TWI897846B - 可誘導之嵌合細胞激素受體 - Google Patents

可誘導之嵌合細胞激素受體

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Publication number
TWI897846B
TWI897846B TW108107136A TW108107136A TWI897846B TW I897846 B TWI897846 B TW I897846B TW 108107136 A TW108107136 A TW 108107136A TW 108107136 A TW108107136 A TW 108107136A TW I897846 B TWI897846 B TW I897846B
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Taiwan
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domain
cells
cell
receptor
immune cell
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TW108107136A
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English (en)
Chinese (zh)
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TW201945402A (zh
Inventor
安德魯 羅斯 納格
史賓瑟 帕克
瑞格斯 嘉維爾 費南多 恰佩羅
君慧 林
布拉康 湯瑪士 約翰 凡
Original Assignee
美商異基因治療有限公司
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Publication of TW201945402A publication Critical patent/TW201945402A/zh
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12Y502/00—Cis-trans-isomerases (5.2)
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    • C12Y502/01008—Peptidylprolyl isomerase (5.2.1.8), i.e. cyclophilin
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
TW108107136A 2018-03-02 2019-03-04 可誘導之嵌合細胞激素受體 TWI897846B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862637600P 2018-03-02 2018-03-02
US62/637,600 2018-03-02
WOPCT/US2019/020340 2019-03-01
PCT/US2019/020340 WO2019169290A1 (en) 2018-03-02 2019-03-01 Inducible chimeric cytokine receptors

Publications (2)

Publication Number Publication Date
TW201945402A TW201945402A (zh) 2019-12-01
TWI897846B true TWI897846B (zh) 2025-09-21

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TW108107136A TWI897846B (zh) 2018-03-02 2019-03-04 可誘導之嵌合細胞激素受體

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US (2) US12163169B2 (enExample)
EP (1) EP3759132A1 (enExample)
JP (2) JP7526101B2 (enExample)
KR (2) KR20250123938A (enExample)
CN (1) CN111819192A (enExample)
AR (1) AR114273A1 (enExample)
AU (2) AU2019227979B2 (enExample)
BR (1) BR112020017734A2 (enExample)
CA (1) CA3091681A1 (enExample)
IL (2) IL276831B2 (enExample)
MX (2) MX2020009051A (enExample)
SG (1) SG11202007771VA (enExample)
TW (1) TWI897846B (enExample)
WO (1) WO2019169290A1 (enExample)

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WO2019169290A1 (en) 2018-03-02 2019-09-06 Allogene Therapeutics, Inc. Inducible chimeric cytokine receptors
KR20200138741A (ko) 2018-04-02 2020-12-10 내셔널 유니버시티 오브 싱가포르 면역 세포에서 발현되는 막-결합 항-사이토카인 비-신호전달 결합제를 이용한 인간 사이토카인의 중화
JP7560882B2 (ja) 2018-08-29 2024-10-03 ナショナル ユニヴァーシティー オブ シンガポール 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法
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KR102829018B1 (ko) 2021-03-03 2025-07-04 서울대학교산학협력단 키메릭 항원 수용체-대식 세포의 제조 방법 및 그 세포의 용도
JP2024515577A (ja) * 2021-04-07 2024-04-10 プロヴィンシャル ヘルス サービシーズ オーソリティ 修飾された顆粒球コロニー刺激因子（ｇ－ｃｓｆ）及びこれに結合するキメラサイトカイン受容体
CN113512125B (zh) * 2021-04-26 2024-01-19 北京双赢科创生物科技有限公司 一种携带stat结合基序的嵌合抗原受体分子及表达该嵌合抗原受体分子的nk细胞
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