TWI652074B - Anti-mold agent composition, anti-mold spray product and anti-mildew method - Google Patents

Abstract

Provided is an antifungal agent composition capable of exhibiting an excellent antifungal effect among organic antifungal agents.

A fungicide composition comprising: a triazole-based compound, and ethylene glycol, and an alcohol; the triazole-based compound is Dekli; the ethylene glycol is propylene glycol and / or 1,3-butanediol; the alcohol is ethanol and The mixing ratio (weight ratio) of 2-propanol, triazole-based compound and ethylene glycol is 1:10 to 1: 0.5, and it further contains a deodorizing component.

Description

Antifungal agent composition, antifungal spray product and antifungal method

The present invention relates to a mold preventive composition for preventing the generation of mold, a spray product for mold prevention, and a method for preventing mold.

In recent years, houses are in an environment with high air-tightness, and moisture accumulates indoors and is prone to mold. Mildew prefers water, moderate temperatures, and places where nutrients are present. Curtains, wallpapers, closets that are prone to dew in ordinary houses, and closets, or mattresses that sweat easily during bedtime can be said to be mildewy places. Therefore, countermeasures against the occurrence of mold in such places are expected.

As a method for preventing the generation of mold, generally, an antifungal agent is applied to an object. As a conventional antifungal agent, for example, a person using silver (for example, refer to Patent Document 1), a person using a photocatalyst (for example, refer to Patent Document 2), and the like are known. These antifungal agents are inorganic antifungal agents. On the other hand, organic antifungal agents are also known. For example, there are users of antifungal agents using triazole compounds as wood (for example, refer to Patent Document 3).

[Patent Document 1]: Japanese Patent Laid-Open No. 2007-31857

[Patent Document 2]: Japanese Patent Laid-Open No. 2001-245781

[Patent Document 3]: Japanese Patent Application Publication No. 2012-71471

The inorganic type antifungal agent represented by patent document 1 or patent document 2 has the disadvantage that it is easy to discolor. Therefore, there are cases where it is not suitable for household items such as curtains, wallpapers, mattresses, and the like. Although the organic type antifungal agent represented by Patent Document 3 has few problems of discoloration, there is still room for improvement in efficacy.

Therefore, the present inventors paid particular attention to the organic antifungal agent having good compatibility with household products, and tried to establish a new antifungal technology. That is, it is an object of the present invention to provide a mildew-proofing agent composition capable of exhibiting a mildew-proofing effect that is superior to that of conventional mildew-proofing agents. Furthermore, the object is to provide a mold-proof spray product which is excellent in use by using such a mold-proof agent composition. Furthermore, it aims at providing the mold prevention method using the spray product for mold prevention.

The characteristic composition of the antifungal agent composition related to the present invention for solving the above-mentioned problems is that the antifungal agent composition contains a triazole compound, glycol, ethanol, and / Or 2-propanol.

The present inventors have re-discovered that if ethylene glycol is used in combination with a triazole-based compound, the antifungal property of the triazole-based compound is enhanced by ethylene glycol, and if an alcohol is used in combination, the triazole-based compound is moderately dispersed. Therefore, compared with the case where a triazole-based compound is used alone, the antifungal agent composition according to the present constitution can exhibit a better antifungal effect.

The antifungal agent composition according to the present composition is particularly suitable as a suitable alcohol by using ethanol and / or 2-propanol to disperse a triazole compound. Good person.

In the antifungal agent composition related to the present invention, the triazole compound is preferably tebuconazole.

The mildew-proofing agent composition according to the present composition, as a suitable triazole-based compound, exhibits excellent mildew-proofing effects by using Dekly.

In the antifungal agent composition related to the present invention, the aforementioned ethylene glycol is preferably propylene glycol and / or 1,3-butylene glycol.

The antifungal agent composition according to the present composition is particularly suitable for the use of propylene glycol and / or 1,3-butanediol as a suitable ethylene glycol to enhance the antifungal effect of the triazole-based compound.

In the antifungal agent composition related to the present invention, the compounding ratio (weight ratio) of the triazole compound and the ethylene glycol is preferably 1:10 to 1: 0.5.

According to the antifungal agent composition of this configuration, since the compounding ratio (weight ratio) of the triazole-based compound to ethylene glycol is set to an appropriate range, the anti-mildew of the triazole-based compound can be effectively enhanced by ethylene glycol. Sex.

The antifungal agent composition related to the present invention is selected from the group consisting of Cladosporium sp., Alternaria sp., Fusarium sp., And Penicillium ( Penicillium sp.), Aspergillus, Eurotium sp., And Wallemia sp.

The antifungal composition according to the present composition can prevent Mycosporium, Streptomyces, Fusarium, Penicillium, Pseudomonas, Bacillus and Arthrobacter, which are easily produced in normal living space, can be highly resistant to mildew in daily use. effect. In addition, since the above-mentioned mold exhibits a dark color to a dark color, the fiber product or the paper product is imparted with mold resistance through the antifungal agent composition of the present composition, which can give consumers an excellent feeling of use.

The antifungal agent composition related to the present invention is preferably used for curtains.

According to the antifungal agent composition of this structure, the mold | fever which propagates in curtains which has been a problem especially in the past can be effectively suppressed.

The feature of the anti-mildew spray product related to the present invention for solving the above-mentioned problems is that the anti-mildew spray product is formed by encapsulating a medicament containing any of the anti-fungal agent composition and water in a spray container The content of the ethanol and / or 2-propanol in the medicine is set to 20 to 60% by weight.

The anti-mildew spray product according to the present structure contains the anti-mold agent composition of the present invention, so that the anti-mold property of the triazole-based compound is enhanced by ethylene glycol, and the triazole-based compound is moderately dispersed by the alcohol. It can be used as an anti-mold product that is better than before. In addition, since the content of the alcohol in the medicine enclosed in the spray container is set to 20 to 60% by weight, the triazole-based compound is completely dissolved in the medicine without precipitating. As a result, the correct amount of the medicine can be given according to the number of sprays Process the object. Furthermore, if it is the said alcohol content, since a suitable spray pattern is formed, a chemical | medical agent can be adhered to a process target everywhere.

The mold prevention method related to the present invention for solving the above-mentioned problems is characterized in that it is a mold prevention method in which the aforementioned medicine is sprayed onto a treatment object from the aforementioned mildew spray product, and the aforementioned medicine is attached to the treatment object At least part of the surface.

According to the anti-mold method of this configuration, since the agent is adhered to at least a part of the surface of the object to be treated by using the anti-mold spray product of the present invention, and the object to be treated is subjected to anti-mold treatment, the generation of mold can be effectively prevented .

The antifungal agent composition, antifungal spray product, and antifungal method of the present invention will be described below. However, the present invention is not intended to be limited to the embodiments described below.

The present inventors have re-discovered that when a triazole-based compound that has been conventionally used as an anti-mold agent for wood is used as a general household anti-mold agent, if ethylene glycol is used in combination with the triazole-based compound, The antifungal property is enhanced, and when an alcohol is used in combination, the triazole-based compound is moderately dispersed, and a new antifungal agent composition is conceived based on this knowledge. The details will be described in the examples described later. The mold-proofing agent composition of the present invention is enclosed in a spray container together with water to constitute the spray-proof product for mold-proofing of the present invention. Excellent anti-mildew effect. In addition, the term "mildew prevention effect" in the present specification means that the occurrence of mildew is mainly to prevent the occurrence of mildew, and the elimination of the generated mildew or the suppression of the expansion of the generated mildew is also included in the mildew prevention effect. As an antifungal composition which can be used by the present invention (Spray products for anti-mildew) The types of molds that inhibit reproduction include, for example, mycosporium (so-called Aspergillus niger), Alternaria spp., Fusarium, Penicillium, Pseudomonas, and loose capsule Bacteria, nodules and so on. These molds are molds that are easily generated in daily living spaces such as bedrooms, living rooms, living rooms, bathrooms, toilets, kitchens, etc., and the appearance of the molds is dark to strong. Therefore, if the molds are given by the antifungal composition of the present invention The mildew resistance of the fibrous products (such as curtains) or paper products (such as wallpaper) existing in the above-mentioned living space is prevented or greatly improved due to mildew, and can give consumers a good feeling of use. In particular, if the product of the present invention is applied to a curtain installed in a bedroom, a living room, or a living room, consumers can get a sense of cleanliness or peace of mind.

<Fungicide Composition>

The main components of the antifungal agent composition of the present invention include a triazole compound, ethylene glycol, and alcohol.

Examples of the triazole-based compound include dekli, imibenconazole-db, triadimenol, paclibutrazol, propiconazole, hexaconazole, and penconazole ), Myclobutanil, metconazole (registered trademark), etc. Of these compounds, Klee is preferred. These triazole compounds may be used alone or in combination.

Examples of the ethylene glycol include ethylene glycol, propylene glycol, 1,3-butanediol, pentylene glycol, and 1,2-hexanediol. Among these compounds, propylene glycol and 1,3-butanediol are preferred. In addition, these glycols can be used alone or in combination. Several uses.

Examples of the alcohol include methanol, ethanol, 1-propanol, 2-propanol, butanol, pentanol, and hexanol. Among these compounds, ethanol and 2-propanol are preferred. These alcohols may be used singly or in combination.

The antifungal composition of the present invention may contain a deodorizing component, a fragrance, a pH adjuster, etc. in addition to the triazole-based compound, ethylene glycol, and alcohol listed above. For example, if a flavonoid is contained as a deodorant component, it can suppress an uncomfortable odor generated in a moisture-loving environment that molds favor.

The antifungal agent composition of the present invention is compounded with each of the components listed above at an appropriate weight ratio, and further adjusted by adding water so that the concentration of each component becomes appropriate.

When blending the components listed above, the blending ratio (weight ratio) of the triazole compound and ethylene glycol is preferably adjusted to 1:10 to 1: 0.5, and more preferably adjusted to 1:10 to 1: 1. In the case where the mixing ratio of the triazole compound and ethylene glycol is less than 1:10 (that is, the mixing amount of the triazole compound to the ethylene glycol is less than 1/10), because the triazole compound is insufficient Therefore, there is a possibility that the anti-mold effect cannot be fully exerted. When the compounding ratio of the triazole compound and ethylene glycol exceeds 1: 0.5 (that is, when the compounding amount of the triazole compound is more than 2 times the amount of ethylene glycol), it may not be possible due to insufficient ethylene glycol There is a possibility that the mold-proof property of the triazole-based compound is sufficiently enhanced.

When water is added, the prepared medicine (a mixture of a triazole compound, ethylene glycol, alcohol, and water, and containing other components as necessary) The alcohol content is set to 20 to 60% by weight. Within this range, the triazole-based compound can be completely dissolved in the pharmaceutical without precipitating. Therefore, it becomes easy to apply a correct amount of a medicine to a treatment target. Moreover, when the spray product for mildew prevention mentioned later is comprised, since a suitable spray pattern is formed, a chemical | medical agent can be adhered to a process target everywhere.

<Spray products for antifungal agents>

A preferred product form of the antifungal composition of the present invention is a spray product. For example, the above-mentioned agent (at least a mixture of the antifungal agent composition of the present invention and water) is enclosed in a spray container to constitute the antifungal spray product of the present invention. As a spray container, it is preferable to provide a trigger-type sprayer. The medicine enclosed in the spray container is as described above, and the content of the alcohol in the medicine is set to 20 to 60% by weight. According to this, when the spray is sprayed, the drug diffuses into a substantially circular shape, and a spray pattern in which the application amount of the drug to be applied to the object to be processed becomes slightly uniform can be formed. In addition, it is possible to apply a correct amount of the medicine to the treatment target in accordance with the number of sprays.

<Anti-mold method>

The anti-mildew method of the present invention can be carried out using the aforementioned anti-mildew spray product. Specifically, the operator holds the trigger of the anti-mildew spray product and sprays the medicine toward the surface of the object to be treated. Thereby, the chemical | medical agent adheres to the surface of a processing target object. Further, the agent is dried as necessary. The spraying and drying of the medicine may be repeated several times. The spraying amount of the medicine is preferably 9.0 to 13.5 g / m ² to the object to be treated. When the spraying amount of the medicine is less than 9.0 g / m ² , the adhesion amount of the triazole-based compound and ethylene glycol as an active ingredient is insufficient, and the antifungal effect may not be sufficiently provided due to the raw material of the treatment object. When the spraying amount of the medicine exceeds 13.5 g / m ² , the object to be treated may still feel sticky after drying. When a series of mildew-proof treatments are completed on the treatment target, an excellent mildew-proof effect is exerted on the treatment target, and the generation of mold can be effectively prevented for a long period of time.

[Example]

In order to confirm the performance of the antifungal agent composition of the present invention and the conditions during use, a antifungal test was performed on the curtain, and the appearance and spray pattern of the chemical solution were also confirmed. In the preparation of the antifungal agent composition, Dekli was used as a triazole compound, propylene glycol and / or 1,3-butanediol were used as ethylene glycol, and ethanol was used as an alcohol to add ion exchange water. ) As medicine. The following chemicals were used for each component of the antifungal agent composition.

． Dekli (Product name: BiosaidoR-BP20, manufactured by TAISHO TECHNOS Co., Ltd.)

． Propylene glycol (Industrial propylene glycol, manufactured by ADEKA Corporation)

． 1,3-butanediol (1,3-butanediol for industrial use, manufactured by DAICEL Co., Ltd.)

． Ethanol (95% by weight ethanol for industrial use, manufactured by Japan Synthetic Alcohol Co., Ltd.)

This medicinal solution was sealed in a spray container (part number: T014, manufactured by CANYON Co., Ltd.) equipped with a trigger sprayer, and constituted a mildew-proof spray product of the present invention.

<Prescription of medicinal solution>

Formulations for each liquid medicine prepared in Examples 1 to 7 and Comparative Examples 1 to 3 As follows.

[Example 1]

0.05 parts by weight (part by weight), 20 parts by weight of ethanol (converted to 100% by weight, the same applies to the following examples and comparative examples), and 0.5 parts by weight of propylene glycol were mixed, and ion-exchanged water was added to the mixture. A chemical solution of 100 parts by weight was prepared as a whole. The compounding ratio (weight ratio) of Dekli to propylene glycol in Example 1 was 1:10. The content of ethanol in the drug was 20% by weight.

[Example 2]

0.1 parts by weight of Keli, 40 parts by weight of ethanol and 0.5 parts by weight of propylene glycol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli to propylene glycol in Example 2 was 1: 5. The content of ethanol in the drug was 40% by weight.

[Example 3]

0.2 parts by weight of Keli, 60 parts by weight of ethanol, and 0.2 parts by weight of 1,3-butanediol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli to 1,3-butanediol in Example 3 was 1: 1. The content of ethanol in the drug was 60% by weight.

[Example 4]

0.5 parts by weight of Keli, 50 parts by weight of ethanol, 0.5 parts by weight of propylene glycol and 0.5 parts by weight of 1,3-butanediol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli with propylene glycol and 1,3-butanediol in Example 4 was 1: 2. The content of ethanol in the drug was 50% by weight.

[Example 5]

0.1 parts by weight of Keli, 40 parts by weight of ethanol and 0.05 parts by weight of propylene glycol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli to propylene glycol in Example 5 was 1: 0.5. The content of ethanol in the drug was 40% by weight.

[Example 6]

0.2 parts by weight of Keli, 65 parts by weight of ethanol and 0.1 parts by weight of propylene glycol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli to propylene glycol in Example 6 was 1: 0.5. The content of ethanol in the drug was 65% by weight.

[Example 7]

0.1 parts by weight of Keli, 10 parts by weight of ethanol and 3 parts by weight of 1,3-butanediol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. The compounding ratio (weight ratio) of Dekli and 1,3-butanediol in Example 7 was 1:30. The content of ethanol in the drug was 10% by weight.

[Comparative Example 1]

Ion-exchanged water was added to 20 parts by weight of ethanol to prepare 100 parts by weight of a chemical solution. That is, Comparative Example 1 is a medicinal solution that does not contain Derekil and ethylene glycol (propylene glycol and / or 1,3-butanediol), and is equivalent to the mixture obtained by removing Derekil and propylene glycol from the prescription of Example 1.

[Comparative Example 2]

0.1 parts by weight of Keli and 0.5 parts by weight of propylene glycol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. That is, Comparative Example 2 is a medicinal solution containing no ethanol, and is equivalent to the mixture obtained by removing ethanol from the prescription of Example 2.

[Comparative Example 3]

0.1 parts by weight of Dekly and 30 parts by weight of ethanol were mixed, and ion-exchanged water was added to the mixture to prepare 100 parts by weight of a chemical solution. That is, Comparative Example 3 is a chemical solution containing no ethylene glycol (propylene glycol and / or 1,3-butanediol).

<Appearance of medicinal solution>

The external appearances of the chemical solutions of Examples 1 to 7 and Comparative Examples 1 to 3 were visually confirmed. The evaluation criteria of the appearance are shown below.

○: No precipitate was recognized in the medicinal solution, and it was colorless and transparent.

×: Precipitation and turbidity were recognized in the medicinal solution.

<Anti-mold effect>

A glucose peptone medium as a mold culture medium was sprayed onto a lace curtain (spray area: 10 cm × 10 cm) and air-dried for 1 hour. The spray product of the antifungal agent of the present invention sealed with the medicinal solution of Examples 1 to 7 was sprayed onto the dried lace curtain (spraying amount: 9.9 to 11.1 g / m ² ), and air-dried for 1 hour. The same operation was performed on the spray products in which the chemical solutions of Comparative Examples 1 to 3 were enclosed. Next, a certain number of molds (mycosporium (black mold), penicillium) were attached to the lace curtain, and then sprayed with a sprayer, and stored in a desiccator maintained at 90% humidity and cultured Got mold. Then, the state of mold generation after 1 week had been confirmed. The evaluation criteria for the occurrence of mold are shown below.

：: Mold was not generated at all.

(Circle): A mildew arises, but there is no problem in appearance.

△: It was confirmed that some mildew was generated.

×: The occurrence of mold was clearly recognized.

<Spray pattern>

The spray products for the antifungal agent of the present invention sealed with the chemical liquids of Examples 1 to 7 and the spray products sealed with the chemical liquid of Comparative Examples 1 to 3 were sprayed once at a distance of 20 cm from the plastic plate, and were visually confirmed to form on The shape of the spray pattern of the plastic plate was measured using a scale. The evaluation criteria of the shape of a spray pattern are as follows.

(Circle): The shape which is a round shape is uniform, and there is no unevenness.

×: Uneven and uneven shape.

<Test result>

The test results of Examples 1 to 7 and Comparative Examples 1 to 3 are shown in Table 1 below along with the prescription of the medicinal solution.

[Table 1]

Regarding the spray products for antifungal agents using the medicinal solution of Examples 1 to 7, the appearance of the medicinal solution was not recognized as a precipitate in the medicinal solution, remained colorless and transparent, and no problem was seen. The mildew-proof effect is that although mildew is generated, it is not a problem in practical use. In particular, in Examples 1 to 4, mold was not generated at all, and excellent mold-proof effects were confirmed. It is suggested that it is particularly effective to set the content of ethanol in the drug to 20 to 60% by weight. Although the spray pattern of Examples 6 and 7 was slightly uneven in shape, the spray pattern was good as a whole.

On the other hand, the spray products using the chemical liquids of Comparative Examples 1 to 3 cannot coexist in the appearance and antifungal effect of the chemical liquid, and the performance and the conditions during use are also inferior to those of Examples 1 to 7 (products of the present invention).

The antifungal agent composition, antifungal spray product, and antifungal method of the present invention can be used for textile materials such as curtains, clothing, bedding, mattresses, pillows, etc., or building materials such as closet walls and wallpaper.

Claims (8)

An antifungal agent composition, comprising: a triazole compound, ethylene glycol, and ethanol and / or 2-propanol. For example, the antifungal composition of the first patent application scope, wherein the triazole compound is tebuconazole. For example, in the application of the anti-fungal agent composition of item 1 or item 2, the ethylene glycol is propylene glycol and / or 1,3-butanediol. For example, in the application of the antifungal agent composition of item 1 or item 2, the compounding ratio (weight ratio) of the triazole compound and the ethylene glycol is 1: 10 ~ 1: 0.5. For example, the antifungal agent composition of the scope of application for item 1 or item 2 is selected from the group consisting of mycosporium, streptomyces, Fusarium, penicillium, taenia, cysticerium and nodules At least one kind of mold in a group of bacteria is targeted. For example, the application of the anti-mildew composition of the first or second patent scope, which is used for curtains. A mildew-resistant spray product is obtained by sealing a medicine containing the mildew-resistant agent composition and water in any of claims 1 to 6 in a spray container, and the ethanol and / or 2- The content of propanol is set to 20 to 60% by weight. A method for preventing mildew, spraying the medicine to a treatment target from a spray product for mildew prevention in a scope of application for a patent, and attaching the medicine to at least a part of a surface of the treatment target.