TWI448290B - 與健擇他濱（ｇｅｍｃｉｔａｂｉｎｅ）組合用於胰臟癌之治療的中等鏈長脂肪酸、鹽類及三酸甘油酯 - Google Patents
與健擇他濱（ｇｅｍｃｉｔａｂｉｎｅ）組合用於胰臟癌之治療的中等鏈長脂肪酸、鹽類及三酸甘油酯 Download PDFInfo
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- TWI448290B TWI448290B TW097149396A TW97149396A TWI448290B TW I448290 B TWI448290 B TW I448290B TW 097149396 A TW097149396 A TW 097149396A TW 97149396 A TW97149396 A TW 97149396A TW I448290 B TWI448290 B TW I448290B
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- A—HUMAN NECESSITIES
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Landscapes
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| ES2575100T3 (es) | 2009-05-04 | 2016-06-24 | Prometic Pharma Smt Limited | Compuestos aromáticos sustituidos y usos farmacéuticos de los mismos |
| EA030038B1 (ru) | 2010-10-27 | 2018-06-29 | Прометик Фарма Смт Лимитед | Применение соединений для лечения рака и способ лечения рака |
| CN102617679B (zh) * | 2012-03-13 | 2014-11-26 | 北京大学 | 一种共轭亚油酸与吉西他滨连接的前体药物制备方法及其应用 |
| JP6396333B2 (ja) | 2013-02-12 | 2018-09-26 | ベンド・リサーチ・インコーポレーテッドＢｅｎｄ Ｒｅｓｅａｒｃｈ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 低水溶性活性物質の固体分散体 |
| US9737538B2 (en) | 2013-02-12 | 2017-08-22 | Bend Research, Inc. | Solid dispersions of low-water solubility actives |
| KR102213143B1 (ko) * | 2013-02-28 | 2021-02-08 | 바스프 에이에스 | 지방질 화합물, 트리글리세리드 및 계면활성제를 포함하는 조성물 및 이를 이용하는 방법 |
| US10463684B2 (en) | 2014-01-29 | 2019-11-05 | Board Of Regents, The Uneversety Of Texas System | Nucleobase analogue derivatives and their applications |
| CN120923343A (zh) | 2018-10-11 | 2025-11-11 | 巴斯夫股份公司 | 芳族化合物及其医药用途 |
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| WO1990010441A1 (en) * | 1989-03-13 | 1990-09-20 | Thornfeldt Carl R | Treatment of skin diseases and tumors |
| US6340705B1 (en) * | 1999-09-10 | 2002-01-22 | Monsanto Technology, Llc | Use of α-linolenic acid metabolites for treatment or prevention of cancer |
| EP1900364B1 (en) | 2001-04-18 | 2013-09-25 | ProMetic BioSciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| CA2457526A1 (en) * | 2001-08-29 | 2003-03-13 | Umd, Inc. | Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy |
| US20060012880A1 (en) * | 2002-05-02 | 2006-01-19 | Law Benjamin P | Optical device with refractive and diffractive properties |
| CN100427081C (zh) * | 2003-02-07 | 2008-10-22 | 普罗米蒂克生物科学公司 | 作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物 |
| ES2264886B1 (es) * | 2005-05-12 | 2008-02-01 | Proyecto Empresarial Brudy, S.L. | Utilizacion de acido docosahexaenoico para el tratamiento de enfermedades tumorales. |
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| ES2414617T3 (es) | 2013-07-22 |
| CA2708679C (en) | 2016-11-15 |
| CN101903028B (zh) | 2013-06-05 |
| JP5473937B2 (ja) | 2014-04-16 |
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| JP2011506492A (ja) | 2011-03-03 |
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| TW200934494A (en) | 2009-08-16 |
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| WO2009076761A1 (en) | 2009-06-25 |
| NZ586249A (en) | 2012-05-25 |
| MX2010006867A (es) | 2010-08-31 |
| CN101903028A (zh) | 2010-12-01 |
| HK1151244A1 (en) | 2012-01-27 |
| CA2708679A1 (en) | 2009-06-25 |
| US20100273731A1 (en) | 2010-10-28 |
| PT2231166E (pt) | 2013-06-17 |
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