TWI481870B - 用於軟組織疾病診斷及作為用於口腔保健干預的標靶之蛋白質生物標記 - Google Patents
用於軟組織疾病診斷及作為用於口腔保健干預的標靶之蛋白質生物標記 Download PDFInfo
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- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical compound OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 description 1
- 229950000975 salicylanilide Drugs 0.000 description 1
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- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 description 1
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- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
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Classifications
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56955—Bacteria involved in periodontal diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
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|---|---|---|---|
| US16567409P | 2009-04-01 | 2009-04-01 |
Publications (2)
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| TW201102653A TW201102653A (en) | 2011-01-16 |
| TWI481870B true TWI481870B (zh) | 2015-04-21 |
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| EP (1) | EP2414837B1 (enExample) |
| JP (1) | JP5643288B2 (enExample) |
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| BR (1) | BRPI1013184A2 (enExample) |
| CA (1) | CA2753718C (enExample) |
| CO (1) | CO6430490A2 (enExample) |
| MX (1) | MX2011008439A (enExample) |
| MY (1) | MY179250A (enExample) |
| RU (1) | RU2523383C2 (enExample) |
| SG (1) | SG173461A1 (enExample) |
| TW (1) | TWI481870B (enExample) |
| WO (1) | WO2010115034A2 (enExample) |
| ZA (1) | ZA201106056B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI405565B (zh) * | 2009-04-01 | 2013-08-21 | Colgate Palmolive Co | 口腔用組成物之抗－骨質流失及抗－牙周附連喪失之功效 |
| US9949671B2 (en) | 2013-03-13 | 2018-04-24 | Orthoaccel Technologies, Inc. | Diagnostic mouthpieces |
| WO2018129043A1 (en) * | 2017-01-03 | 2018-07-12 | The Trustees Of The University Of Pennsylvania | Compositions and methods for predicting risk of preterm birth |
| JP7486316B2 (ja) | 2017-05-24 | 2024-05-17 | コーニンクレッカ フィリップス エヌ ヴェ | 唾液のｉｌ－１ベータ及びｍｍｐ－９に基づく軽度の又は進行した歯周炎の診断 |
| EP3631458A1 (en) * | 2017-05-24 | 2020-04-08 | Koninklijke Philips N.V. | Diagnostics of periodontitis based on salivary hgf and mmp-8 |
| WO2018215596A1 (en) * | 2017-05-24 | 2018-11-29 | Koninklijke Philips N.V. | Diagnostics of gingivitis based on salivary il-1beta and hgf |
| WO2019084351A1 (en) | 2017-10-27 | 2019-05-02 | The Regents Of The University Of California | SALIVARY EXTRACELLULAR RNA BIOMARKERS FOR GINGIVITIS |
| EP3477306A1 (en) * | 2017-10-30 | 2019-05-01 | Koninklijke Philips N.V. | Classification of periodontitis patients |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US4358437A (en) | 1978-11-29 | 1982-11-09 | Beecham Group Limited | Compositions |
| US5288480A (en) | 1987-01-30 | 1994-02-22 | Colgate-Palmolive Co. | Antiplaque antibacterial oral composition |
| GB9117140D0 (en) | 1991-08-08 | 1991-09-25 | Unilever Plc | Treatment of periodontitis |
| DE4226043A1 (de) | 1992-08-06 | 1994-02-10 | Haarmann & Reimer Gmbh | Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen |
| CA2176237A1 (en) | 1993-11-10 | 1995-05-18 | Richard P. Darveau | Treatment of bacterially-induced inflammatory diseases |
| US5578295A (en) | 1995-04-28 | 1996-11-26 | The Procter & Gamble Company | Oral care compositions comprising certain substituted diphenyl ethers |
| EP0935454B1 (de) | 1996-06-12 | 2001-08-22 | Cognis Deutschland GmbH | Kosmetische und/oder pharmazeutische zubereitungen |
| FR2794457B1 (fr) | 1999-06-01 | 2001-08-10 | Oreal | Derives carbonates de retinol, procede de preparation et utilisations |
| WO2001048481A1 (en) | 1999-12-03 | 2001-07-05 | Baxter International Inc. | Pyrogenicity test for use with automated immunoassay systems |
| GB0001704D0 (en) | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Protein |
| WO2001078652A2 (en) | 2000-04-14 | 2001-10-25 | Metabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US6500409B1 (en) | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
| DE10059584A1 (de) | 2000-11-30 | 2002-06-06 | Beiersdorf Ag | Kosmetische oder dermatologische getränkte Tücher |
| US7005225B2 (en) | 2002-11-12 | 2006-02-28 | Samsung Electronics Company | Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications |
| TW200902047A (en) | 2003-02-14 | 2009-01-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| GB2401865A (en) | 2003-05-22 | 2004-11-24 | Givaudan Sa | Antibacterial and antifungal glycerol monocarbonates |
| WO2005039504A2 (en) | 2003-10-24 | 2005-05-06 | Eisai Co., Ltd. | Compounds and methods for treating toll-like receptor 2-related diseases and conditions |
| US20070212686A1 (en) | 2003-12-03 | 2007-09-13 | Whitehead Institute For Biomedical Research | Use Of T-Cadherin As A Target |
| FI20040572A0 (fi) * | 2004-04-23 | 2004-04-23 | Ctt Cancer Targeting Tech Oy | Matriisi-metalloproteinaasin aktiviteetin inhibiittorit |
| US20050271601A1 (en) * | 2004-06-02 | 2005-12-08 | Nebojsa Milanovich | Anti-staining antibacterial dentifrice |
| WO2006068133A1 (ja) * | 2004-12-21 | 2006-06-29 | National University Corporation NARA Institute of Science and Technology | Ｎｆａｔ２発現抑制方法 |
| US20060141421A1 (en) | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | System and method for detecting substances related to oral health |
| WO2006074450A2 (en) | 2005-01-07 | 2006-07-13 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases |
| RU2431845C2 (ru) * | 2006-01-10 | 2011-10-20 | Колгейт-Палмолив Компани | Способы модулирования рецепторов клеточных поверхностей для предотвращения или снижения воспаления |
| US20080161394A1 (en) | 2006-11-23 | 2008-07-03 | Jean-Yves Fouron | Cosmetic composition comprising at least one volatile carbonic acid ester |
| WO2008093072A2 (en) | 2007-01-29 | 2008-08-07 | Paul Webb | Topical composition against contact dermatitis due to water |
| US8333981B2 (en) | 2007-10-09 | 2012-12-18 | Humco Holding Group, Inc. | Antifungal treatment of nails |
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2010
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- 2010-03-31 AR ARP100101093A patent/AR076041A1/es unknown
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2011
- 2011-08-17 ZA ZA2011/06056A patent/ZA201106056B/en unknown
- 2011-09-27 CO CO11126599A patent/CO6430490A2/es active IP Right Grant
Non-Patent Citations (3)
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|---|
| Yoshioka masami, et al., "Effect of hydroxamic acid-based matrix metalloproteinase inhibitors on human gingival cells and porphyromonas gingivalis", Journal of periodontology, Vol. 74, No. 8, 1219-1224, 2003. * |
| Young Joon Kim, et al., "Prostaglandin Production by Human Gingival Fibroblasts Inhibited by Triclosan in the Presence of Cetylpyridinium Chloride" Journal of periodontology, Vol. 76, No. 10, 1735-1742, 2005. * |
| 秦念紅等，"鹽酸米諾四環素軟膏對齦溝液中白細胞介素-8的影響"，武漢大學學報(醫學版)，第27卷，第1期，2006年 * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2523383C2 (ru) | 2014-07-20 |
| CO6430490A2 (es) | 2012-04-30 |
| CN102549432B (zh) | 2015-03-25 |
| WO2010115034A2 (en) | 2010-10-07 |
| US20120028261A1 (en) | 2012-02-02 |
| CN102549432A (zh) | 2012-07-04 |
| BRPI1013184A2 (pt) | 2016-04-12 |
| AR076041A1 (es) | 2011-05-11 |
| EP2414837A2 (en) | 2012-02-08 |
| ZA201106056B (en) | 2015-05-27 |
| US8753820B2 (en) | 2014-06-17 |
| AU2010232593A1 (en) | 2011-08-25 |
| TW201102653A (en) | 2011-01-16 |
| MY179250A (en) | 2020-11-02 |
| SG173461A1 (en) | 2011-09-29 |
| WO2010115034A3 (en) | 2010-12-29 |
| JP2012522994A (ja) | 2012-09-27 |
| JP5643288B2 (ja) | 2014-12-17 |
| EP2414837B1 (en) | 2015-06-03 |
| RU2011144032A (ru) | 2013-05-10 |
| MX2011008439A (es) | 2011-09-06 |
| CA2753718C (en) | 2015-06-23 |
| CA2753718A1 (en) | 2010-10-07 |
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