TWI769177B - 經修飾之寡核苷酸及使用方法 - Google Patents

經修飾之寡核苷酸及使用方法 Download PDF

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TWI769177B
TWI769177B TW106131624A TW106131624A TWI769177B TW I769177 B TWI769177 B TW I769177B TW 106131624 A TW106131624 A TW 106131624A TW 106131624 A TW106131624 A TW 106131624A TW I769177 B TWI769177 B TW I769177B
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oligonucleotide
formula
nucleotides
modified
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TW106131624A
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TW201825103A (zh
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謝爾蓋 格里亞茲諾夫
里歐尼德 貝奇曼
勁 洪
維韋克 芮潔瓦恩蘇
安提薩 斯托伊切瓦
孟提諾 馬丁內茲
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美商艾洛斯生物製藥公司
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    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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TW106131624A 2016-09-14 2017-09-14 經修飾之寡核苷酸及使用方法 TWI769177B (zh)

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US201662394738P 2016-09-14 2016-09-14
US201662394739P 2016-09-14 2016-09-14
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US20230250125A1 (en) * 2020-04-01 2023-08-10 Janssen Biopharma, Inc. Nucleic acid polymers
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CN114057816B (zh) * 2020-07-30 2025-02-11 浙江柏拉阿图医药科技有限公司 富含腺嘌呤硫代磷酸酯化寡核苷酸及其抗肝炎病毒的应用
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CN119095963A (zh) 2022-01-10 2024-12-06 杭州浩博医药有限公司 乙型肝炎病毒(hbv)表达的调节
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MX2019002960A (es) 2019-09-18
BR112019004911A2 (pt) 2019-06-25
KR102627418B1 (ko) 2024-01-19
KR20190047025A (ko) 2019-05-07
US20180135054A1 (en) 2018-05-17
KR20230033736A (ko) 2023-03-08
MA46422A (fr) 2019-07-24
KR102533038B1 (ko) 2023-05-17
KR20240010761A (ko) 2024-01-24
US10793859B2 (en) 2020-10-06
JP7478210B2 (ja) 2024-05-02
WO2018053185A1 (en) 2018-03-22
EP3512949A1 (en) 2019-07-24
JP6970187B2 (ja) 2021-11-24
CN109952378A (zh) 2019-06-28
JP7170820B2 (ja) 2022-11-14
MX2023014145A (es) 2023-12-13
AU2017326372B2 (en) 2023-12-07
IL265359B2 (en) 2025-02-01
TW201825103A (zh) 2018-07-16
US20210040483A1 (en) 2021-02-11
US12077757B2 (en) 2024-09-03
JP2019529406A (ja) 2019-10-17
JP2022023936A (ja) 2022-02-08
CA3037042A1 (en) 2018-03-22
US20250092400A1 (en) 2025-03-20
AU2024201485A1 (en) 2024-03-28
CN109952378B (zh) 2024-09-17
JP2023011793A (ja) 2023-01-24
RU2019111020A3 (enExample) 2021-06-22
IL265359B1 (en) 2024-10-01
IL315071A (en) 2024-10-01
RU2019111020A (ru) 2020-10-15
IL265359A (en) 2019-05-30

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