TWI910148B - 芳基或雜芳基衍生物 - Google Patents

芳基或雜芳基衍生物

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Publication number
TWI910148B
TWI910148B TW110113543A TW110113543A TWI910148B TW I910148 B TWI910148 B TW I910148B TW 110113543 A TW110113543 A TW 110113543A TW 110113543 A TW110113543 A TW 110113543A TW I910148 B TWI910148 B TW I910148B
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TW
Taiwan
Prior art keywords
oxybenzonitrile
methyl
pyrimidin
aminoethyl
pyridin
Prior art date
Application number
TW110113543A
Other languages
English (en)
Chinese (zh)
Other versions
TW202204321A (zh
Inventor
杉山栄
横坂卓也
南園邦夫
河名旭
金子俊幸
丸山明伸
佐佐木浩介
細田信之介
小清水正樹
竹內進
加藤賢太
納格斯瑞 恰卡
布雷特 強森
雷恩 懷特
趙偉
Original Assignee
日商帝人製藥股份有限公司
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Application filed by 日商帝人製藥股份有限公司 filed Critical 日商帝人製藥股份有限公司
Publication of TW202204321A publication Critical patent/TW202204321A/zh
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Publication of TWI910148B publication Critical patent/TWI910148B/zh

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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