TWI823890B - 包含苯基磺醯胺之醫藥組合物及其治療應用 - Google Patents

包含苯基磺醯胺之醫藥組合物及其治療應用 Download PDF

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Publication number
TWI823890B
TWI823890B TW108100722A TW108100722A TWI823890B TW I823890 B TWI823890 B TW I823890B TW 108100722 A TW108100722 A TW 108100722A TW 108100722 A TW108100722 A TW 108100722A TW I823890 B TWI823890 B TW I823890B
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certain embodiments
mixtures
tautomers
compound
pharmaceutically acceptable
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TW108100722A
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Chinese (zh)
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TW201929846A (zh
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納茲尼 敦吉
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美商克拉治療有限責任公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW108100722A 2018-01-10 2019-01-08 包含苯基磺醯胺之醫藥組合物及其治療應用 TWI823890B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862615869P 2018-01-10 2018-01-10
US62/615,869 2018-01-10

Publications (2)

Publication Number Publication Date
TW201929846A TW201929846A (zh) 2019-08-01
TWI823890B true TWI823890B (zh) 2023-12-01

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Family Applications (2)

Application Number Title Priority Date Filing Date
TW108100722A TWI823890B (zh) 2018-01-10 2019-01-08 包含苯基磺醯胺之醫藥組合物及其治療應用
TW112141994A TW202406538A (zh) 2018-01-10 2019-01-08 包含苯基磺醯胺之醫藥組合物及其治療應用

Family Applications After (1)

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TW112141994A TW202406538A (zh) 2018-01-10 2019-01-08 包含苯基磺醯胺之醫藥組合物及其治療應用

Country Status (7)

Country Link
US (3) US11701334B2 (https=)
EP (1) EP3737382A1 (https=)
JP (3) JP7395480B2 (https=)
AU (2) AU2019207491A1 (https=)
CA (1) CA3087856A1 (https=)
TW (2) TWI823890B (https=)
WO (1) WO2019139869A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7395480B2 (ja) 2018-01-10 2023-12-11 クラ セラピューティクス, エルエルシー フェニルスルホンアミドを含む薬学的組成物、及びそれらの治療的適用
EP3997068A1 (en) * 2019-07-11 2022-05-18 Cura Therapeutics, LLC Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications for the treatment of neurodegenerative diseases
CA3146159A1 (en) * 2019-07-11 2021-01-14 Cura Therapeutics, Llc Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2008129288A2 (en) * 2007-04-19 2008-10-30 Boehringer Ingelheim International Gmbh Disulfonamides useful in the treatment of inflammation

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Patent Citations (1)

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Also Published As

Publication number Publication date
US20210052525A1 (en) 2021-02-25
JP2023182589A (ja) 2023-12-26
US11701334B2 (en) 2023-07-18
JP7395480B2 (ja) 2023-12-11
CA3087856A1 (en) 2019-07-18
TW201929846A (zh) 2019-08-01
JP2021510168A (ja) 2021-04-15
US20240016768A1 (en) 2024-01-18
JP2026021312A (ja) 2026-02-10
EP3737382A1 (en) 2020-11-18
AU2024259810A1 (en) 2024-11-28
WO2019139869A1 (en) 2019-07-18
AU2019207491A1 (en) 2020-07-30
US20250177334A1 (en) 2025-06-05
TW202406538A (zh) 2024-02-16

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