invention comprises a structure 1 for the growth and spread of colorectal cancer tumor cells, which comprises, in order from the outside to the inside, a capsule 11, a protective layer 12, and a core 13; the core 13 is protected by the protective layer 12 The coating, in addition to blocking the oxidation between the external environment and the core 13, can also be used to protect the active constituents of the Antrodia camphorata in the core 13 from being damaged by factors such as gastric acid. In addition, the protective layer 12 is further covered by a capsule 11 to protect the core 13 and the protective layer 12 from physical factors such as heavy pressure, spikes, and the like.

The components used in the capsule 11 include, but are not limited to, gelatin (Gelatin), methyl cellulose (Methyl cellulose), and hydroxypropyl methyl cellulose (Hydroxymethyl). Propyl cellulose), Hydroxymethyl propyl cellulose, Polyvinyl alcohol, Polyvinyl pyrrolidone, Cellulose acetate phthalate, Hydroxy phthalate Hydroxypropyl methylcellulose phthalate or other materials suitable for the present invention; wherein the gelatin may comprise animal gelatin (made from animal sources such as fish skin, pig skin, etc.) and vegetable gelatin (eg, hydroxypropyl) Methyl cellulose (HPMC)).

The protective layer 12 may include, but is not limited to, an excipient, a disintegrant, an enteric coating, a binder, a diluent, a coating agent, a swelling agent, a lubricant, a flavoring agent, a sweetener, a solubilizing agent. Or any combination thereof.

Wherein, the excipient may be a sugar, including lactose, sucrose, mannitol, sorbitol; the cellulose preparation is, for example, corn starch, wheat starch, rice starch, potato starch, gelatin, tragacanth, etc. or other Materials suitable for this creation; they can be used to increase the mouthfeel, support the overall structure, and protect the core 13.

The core 13 contains an Antrodia camphorata powder (active substance) which can be used to inhibit the growth and spread of colorectal cancer tumor cells. The Antrodia camphorata powder can be made from the fruit body of Antrodia camphorata.

The above-mentioned capsule structure 1 may also be suitably added with one or more kinds of preservatives, colorants, flavors and flavors or other additives suitable for the present invention which are commonly used in the field, so as to shape, preserve and color. Add flavor.

The above powder capsule structure can be prepared by taking it in a capsule for oral administration, or by taking it directly or by other forms suitable for the present invention.

The detailed description above is a detailed description of one of the possible implementations of the present invention, but the embodiment is not intended to limit the scope of the patent of the present invention. The equivalent implementation or change of God shall be included in the scope of the patent in this case.

In summary, the technical features disclosed in this case have fully met the statutory patent requirements for novelty, advancement and industrial applicability. If you apply in accordance with the law, you are requested to approve the new patent application for your invention. Will.

1‧‧‧Capsule structure

11‧‧‧ capsule

12‧‧‧Protective layer

13‧‧‧ core

Claims (5)

The structure of an Antrodia camphorata powder capsule for inhibiting the growth and spread of colorectal cancer tumor cells comprises: a capsule shell, a protective layer, and a core; the core layer is covered by the protective layer, and the protective layer is further Covered with a capsule. The capsule structure according to claim 1, wherein the composition of the capsule comprises gelatin, methylcellulose, hydroxypropylmethylcellulose, hydroxypropylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, Cellulose acetate phthalate, hydroxypropyl cellulose phthalate. The capsule structure according to claim 1, wherein the protective layer component comprises an excipient, a disintegrating agent, an enteric coating, a binder, a diluent, a coating agent, a swelling agent, a lubricant, and a seasoning. Agent, sweetener, solubilizer. The capsule structure of claim 3, wherein the component of the excipient comprises lactose, sucrose, mannitol, sorbitol, corn starch, wheat starch, rice starch, potato starch, gelatin, tragacanth. The capsule structure of claim 1, wherein the core comprises anthraquinone powder prepared from a body of A. nigra.