TWI716751B - Hair growth stimulating dressing - Google Patents

Abstract

The present invention discloses a hair growth stimulating dressing having advantages of simple manufacturing processes, low manufacture cost and reasonable selling price. To fabricate the hair growth stimulating dressing, it is firstly took mesoporous silica nanoparticles doped with lanthanide elements and at least one polymer matrix as raw materials to fabricate a plurality of biological fibers; and subsequently, the biological fibers are weaved to a biological textile. Particularly, the hair growth stimulating dressing can indeed show a promotion effect of hair growth on the heads of BALB/c nude mice after being covered onto the head of the nude mice. Therefore, compared to the fact that the commercial hair growth promoting products only just can show apparent hair growing effect on user’s head after being continuously used for at least 4 months, this hair growth stimulating dressing only takes 7 days to exhibit positive hair growing effect on user’s head.

Description

Dressings that promote hair growth

The present invention relates to the technical field of biotechnology, in particular to a dressing that promotes hair growth.

Hair loss is the result of combining genetic factors, environmental factors and physiological conditions. With the increase of environmental pollutants and the accumulation of life pressure, hair loss has become an inevitable problem for most middle-aged men.

Currently, there are a variety of hair growth products on the market, such as Luo Jian and Propecia. Although it has a good clinical effect, nearly half of the users can only grow short hair after using it. On the other hand, although Propecia also has the effect of increasing hair volume, its effect on hair increase will decrease significantly after one year of use. Before using a hair growth product, you must carefully consider the side effects that the hair growth product will bring. For example, failure to build will cause side effects such as scalp itching, blurred vision, chest pain, low blood pressure, and decreased libido. Propex can cause male users The side effects of decreased libido, erectile dysfunction and ejaculation dysfunction.

On the other hand, the key point that must be considered at the same time is that the prices of commercially available hair growth products are too expensive, resulting in low-income users who would rather bear the baldness crisis than spend too much money to buy hair growth products. It can be seen that the most important issue for manufacturers of hair growth products is how to provide a hair growth product with a simple process, low cost, and easy to use; and the sales price of the hair growth product must be within the reach of ordinary users. Accepted. Therefore, the inventor of this case tried his best to research and invent, and finally developed a dressing for promoting hair growth of the present invention.

The main purpose of the present invention is to provide a dressing that promotes hair growth. Unlike commercially available hair growth compositions, which have complex formulations and expensive prices, the inventors of the present invention specially used electrospinning or spinning technology to combine a plurality of lanthanide-doped silica nanoparticles with a polymer The material is processed into a plurality of biological yarns, and then the plurality of biological yarns are woven into a biological fabric with a weaving equipment, which is used as a dressing for promoting hair growth of the present invention. It is conceivable that compared with commercially available hair growth compositions, the hair growth-promoting dressing of the present invention has the absolute advantage of low manufacturing cost. In addition, the experimental results also confirmed that after seven days of continuous use of the hair growth-promoting dressing of the present invention, the head of nude mice has a significant hair growth effect. Obviously, compared with the commercially available hair growth composition that must be used for at least four months for a long time to show the effect of hair growth, the hair growth-promoting dressing system of the present invention exhibits an immediate hair growth effect.

In order to achieve the above-mentioned main purpose of the present invention, the inventor of the present case provides an embodiment of the hair growth-promoting dressing, which is formed by interlacing a plurality of warp yarns and a plurality of weft yarns; wherein, the warp yarn and the weft yarn are both A biological yarn, and the biological yarn system includes: a polymer sheath; and a plurality of silica nanoparticles doped with lanthanide series metal with holes in it, doped or coated in the polymer sheath Wherein, the diameter of the porous silica nanoparticle in the doped lanthanide series metal is less than 100nm, and every 1 cm2 of the hair growth promoting dressing contains at least 16.48 mg of the plural A pore-doped silicon dioxide nanoparticle in a lanthanide series metal.

In addition, in order to achieve the above-mentioned main purpose of the present invention, the inventor of the present application provides another embodiment of the hair growth-promoting dressing, which is formed by interlacing a plurality of warp yarns and a plurality of weft yarns; wherein, the plurality of warp yarns And the plurality of warp yarns include a plurality of first yarns and a plurality of second yarns; wherein, the first yarn is a biological yarn, and the second yarn is a natural yarn or an artificial yarn Thread; the biological yarn system includes: a polymer sheath; and a plurality of doped lanthanide metal in the hole silicon dioxide nanoparticles, doped or coated in the polymer sheath; wherein, The diameter of the porous silicon dioxide nanoparticle in the doped lanthanide metal is less than 100 nm, and every 1 cm2 of the hair growth promoting dressing contains at least 16.48 mg of the plurality of doped lanthanide particles Silica nano particles with holes in the metal.

In order to more clearly describe the hair growth-promoting dressing proposed by the present invention, the preferred embodiments of the present invention will be described in detail below in conjunction with the drawings.

First embodiment

Please refer to Fig. 1, which shows a schematic perspective view of a first embodiment of a dressing for promoting hair growth according to the present invention. In the first embodiment, the hair growth-promoting dressing 1 of the present invention is a bio-fabric, which is formed by interlacing a plurality of warp yarns 1WA and a plurality of weft yarns 1WE. Please also refer to Figure 2, which shows a cross-sectional view of the biological yarn. According to the design of the present invention, the warp yarn 1WA and the weft yarn 1WE are both a biological yarn 11, and the biological yarn 11 includes: a polymer sheath 111 and a plurality of doped lanthanide metals Mesoporous silica nanoparticles (MSN) 112 are included. In particular, the porous silica nanoparticle 112 in the doped lanthanide series metal is represented by the chemical formula SiO ₂ ^x :Eu ^y Gd ^z , and it is doped or coated in the polymer sheath 111. It must be specifically noted that x, y, and z in the chemical formula are weight percentage values; and, x is between 99 wt% and 99.8 wt%, and y and z are between 0.1 wt% and 0.5 wt%.

The present invention does not particularly limit the type or material of the polymer sheath 111, so the polymer sheath 111 can be any one of the following: gelatin/trifluoroethanol composite sheath, gelatin/trifluoroethanol/polycaprolactone composite sheath, gelatin /Trifluoroethanol/Polylactic acid sheath, Polyester (PET) sheath, Polyurethane (PU) sheath, Poly(vinyl chloride) (PVC) sheath, Polypropylene (PP) sheath, Polyamide (PA) sheath, a combination of the above two, or a combination of two or more of the above. It is worth noting that gelatin, polycaprolactone (PCL), and polylactic acid (PLA) are biodegradable high-molecular polymers, and the others are common synthetic high-molecular materials.

First manufacturing method

To obtain the hair growth-promoting dressing 1 of the present invention, the porous silicon dioxide nanoparticle (MSN) 112 in the doped lanthanide metal must be prepared first, including the following process steps: (1) Using cetyl bromide Trimethylammonium (hexadecyl trimethyl ammonium bromide, cetyltrimethylammonium bromide, CTAB) is used as a surfactant and sodium hydroxide (NaOH) is used as the alkali metal compound, and the two are added to the distilled deionized water, followed by heating and stirring (2) Add ethyl orthosilicate (Tetraethyl orthosilicate, TEOS), europium chloride, and gyrium chloride to the solution of the previous step (1), and stir it at a constant temperature; (3) add the previous step ( 2) Centrifuging, washing, and filtering the obtained solution; (4) drying the filtered precipitate obtained in the previous step (3); and (5) calcining the dried precipitate obtained in the previous step (4).

According to the aforementioned steps (1)-(5), the porous silicon dioxide nanoparticle 112 with the chemical formula SiO ₂ ^x :Eu ^y Gd ^z doped in the lanthanide series metal can be obtained. Continuing, the biological yarn 11 can be manufactured through electro-spinning equipment. Please refer to FIGS. 3A to 3B, which are schematic diagrams showing the manufacturing process of biological yarn. As shown in the schematic diagram (a) of Figure 3A, first the gelatin raw material 11a and the solvent 11b are stirred and mixed in the reaction flask 2; wherein the solvent 11b is 2,2,2-trifluoroethanol (2,2,2 -Trifluoroethanol, TFE). Next, as shown in the schematic diagram (b) of FIG. 3A, the porous silica nanoparticles 112 in the doped lanthanide metal and the secondary water are added to the reaction flask 2 and mixed with stirring. Continuing, as shown in FIG. 3B, the solution in the reaction flask 2 is poured into a spinning device 3, wherein a collecting device 4 is arranged below the spinning device 3, and the collecting device 4 and the spinning device 3 At the same time, it is electrically connected to a voltage generating device 5. As is well known by engineers familiar with electrospinning technology, using the voltage generating device 5 to generate a high voltage to the spinning device 3, the spinning device 3 can spray the solution in the form of filaments, and the sprayed fine The silk will be collected in the collecting device 4.

Since FIG. 3B shows that the collecting device 4 is a collecting plate, a plurality of biological yarns 11 can be directly assembled into the hair growth-promoting dressing 1 of the present invention. It is worth noting that from the schematic diagram of the biological yarn manufacturing process shown in Fig. 4, it can be seen that if a collecting reel is used as the collecting device 4, the rolled biological yarn 11 can be further woven by weaving equipment. The dressing 1 for promoting hair growth.

Second manufacturing method

Engineers who have been involved in textile technology for a long time can know that the first manufacturing method described above is to use electro-spinning equipment to prepare a plurality of biological yarns 11, and then use weaving equipment to further weave the biological yarns 11 Cost of dressing 1 of the invention for promoting hair growth. Different from the first manufacturing method, the second manufacturing method uses spinning equipment to prepare a plurality of biological yarns 11. Please refer to FIGS. 5A to 5C, which are schematic diagrams showing the manufacturing process of the hair growth promoting dressing of the present invention. In FIG. 5A, the porous silicon dioxide nanoparticles 112 in the doped lanthanide metal are added to a polymer monomer solution 111a, and a plurality of plastic masterbatches 6 are obtained after polymerization and granulation processes. In FIG. 5B, the plurality of plastic masterbatches 6 are processed into a plurality of biological yarns 11 by using spinning equipment. Finally, in FIG. 5C, plural biological yarns 11 are used as plural warp yarns 1WA and plural weft yarns 1WE, and the plural warp yarns 1WA and plural weft yarns 1WE are woven into a biological fabric using a weaving equipment, namely The dressing 1 for promoting hair growth of the present invention.

Feasibility verification

In order to verify that the hair growth-promoting dressing 1 of the present invention does have the effect of promoting hair growth, the inventor of the present case completed related animal experiments. Before conducting animal experiments, a plurality of biological yarns 11 are produced by electrospinning equipment, and the plurality of biological yarns 11 are assembled in the collecting device 4 (ie, collecting plate) as shown in FIG. 3B Dressing to promote hair growth 1. In the animal experiment system, three six-week-old nude mice (BALB/c, female) were used, and the weight of these nude mice was 13 grams. The experimental method is: 1cm ² of hair growth-promoting dressing 1 is attached to the buttocks behind the right thigh of nude mice, wherein the hair-growth-promoting dressing 1 contains 2.5 mg of the hole dioxide in the doped lanthanide metal Silicon Nanoparticles (MSN) 112. In animal experiments, in order to make the hair growth-promoting dressing 1 stick to the hips of nude mice stably, a little bit of water was dropped on the hips of the nude mice before the hair-growth-promoting dressing 1 was attached.

It must be noted that the animal dose and adult dose can be converted according to the Body Surface Area (BSA) provided by the Food and Drug Administration (FDA). For example, biotechnologists can convert the adult dose and mouse dose of test samples according to the method of Estimating the maximum safe starting dose in initial clinical trials for therapeutics in adult healthy volunteers announced by the US Food and Drug Administration. . The calculation formula is shown as follows: Suggested dose per kilogram of body weight for mice = (Recommended dose for human body ÷ 60 kg) × 9.1.

Please refer to Figure 6, which shows an image of a nude mouse. In Figure 6, A1, B1, and C1 respectively represent 3 nude mice (BALB/c, female) used in animal experiments. In addition, we can observe through the image diagram in Fig. 6 that after seven days of continuous use of the hair growth-promoting dressing 1 of the present invention, the heads of nude mice A1 and B1 have obvious hair growth effects; and the growth is stimulated. The hair continued to fall off slightly until the twenty-first day. On the other hand, nude mice C1 showed obvious hair growth effects after 12 days of continuous use of the hair growth-promoting dressing 1 of the present invention.

Further, in order to confirm whether the hair growth-promoting dressing 1 of the present invention will have an adverse effect on the organism, the inventors of the present case recorded the weight of nude mice daily during the animal experiment. According to the data curve of time versus body weight shown in Figure 7, we can find that as the number of days of use of dressing 1 for promoting hair growth increases, the body weight of the three nude mice does not significantly decrease. Please continue to refer to Figure 8A, which shows a section of the skin tissue of the head of a nude mouse that has completed the animal experiment. At the same time, please continue to refer to Figure 8B, which shows a section of the head skin tissue of a normal nude mouse. Comparing Fig. 8A with Fig. 8B, it can be found that the nude mice attached to the hair growth-promoting dressing 1 of the present invention did not have serious head skin tissue damage or inflammation; and, it is worth noting that the nude mice that completed the animal experiment There is no significant difference between the head skin tissues of normal nude mice. Therefore, the experimental data in Fig. 7, Fig. 8A, and Fig. 8B confirm that the hair growth-promoting dressing 1 of the present invention does not cause toxic reactions or other adverse effects on organisms.

Therefore, animal experiments have confirmed that nude mice (BALB/c, female) with the hair growth-promoting dressing 1 of the present invention attached to the back buttocks of the right thigh can indeed show hair growth effects on their heads after seven days; among them, The hair growth-promoting dressing 1 contains at least 2.5 mg of the plurality of lanthanide-doped silicon dioxide nanoparticles 112 in the size of 1 cm 2. In other words, for an adult user, the hair growth-promoting dressing 1 must contain at least 16.48 mg of the plurality of lanthanide-doped silicon dioxide nanoparticles per square centimeter in size. 112. In this way, after the hair growth-promoting dressing 1 of the present invention is applied to the buttocks of the adult user, the hair growth effect can be shown on the head after seven days.

Second embodiment

1 and 2, the foregoing description discloses that the first embodiment of the hair growth-promoting dressing 1 of the present invention is a biological fabric woven from a plurality of biological yarns 11. Therefore, in order to improve the adhesion of the biological fabric, a small amount of secondary water was especially dripped on the hips of nude mice during animal experiments. For the reason of improving the adhesion of the fabric, as shown in FIG. 9 is a schematic perspective view of the second embodiment of the hair growth promoting dressing of the present invention, an adhesive layer 12 is bonded to the hair growth promoting dressing 1, To give it adhesive ability. On the other hand, considering that the purely biological fabric is weaker and easily damaged, the second embodiment further includes a base layer 10 for carrying and supporting the hair growth-promoting dressing 1.

The third embodiment

Please continue to refer to FIG. 10, which is a schematic perspective view showing the third embodiment of the hair growth promoting dressing of the present invention. We can learn from FIG. 10 that the third embodiment of the hair growth-promoting dressing 1 is designed to be OK. Among them, the dressing 1 for promoting hair growth is formed by interlacing a plurality of warp yarns 1WA and a plurality of weft yarns 1WE, and both the warp yarn 1WA and the weft yarn 1WE are a biological yarn 11 (see FIG. 2). As shown in FIG. 10, the dressing 1 for promoting hair growth is disposed on the base layer 10, and the adhesive layer 12 is also formed on the base layer 10. In particular, in order to improve the air permeability of the hair growth-promoting dressing 1 of the present invention, in the third embodiment, a plurality of air vents 101 are further provided on the base layer 10.

Fourth embodiment

Please continue to refer to FIG. 11, which is a schematic perspective view showing the fourth embodiment of the hair growth promoting dressing of the present invention. Comparing Figure 1 with Figure 11, it can be found that, different from the aforementioned first embodiment, the fourth embodiment of the hair growth-promoting dressing 1 is interlaced with a plurality of weft yarns 1WE and a plurality of warp yarns 1WA; wherein, the The plurality of weft yarns 1WE and the plurality of warp yarns 1WA each include a plurality of first yarns and a plurality of second yarns; wherein, the first yarn is a biological yarn 11, and the second yarn is a ( Natural or artificial) yarn 17. Referring to Fig. 2, the same as the first embodiment, the biological yarn 11 in the fourth embodiment includes a polymer sheath 111 and a plurality of silica nanoparticles doped with lanthanide metal holes ( Mesoporous silica nanoparticles, MSN) 112; wherein the porous silica nanoparticles 112 in the doped lanthanide metal are represented by the chemical formula SiO ₂ ^x :Eu ^y Gd ^z , and they are doped or coated in the In the polymer sheath 111.

Engineers familiar with textile technology can easily infer that the yarn 17 can be artificial yarn or natural yarn, and it can be any of the following: gelatin/trifluoroethanol composite yarn, gelatin/trifluoroethylene Ethanol/polycaprolactone composite yarn, gelatin/trifluoroethanol/polylactic acid yarn, polyester yarn, polyurethane yarn, polyvinyl chloride yarn, polypropylene yarn, polyamide yarn, both of the above , Or a combination of two or more of the above. Moreover, it is worth noting that the biological fabric of the fourth embodiment is woven with biological yarns 11 and (general) yarns 17, and by adjusting the plurality of biological yarns 11 and the plurality of yarns The method of mixing yarn ratio between 17 can make the production cost of the biological fabric of the fourth embodiment lower than that of the first embodiment. For example, let the plurality of biological yarns 11 have a ratio ranging from 20% to 55% among the plurality of warp yarns 1WA and the plurality of weft yarns 1WE. However, it must be emphasized that the biological fabric of the fourth embodiment can also be further processed into the second embodiment of the hair growth-promoting dressing 1 shown in FIG. 9 or the hair-promoting dressing 1 shown in FIG. 10 The third embodiment of the growing dressing 1.

Thus, the above system has completely and clearly explained the composition and efficacy of the hair growth-promoting dressing 1 of the present invention. From the above, it can be known that the present invention has the following advantages:

(1) Different from the commercially available hair growth composition, the formula is complicated and expensive. The inventor of the present invention specially used electrospinning or spinning technology to mix a plurality of silica nanoparticles doped with lanthanide metal holes ( MSN) 112 and a polymer material are processed into a plurality of biological yarns 11, and then the plurality of biological yarns 11 are woven into a biological fabric with a weaving equipment, which is used as a hair growth-promoting dressing 1 of the present invention. It is conceivable that compared with commercially available hair growth compositions, the hair growth promoting dressing 1 of the present invention has the absolute advantage of low manufacturing cost. In addition, the experimental results also confirmed that after seven days of continuous use of the hair growth-promoting dressing 1 of the present invention, the heads of nude mice have obvious hair growth effects. Obviously, compared to the commercially available hair growth composition that must be used for at least four months for a long time to show the effect of hair growth, the hair growth-promoting dressing 1 of the present invention exhibits an immediate hair growth effect.

It must be emphasized that the above detailed description is a specific description of possible embodiments of the present invention, but this embodiment is not intended to limit the scope of the present invention. Any equivalent implementation or modification without departing from the technical spirit of the present invention, All should be included in the patent scope of this case.

＜The invention＞1‧‧‧Hair growth-promoting dressing 1WA‧‧‧Warp yarn 1WE‧‧‧Weft yarn 11‧‧‧Biological yarn 111‧‧‧Polymer sheath 112‧‧‧Doped with holes in lanthanide metals Silicon dioxide nanoparticle 11a‧‧‧Gelatin raw material 11b‧‧‧Solvent 2‧‧‧Reaction flask 3‧‧‧Spinner 4‧‧‧Collection device 5‧‧‧Voltage generator 111a‧‧‧Polymer sheet Body solution 6‧‧‧Plastic masterbatch A1‧‧‧Nude mouse B1‧‧‧Nude mouse C1‧‧‧Nude mouse12‧‧‧Adhesive layer 10‧‧‧Base layer 101‧‧‧Vent 17‧‧‧Yarn line

＜Accustomed knowledge＞ None

Fig. 1 is a schematic perspective view showing the first embodiment of a hair growth-promoting dressing of the present invention; Fig. 2 is a cross-sectional view showing a biological yarn; Figs. 3A to 3B are a schematic diagram showing the manufacturing process of the biological yarn; Figure 4 shows a schematic diagram of the production process of biological yarn; Figures 5A to 5C show a schematic diagram of the production process of the hair growth-promoting dressing of the present invention; Figure 6 shows an image of a nude mouse; Figure 7 shows data of time versus weight Fig. 8A shows a section of the skin tissue of the head of a nude mouse that has completed the animal experiment; Fig. 8B shows a section of the tissue of the head of a normal nude mouse; Fig. 9 shows the section of the hair growth-promoting dressing of the present invention A schematic perspective view of the second embodiment; Fig. 10 is a schematic perspective view showing the third embodiment of the hair growth promoting dressing of the present invention; and Fig. 11 is a schematic view showing the fourth embodiment of the hair growth promoting dressing of the present invention Sexual stereogram.

1‧‧‧Dressing to promote hair growth

1WA‧‧‧Warp

1WE‧‧‧Weft

Claims (8)

A dressing for promoting hair growth is formed by interlacing a plurality of warp yarns and a plurality of weft yarns; wherein, the warp yarn and the weft yarn are both a biological yarn, and the biological yarn system includes: a polymer Sheath; and a plurality of doped lanthanide-based metal pores in the silicon dioxide nanoparticle, which are doped or coated in the polymer sheath; wherein, the doped lanthanide-based metal pores in the silicon dioxide nanoparticle The rice particles include the chemical formula SiO ₂ ^x : Eu ^y Gd ^z ; where x, y and z are weight percentages, and x is between 99wt% and 99.8wt%, and y and z are both between 0.1wt% and 0.5 wt%; wherein the diameter of the porous silica nanoparticles in the doped lanthanide metal is less than 100nm, and the hair growth promoting dressing contains at least 16.48mg per 1 cm2 The plurality of silica nanoparticles doped with holes in the lanthanide series metal. The hair growth-promoting dressing described in item 1 of the scope of the patent application further includes: a base layer for carrying and supporting a biological fabric formed by interlacing the plurality of warp yarns and the plurality of weft yarns; and An adhesive layer is bonded to the biological fabric to provide adhesiveness of the biological fabric. The dressing for promoting hair growth as described in item 1 of the scope of patent application, wherein the polymer sheath can be any of the following: gelatin/trifluoroethanol composite sheath, gelatin/trifluoroethanol/polycaprolactone composite sheath, Gelatin/trifluoroethanol/polylactic acid sheath, polyester sheath, polyurethane sheath, polyvinyl chloride sheath, polypropylene sheath, polyamide sheath, a combination of the above two, or a combination of two or more of the above. The dressing for promoting hair growth as described in item 2 of the scope of patent application, wherein at least one adhesive layer is further provided on the base layer. A dressing for promoting hair growth is formed by interlacing a plurality of warp yarns and a plurality of weft yarns; wherein, the plurality of warp yarns and the plurality of weft yarns both include a plurality of first yarns and a plurality of second yarns; wherein , The first yarn is a biological yarn, and the second yarn is a natural yarn or an artificial yarn; the biological yarn includes: a polymer sheath; and a plurality of doped lanthanum Silica nanoparticles with holes in the metal are doped or coated in the polymer sheath; wherein, the silicon dioxide nanoparticles with holes in the doped lanthanide metal comprise the chemical formula SiO ₂ ^x : Eu ^y Gd ^z ; where x, y and z are weight percentages, and x is between 99wt% and 99.8wt%, and y and z are both between 0.1wt% and 0.5wt%; wherein, the The diameter of the porous silica nanoparticle in the doped lanthanide metal is less than 100nm, and the hair growth-promoting dressing contains at least 16.48 mg of the plurality of doped lanthanide metals per 1 cm² in size. Silica nano particles with holes in it. The hair growth-promoting dressing described in item 5 of the scope of the patent application further includes: a base layer for carrying and supporting a biological fabric formed by interlacing the plurality of warp yarns and the plurality of weft yarns; and An adhesive layer is bonded to the biological fabric to provide adhesiveness of the biological fabric. The dressing for promoting hair growth as described in item 5 of the scope of patent application, wherein the polymer sheath can be any of the following: gelatin/trifluoroethanol composite sheath, gelatin/trifluoroethanol/polycaprolactone composite sheath, Gelatin/trifluoroethanol/polylactic acid composite sheath, polyester sheath, polyurethane sheath, polyvinyl chloride sheath, polypropylene sheath, polyamide sheath, a combination of the above two, or a combination of two or more of the above. The dressing for promoting hair growth as described in item 5 of the scope of patent application, wherein the yarn is a natural yarn or an artificial yarn, and it can be any of the following: gelatin/trifluoroethanol composite yarn, Gelatin/trifluoroethanol/polycaprolactone composite yarn, gelatin/trifluoroethanol/polylactic acid composite yarn, polyester yarn, polyurethane yarn, polyvinyl chloride yarn, polypropylene yarn, polyamide yarn Line, a combination of the above two, or a combination of two or more of the above.

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