TWI512783B - 可攜式質譜儀裝置及方法 - Google Patents

可攜式質譜儀裝置及方法 Download PDF

Info

Publication number
TWI512783B
TWI512783B TW099145494A TW99145494A TWI512783B TW I512783 B TWI512783 B TW I512783B TW 099145494 A TW099145494 A TW 099145494A TW 99145494 A TW99145494 A TW 99145494A TW I512783 B TWI512783 B TW I512783B
Authority
TW
Taiwan
Prior art keywords
analyte
equal
source
mass
ratio
Prior art date
Application number
TW099145494A
Other languages
English (en)
Chinese (zh)
Other versions
TW201135794A (en
Inventor
Chung Hsuan Chen
Jung Lee Lin
Ming Lee Chu
Original Assignee
Academia Sinica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academia Sinica filed Critical Academia Sinica
Publication of TW201135794A publication Critical patent/TW201135794A/zh
Application granted granted Critical
Publication of TWI512783B publication Critical patent/TWI512783B/zh

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0022Portable spectrometers, e.g. devices comprising independent power supply, constructional details relating to portability
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods
    • H01J49/429Scanning an electric parameter, e.g. voltage amplitude or frequency
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/424Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
TW099145494A 2009-12-23 2010-12-23 可攜式質譜儀裝置及方法 TWI512783B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28953109P 2009-12-23 2009-12-23

Publications (2)

Publication Number Publication Date
TW201135794A TW201135794A (en) 2011-10-16
TWI512783B true TWI512783B (zh) 2015-12-11

Family

ID=44149732

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099145494A TWI512783B (zh) 2009-12-23 2010-12-23 可攜式質譜儀裝置及方法

Country Status (5)

Country Link
US (1) US9224586B2 (enExample)
EP (1) EP2517223A4 (enExample)
JP (1) JP5890782B2 (enExample)
TW (1) TWI512783B (enExample)
WO (1) WO2011079202A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8669521B2 (en) * 2010-09-24 2014-03-11 Wisconsin Alumni Research Foundation Microwave cavity detector for mass spectrometry
JP2014526046A (ja) * 2011-08-05 2014-10-02 アカデミア シニカ 高速プロテオミクスのためのステップ走査式イオントラップ質量分析
DE102012008972B4 (de) * 2012-05-03 2018-02-01 Bruker Daltonik Gmbh Spannungsquellen für Massenspektrometer
US9093253B2 (en) * 2012-12-31 2015-07-28 908 Devices Inc. High pressure mass spectrometry systems and methods
US9099286B2 (en) * 2012-12-31 2015-08-04 908 Devices Inc. Compact mass spectrometer
CN111243938B (zh) * 2012-12-31 2023-06-23 九零八图案公司 质谱仪和使用质谱仪测量关于样品的信息的方法
US8878127B2 (en) * 2013-03-15 2014-11-04 The University Of North Carolina Of Chapel Hill Miniature charged particle trap with elongated trapping region for mass spectrometry
US9006650B2 (en) * 2013-05-10 2015-04-14 Academia Sinica Direct measurements of nanoparticles and virus by virus mass spectrometry
RU2533383C1 (ru) * 2013-06-06 2014-11-20 Вячеслав Иванович Козловский Способ разделения заряженных частиц по удельному заряду
US9711341B2 (en) 2014-06-10 2017-07-18 The University Of North Carolina At Chapel Hill Mass spectrometry systems with convective flow of buffer gas for enhanced signals and related methods
US10262850B2 (en) * 2016-12-19 2019-04-16 Perkinelmer Health Sciences Canada, Inc. Inorganic and organic mass spectrometry systems and methods of using them
WO2018138814A1 (ja) * 2017-01-25 2018-08-02 株式会社島津製作所 飛行時間型質量分析装置
JP2017201635A (ja) * 2017-07-20 2017-11-09 908 デバイセズ インク.908 Devices Inc. コンパクトな質量分析計
US10242857B2 (en) 2017-08-31 2019-03-26 The University Of North Carolina At Chapel Hill Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
GB201802917D0 (en) 2018-02-22 2018-04-11 Micromass Ltd Charge detection mass spectrometry
JP7215121B2 (ja) * 2018-12-05 2023-01-31 株式会社島津製作所 イオントラップ質量分析装置
JP2019091700A (ja) * 2019-01-04 2019-06-13 908 デバイセズ インク.908 Devices Inc. コンパクトな質量分析計
US12315696B2 (en) * 2020-03-02 2025-05-27 National Institute For Materials Science Device for observing permeation and diffusion path of observation target gas, observation target gas measuring method, point-defect location detecting device, point-defect location detecting method, and observation samples
US11842891B2 (en) 2020-04-09 2023-12-12 Waters Technologies Corporation Ion detector
JP7141432B2 (ja) * 2020-09-24 2022-09-22 908 デバイセズ インク. コンパクトな質量分析計
WO2023111707A1 (en) 2021-12-15 2023-06-22 Waters Technologies Corporation An inductive detector with integrated amplifier

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5572022A (en) * 1995-03-03 1996-11-05 Finnigan Corporation Method and apparatus of increasing dynamic range and sensitivity of a mass spectrometer
US6262638B1 (en) * 1998-09-28 2001-07-17 Axcelis Technologies, Inc. Tunable and matchable resonator coil assembly for ion implanter linear accelerator
US20050153341A1 (en) * 2003-12-08 2005-07-14 Alexander James N.Iv Apparatus for determining molecular weight
TW200729274A (en) * 2006-01-27 2007-08-01 Univ Nat Sun Yat Sen Electrospray-assisted laser desorption ionization devices, mass spectrometers, and methods for mass spectrometry
US20070272852A1 (en) * 2006-01-26 2007-11-29 Sionex Corporation Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems
US7329866B2 (en) * 2003-01-31 2008-02-12 Yang Wang Two-dimensional ion trap mass spectrometry
US20080149821A1 (en) * 2006-12-21 2008-06-26 Senko Michael W Method and apparatus for identifying the apex of a chromatographic peak

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591969A (en) 1995-04-12 1997-01-07 The United States Of America As Represented By The Secretary Of The Navy Inductive detector for time-of-flight mass spectrometers
JPH09320516A (ja) 1996-05-29 1997-12-12 Shimadzu Corp 四重極質量分析計
US6777671B2 (en) * 2001-04-10 2004-08-17 Science & Engineering Services, Inc. Time-of-flight/ion trap mass spectrometer, a method, and a computer program product to use the same
CA2448332C (en) * 2001-05-25 2009-04-14 Analytica Of Branford, Inc. Multiple detection systems
US6646256B2 (en) 2001-12-18 2003-11-11 Agilent Technologies, Inc. Atmospheric pressure photoionization source in mass spectrometry
US6777673B2 (en) 2001-12-28 2004-08-17 Academia Sinica Ion trap mass spectrometer
JP3840417B2 (ja) * 2002-02-20 2006-11-01 株式会社日立ハイテクノロジーズ 質量分析装置
CA2800040C (en) 2002-10-29 2015-12-29 Target Discovery, Inc. Method for increasing ionization efficiency in mass spectroscopy
US6906320B2 (en) 2003-04-02 2005-06-14 Merck & Co., Inc. Mass spectrometry data analysis techniques
JP4972405B2 (ja) * 2003-06-27 2012-07-11 ブリガム・ヤング・ユニバーシティ 仮想イオントラップ
US7161147B1 (en) 2005-05-20 2007-01-09 Academia Sinica Biological whole cell mass spectrometer
US7838820B2 (en) * 2005-06-06 2010-11-23 UT-Battlelle, LLC Controlled kinetic energy ion source for miniature ion trap and related spectroscopy system and method
US20070027848A1 (en) * 2005-07-29 2007-02-01 Microsoft Corporation Smart search for accessing options
US7645987B2 (en) 2005-09-22 2010-01-12 Academia Sinica Acoustic desorption mass spectrometry
GB0522327D0 (en) * 2005-11-01 2005-12-07 Micromass Ltd Mass spectrometer
US7649170B2 (en) 2006-10-03 2010-01-19 Academia Sinica Dual-polarity mass spectrometer
US8173961B2 (en) * 2007-04-09 2012-05-08 Shimadzu Corporation Ion trap mass spectrometer
US8022363B2 (en) 2007-04-12 2011-09-20 Shimadzu Corporation Ion trap mass spectrometer
US20100320377A1 (en) * 2007-11-09 2010-12-23 The Johns Hopkins University Low voltage, high mass range ion trap spectrometer and analyzing methods using such a device
JP5477295B2 (ja) 2007-12-13 2014-04-23 アカデミア シニカ 電荷監視質量分析を行うためのシステムおよび方法
WO2009095948A1 (ja) * 2008-01-28 2009-08-06 Shimadzu Corporation イオントラップ質量分析装置
US20090189059A1 (en) 2008-01-29 2009-07-30 Smith Darrell I Systems and methods for cross-over bond-wires for tia input
JP4941402B2 (ja) 2008-05-12 2012-05-30 株式会社島津製作所 質量分析装置
US8309912B2 (en) * 2008-11-21 2012-11-13 Applied Nanotech Holdings, Inc. Atmospheric pressure ion trap
US8138472B2 (en) 2009-04-29 2012-03-20 Academia Sinica Molecular ion accelerator
US8153964B2 (en) 2009-05-29 2012-04-10 Academia Sinica Ultrasound ionization mass spectrometer
JP2014526046A (ja) * 2011-08-05 2014-10-02 アカデミア シニカ 高速プロテオミクスのためのステップ走査式イオントラップ質量分析

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5572022A (en) * 1995-03-03 1996-11-05 Finnigan Corporation Method and apparatus of increasing dynamic range and sensitivity of a mass spectrometer
US6262638B1 (en) * 1998-09-28 2001-07-17 Axcelis Technologies, Inc. Tunable and matchable resonator coil assembly for ion implanter linear accelerator
US7329866B2 (en) * 2003-01-31 2008-02-12 Yang Wang Two-dimensional ion trap mass spectrometry
US20050153341A1 (en) * 2003-12-08 2005-07-14 Alexander James N.Iv Apparatus for determining molecular weight
US20070272852A1 (en) * 2006-01-26 2007-11-29 Sionex Corporation Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems
TW200729274A (en) * 2006-01-27 2007-08-01 Univ Nat Sun Yat Sen Electrospray-assisted laser desorption ionization devices, mass spectrometers, and methods for mass spectrometry
US20080149821A1 (en) * 2006-12-21 2008-06-26 Senko Michael W Method and apparatus for identifying the apex of a chromatographic peak

Also Published As

Publication number Publication date
US20110147581A1 (en) 2011-06-23
CN102754181A (zh) 2012-10-24
JP2013516036A (ja) 2013-05-09
EP2517223A1 (en) 2012-10-31
TW201135794A (en) 2011-10-16
WO2011079202A1 (en) 2011-06-30
JP5890782B2 (ja) 2016-03-22
EP2517223A4 (en) 2015-11-18
US9224586B2 (en) 2015-12-29

Similar Documents

Publication Publication Date Title
TWI512783B (zh) 可攜式質譜儀裝置及方法
US10755915B2 (en) Microscale mass spectrometry systems, devices and related methods
JP6588118B2 (ja) イオン生成と、不連続の大気インターフェースの周期との同期
Gao et al. Design and characterization of a multisource hand-held tandem mass spectrometer
US20070272852A1 (en) Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems
US8173959B1 (en) Real-time trace detection by high field and low field ion mobility and mass spectrometry
EP2676286B1 (en) System for mass spectrometry
US10867781B2 (en) Electrospray ionization interface to high pressure mass spectrometry and related methods
US20090078865A1 (en) Apparatus and systems for processing samples for analysis via ion mobility spectrometry
US20110168881A1 (en) Plasma-based direct sampling of molecules for mass spectrometric analysis
Smith et al. Portable instrumentation for ambient ionization and miniature mass spectrometers
Szyszka et al. MEMS quadrupole mass spectrometer
EP1418611A1 (en) Chemical agent detection apparatus and method
Schilling et al. Detection of positive and negative ions from a flowing atmospheric pressure afterglow using a Mattauch-Herzog mass spectrograph equipped with a Faraday-strip array detector
Cooks et al. Through a glass darkly: glimpses into the future of mass spectrometry
Liu et al. Improving the performance of the mini 2000 mass spectrometer with a triboelectric nanogenerator electrospray ionization source
US12261032B2 (en) Low-power mass interrogation system and assay for determining vitamin D levels
CN102754181B (zh) 用于便携式质谱分析的设备和方法
Grimes Applications in Opioid Analysis with FAIMS Through Control of Vapor Phase Solvent Modifiers
CN119560366A (zh) 一种大气挥发性有机污染物溯源无人机离子阱质谱系统及其应用方法
Stindt Probing levitated droplets with mass spectrometry