TWM478451U - Antrodia cinnamomea powder capsule structure for inhibiting lymphoma tumor cell proliferation and metastasis - Google Patents

Description

A capsule structure of Antrodia camphorata inhibiting the growth and spread of lymphoma tumor cells

This creation relates to the technical field of a capsule structure that can embed powder.

Antrodia camphorata, also known as Antrodia camphorata or Burdock mushroom, belongs to the fungi community (Fungi), Basidiomycota, Basidiomycotina, Homobasidiomycetes, and taxonomy. Aphyllophorales, Polyporaceae, Antrodia. Antrodia camphorata grows in the deep mountains of 450~2000 meters above sea level, also known as burdock mushroom, red peony, oyster mushroom, and oyster mushroom. It grows only on the inner wall of the decaying heartwood of Taiwan's unique burdock trunk. Anthraquinone is known to have a variety of active ingredients, which makes the Antrodia camphorata have the functions of protecting the liver, enhancing immunity, resisting oxidation and inhibiting the growth of tumor cells. It is a famous and precious medicinal fungus in Taiwan and has the reputation of "the ruby in the forest".

The body of Ox sylvestris is perennial, sessile and cork-to-wood. It has a strong aroma of eucalyptus and has a variety of shapes. It has a plate shape, a bell shape, a horseshoe shape or a tower shape. It is close to the surface of the wood and has a pore shape on the surface of the mushroom. It is bright red at the beginning of life, and becomes milky white, reddish brown, light brown or yellowish brown as the growth progresses. The periphery is often radial and spreads to the periphery, showing a semicircular or irregular shape.

Phytochemical studies have shown that the body complex of Antrodia camphorata contains polysaccharides (30-50%), triterpenoids (30%), steroids, superoxide dismutase and amino acids. In Taiwan's folk medicine therapy, the body of A. sylvestris is considered to have certain medical effects. The fruiting body is finely ground into a dry powder or taken orally in a boiled way. It is a food-borne mushroom with a therapeutic effect. It has detoxification and anti-inflammatory. , anti-tumor, inhibition of vascular proliferation and treatment of liver disease and other activities.

Malignant lymphoma, commonly known as lymphoma, includes two diseases, non-Hodgkin's lymphoma and Hodgkin's disease. The difference between the two is the difference in pathological morphology and the difference in clinical manifestations. Westerner Hodgkin's disease is more common, the prognosis is better, while the Orientals are more than Hodgkin's lymphoma. At present, it seems that the world's malignant lymphoma has a trend of increasing year by year, and the rickets rate is increasing year by year.

There are many hypotheses about the causes of malignant lymphoma. Most scholars believe that in addition to physical, chemical, and viral infections (EBV), the patient's own immune function defects play an important role, such as kidney transplanters, AIDS HIV. Or a special virus infected person, the rate of rickets is dozens of times that of normal people. Family and genetic tendencies are rare.

Possible causes of lymphoma include loss of the immune system, viral infection, use of radiation or drugs, and heredity. Studies have shown that the incidence of lymphoma in all age groups is very average, and the proportion of men and women is about equal. Lymphoma is most often characterized by lymphadenopathy as an early symptom, especially in the lymph nodes of the neck, armpits or groin. Sections, and often painless clusters of lymph nodes, some patients may have systemic symptoms such as fever, night sweats, weight loss, long-term burnout or weakness, skin itching and rash, etc. The first stage of the lymphoma is not in the lymph glands, but in the internal organs, such as the stomach, the large intestine, the mediastinum of the lungs, etc., and its symptoms include stomach pain, stomach bleeding, intestinal obstruction, or lung dyspnea. .

Patients with lymphoma who do not receive treatment generally live on average for no more than one to two years. However, those who receive appropriate radiation therapy or chemotherapy will have a 60% to 70% chance of achieving complete remission, and 40% of these patients may relapse. Those who relapsed after two years of treatment have a better prognosis and they still have a good response to the second chemotherapy. Regardless of whether there has been recurrence, as long as the appropriate treatment, the survival rate of more than seven years accounts for about 40% of all lymphoma, and this result is quite good in cancer.

It is known from many experiments that the body of A. angustifolia has anti-cancer effect, and its components are also analyzed. Therefore, providing a better treatment or prevention of lymphoma in these patients is an urgent problem to be solved.

Therefore, in view of the above-mentioned lack of the above-mentioned derivatives, the creators of this case have improved and innovated, in addition to the development of a burdock powder, the active ingredient of which has the effect of inhibiting the growth and spread of lymphoma tumor cells; in addition, with the capsule structure of the creation, It is easy for the user to ingest enough of the Antrodia camphorata powder to treat or prevent lymphoma. Therefore, this article "a structure of a capsule of Astragalus membranaceus that inhibits the growth and spread of lymphoma cells".

The purpose of the present invention is to provide a structure of an Antrodia camphorata powder capsule for inhibiting the growth of lymphoma tumor cells.

A second object of the present invention is to provide a capsule structure in which the active ingredient of the Antrodia camphorata powder is exerted in a user's body to inhibit the growth and spread of lymphoma tumor cells.

One of the above-mentioned creative purposes can inhibit the growth and expansion of lymphoma tumor cells The powdered capsule structure of A. sinensis comprises: a capsule shell, a protective layer, and a core; the core layer is covered by the protective layer, and the protective layer is coated with a capsule.

The structure of the Antrodia camphorata powder capsule provided by the present invention can be preserved for a long time in addition to the contained Antrodia camphorata powder (and its active ingredient); in addition, the core of the Antrodia camphorata powder (and its active ingredient) can also inhibit lymphatics. Cancer cells grow and spread. The capsule structure provided by this creation can be easily taken by the user, so that it can be used in combination with other treatments in addition to daily health care.

1‧‧‧Capsule structure

11‧‧‧ capsule

12‧‧‧Protective layer

13‧‧‧ core

Figure 1 is a cross-sectional view showing the structure of an Antrodia camphorata powder capsule which inhibits the growth and spread of lymphoma tumor cells.

The present invention provides a structure of an Antrodia camphorata powder capsule which inhibits the growth and spread of lymphoma tumor cells, and is described in detail according to the present creation, and is referred to the first figure.

The present invention comprises a structure 1 for inhibiting the growth and spread of lymphoma tumor cells, which comprises, in order from the outside to the inside, a capsule 11, a protective layer 12, and a core 13; the core 13 is protected by the protective layer 12 The coating, in addition to blocking the oxidation between the external environment and the core 13, can also be used to protect the active constituents of the Antrodia camphorata in the core 13 from being damaged by factors such as gastric acid. In addition, the protective layer 12 is further covered by a capsule 11 to protect the core 13 and the protective layer 12 from physical factors such as heavy pressure, spikes, and the like.

The components used in the capsule 11 include, but are not limited to, gelatin (gelatin) (Gelatin)), Methyl cellulose, Hydroxymethyl propyl cellulose, Hydroxymethyl propyl cellulose, Polyvinyl alcohol, Polyvinylpyrrolidone (Polyvinyl pyrrolidone), Cellulose acetate phthalate, Hydroxypropyl methyl phthalate or other materials suitable for the present invention; wherein the gelatin may comprise animal gelatin ( Made from animal sources such as fish skin and pig skin) and vegetable gelatin (eg hydroxypropyl methylcellulose (HPMC)).

The protective layer 12 may include, but is not limited to, an excipient, a disintegrant, an enteric coating, a binder, a diluent, a coating agent, a swelling agent, a lubricant, a flavoring agent, a sweetener, a solubilizing agent. Or any combination thereof.

Wherein, the excipient may be a sugar, including lactose, sucrose, mannitol, sorbitol; the cellulose preparation is, for example, corn starch, wheat starch, rice starch, potato starch, gelatin, tragacanth, etc. or other Materials suitable for this creation; they can be used to increase the mouthfeel, support the overall structure, and protect the core 13.

The core 13 contains an Antrodia camphorata powder (active substance) which can be used to inhibit the growth and spread of lymphoma tumor cells. The Antrodia camphorata powder can be made from the fruit body of Antrodia camphorata.

The above-mentioned capsule structure 1 may also be suitably added with one or more kinds of preservatives, colorants, flavors and flavors or other additives suitable for the present invention which are commonly used in the field, so as to shape, preserve and color. Add flavor.

The above powder capsule structure can be prepared by taking it in a capsule for oral administration, or by taking it directly or by other forms suitable for the present invention.

The detailed description above is specific to one of the possible implementations of this creation. It is to be understood that the examples are not intended to limit the scope of the patents of the present invention, and that equivalents or modifications may be included in the scope of the patent.

In summary, the technical features disclosed in this case have fully met the statutory patent requirements for novelty, advancement and industrial applicability. If you apply in accordance with the law, you are requested to approve the new patent application for your invention. Will.

1‧‧‧Capsule structure

11‧‧‧ capsule

12‧‧‧Protective layer

13‧‧‧ core

Claims (5)

An anathopin powder capsule structure for inhibiting the growth and spread of lymphoma tumor cells, comprising: a capsule shell, a protective layer, and a core from the outside to the inside; the core layer is covered by the protective layer, and the protective layer is further Covered with a capsule. The capsule structure according to claim 1, wherein the composition of the capsule comprises gelatin, methylcellulose, hydroxypropylmethylcellulose, hydroxypropylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, Cellulose acetate phthalate, hydroxypropyl cellulose phthalate. The capsule structure according to claim 1, wherein the component of the protective layer comprises an excipient, a disintegrant, an enteric coating, a binder, a diluent, a coating agent, a swelling agent, a lubricant, Flavoring agents, sweeteners, solubilizers. The capsule structure of claim 3, wherein the component of the excipient comprises lactose, sucrose, mannitol, sorbitol, corn starch, wheat starch, rice starch, potato starch, gelatin, tragacanth. The capsule structure of claim 1, wherein the core comprises anthraquinone powder prepared from a body of A. nigra.