TWI775051B - 骨釘 - Google Patents
骨釘 Download PDFInfo
- Publication number
- TWI775051B TWI775051B TW109105845A TW109105845A TWI775051B TW I775051 B TWI775051 B TW I775051B TW 109105845 A TW109105845 A TW 109105845A TW 109105845 A TW109105845 A TW 109105845A TW I775051 B TWI775051 B TW I775051B
- Authority
- TW
- Taiwan
- Prior art keywords
- antibacterial
- bone
- hollow portion
- layer
- hollow
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title claims description 70
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 146
- 239000007943 implant Substances 0.000 claims abstract description 50
- 230000000149 penetrating effect Effects 0.000 claims abstract description 4
- 229910052709 silver Inorganic materials 0.000 claims description 34
- 239000004332 silver Substances 0.000 claims description 34
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical group [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 33
- 241000894006 Bacteria Species 0.000 claims description 4
- 230000000845 anti-microbial effect Effects 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 description 16
- 208000015181 infectious disease Diseases 0.000 description 15
- 239000011248 coating agent Substances 0.000 description 7
- 238000000576 coating method Methods 0.000 description 7
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 230000002093 peripheral effect Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 239000004696 Poly ether ether ketone Substances 0.000 description 2
- 239000000560 biocompatible material Substances 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 238000005229 chemical vapour deposition Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000005121 nitriding Methods 0.000 description 2
- 238000005240 physical vapour deposition Methods 0.000 description 2
- 229920002530 polyetherether ketone Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 238000007740 vapor deposition Methods 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
- 229910052581 Si3N4 Inorganic materials 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 238000007743 anodising Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000002639 bone cement Substances 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 238000005255 carburizing Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 229910001431 copper ion Inorganic materials 0.000 description 1
- 238000007772 electroless plating Methods 0.000 description 1
- 238000009713 electroplating Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
- -1 silver ions Chemical class 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000007751 thermal spraying Methods 0.000 description 1
- 238000007669 thermal treatment Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000007738 vacuum evaporation Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/864—Pins or screws or threaded wires; nuts therefor hollow, e.g. with socket or cannulated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/866—Material or manufacture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00889—Material properties antimicrobial, disinfectant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B2017/561—Implants with special means for releasing a drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Percussion Or Vibration Massage (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| WOPCT/JP2020/006385 | 2020-02-19 | ||
| PCT/JP2020/006385 WO2021166091A1 (ja) | 2020-02-19 | 2020-02-19 | インプラント |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW202131873A TW202131873A (zh) | 2021-09-01 |
| TWI775051B true TWI775051B (zh) | 2022-08-21 |
Family
ID=77390668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW109105845A TWI775051B (zh) | 2020-02-19 | 2020-02-24 | 骨釘 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220378986A1 (https=) |
| EP (1) | EP4108195A4 (https=) |
| JP (1) | JP7411062B2 (https=) |
| KR (1) | KR102736139B1 (https=) |
| CN (1) | CN115135261B (https=) |
| TW (1) | TWI775051B (https=) |
| WO (1) | WO2021166091A1 (https=) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012064402A1 (en) * | 2010-11-12 | 2012-05-18 | Silver Bullet Therapeutics, Inc. | Bone implant and systems that controllably releases silver |
| WO2013157756A1 (ko) * | 2012-04-19 | 2013-10-24 | Hwang Jeong Bin | 치아 임플란트 |
| WO2016077676A1 (en) * | 2014-11-14 | 2016-05-19 | Silver Bullet Therapeutics, Inc. | Enhancement of antimicrobial silver, silver coatings, or silver platings |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5933834Y2 (ja) | 1978-12-20 | 1984-09-20 | 澁谷工業株式会社 | 複列充填機のバルブ開閉装置 |
| JPH05137739A (ja) * | 1991-11-22 | 1993-06-01 | Terumo Corp | 人工関節 |
| CA2360904C (en) * | 1999-02-04 | 2007-05-22 | Michael Ahrens | Bone screw |
| US6565913B2 (en) * | 2001-07-24 | 2003-05-20 | Southwest Research Institute | Non-irritating antimicrobial coatings and process for preparing same |
| CA2583911A1 (en) * | 2004-10-28 | 2006-05-11 | Microchips, Inc. | Orthopedic and dental implant devices providing controlled drug delivery |
| US20080051911A1 (en) * | 2006-08-23 | 2008-02-28 | Wilson-Cook Medical Inc. | Stent with antimicrobial drainage lumen surface |
| ATE458508T1 (de) * | 2006-08-28 | 2010-03-15 | Wilson Cook Medical Inc | Stent mit antimikrobieller drainagelumen- oberfläche |
| FR2941859B1 (fr) * | 2009-02-09 | 2012-04-06 | Memometal Technologies | Vis d'osteosynthese. |
| US9089377B2 (en) * | 2009-02-23 | 2015-07-28 | Orthopediatrics Corp. | Bone screw |
| JP5590596B2 (ja) | 2009-05-20 | 2014-09-17 | 学校法人明治大学 | 抗菌性医療機器とその製造方法 |
| US10265435B2 (en) * | 2009-08-27 | 2019-04-23 | Silver Bullet Therapeutics, Inc. | Bone implant and systems and coatings for the controllable release of antimicrobial metal ions |
| EP2475316B8 (en) * | 2009-09-10 | 2016-07-13 | Woodwelding AG | Device to be implanted in a human or animal body for signal delivery or acquisition within the body |
| EP2827789A4 (en) * | 2012-03-09 | 2016-01-13 | Si Bone Inc | IMPLANT WITH THREAD |
| TWM485703U (zh) * | 2013-11-25 | 2014-09-11 | Taipei Biotechnology Ltd Inc | 人工牙根植體 |
| JP2015167779A (ja) | 2014-03-10 | 2015-09-28 | 株式会社スワ | 骨折治療用プレート |
| RU147760U1 (ru) * | 2014-06-20 | 2014-11-20 | Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы | Фенестрированный канюлированный компрессирующий винт для остеосинтеза переломов костей конечностей |
| CN104939880B (zh) * | 2015-07-17 | 2019-08-06 | 爱微捷成都医疗科技有限公司 | 一种记忆合金缝合钉及缝合器 |
| WO2017150532A1 (ja) * | 2016-02-29 | 2017-09-08 | メドトロニックソファモアダネック株式会社 | 抗菌性生体内埋込用器具 |
| KR20180134396A (ko) * | 2016-05-31 | 2018-12-18 | 올림푸스 테루모 바이오머티리얼 가부시키가이샤 | 뼈 플레이트 및 뼈 플레이트 시스템 |
-
2020
- 2020-02-19 JP JP2022501456A patent/JP7411062B2/ja active Active
- 2020-02-19 CN CN202080096723.XA patent/CN115135261B/zh active Active
- 2020-02-19 KR KR1020227027299A patent/KR102736139B1/ko active Active
- 2020-02-19 EP EP20920335.5A patent/EP4108195A4/en active Pending
- 2020-02-19 WO PCT/JP2020/006385 patent/WO2021166091A1/ja not_active Ceased
- 2020-02-24 TW TW109105845A patent/TWI775051B/zh active
-
2022
- 2022-08-04 US US17/880,836 patent/US20220378986A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012064402A1 (en) * | 2010-11-12 | 2012-05-18 | Silver Bullet Therapeutics, Inc. | Bone implant and systems that controllably releases silver |
| WO2013157756A1 (ko) * | 2012-04-19 | 2013-10-24 | Hwang Jeong Bin | 치아 임플란트 |
| WO2016077676A1 (en) * | 2014-11-14 | 2016-05-19 | Silver Bullet Therapeutics, Inc. | Enhancement of antimicrobial silver, silver coatings, or silver platings |
Also Published As
| Publication number | Publication date |
|---|---|
| US20220378986A1 (en) | 2022-12-01 |
| JPWO2021166091A1 (https=) | 2021-08-26 |
| WO2021166091A1 (ja) | 2021-08-26 |
| KR102736139B1 (ko) | 2024-12-02 |
| CN115135261A (zh) | 2022-09-30 |
| EP4108195A1 (en) | 2022-12-28 |
| CN115135261B (zh) | 2025-06-20 |
| KR20220124771A (ko) | 2022-09-14 |
| EP4108195A4 (en) | 2023-11-22 |
| JP7411062B2 (ja) | 2024-01-10 |
| TW202131873A (zh) | 2021-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GD4A | Issue of patent certificate for granted invention patent |