TWI343994B - - Google Patents
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- Publication number
- TWI343994B TWI343994B TW094121661A TW94121661A TWI343994B TW I343994 B TWI343994 B TW I343994B TW 094121661 A TW094121661 A TW 094121661A TW 94121661 A TW94121661 A TW 94121661A TW I343994 B TWI343994 B TW I343994B
- Authority
- TW
- Taiwan
- Prior art keywords
- light
- microchip
- sample
- reagent
- detecting portion
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims description 31
- 238000005259 measurement Methods 0.000 claims description 31
- 230000003287 optical effect Effects 0.000 claims description 6
- 239000000872 buffer Substances 0.000 claims description 4
- 238000004458 analytical method Methods 0.000 abstract description 8
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 24
- 238000001514 detection method Methods 0.000 description 19
- 230000000052 comparative effect Effects 0.000 description 16
- 238000002835 absorbance Methods 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- 238000000034 method Methods 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 238000002834 transmittance Methods 0.000 description 8
- 108090000790 Enzymes Proteins 0.000 description 7
- 102000004190 Enzymes Human genes 0.000 description 7
- 239000012535 impurity Substances 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 238000007689 inspection Methods 0.000 description 5
- 108020004206 Gamma-glutamyltransferase Proteins 0.000 description 4
- 238000009825 accumulation Methods 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- 102000006640 gamma-Glutamyltransferase Human genes 0.000 description 4
- KZZWQCKYLNIOBT-UHFFFAOYSA-N 5-amino-2-nitrobenzoic acid Chemical compound NC1=CC=C([N+]([O-])=O)C(C(O)=O)=C1 KZZWQCKYLNIOBT-UHFFFAOYSA-N 0.000 description 3
- -1 aminoglycolylaminoacetic acid Chemical compound 0.000 description 3
- 238000004159 blood analysis Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000000538 analytical sample Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- YMAWOPBAYDPSLA-UHFFFAOYSA-N glycylglycine Chemical compound [NH3+]CC(=O)NCC([O-])=O YMAWOPBAYDPSLA-UHFFFAOYSA-N 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 2
- 229910052724 xenon Inorganic materials 0.000 description 2
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 2
- SLAMLWHELXOEJZ-UHFFFAOYSA-N 2-nitrobenzoic acid Chemical compound OC(=O)C1=CC=CC=C1[N+]([O-])=O SLAMLWHELXOEJZ-UHFFFAOYSA-N 0.000 description 1
- AHFFWTMLFDZSOF-QMMMGPOBSA-N 53602-84-9 Chemical compound OC(=O)[C@@H](N)CCC(=O)NC1=CC=C([N+]([O-])=O)C(C(O)=O)=C1 AHFFWTMLFDZSOF-QMMMGPOBSA-N 0.000 description 1
- 108010008488 Glycylglycine Proteins 0.000 description 1
- NTPHJDOBLLEMRI-UHFFFAOYSA-N NCC(=O)NCC(=O)O.C(C)(=O)NCC(=O)O Chemical compound NCC(=O)NCC(=O)O.C(C)(=O)NCC(=O)O NTPHJDOBLLEMRI-UHFFFAOYSA-N 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 229940043257 glycylglycine Drugs 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- HHRBLMVGQRQPML-UHFFFAOYSA-N hydroxy-bis(sulfanyl)-sulfanylidene-lambda5-arsane Chemical group O[As](S)(S)=S HHRBLMVGQRQPML-UHFFFAOYSA-N 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
- G01N2021/0328—Arrangement of two or more cells having different functions for the measurement of reactions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004274673A JP4375183B2 (ja) | 2004-09-22 | 2004-09-22 | マイクロチップ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200610952A TW200610952A (en) | 2006-04-01 |
| TWI343994B true TWI343994B (enExample) | 2011-06-21 |
Family
ID=35462319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094121661A TW200610952A (en) | 2004-09-22 | 2005-06-28 | Microchip |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7981689B2 (enExample) |
| EP (1) | EP1640703B1 (enExample) |
| JP (1) | JP4375183B2 (enExample) |
| CN (1) | CN100570332C (enExample) |
| DE (1) | DE602005016506D1 (enExample) |
| TW (1) | TW200610952A (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4506375B2 (ja) * | 2004-09-22 | 2010-07-21 | ウシオ電機株式会社 | 吸光度測定ユニット |
| JP4912096B2 (ja) * | 2006-09-07 | 2012-04-04 | ローム株式会社 | マイクロチップ検査装置 |
| US20090141282A1 (en) * | 2007-12-04 | 2009-06-04 | Yung-Lieh Chien | Concentration measuring structure capable of reducing the effect of environmental temperature |
| WO2010120786A1 (en) | 2009-04-13 | 2010-10-21 | Micronics, Inc. | Microfluidic clinical analyzer |
| WO2011094577A2 (en) | 2010-01-29 | 2011-08-04 | Micronics, Inc. | Sample-to-answer microfluidic cartridge |
| CN103140755B (zh) | 2010-07-22 | 2016-03-16 | 哈希公司 | 用于碱度分析的芯片上实验室 |
| FR2981283B1 (fr) * | 2011-10-13 | 2014-08-29 | Chambre De Commerce Et De L Ind De Paris Au Titre De Son Etablissement D Enseignement Superieur Esie | Dispositif microfluidique pour analyser un fluide sous pression. |
| US8741234B2 (en) * | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US9180449B2 (en) | 2012-06-12 | 2015-11-10 | Hach Company | Mobile water analysis |
| USD768872S1 (en) | 2012-12-12 | 2016-10-11 | Hach Company | Cuvette for a water analysis instrument |
| JP2016509206A (ja) | 2012-12-21 | 2016-03-24 | マイクロニクス， インコーポレイテッド | 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ |
| WO2014100732A1 (en) | 2012-12-21 | 2014-06-26 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
| US10518262B2 (en) | 2012-12-21 | 2019-12-31 | Perkinelmer Health Sciences, Inc. | Low elasticity films for microfluidic use |
| CN105189784B (zh) | 2013-05-07 | 2020-06-30 | 珀金埃尔默健康科学有限公司 | 用于制备和分析核酸的装置 |
| CA2911303C (en) | 2013-05-07 | 2021-02-16 | Micronics, Inc. | Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions |
| WO2014182844A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
| US10539582B2 (en) | 2014-06-30 | 2020-01-21 | Phc Holdings Corporation | Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles |
| US10520521B2 (en) | 2014-06-30 | 2019-12-31 | Phc Holdings Corporation | Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system |
| WO2016002731A1 (ja) | 2014-06-30 | 2016-01-07 | パナソニックヘルスケアホールディングス株式会社 | 試料分析用基板および試料分析装置 |
| US10309976B2 (en) | 2014-06-30 | 2019-06-04 | Phc Holdings Corporation | Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system |
| WO2016093332A1 (ja) | 2014-12-12 | 2016-06-16 | パナソニックヘルスケアホールディングス株式会社 | 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム |
| KR20180080396A (ko) * | 2017-01-02 | 2018-07-12 | 한국전자통신연구원 | 바이오 센서 |
| WO2022155142A1 (en) * | 2021-01-12 | 2022-07-21 | Repligen Corporation | Offline and inline determination of concentration of metabolites in cell culture fluid |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE399768B (sv) * | 1975-09-29 | 1978-02-27 | Lilja Jan E | Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet |
| US4226531A (en) * | 1977-08-29 | 1980-10-07 | Instrumentation Laboratory Inc. | Disposable multi-cuvette rotor |
| US5798215A (en) * | 1993-02-18 | 1998-08-25 | Biocircuits Corporation | Device for use in analyte detection assays |
| US6046840A (en) * | 1995-06-19 | 2000-04-04 | Reflectivity, Inc. | Double substrate reflective spatial light modulator with self-limiting micro-mechanical elements |
| US6088102A (en) * | 1997-10-31 | 2000-07-11 | Silicon Light Machines | Display apparatus including grating light-valve array and interferometric optical system |
| CA2320296A1 (en) * | 1998-05-18 | 1999-11-25 | University Of Washington | Liquid analysis cartridge |
| US6188519B1 (en) * | 1999-01-05 | 2001-02-13 | Kenneth Carlisle Johnson | Bigrating light valve |
| EP1247248A4 (en) * | 1999-12-14 | 2010-03-03 | Comb Specialists Inc | DETECTION SYSTEM FOR DETECTING AND MONITORING / CONTROLLING DEPOSITION ON SUSPENDED TUBES IN RECOVERY AND POWER GENERATION BOILERS |
| US20030152927A1 (en) * | 2000-10-25 | 2003-08-14 | Jakobsen Mogens Havsteen | Closed substrate platforms suitable for analysis of biomolecules |
| JP3760810B2 (ja) * | 2001-07-06 | 2006-03-29 | ソニー株式会社 | 光変調素子、ｇｌｖデバイス、及びレーザディスプレイ |
| JP2003279471A (ja) | 2002-03-20 | 2003-10-02 | Nippon Sheet Glass Co Ltd | マイクロ化学システム用チップ及びマイクロ化学システム |
| US6768555B2 (en) * | 2002-03-21 | 2004-07-27 | Industrial Technology Research Institute | Fabry-Perot filter apparatus with enhanced optical discrimination |
| JP2004077305A (ja) * | 2002-08-19 | 2004-03-11 | Nec Corp | 検出装置 |
| JP2004109099A (ja) * | 2002-09-16 | 2004-04-08 | Jun Kikuchi | 血液分析方法、血液分析装置および血液分析装置の製造方法 |
| JP4057871B2 (ja) * | 2002-09-19 | 2008-03-05 | 東芝松下ディスプレイテクノロジー株式会社 | 液晶表示装置 |
| US6822780B1 (en) * | 2003-06-23 | 2004-11-23 | Northrop Grumman Corporation | Vertically stacked spatial light modulator with multi-bit phase resolution |
| US7691328B2 (en) * | 2003-10-03 | 2010-04-06 | National Institute For Materials Science | Chip using method and test chip |
| US7710632B2 (en) * | 2004-09-27 | 2010-05-04 | Qualcomm Mems Technologies, Inc. | Display device having an array of spatial light modulators with integrated color filters |
-
2004
- 2004-09-22 JP JP2004274673A patent/JP4375183B2/ja not_active Expired - Lifetime
-
2005
- 2005-06-28 TW TW094121661A patent/TW200610952A/zh not_active IP Right Cessation
- 2005-09-09 DE DE602005016506T patent/DE602005016506D1/de not_active Expired - Lifetime
- 2005-09-09 EP EP05019660A patent/EP1640703B1/en not_active Expired - Lifetime
- 2005-09-14 US US11/224,955 patent/US7981689B2/en active Active
- 2005-09-22 CN CNB200510106813XA patent/CN100570332C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7981689B2 (en) | 2011-07-19 |
| CN100570332C (zh) | 2009-12-16 |
| JP4375183B2 (ja) | 2009-12-02 |
| EP1640703A3 (en) | 2006-06-07 |
| DE602005016506D1 (de) | 2009-10-22 |
| JP2006090774A (ja) | 2006-04-06 |
| EP1640703A2 (en) | 2006-03-29 |
| EP1640703B1 (en) | 2009-09-09 |
| TW200610952A (en) | 2006-04-01 |
| CN1752741A (zh) | 2006-03-29 |
| US20060061760A1 (en) | 2006-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |