TWI434853B - 腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗 - Google Patents
腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Cell Biology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
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| US91119407P | 2007-04-11 | 2007-04-11 |
Publications (2)
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| TW200906850A TW200906850A (en) | 2009-02-16 |
| TWI434853B true TWI434853B (zh) | 2014-04-21 |
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| TW103110837A TW201425333A (zh) | 2007-04-11 | 2008-04-08 | 腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗 |
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| US (1) | US8367799B2 (OSRAM) |
| EP (2) | EP2508601B1 (OSRAM) |
| JP (1) | JP5320544B2 (OSRAM) |
| KR (1) | KR20100016355A (OSRAM) |
| CN (2) | CN101711280B (OSRAM) |
| BR (1) | BRPI0811021A2 (OSRAM) |
| CA (1) | CA2683454A1 (OSRAM) |
| IL (2) | IL201386A0 (OSRAM) |
| MX (1) | MX2009010965A (OSRAM) |
| RU (2) | RU2498993C2 (OSRAM) |
| TW (2) | TWI434853B (OSRAM) |
| WO (1) | WO2008126413A1 (OSRAM) |
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| TWI539160B (zh) * | 2008-12-05 | 2016-06-21 | 腫瘤療法 科學股份有限公司 | Ｗｄｒｐｕｈ抗原決定位胜肽以及含此胜肽之疫苗 |
| US8574902B2 (en) * | 2009-03-05 | 2013-11-05 | Macrocure Ltd. | Activated leukocyte composition and uses for wound healing |
| TW201136604A (en) | 2009-12-14 | 2011-11-01 | Oncotherapy Science Inc | TMEM22 peptides and vaccines including the same |
| JP5838482B2 (ja) * | 2010-03-11 | 2016-01-06 | オンコセラピー・サイエンス株式会社 | Ｈｊｕｒｐペプチドおよびそれを含むワクチン |
| JP2013523084A (ja) * | 2010-04-09 | 2013-06-17 | オンコセラピー・サイエンス株式会社 | Ｃｄｃａ５ペプチドおよびそれを含むワクチン |
| US8557777B2 (en) * | 2010-07-09 | 2013-10-15 | The Board Of Trustees Of The University Of Illinois | Methods for treating cancer using prostate specific antigen and tumor endothelial marker peptides |
| CN103209682A (zh) | 2010-09-09 | 2013-07-17 | 马克罗柯尔有限公司 | 活化白血球调节上清液以及用于伤口愈合的用途 |
| UA110119C2 (xx) * | 2010-12-02 | 2015-11-25 | Пептиди tomm34 та вакцини, що їх містять | |
| MX350220B (es) * | 2011-08-12 | 2017-08-30 | Oncotherapy Science Inc | Peptidos de mphosph1 y vacunas que incluyen los mismos. |
| UA114298C2 (uk) * | 2011-10-28 | 2017-05-25 | Онкотерапі Саєнс, Інк. | Пептид торк та вакцина, що його містить |
| JP2016502499A (ja) * | 2012-12-04 | 2016-01-28 | オンコセラピー・サイエンス株式会社 | Ｓｅｍａ５ｂペプチドおよびそれを含むワクチン |
| TW201636358A (zh) * | 2014-12-09 | 2016-10-16 | 腫瘤療法 科學股份有限公司 | 對於ｔｈ１細胞之ｇｐｃ３抗原決定位胜肽及含此之疫苗 |
| CN106084026B (zh) * | 2016-06-19 | 2019-10-25 | 中国人民解放军军事医学科学院生物工程研究所 | 肿瘤血管内皮细胞标志物8突变体、其融合蛋白及应用 |
| RU2706554C1 (ru) * | 2018-12-13 | 2019-11-19 | Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ | Способ создания противоинфекционной иммунологической защиты к Salmonella typhimurium и Listeria monocytogenes с помощью трансгенеза Т-лимфоцитов |
| KR102873723B1 (ko) * | 2025-03-26 | 2025-10-22 | 주식회사 포트래이 | Antxr1 결합 항체 및 이의 용도 |
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| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
| AU6632496A (en) | 1995-08-03 | 1997-03-05 | Rijksuniversiteit Te Leiden | Cell derived antigen presenting vesicles |
| US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
| JP2000516090A (ja) | 1996-07-26 | 2000-12-05 | スローン―ケッタリング インスティチュート フォー キャンサー リサーチ | 遺伝子的免疫化のための方法と試薬 |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| US6426205B1 (en) * | 1997-10-24 | 2002-07-30 | Mount Sinai Hospital Corporation | Methods and compositions for modulating ubiquitin dependent proteolysis |
| ATE375362T1 (de) | 1998-06-25 | 2007-10-15 | Kyogo Itoh | Von cyclophilin b abstammende tumorantigen- peptide |
| US6465717B1 (en) * | 1998-11-20 | 2002-10-15 | E. I. Du Pont De Nemours And Company | Sterol metabolism enzymes |
| AU2486300A (en) * | 1998-12-30 | 2000-07-31 | Millennium Pharmaceuticals, Inc. | Secreted proteins and nucleic acids encoding them |
| AU2001283062A1 (en) * | 2000-08-02 | 2002-02-13 | The Johns Hopkins University | Endothelial cell expression patterns |
| DE60128008T2 (de) * | 2000-12-05 | 2008-01-10 | Wisconsin Alumni Research Foundation, Madison | Rezeptor für ein toxin aus bacillus anthracis |
| US20030092616A1 (en) * | 2001-05-25 | 2003-05-15 | Akio Matsuda | STAT6 activation gene |
| US6936707B2 (en) * | 2001-07-11 | 2005-08-30 | Zeon Corporation | Modified DNA molecule, recombinant containing the same, and uses thereof |
| US7112717B2 (en) * | 2002-03-19 | 2006-09-26 | Monsanto Technology Llc | Homogentisate prenyl transferase gene (HPT2) from arabidopsis and uses thereof |
| US7160994B2 (en) * | 2002-03-28 | 2007-01-09 | Trustees Of The University Of Pennsylvania | Osteoclast-specific genes and proteins and uses thereof |
| EP1548032B9 (en) * | 2002-09-12 | 2009-10-28 | Oncotherapy Science, Inc. | Kdr peptides and vaccines comprising the same |
| JP2007511534A (ja) | 2003-11-13 | 2007-05-10 | スローン−ケッタリング インスティトゥート フォー カンサー リサーチ | 抗腫瘍免疫の相乗的誘導のための組成物および方法 |
| JP4628208B2 (ja) * | 2004-08-10 | 2011-02-09 | オンコセラピー・サイエンス株式会社 | Ｃｘａｄｒｌ１またはｇｃｕｄ１タンパク質を発現する胃癌または結腸直腸癌の治療のためのペプチドワクチン |
| CA2580412A1 (en) | 2004-09-13 | 2006-03-23 | Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services | Compositions comprising t cell receptors and methods of use thereof |
| KR101130597B1 (ko) | 2005-09-13 | 2012-04-02 | 다카라 바이오 가부시키가이샤 | Ｔ 세포 리셉터 및 그 리셉터를 코드하는 핵산 |
| ITRM20060337A1 (it) * | 2006-06-27 | 2007-12-28 | Biosoot Srl | Gene tem8 (tumor endotelial marker 8) e sue forme di espressione ed usi diagnostici e terapeutici |
-
2008
- 2008-04-08 TW TW097112625A patent/TWI434853B/zh not_active IP Right Cessation
- 2008-04-08 TW TW103110837A patent/TW201425333A/zh unknown
- 2008-04-10 EP EP12166766.1A patent/EP2508601B1/en not_active Not-in-force
- 2008-04-10 JP JP2009536553A patent/JP5320544B2/ja not_active Expired - Fee Related
- 2008-04-10 CN CN2008800199287A patent/CN101711280B/zh not_active Expired - Fee Related
- 2008-04-10 WO PCT/JP2008/000932 patent/WO2008126413A1/en not_active Ceased
- 2008-04-10 CN CN201210286846.7A patent/CN102786582B/zh not_active Expired - Fee Related
- 2008-04-10 CA CA002683454A patent/CA2683454A1/en not_active Abandoned
- 2008-04-10 BR BRPI0811021-2A2A patent/BRPI0811021A2/pt not_active IP Right Cessation
- 2008-04-10 KR KR1020097023352A patent/KR20100016355A/ko not_active Abandoned
- 2008-04-10 MX MX2009010965A patent/MX2009010965A/es active IP Right Grant
- 2008-04-10 RU RU2009141595/10A patent/RU2498993C2/ru not_active IP Right Cessation
- 2008-04-10 EP EP08738544A patent/EP2155872A4/en not_active Withdrawn
- 2008-04-10 US US12/595,197 patent/US8367799B2/en not_active Expired - Fee Related
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2009
- 2009-10-11 IL IL201386A patent/IL201386A0/en unknown
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2012
- 2012-07-04 IL IL220752A patent/IL220752A0/en unknown
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- 2013-07-05 RU RU2013131089/10A patent/RU2013131089A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010523471A (ja) | 2010-07-15 |
| TW201425333A (zh) | 2014-07-01 |
| EP2508601A2 (en) | 2012-10-10 |
| WO2008126413A1 (en) | 2008-10-23 |
| TW200906850A (en) | 2009-02-16 |
| IL220752A0 (en) | 2012-08-30 |
| CA2683454A1 (en) | 2008-10-23 |
| EP2155872A4 (en) | 2010-04-28 |
| BRPI0811021A2 (pt) | 2014-10-21 |
| RU2498993C2 (ru) | 2013-11-20 |
| EP2155872A1 (en) | 2010-02-24 |
| HK1175197A1 (en) | 2013-06-28 |
| JP5320544B2 (ja) | 2013-10-23 |
| MX2009010965A (es) | 2009-12-01 |
| US8367799B2 (en) | 2013-02-05 |
| IL201386A0 (en) | 2011-08-01 |
| RU2013131089A (ru) | 2015-01-10 |
| RU2009141595A (ru) | 2011-05-20 |
| AU2008238739A1 (en) | 2008-10-23 |
| CN102786582A (zh) | 2012-11-21 |
| CN102786582B (zh) | 2014-06-11 |
| EP2508601A3 (en) | 2013-02-13 |
| US20120093843A1 (en) | 2012-04-19 |
| EP2508601B1 (en) | 2014-11-05 |
| CN101711280A (zh) | 2010-05-19 |
| CN101711280B (zh) | 2013-04-10 |
| KR20100016355A (ko) | 2010-02-12 |
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| MM4A | Annulment or lapse of patent due to non-payment of fees |