TWI704918B - 含有細胞周期蛋白抑制劑的藥物製劑及其製備方法 - Google Patents
含有細胞周期蛋白抑制劑的藥物製劑及其製備方法 Download PDFInfo
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- TWI704918B TWI704918B TW104136656A TW104136656A TWI704918B TW I704918 B TWI704918 B TW I704918B TW 104136656 A TW104136656 A TW 104136656A TW 104136656 A TW104136656 A TW 104136656A TW I704918 B TWI704918 B TW I704918B
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410623810.2 | 2014-11-07 | ||
| CN201410623810.2A CN105616418A (zh) | 2014-11-07 | 2014-11-07 | 含有细胞周期蛋白抑制剂的药物制剂及其制备方法 |
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| TW201617082A TW201617082A (zh) | 2016-05-16 |
| TWI704918B true TWI704918B (zh) | 2020-09-21 |
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| EP (1) | EP3216450B1 (ja) |
| JP (1) | JP6682739B2 (ja) |
| CN (2) | CN105616418A (ja) |
| TW (1) | TWI704918B (ja) |
| WO (1) | WO2016070834A1 (ja) |
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| US10449195B2 (en) | 2016-03-29 | 2019-10-22 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical formulation of palbociclib and a preparation method thereof |
| CN110314148A (zh) * | 2019-05-07 | 2019-10-11 | 安徽金太阳生化药业有限公司 | 一种磷酸氢钙片的制备方法 |
| WO2022063119A1 (zh) * | 2020-09-24 | 2022-03-31 | 南京济群医药科技股份有限公司 | 一种羟乙磺酸哌柏西利的组合物及药物 |
| CN114306245A (zh) | 2020-09-29 | 2022-04-12 | 深圳市药欣生物科技有限公司 | 无定形固体分散体的药物组合物及其制备方法 |
| WO2024104448A1 (zh) * | 2022-11-18 | 2024-05-23 | 轩竹生物科技股份有限公司 | CDKs抑制剂的药物组合物及制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050059670A1 (en) * | 2003-07-11 | 2005-03-17 | Pfizer Inc | Isethionate salt of a selective CKD4 inhibitor |
| CN101001857A (zh) * | 2002-01-22 | 2007-07-18 | 沃尼尔·朗伯有限责任公司 | 2－(吡啶－2－基氨基)－吡啶并[2,3－d]嘧啶－7－酮 |
| TW201129386A (en) * | 2009-11-05 | 2011-09-01 | Fmc Corp | Microcrystalline cellulose and calcium phosphate compositions useful as pharmaceutical excipients |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
| EP2076249A2 (en) * | 2006-10-27 | 2009-07-08 | FMC Corporation | Dry granulation binders, products, and use thereof |
| SG11201505680RA (en) * | 2013-02-21 | 2015-09-29 | Pfizer | Solid forms of a selective cdk4/6 inhibitor |
| WO2016030439A1 (en) * | 2014-08-28 | 2016-03-03 | Ratiopharm Gmbh | Method of producing palbociclib and pharmaceutical compositions comprising the same |
| BR112017025398A2 (pt) * | 2015-06-04 | 2018-08-07 | Pfizer Inc. | formas de dosagem sólidas de palbociclib |
| CN104892604B (zh) * | 2015-06-19 | 2016-08-24 | 北京康立生医药技术开发有限公司 | 一种cdk4抑制剂的合成方法 |
| CN105213322A (zh) * | 2015-10-30 | 2016-01-06 | 南京正大天晴制药有限公司 | 一种干法制粒工艺制备的药物组合物 |
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- 2015-11-06 TW TW104136656A patent/TWI704918B/zh not_active IP Right Cessation
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101001857A (zh) * | 2002-01-22 | 2007-07-18 | 沃尼尔·朗伯有限责任公司 | 2－(吡啶－2－基氨基)－吡啶并[2,3－d]嘧啶－7－酮 |
| US20050059670A1 (en) * | 2003-07-11 | 2005-03-17 | Pfizer Inc | Isethionate salt of a selective CKD4 inhibitor |
| TW201129386A (en) * | 2009-11-05 | 2011-09-01 | Fmc Corp | Microcrystalline cellulose and calcium phosphate compositions useful as pharmaceutical excipients |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106794183A (zh) | 2017-05-31 |
| US20180280392A1 (en) | 2018-10-04 |
| JP6682739B2 (ja) | 2020-04-15 |
| JP2017532347A (ja) | 2017-11-02 |
| CN105616418A (zh) | 2016-06-01 |
| EP3216450B1 (en) | 2021-09-22 |
| EP3216450A8 (en) | 2018-02-07 |
| EP3216450A4 (en) | 2018-06-13 |
| TW201617082A (zh) | 2016-05-16 |
| CN106794183B (zh) | 2021-06-18 |
| WO2016070834A1 (zh) | 2016-05-12 |
| EP3216450A1 (en) | 2017-09-13 |
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