TWI553000B - 反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法 - Google Patents

反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法 Download PDF

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Publication number
TWI553000B
TWI553000B TW103102539A TW103102539A TWI553000B TW I553000 B TWI553000 B TW I553000B TW 103102539 A TW103102539 A TW 103102539A TW 103102539 A TW103102539 A TW 103102539A TW I553000 B TWI553000 B TW I553000B
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TW
Taiwan
Prior art keywords
compound
formula
liver
hydroxymethyl
trans
Prior art date
Application number
TW103102539A
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English (en)
Chinese (zh)
Other versions
TW201529564A (zh
Inventor
潘敏雄
張誌益
吳嘉利
徐榜奎
Original Assignee
綠茵生技股份有限公司
潘敏雄
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Publication date
Application filed by 綠茵生技股份有限公司, 潘敏雄 filed Critical 綠茵生技股份有限公司
Priority to TW103102539A priority Critical patent/TWI553000B/zh
Priority to CN201410099171.4A priority patent/CN104803966A/zh
Priority to KR1020140036865A priority patent/KR101644450B1/ko
Priority to JP2014085186A priority patent/JP2015137277A/ja
Priority to US14/456,066 priority patent/US20150203466A1/en
Priority to MYPI2014702242A priority patent/MY182857A/en
Publication of TW201529564A publication Critical patent/TW201529564A/zh
Priority to JP2016095437A priority patent/JP6326086B2/ja
Priority to US15/228,202 priority patent/US10285972B2/en
Application granted granted Critical
Publication of TWI553000B publication Critical patent/TWI553000B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW103102539A 2014-01-23 2014-01-23 反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法 TWI553000B (zh)

Priority Applications (8)

Application Number Priority Date Filing Date Title
TW103102539A TWI553000B (zh) 2014-01-23 2014-01-23 反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法
CN201410099171.4A CN104803966A (zh) 2014-01-23 2014-03-17 反式-2-19烷基-4-羟甲基-1,3-二氧戊环化合物及其制备方法
KR1020140036865A KR101644450B1 (ko) 2014-01-23 2014-03-28 트랜스-２-노나데실-４-히드록시메틸-1,3-다이옥살란 화합물 및 그 제조방법
JP2014085186A JP2015137277A (ja) 2014-01-23 2014-04-17 トランス−２−ノナデシル−４−ヒドロキシメチル−１、３−ジオキソラン化合物とその調製方法
US14/456,066 US20150203466A1 (en) 2014-01-23 2014-08-11 Trans-2-nonadecyl-4-hydroxymethyl-1,3-dioxolane and method for producing thereof
MYPI2014702242A MY182857A (en) 2014-01-23 2014-08-12 Trans-2-Nonadecyl-4-Hydroxymethyl-1,3-Dioxolane Compound and Preparation Method Thereof
JP2016095437A JP6326086B2 (ja) 2014-01-23 2016-05-11 トランス−２−ノナデシル−４−ヒドロキシメチル−１、３−ジオキソラン化合物とその調製方法
US15/228,202 US10285972B2 (en) 2014-01-23 2016-08-04 Trans-2-nonadecyl-4-hydroxymethyl-1,3-dioxolane and producing methodthereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW103102539A TWI553000B (zh) 2014-01-23 2014-01-23 反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法

Publications (2)

Publication Number Publication Date
TW201529564A TW201529564A (zh) 2015-08-01
TWI553000B true TWI553000B (zh) 2016-10-11

Family

ID=53544198

Family Applications (1)

Application Number Title Priority Date Filing Date
TW103102539A TWI553000B (zh) 2014-01-23 2014-01-23 反式－２－１９烷基－４－羥甲基－１，３－二氧戊環化合物及其製備方法

Country Status (6)

Country Link
US (1) US20150203466A1 (https=)
JP (2) JP2015137277A (https=)
KR (1) KR101644450B1 (https=)
CN (1) CN104803966A (https=)
MY (1) MY182857A (https=)
TW (1) TWI553000B (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2906807A1 (fr) * 2006-10-09 2008-04-11 Arkema France Procede de synthese d'acetals cycliques par extraction reactive d'un polyol en solution concentree
FR2950894B1 (fr) * 2009-10-06 2011-12-23 Arkema France Utilisation d'acetals de glycerol comme agents de coalescence pour laques, peintures ou vernis et compositions les comprenant
TW201114465A (en) * 2009-10-19 2011-05-01 Univ Nat Kaohsiung Marine Purification process and substance for clam

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
蔡晨瑜，台灣養殖蜆有效成分抑制二甲基亞胺誘發轉型生長因子-beta1表現之保健功效，國立高雄海洋科技大學，2009 *

Also Published As

Publication number Publication date
MY182857A (en) 2021-02-05
US20150203466A1 (en) 2015-07-23
KR101644450B1 (ko) 2016-08-10
TW201529564A (zh) 2015-08-01
CN104803966A (zh) 2015-07-29
JP6326086B2 (ja) 2018-05-16
JP2015137277A (ja) 2015-07-30
KR20150088162A (ko) 2015-07-31
JP2016138150A (ja) 2016-08-04

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