TWI691337B - 靶向表現egfr的腫瘤的化合物及組合物 - Google Patents

靶向表現egfr的腫瘤的化合物及組合物 Download PDF

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Publication number
TWI691337B
TWI691337B TW104100852A TW104100852A TWI691337B TW I691337 B TWI691337 B TW I691337B TW 104100852 A TW104100852 A TW 104100852A TW 104100852 A TW104100852 A TW 104100852A TW I691337 B TWI691337 B TW I691337B
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Taiwan
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cancer
alkyl
antibody
cells
tumor
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TW104100852A
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English (en)
Chinese (zh)
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TW201611847A (en
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立新 李
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英屬開曼群島商博笛生物科技有限公司
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Priority claimed from CN201410011262.8A external-priority patent/CN104861063A/zh
Priority claimed from CN201410011362.0A external-priority patent/CN104861064A/zh
Priority claimed from CN201410011324.5A external-priority patent/CN104861067A/zh
Application filed by 英屬開曼群島商博笛生物科技有限公司 filed Critical 英屬開曼群島商博笛生物科技有限公司
Publication of TW201611847A publication Critical patent/TW201611847A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • A61K47/6857Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from lung cancer cell
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TW104100852A 2014-01-10 2015-01-09 靶向表現egfr的腫瘤的化合物及組合物 TWI691337B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CN201410011262.8A CN104861063A (zh) 2014-01-10 2014-01-10 靶向her2阳性肿瘤的化合物和组合物
CN201410011362.0A CN104861064A (zh) 2014-01-10 2014-01-10 靶向表达egfr的肿瘤的化合物和组合物
CN201410011362.0 2014-01-10
CN201410011324.5A CN104861067A (zh) 2014-01-10 2014-01-10 用于免疫疗法的化合物和组合物
CN201410011324.5 2014-01-10
CN201410011262.8 2014-01-10

Publications (2)

Publication Number Publication Date
TW201611847A TW201611847A (en) 2016-04-01
TWI691337B true TWI691337B (zh) 2020-04-21

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Application Number Title Priority Date Filing Date
TW104100854A TWI674904B (zh) 2014-01-10 2015-01-09 用於免疫療法的化合物及組合物
TW104100852A TWI691337B (zh) 2014-01-10 2015-01-09 靶向表現egfr的腫瘤的化合物及組合物
TW104100853A TWI691338B (zh) 2014-01-10 2015-01-09 靶向her2陽性腫瘤的化合物及組合物

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