CN107253952B - 具有抗胃癌活性的trpc6抑制剂及其制备方法和用途 - Google Patents
具有抗胃癌活性的trpc6抑制剂及其制备方法和用途 Download PDFInfo
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- CN107253952B CN107253952B CN201710649517.7A CN201710649517A CN107253952B CN 107253952 B CN107253952 B CN 107253952B CN 201710649517 A CN201710649517 A CN 201710649517A CN 107253952 B CN107253952 B CN 107253952B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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CN201710649517.7A CN107253952B (zh) | 2017-08-01 | 2017-08-01 | 具有抗胃癌活性的trpc6抑制剂及其制备方法和用途 |
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CN107253952A CN107253952A (zh) | 2017-10-17 |
CN107253952B true CN107253952B (zh) | 2019-07-30 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US11485740B2 (en) * | 2018-02-15 | 2022-11-01 | Boehringer Ingelheim International Gmbh | Inhibitors of TRPC6 |
EP3959206A1 (en) * | 2019-04-12 | 2022-03-02 | Boehringer Ingelheim International GmbH | Inhibitors of trpc6 |
CN110205384B (zh) * | 2019-05-21 | 2023-05-02 | 深圳市龙岗区耳鼻咽喉医院 | Spz1的用途及其抑制剂的用途和药物筛选方法 |
AR121846A1 (es) | 2020-04-16 | 2022-07-13 | Teijin Pharma Ltd | Derivado de arilo o heteroarilo |
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CN103694242B (zh) * | 2013-12-10 | 2016-01-06 | 昆明翔昊科技有限公司 | 吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用 |
WO2016011019A1 (en) * | 2014-07-15 | 2016-01-21 | The Brigham And Women's Hospital, Inc. | Compositions and methods for inhibiting bmp |
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Application publication date: 20171017 Assignee: Shandong Luye Pharmaceutical Co.,Ltd. Assignor: Yantai University Contract record no.: X2020990000070 Denomination of invention: TRPC6 inhibitor with anti-gastric cancer activity, and preparation method and application thereof Granted publication date: 20190730 License type: Common License Record date: 20200210 |
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Denomination of invention: TRPC6 inhibitor with anti gastric cancer activity and its preparation method and Application Effective date of registration: 20211214 Granted publication date: 20190730 Pledgee: Yantai financing guarantee Group Co.,Ltd. Pledgor: Yantai University Registration number: Y2021980014850 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220317 Granted publication date: 20190730 Pledgee: Yantai financing guarantee Group Co.,Ltd. Pledgor: Yantai University Registration number: Y2021980014850 |
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