TWI232757B - Skin or hair treatment composition - Google Patents

Abstract

An external preparation characterized by comprising, as selected from gallic acid derivatives of the following formula (I), wherein R3 represents a hydrogen atom, an alkali metal, an alkaline earth metal, an ammonium salt, or an alkyl or alkenyl group having from 1 to 18 carbon atoms and R2, R3, and R4 independently represent a hydrogen atom, an hydroxyl group, an alkoxy group having from 1 to 18 carbon atoms, a polyoxyethylene group, a polyoxypropylene group, or a residue of a monosaccharide, a disaccharide, or an oligosaccharide; 90 wt% or over of one or more gallic acid derivatives (A) wherein two of R2, R3, and R4 in the formula (I) independently represent a residue of a monosaccharide, disaccharide, or oligosaccharide and from 0.001 wt% to less than 10 wt% of one or more gallic acid derivatives (B) wherein one of R2, R3, and R4 represents a residue of a monosaccharide, disaccharide, or oligosaccharide, each based on the total content of the gallic acid derivatives.

Description

1232757 A 7 B7 V. Description of the invention (1) Technical field (please read the precautions on the back before filling out this page) The present invention relates to preparations for external use with gluconoglucoside, in particular, the present invention relates to hairdressing products The formulation is applied to a topical preparation, in which the precipitation and sinking of the glucosinolate at low temperature is suppressed. BACKGROUND ART It is known that gallic acid and its esters have whitening, anti-oxidation, stiffening and elasticity of the hair, and treatment of hair damage caused by hair dyeing or perm agents (treating the next layer and microfibrils). ability. In fact, this kind of preparation is considered to be applicable in different fields, such as cream or emulsion skin external preparations, hair treatment agents such as hair conditioners or gels, and the like. However, the stability of gallic acid and its esters is generally poor. In the actual preparation process, the problem of coloring or precipitation makes it difficult for the product to exhibit its function or function satisfactorily. In addition, some types of gallates are generally insoluble in water, which may limit the amount used. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs To solve these problems, the Japanese Patent Laid-Open Publication 20000-3 1 9 1 1 6 proposes a method for glucosylation of gallic acid and its esters. Links sugar to phenolic hydroxyl groups of gallic acid. Although the solubility of this type of gallic glucoside at normal temperature has been improved, its solubility at low temperature is so low that when it is a solution of gallic glucoside in water, or its water / polarity When a solution in a mixed solvent of an organic solvent is left at a low temperature, a precipitate is formed. As mentioned above, the solubility of glucoside glucoside in water or a mixed solvent of water / polar organic solvent is low at low temperature, so it is accompanied by the sediment -4- This paper size applies the Chinese National Standard (CNS) A4 specification ( 210X297 mm) 1232757 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 37 A7 B7 V. Description of the Invention (2) Shen Zhi's Question. Illustrative contents of the present invention The object of the present invention is to provide an external preparation in which the precipitation of glucoside glucoside at low temperature is suppressed. In order to achieve the above-mentioned object, the present inventors conducted intensive investigations to suppress the precipitation of glucoside glucoside at a low temperature, and as a result, found that the gallic acid derivatives (A) and (B) represented by the following formulae in a specific amount When formulating external preparations, external preparations with excellent low-temperature stability can be obtained, and it is more suitable to add a cationic surfactant for further preparation. The present invention has been completed based on the above findings. The invention provides an external preparation, which is characterized in that it comprises a gallic acid derivative selected from the group consisting of the following formula (I): 0 0 (I), wherein R1 represents a hydrogen atom, an alkali metal, and an alkaline earth metal , Ammonium salts, or alkyl or alkenyl groups having 1 to 18 carbon atoms; R2, R3, and R4 independently represent hydrogen atoms, hydroxyl groups, alkoxy groups having 1 to 18 carbon atoms, polyoxidation Residues of vinyl groups, polyoxypropylene groups, or monosaccharides, disaccharides or oligosaccharides; 90% by weight or more of one or more gallic acid derivatives (A) wherein in formula (I) Two of R2, R3, and R4 represent the residues of monosaccharides, disaccharides, or oligosaccharides; This paper size applies to China National Standard (CNS) A4 specifications (210X297 mm) 5-(Please read the notes on the back first Please fill in this page for matters)

1232757 Α? B7 V. Description of the invention (3) (Please read the notes on the back before filling out this page) and one or more gallic acid derivatives from 0. 〇01% by weight to less than 10% by weight ( B) wherein one of R 2 'R 3 and r 4 represents the residue of monosaccharide, disaccharide or oligosaccharide, and each weight% is based on the entire content of the gallic acid derivative. Best Mode for Carrying Out the Invention The preparations for external use of the present invention are suitable as, in particular, hairdressing products. When the external preparation is selected from a gallic acid derivative represented by the following formula (I): 'It includes 90% (here and in the future, it represents weight%) or one or more formulae (I) a gallic acid derivative (A), in which two of R 2, R 3 and R 4 independently represent monosaccharide, disaccharide or polysaccharide residue, and from 〇〇〇〇1 At least 10% by weight of one or more gallic acid derivatives (B) represented by formula (I), wherein one of R 2, R 3 and R 4 represents a monosaccharide, a disaccharide or The oligosaccharide residues are each based on the total content of the gallic acid derivative represented by the formula (I). 〇 (1) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs

Note that R 1 represents a hydrogen atom, an alkali metal, an alkaline earth metal, an ammonium salt, an alkyl group or an alkenyl group having 1 to 18 carbon atoms, and the alkali metal which may be a part of R 1 includes: Na, K, Li, Etc. Alkaline earth metals include:

Ca, Mg, Ba, etc., and the alkyl or alkenyl group preferably has 1 to 10 carbon atoms. R 2, R 3 and R 4 independently represent hydrogen atom and hydroxyl group, and the paper size is applicable to Chinese National Standard (CNS) A4 (210X297 mm) -Θ 1232757 A7 B7 V. Description of the invention (4) (please first Read the notes on the reverse side and fill out this page) There are alkoxy groups of 1 to 18 carbon atoms (preferably those with 1 to 10 carbon atoms), polyoxyethylene groups, polyoxypropylene groups, or Residues of mono-, di- or oligosaccharides. The polyoxyethylene group is preferably represented by the formula— (〇C2H4) mH, where it is 100 (preferably 2 to 40), and the polyoxypropylene group is preferably of the formula— (〇C3H6) nH As shown, where n = 1 to 100 (preferably 2 to 40). Specific examples of the monosaccharide, disaccharide, or oligosaccharide residues include those of the following sugars: glucose, fructose, galactose, mannose, xylose, sucrose, lactose, bean beans, plant honey, fruit Oligosaccharides, Soy Oligosaccharides, Xylodioses, etc. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 3 £ In the practice of the present invention, one or more compounds of formula (I) (ingredient A) (where two of R 2, R 3 and R 4 independently represent monosaccharides The residue of disaccharides or oligosaccharides should be 90% or more, preferably 95% or more, and have one or more compounds of formula (I) (ingredient B) (where R2, R3 and One of R4 represents the residue of monosaccharide, disaccharide or oligosaccharide) should be present from 0.01% to less than 10%, preferably from 0.1% to 5%, each weight % Is based on the total content of gallic acid in formula (1). When the amount of component B in the formula is 0.01% or more, the component A can be controlled not to sink at low temperature, but if it is used more Satisfactory results cannot be obtained with a small amount of component B. In the formulation process, component B is less stable than component A at high temperatures, so if its amount in the formulation is 10% or more The resulting preparation may undergo color changes at high temperatures. For example, the component A includes: gallic acid-3,5-diglucoside. The paper standards are applicable to Chinese national standards. (CNS) A4 size (210X 297 mm) 1232757 A7 B7 V. invention is described in (5)

(Please read the notes on the back before filling in this page J; gallic acid-3,4-diglucoside; methyl gallate-3,5-diglucoside; ethyl gallate-3 , 5-diglucoside; propyl gallate-3,5-diglucoside; butyl gallate-3,5-diglucoside; gallic acid-3,5-dimannoside; Sodium gallate ~ 3,5-diglucoside; ammonium gallate-3,5-diglucoside. It is more suitable to use gallic acid-3,5-glucoside. On the other hand, The ingredient B includes, for example: gallic acid-3-glucoside, methyl gallate-3-glucoside, ethyl gallate-3-galactoside, propyl gallate-3- Glucoside, gallic acid-4-glucoside, sodium gallate-3-glucoside, ammonium gallate-4-glucosine, gallic acid-3-mannoside, gallic acid 4-Mannoside, methyl gallate-4-mannoside, etc. It should be noted that, in addition to ingredients (A) and (B), a gallic acid derivative of formula (I), its content Should not exceed 5%, preferably not exceed 1% (wt% is based on formula (1) Total content of gallic acid derivatives) 〇 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs As long as the gallic acid derivatives used in the present invention are composed of those compounds as defined above, they may be derived from plants Those obtained by extraction, or prepared by synthesis, may be anhydrous or water-containing. Although the preparation method of the gallic acid derivative is not strict, the derivative can be easily and efficiently obtained by the following method , Such as ... ... gallic acid or an ester thereof in a solvent with a sugar having a hydroxyl group completely or partially fluorinated, or a sugar halogenated at its anomer position in an acid catalyst (such as : BF 3 / E t20, SnC 1 4, ZnC 12 ', etc.) The reaction force is carried out in the presence of BF 3 / Et2 0, ZnC 12', etc. 乂 This paper size is applicable to China National Standard (CNS) 8-4 specifications (21〇 > < 297mm) -8 -1232757 A7 ____B7_ V. Description of the invention (6) (Please read the notes on the back before filling this page) You should 'get glucosylated product, and then, in the presence of acid or alkali', will protect the group- Exclude, if necessary, by extraction or column 〇1 至 20% 的 的 The chromatographic analysis method to purify it. In the practice of the present invention, the total content of gallic acid is not critical. When the external preparation is applied in a hairdressing type, the derivative can be 0.001 to 20% of The concentration should be adjusted from 0.1 to 10% (the total amount of the external preparation). If the total content of the gallic acid derivative is less than 0. 〇1%, satisfactory results cannot be obtained. On the other hand, when the total content exceeds 20%, the effect cannot be increased, so its economic benefits are poor. The preparation for external use according to the present invention preferably contains a cationic surfactant. Examples of the cationic surfactant include those shown below. (1) Amine salts and ammonium salts' R6-R5 ~ N + -R7 X (II) _ R8 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs where R5, R6, R7 and R8 independently represent hydrogen atoms, alkyl groups , Hydroxyalkyl, alkenyl, and polyalkyleneoxy groups or benzyl groups, the prerequisite is that one or two of R 5, R 6, R 7, R 8 independently represent a linear or branched chain An alkyl, hydroxyalkyl, or alkenyl group of 8 to 24 carbon atoms, and the remainder may be the same or different groups and independently represent a hydrogen atom, methyl, ethyl, benzyl or Polyalkylene oxide group, which is represented by one (C2H4〇), 1 ^ or one (C3H60) rH, wherein Q and r are each an integer of 1 to 5; X represents a derivative derived from an inorganic or organic acid Paper size applies to Chinese National Standard (CNS) A4 (210 X 297 mm) -9-1232757 A7 B7 V. Description of the invention (7) Anions, such as: Derived from chloride, bromide, iodide, sulfate, formaldehyde Sulfate, ethyl sulfate, acetate, pyrrolidone carboxylate, glycolate, citrate, succinate, p-toluenesulfonate Compounds, pyroglutamates, high fatty acid salts, acid amine salts, etc.) Guanidine salts CNA-II Η 〇-NC Η r ΝΗο X '(III) (Please read the precautions on the back before filling this page) Where R9 represents a linear or branched alkyl or alkenyl group having 1 to 21 carbon atoms; A represents a linear or branched alkylene or alkenyl group having 1 to 10 carbon atoms; t is 1 to An integer of 5 has a prerequisite that if t is 2 or more, A in the respective parts may be the same or different; X is as defined in the above formula (II). (3) benzyl ethoxylammonium salts

3S printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs

X " (IV) where R9 is as defined above; R1 and R11 may be the same or different and independently represent a hydrogen atom, a methyl group, an ethyl group, a benzyl group or a polyalkylene oxide group, which is (C2H4 〇) 〇 ^ 11 or one (represented by c3h6〇η 'where Q and r are each an integer of 1 to 5; X is as defined above. This paper size applies the Chinese National Standard (CNS) A4 specification (2ωχ 297 mm)- 10 1232757 A7 B7 V. Description of the invention (8) (4) Rhenium salt

(Please read the notes on the back before filling out this page) where R 9 and X are as defined above. (5) pyrrolidone carboxylates 9Ό 1X- (νι)

L r10 r J wherein R9, R1Q, R11, and X have the same definitions as above. There are other types of cationic surfactants based on amino acids, such as mono-N-long-chain alkaline amino acids with fluorenyl groups, which can be proposed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. Lower alkyl ester. The basic amino acids of this compound include, for example: natural amino acids such as: ornithine, lysine, arginine, etc. or 'synthetic amino acids, such as: ^, r -di Aminobutyric acid. These amino acids may be optically active substances or racemic substances. The fluorenyl group includes higher or lower saturated fatty acid residues having 8 to 22 carbon atoms. These fluorenyl groups can be of natural origin or synthetic type, such as ... mono-higher fatty acid residues' such as: lauric sulfonyl, myristyl, palmitoyl, stearyl, etc., which are all applicable. In addition, natural mixed higher fatty acid residues such as coconut oil fatty acid residues and high fatty acid residues of beef tallow and fat are applicable. The lower alkyl ester composition should preferably include: ethyl ester, ethyl ester, propyl ester, butyl ester, pentyl ester, hexyl ester, heptyl ester, and the Chinese paper standard (CNS) A4 specification (210X297 mm) applicable to this paper size _ 11 _ 1232757 A7 B7 V. Description of the invention (9) Octyl ester. The counter ion includes an ion having the definition of X in the foregoing formula. (Please read the precautions on the back before filling this page) Specific examples of cationic surfactants include stearyl trimethylammonium chloride, cetyltrimethylammonium chloride, behenyltrimethylammonium chloride, distearyl Osmium diammonium chloride, dioleyl dimethyl ammonium chloride, didecyl dimethyl ammonium chloride, ammonium laurate butyl guanidine acetate, myristic acid ammonium butyl guanidine acetate, ammonium palmitate Aminobutylguanidine acetate, distearyl hydrazone diammonium sulfate, stearyl ethyl dihydroxyethylammonium sulfate, N-coconut oil fatty acid L-arginine ethyl / DL-pyrrolidone carboxylate, etc. . These can be used alone or in combination with two or more of them. Among these, preferred are stearyl hydrazone triammonium chloride, distearyl dimethyl dimethyl ammonium chloride, and ammonium laurate butyl guanidine acetate. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs In the preparations for external use of the present invention, the content of the cationic surfactant can be appropriately controlled according to the end use of the preparation, and is not strictly limited. When the external preparation is used as a hairdressing product, the content of the cationic surfactant is from 0.01 to 20% of the total amount of the external preparation, preferably from 0.1 to 15%, and to 0.1. To 10% is better. If the content is less than 0.01%, a satisfactory low-temperature stabilizing effect of the cationic surfactant cannot be obtained. Conversely, when the content exceeds 20%, further effects may not be obtained, making the economic benefits poor. The type of water used in the present invention is not strictly limited, and city water, ion-exchanged water, distilled water, natural water, and the like can be used. The polar organic solvent is also not strictly limited and can be used generally for external preparations, with ethanol or isopropanol being preferred. Formulations for external use according to the present invention should be further adjusted together with silicone compounds. The paper size is applicable to Chinese national standard (0 milk) 8 4 specifications (210 乂 297 mm) -12-1232757 A7 B7 V. Description of the invention (10) ( Please read the notes on the back before filling out this page) to improve its usability when applied to hair. Examples of silicones include dimethyl polysiloxanes (including highly polymerized dimethyl polysiloxanes and silicone rubbers), toluene-based polysiloxanes, polyether-modified silicones, and amine-based Improved silicone, modified trimethylammonone lactone, alcohol modified sand, fluorine modified silicone, epoxy modified silicone, fluorenyl modified silicone, carboxyl modified silicon Ketones, fatty acid-modified silicones, silicone-grafted polymers, ring-shaped ketones, academic-based modified ketones, dimethylpolysiloxane terminated in trimethylsilyl, terminated in silanol Groups of dimethyl polysiloxanes, cross-linked alkyl polyether modified silicones, etc. Among these, polyether-modified silicones and amine-modified silicones are preferably used. These silicone compounds are preferably formulated with a surfactant to form an emulsion. Although the viscosity of silicones (except those of emulsion type) is not strictly limited, when considering the suitability of hair products, the viscosity should be between 10 and 1,000, 000 mm 2 / S at 25 ° C. In between, it is more preferably between 30 and 1,000, 000 mm 2 / S. In this section, the amount of the silicone compound is preferably selected from the range of 0.01 to 20%, and preferably 0.1 to 10% (based on the total amount of the external preparation). Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. In addition, in order to give hair stiffness and elasticity, it is appropriate to formulate gallic acid at 0.001 to 1% and / or sodium sulfate at 0. 0001 to 5%. Gallic acid can be extracted from natural products, or should be obtained synthetically, or it can be anhydrous or water-containing sodium sulfate can be anhydrous or water-containing. When using Glucoside Glucoside and Cationic Surface as described above-13- S Paper size Applicable Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 A7 B7 V. Description of the invention (11) Active agent When using preparations other than xanthone compounds as hair products, it can improve the rough hair, especially due to chemical treatment, such as perm or (please read the precautions on the back before filling this page). Coarse hair caused by exposure to ultraviolet rays or hair drying with a hairdryer. So far, the "improved hair dryness" situation has generally been limited to the dryness felt in the case of wet hair after shampooing. Most of the improvements are achieved by blending cationic compounds in shampoo, etc. (Japanese Patent Publication Hei 04-27381 1, He ei 06-40864, Hei 06- 34562 〇, Hei 0 8 — 143432, etc.) or formulating silicone into shampoo (Japanese Patent Laid-Open Publication Hei 06-32724, Hei 07-285836, Hei 07-316024, Hei 0 8- 3109 22, He ei 0 9 -1 2 4 4 3 7, etc.), and limit the types of detergents (Japanese Patent Laid-Open Publication Hei 05-124921, Hei 05- 125392, Hei 〇6 — 40864, Hei 07 — 258044, H ei 08 -12993, Hei 08- Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economy, 143432, Hei 09 — 157140, etc.). However, in most cases, its effect in bathing is not satisfactory and its use is therefore limited. The present inventors have found that the application of such a combination of the above-mentioned gallic glucoside, cationic surfactant, and silicone compound to the hair can significantly improve the condition of rough hair. gy This paper size applies Chinese National Standard (CNS) A4 specification (210X297 mm) -14-1232757 A7 B7 V. Description of invention (12) (Please read the precautions on the back before filling this page) Hairdressing products can be obtained when gluconic acid glucoside is formulated with ethanol. In this case, gallic acid should preferably be 0.01 to 10% (preferably 0.1 to 5%, more preferably 0.1 to 2%) and 5 to 90% (preferably 1 〇 to 60%, more preferably 10 to 30%) ethanol conjugation, if necessary, you can add 〇01 to 10% (preferably from 0.1 to 5%, from 0.1 to 5%) 3%) surfactants, and / or high molecular weight compounds from 0.01 to 30% (preferably 0.1 to 10%, more preferably 0.1 to 5%) to provide hairdressing products . When this hairdressing article is applied to the hair, glucoside can be completely penetrated into the hair, thereby achieving a high degree of color reduction prevention effect. When the hairdressing article is used, the color of the dyed hair can be prevented from fading and fading over time. Therefore, the beauty product can maintain hair color immediately after dyeing the hair. Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs, if necessary, in addition to the necessary ingredients, the preparations for external use according to the present invention may also include different types of ingredients commonly used in beauty products, similar drugs, etc. Within the range which will obstruct the effect of this invention. Such ingredients include, for example: anionic surfactants such as: α-olefin sodium sulfonate, α-olefin potassium sulfonate, sodium stearate, sodium palmitate, sodium laurate, sodium coconut fatty acid, arginine Stearates, arginine palmitates, arginine laurates, coconut oil fatty acid salts of arginine, sodium lauryl sulfate, sodium polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl ether ammonium sulfate, poly Sodium oxyethylene alkyl ether phosphate, sodium polyoxyethylene polyoxypropylene alkyl ether phosphate, sodium lauryl sarcosinate, sodium coconut fatty acid of methyl / 3 / 3-amino propionic acid, sodium dioctyl sulfosuccinate, poly Disodium ethylene oxide sulfosuccinate, sodium polystyrene sulfonate, disodium sulfosuccinate, N-lauric acid-N-methyl This paper is sized to the Chinese National Standard (CNS) A4 (210 × 297 mm)- 15-~ 1232757 A7 ____B7 V. Description of the invention (13)-/ 3 -Sodium aminopropionate, malic acid-sodium lauryl sodium, etc .; amphoteric surfactants, such as 2-alkyl-N-carboxyethyl N-Hydroxyethylimidazole (Please read the precautions on the back before filling Page) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 31. Porphyrin; Betaine, Coconut Oil Fatty Acid Aminopropyl Betaine, Lauryl Aminopropyl Betaine, Laurylamino Betaine, Hydrogenated Soy phospholipids, alkanediamine ethylglycine hydrochloride, N- [3-alkoxy-2-hydroxypropyl] -L-arginine hydrochloride, sodium laurylaminopropionate, etc. ; Non-ionic surfactants, such as: sugar fatty acid esters, sorbitan fatty acid esters, sorbitol fatty acid esters, polyglycerol fatty acid esters, glyceryl fatty acid esters, polyoxyethylene alkyl ethers, poly Ethylene oxide light fatty alcohol ethers, polyethylene oxide polyoxypropylene alkyl ethers, polyethylene oxide polyoxypropylene light fatty alcohol ethers, hydrogenated ramie oil, hydrogenated ramie oil fatty acid esters, polyethylene oxide hydrogenated ramie oil , Polyoxyethylene polyoxypropylene hydrogenated ramie oil fatty acid, etc .; oils, such as: isopropyl myristate, isopropyl palmitate, ethyl oleate, octadecanyl pivalate, butyl Octyl salicylate, cholate stearate, polyethylene oxide Alkene, liquid paraffin, liquid isoparaffin, squalene, squalane, ramie oil, jojoba oil, hazelnut oil, sweet almond oil, grape seed oil, tea plum oil, safflower oil, olive oil, colchicine oil, rose Oil, avocado oil, etc .; polymers such as: hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, cationized cellulose, polyvinylpyrrolidone, polyvinyl alcohol, acrylic acid / methyl Acrylic copolymers, carboxystyrene polymers, etc .; amino acids such as: glycine, ornithine, protein amine, alanine, arginine, glutamate 'cysteine, sulfalanine, Cysteine, leucine, isoleucine, aspartic acid, lysine, phenylalanine ', etc .; plant extracts, such as: rosemary' pepper seeds, sheep's hoof, aloe, citric acid scale applicable to China National Standard (CNS) A4 Specification (210X297 mm) "16-'-1232757 A7 _B7 V. Invention Description (14) (Please read the notes on the back before filling this page) Goji, mugwort, mustard, rice plant , Licorice, lily, white birch, sophora flavescens, courgette, oil tree, arnic, etc. Seaweed extracts, such as: seagrass ash, chlorella, Norwegian seaweed, coral algae, unicorn, etc .; polyhydric alcohols, such as propylene glycol, dipropylene glycol, glycerol, butanediol, etc .; preservatives, such as p-oxybenzene Formates, parabens, etc .; release agents, such as: edetate, pyrophosphate, citrate, glycolate, tartaric acid, etc .; gas, such as liquid petroleum gas, dimethyl Ether, nitrogen, carbon dioxide, etc .; antioxidants, such as: dibutyl hydroxytoluene, butyl hydroxy anisole, dilauryl dilauryl thiopropionate, sodium sulfate, sodium sulfite, vitamin E, ascorbyl dipalmitate, etc. UV absorbers, such as: p-aminobenzoic acid derivatives, salicylic acid derivatives, cinnamic acid derivatives, phenol, hydroquinone, dihydroxydimethoxybenzophenone, etc .; p p regulators, Such as: succinic acid, citric acid, tartaric acid, lactic acid, glycolic acid, etc .; Vitamins, dyes, and cooling agents, such as: 1-menthol and its derivatives, moisturizers, thickeners, etc. The perfume composition printed by the consumer cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs can also be used in the preparations for external use of the present invention. In this case, the blending amount of the fragrance composition is preferably from 0.00001 to 10%, more preferably from 0.0001 to 5%, of the total amount of the external preparation. There are no strict restrictions on the types of external preparations, and the preparations can be used in the following different types, such as different types of solutions, emulsions, dispersions, oil-water double-layer systems, and can be sprayed, flakes, gels, creams, coatings , And other types to use. Further, the preparation for external use of the present invention can be immersed in a non-woven fabric and used as a cloth sheet. Therefore, the external preparation can be used as hair conditioner, hair lotion, hair lotion, hair spray, shampoo, conditioner, and conditioner. The paper size is applicable to the Chinese National Standard (CNS) A4 specification (210 X 297 mm). -17-1232757 Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs A7 B7 V. Description of invention (15), therapeutic agents, skin creams, skin cosmetics, whitening agents, shaving gum, and other types of use. These can be prepared according to ordinary methods for individual versions. If a container is required for actual application, the material and shape of the container are not limited to any particular kind. The materials of this type of container include polypropylene, polyethylene terephthalate, polyethylene, EVA (ethylene vinyl alcohol copolymer resin) and its sheet, sheet with aluminum foil layer, tin sheet, aluminum, glass, etc. The types of containers include the commonly used types, such as: spray gun containers, torches, spray containers, tubular containers, canisters, pillow packaging, small containers, micelles, and so on. The external preparations of the present invention can be used in all different external preparation types (including preparations for animals). In particular, medicines, drugs and beauty products that can be used topically or widely (including, for example, body soaps, skin creams, whitening agents, shampoos, conditioners, conditioners, treatments, perms Liquid, hair dye, hair conditioner, hair conditioner, hair restorer, therapeutic hair conditioner, etc.), used in micelles, liquids, gels, ointments, lozenges, and granules. In particular, the preparation of the present invention is suitable as a hairdressing article. Examples The present invention is described in detail by the following examples, which should not be used to limit the present invention. Comparative examples are also described below. In these examples, the percentages are by weight. ^ Examples 1 to 16 and Comparative Examples 1 to 4 The samples of Examples 1 to 16 and Comparative Examples 1 to 4 have Table 1 I:: --- ^^ 装 ---- ^ --- Order ^ ------ (Please read the notes on the back before filling this page) The paper size is applicable to China Standard (CNS) A4 specification (210X297 mm) 18-1232757 A7 B7 V. Description of the invention ( 16) and the formulations indicated in Table 2, these samples were prepared in the usual manner, and each was placed in a 50 ml glass container, and the containers were each placed at a temperature of 10 ° C and 5 ° C. 0 ° C air-cooling / heating-in a temperature-adjusting box, to determine by visual observation the number of days before the precipitation can be seen, and the number of days before the sediment changes color, in order to evaluate These samples. The results are shown in Tables 1 and 2. It should be noted that this ρ Η 値 is adjusted to 3 to 7 by using glucic acid (g 1 u c ο 11 i c a c i d) or glycolic acid. Evaluation of stability: X = 0 to 14 days, a = i 5 to 30 days, 0 = 31 to 40 days, 1 day or longer. (Please read the notes on the back before filling out this page) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs This paper size applies Chinese National Standard (CNS) A4 specification (2 丨 〇 > < 297 mm) 1232757 A7

7 B V. Description of Invention (17) Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs

Unit:% Ingredients Example Specific Example s Compared to Example 1 2 3 4 5 6 7 8 1 2 Gallate-3.5-Diglucoside 1.0 1.0 1.0 1.0 Methyl Gallate-3,5-Diglucoside 1.0 1.0 ethyl gallate-3,5-diglucoside 1.0 propyl gallate-3,5-diglucoside 1.0 gallic acid-3,5-dimaltoside 1.0 1.0 gallic acid Each glucoside 0.05 0.02 0.01 0.01 0.01 0.2 methyl gallate-3-glucoside 0.05 0.02 0.01 0.01 0.01 stearyl trimethylammonium chloride 1.0 1.0 0.5 0.5 0.5 butan-U-diol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Aminoethylaminopropylmethylsiloxane / dimethylsiloxane copolymer emulsion 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Glycolic acid moderately moderate moderately moderate moderately moderately moderately moderately Disodium acid 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Ethanol 20 20 20 20 20 20 20 20 20 20 20 Water balance balance balance balance balance balance balance all (%) 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Low temperature stable 〇〇 ◎ 〇〇 ◎ 〇〇X 〇 High temperature stability ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ X (Please read the precautions on the back before filling out this page) This paper size is applicable to China National Standard (CNS) A4 specifications ( 210X297 mm) -20- 1232757 A7 _____B7 V. Description of the invention (18) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Unit:% Ingredients Real 1 _ Comparative Example 9 10 11 12 13 14 15 16 3 4 No food Gallic acid-3.5-diglucoside 2.0 1.0 1.0 1.0 gallic acid-3.5-dimaltoside 2.0 1.0 1.0 1.0 ethyl gallate-3.5-dimaltoside 2.0 1.0 1.0 1.0 propyl gallate-3.5 -Dimaltoside 2.0 L0 1.0 1.0 gallic acid-3.5-glucoside 0.1 ethyl gallate-3-glucoside 0.1 propyl gallate-3-glucoside 0.1 methyl gallate-3 -Maltoside 0.1 ethyl gallate maltoside 0.1 0.1 propyl gallate-3-maltoside 0.1 0.1 stearyl trimethylammonium chloride 0.5 0.5 0.5 0.5 0.5 0.5 0.5 gallic acid 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 Sodium sulfate 0.001 0.001 0.001 0.001 0.001 0.001 0.001 αοοι 0.001 0.001 Aminoethylaminopropylmethylsiloxane / dimethylsilazane copolymer emulsion 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Lauryl dimethylamino betaine 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Propanediol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Glycolic acid appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount appropriate amount Sodium pyrophosphate 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Hydroxyethyl cellulose 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Ethanol 15 15 15 15 15 15 15 15 15 15 15 Water balance balance balance balance balance balance balance balance all (%) 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Ichan stable macro _ ◎ 〇〇 ◎ ◎ ◎ 〇〇X Δ 莒 借 借: ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎ (Please read the precautions on the back before filling in this page ) This paper is a standard for financial rewards (CNS) M specification (21 () > < 297 Gongling) -2T ^ 1232757 A7 B7 Description of the invention (19) Examples 17 and 18 and Comparative Examples 5 to 8 (Please read the precautions on the back before filling out this page) Prepare a cleansing hair care product with the formula indicated in Table 3 ' The roughness of the hair was evaluated as follows. The evaluation method asked 20 members of the test group suffering from hair damage caused by dyeing or perming to apply each hair care product, and compared the situation before using the product according to the following evaluation criteria after use to evaluate the rough hair situation. < Evaluation criteria >: Among the 20 test panel members, not less than 16 members answered that it was better after application than before. Ο: Among 20 test panel members, 10 to 15 members answered that it was better after application than before application. △: Among the 20 test group members, 4 to 9 members answered that it was better after application than before. Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs > 3, X: Of the 20 members of the test group, less than 4 members responded better than before the application. This paper size applies Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 A7 B7 V. Description of invention (20) 塾

Formulation ingredient (%) Example SS Comparative Example I 17 18 5 6 7 8 Gallic acid-3.5-diglucoside 1 0.5 1 1 Gallic acid-3-glucoside 0.05 0.02 Stearyl trimethyl chloride Note 1 1 1 1 1 Silicone 1 Note 2 5 5 5 Silicone 2 Note 3 10 Polyethylene oxide (30) stearyl ether Note 4 0.2 0.2 0.2 0.2 0.2 0.2 Liquid paraffin 10 Ethanol 10 10 10 10 10 10 Fragrance 0.1 0.1 0.1 0.1 0.1 0.1 Pure water balance Balance balance Balance balance All 100 100 100 100 100 100 100 Rough ◎ ◎ Δ Δ 〇X (Please read the precautions on the back before filling this page) Note 1: ARQUADT-8 00 (Lion Chemical Co., Ltd.) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. Note 2: KSG 2 1 (Shin-Izu Silicone Co., Ltd .: Cross-connected polyether-modified polyketone / methyl polyoxygen compound) Note 3: KSG 31 (Shin-Izu Silicone Co., Ltd .: Cross-linked type of alkyl polyether modified silicone / liquid paraffin mixture) Note 4: EMALEX 63 0 (Yueben Emulsion Co., Ltd.) This paper size applies to China National Standard (CNS) A4 Specification (Γ23-1232757 A7 B7 V. Description of the invention (21) Example 1 9 Aqueous liquid preparation (please read the precautions on the back before filling this page) Prepare a dispenser-type aqueous liquid preparation with the following formula and insert it into a UV-embedded unit. Absorbent made of PET in a cartridge dispensing container. Gallic acid-3,5-diglucoside 0.4% gallic acid-3-glucoside 0.01 sodium sulfate 0.001 lauryldimethylaminoacetic acid betaine 5.0 Stearyl trimethylammonium chloride 3.0 N-vinylpyrrolidone-N, N-dimethylamine ethyl methacrylate 0.5 N-methacryloxydiethyl-N, N-dimethylamine ethyl -A -N-methylcarboxybetaine / alkyl ester methacrylate copolymer (Yuka fomeme510, manufactured by Mitsubishi Chemical Corporation) 1.0 Hydrolyzed keratin (Proticute ua, manufactured by (Manufactured by ICHIMARU PHARC0S Co., Ltd.) 2.5 Hydroxybenzone 0.1 Methyl para-hydroxyperbenzoate 0.1 P-hydroxyl perbenzoate 0.1 Consumers' cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs Printed Sodium Pyrohydrate Anhydrous 0.005 Triethanolamine 1.0 Fragrance 0.1 Ethanol 20.0 Pure water _ balance all 100.0% paper size Appropriate Financial Standards (CNS) A4 (21GX297mm) -24-~ — 1232757 Α7 Β7 V. Description of the Invention (22) Example 20 (Please read the precautions on the back before filling this page) Spray Hair Formulation Prepare hair conditioner with the following formula and pour it into an aluminum spray pressure tank. (Storage solution) methyl gallate-3,5-diglucoside 0.25% gallic acid-3-glucoside 0.02 sodium sulfate 0.005 coconut oil fatty acid amidopropyldimethylamine acetate betaine 1.0 dl-α -Tocopherol acetate 0.5 Distearyl dimethyl ammonium chloride 1.5 1-Menthol 0.2 Spice 0.05 Ethanol 40.0 Pure water balance Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economy All 60.0 (gas) LPG 30.0 DME__10 .0 All 100.0% Example 2 1 Cost The paper size applies the Chinese National Standard (CNS) A4 specification (210X297 mm) -25-1232757 A7 B7 V. Description of the invention (23) Non-aerosol tincture and blister preparation (please first Read the notes on the back and fill out this page) Prepare a foam preparation with the following formula and pour it into a cylinder foam container. This container is made of polypropylene with UV absorber embedded. Note that the P system is adjusted to 4.5. Gallic acid-3,5-dimaltoside 0.2% gallic acid-3-glucoside 0.015 sucrose ester laurate 0.5 butylguanidine-ammonium acetate laurate 1.0 3-methyl-1,3-butane Diol 10.0 Silicone Emulsion (FZ-4188, manufactured by Unicar Japan Ltd.) 8.0 Amine-modified silicone emulsion (FZ-4672, manufactured by Unicar Japan Ltd.) 5.0 Polyethylene oxide (30) stearyl ether 0.6 lauryl dimethylamine oxide 0.5 plant-derived squalane 0.1 water-soluble collagen (Neptigen, incomplete type, manufactured by ICHIMARU PHARCOS Co., Ltd.) 1.0 Ministry of Economy Wisdom Property Bureau employee consumer cooperative prints methyl parahydroxyperbenzoate 0.1 propyl parahydroxyperbenzoate 0.05 aniline chloride 0.1 dibenzophenone sulfonic acid (trihydrate) 〇1 citric acid 0-5 three Appropriate amount of ethanolamine 4¾ This paper size is applicable to Chinese National Standard (CNS) A4 specification (210X297 mm) -26- 1232757 A7 B7 V. Description of the invention (24) Fragrance 0.1 Ethanol 20.0 Pure water balance (please read the precautions on the back before filling (This page) All 100.0% Example 2 2 Spray Gun Hair Treatment Healing Agents Prepare hair treating agents with the following formulations and pour them into a spray gun type PET container. The pH is adjusted to 4.3. Gallic acid-3,5-diglucoside 0.3% Gallic acid-3-glucoside 0.012 Gallic acid 0.001 Sodium sulfate 0.001 Lauryl dimethylaminoacetic acid betaine 1.5 Stearyl trimethylammonium chloride 2.0 Polypropylene oxide (9) diglyceryl ether 1.0 Propylene glycol 4.0 Polyethylene oxide / methyl polysiloxane copolymer 1.0 Employees' Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs printed hydrolyzed silk liquid (Silkgen G soluble S, by Manufactured by ICHIMARU PHARCOS Co., Ltd. 1.0 Hydroxypropyl polychitosan solution (Chitofilmer, manufactured by ICHIMARU PHARC0 Co., Ltd.) 1.0 Dihydroxybenzophenone sulfonic acid 0.1 p-hydroxyperbenzoate 0.1 Paper size applies Chinese National Standard (CNS) A4 specification (210X297 mm) -27 ^-1232757 A7 B7 V. Description of the invention (25) Anhydrous sodium pyrophosphate 0.05 An appropriate amount of rod-like acid Sodium citrate (please read first Note on the back, please fill in this page again) Ethanol 20.0 Fragrance 0.05 Pure 7jC_ Equilibrium 100.0% Example 2 3 Gels Prepare gels with the following formula and put them into a cylindrical container. The container is made of Built-in UV absorption Made of P E T. Adjust p Η 値 to 4.4 and adjust the viscosity to 1 500 to 30.0 OPa Ellagic acid 0.05% Gallate-3,5-diglucoside 0.5 Gallate-3-glucoside 0.001 Lactic acid 0.0005 Printed sodium sulfate 0.001 Employee Consumption Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs Stearate trimethylammonium chloride 2.5 Polyethylene oxide (40) Hydrogenated ramie oil 3.0 Silicone emulsion (FZ-4 188, Japan Unica Limited) Company) 5.0 Polyethylene oxide / methyl polysiloxane copolymer 1.0 4Θ 3 This paper size applies to Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 Α7 Β7 V. Description of the invention (26) Chamomile extract 1.0 Japanese wolfberry Leaf extract 1.0 decaglyceryl-isostearate 2.0 dihydroxybenzophenone 0.1 hydroxyethylcellulose moderate para-hydroxyperbenzoate 0.3 anhydrous sodium pyrophosphate 0.2 sodium sulfite 0.1 glycolic acid appropriate dibutylhydroxytoluene 0.001 Ethanol 20.0 Fragrance 0.05 Pure water balance (please read the precautions on the back before filling this page) All 100.0% Example 2 4 Hair dispenser of hair dispenser dispenser Printed by the Consumer Cooperative of Intellectual Property Bureau of the Ministry of Economic Affairs The hair spray prepared with the following formulation, and Chen made it into a polyethylene tube into a dispensing container's expense. Adjust P Η 値 to 5 _ 0. Gallic acid-3,5-diglucoside 0.5% gallic acid-4-glucoside 0.005 sodium sulfate 0.001 N-coconut oil fatty acid L-arginine ethyl / DL-pyrrolidone carboxylate Acidification 2.0 This paper size applies Chinese National Standard (CNS) A4 specification (210 × 297 mm) 1232757 A7 _____ _B7 V. Description of the invention (27) Emulsion * 70% sorbitol solution birch extract polyethylene oxide / fluorene-based poly Silicone copolymer blueberry extract hydroxymethoxyphenone p-hydroxyperbenzoate methyl ethyl citrate sodium citrate flavor ethanol pure water 3 ο quantity 2 dust production ο ,,,, and equilibration (please read the back first Please note this page and fill in this page again) ^ pP 100.0% * At 90 ° C, emulsify 5% carnauba wax, 7% polyethylene oxide (15) lauryl ether and 88% pure water (average particle size is 1.0) 〇nm). Example 2 5 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Aerosol Cells An aerosol cell is prepared with the following formula. Use an aluminum pressure tank as the container. -30- 4.Q.5 This paper size is applicable to Chinese National Standard (CNS) A4 specification (2! OX297 mm) 1232757 A7 B7 V. Description of the invention (28) (Storage solution) Gallic acid-3,5- Diglucoside 1.0% (Please read the notes on the back before filling this page) Gallic acid-4-glucoside 0.01 sodium sulfate 0.005 cationic cellulose (XK-503, manufactured by Lion Company) 0.4 sodium hyaluronate 1.0 Dipropylene glycol 6.0 Stearyl trimethylammonium chloride 2.5 Amine-modified silicone (SF 8452C, manufactured by Torre-Dow Corning Silicone Co., Ltd.) 2.0 Polyoxyethylene (60) hydrogenated ramie oil 1.0 Hydrolyzed horny 1.0 N-coconut oil fatty acid fluorenyl-L-alginin ethyl / DL-pyrrolidone carboxylate 0.5 trimethylglycine (Aquadew AN-100, manufactured by Ajinomoto) 0.5 carboxyvinyl polymer 0.5 Triethanolamine solution (30% aqueous solution) 0.05 Shea Butter oil 1.0 Fragrance printed by employees' cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs 0.1 Ethanol 20.0 Pure water_balance all 92.0 (gas) LPG gas_8 ^ all 100% 43 € paper size Applicable Chinese national standard (milk) 8 4 specifications (210 297 mm) 31-1232757 A7 B7 V. Description of the invention (29) Example 2-(Please read the precautions on the back before filling this page) Hair Wax Prepare hair buns with the following formula and put them into a pot type In the container 'This container is made of antistatic agent and polypropylene with UV absorber embedded. Gallic acid-3,5-diglucoside 0.5% Gallic acid 3-glucoside 0.001 Dimyristyl dimethylammonium chloride 3.0 Gallic acid 0.001 Sodium sulfate 0 · 0 01 Decaglyceryl diisostearate 5.0 Carboxyvinyl polymer 0.5 Xanthan gum 0.25 Water-soluble solid silicone (KF-6004, manufactured by Shin-Izu Chemical Co., Ltd.) 2.0 Silicone powder (Tospearl 2000B, Manufactured by Toshiba Silicone Co., Ltd. 1.0 Hydrolyzed silk liquid printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs (Sihara G Soluble S, manufactured by ICHIMARU PHARC0S Co., Ltd.) 0.5 Vaseline 3.0 Sauce 2.0 Candelilla wax ) 1.0 Apple extract 2.0 Polyoxypropylene (14) diglyceryl ether 4.0 487 The paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 A7 B7 V. Description of the invention (30) Dihydroxybenzophenone 0.1 methyl para-peroxybenzoate 0.3 tetrasodium edetate 0.05 triethanolamine 0.5 perfume 0.05 ethanol 5.0 pure water balance (please read the precautions on the back before filling this page) All 100.0% Examples? 7 Gels Prepare gels with the following formula and pour them into a tubular container. This container is made of polypropylene with antistatic and embedded UV absorber. Gallic acid-3,5-diglucoside 0.5% Gallic acid-4-mannosid 0.02 Stearyl trimethylol chlorinated sodium chloride 5.0 sodium sulphate 0.001 Intellectual property bureau of the Ministry of Economic Affairs, Employee Consumption Cooperative Printed with alkyl modified Carboxyvinyl polymer 0.5 Xanthan gum 0.25 Silicone paste (KSG-21, manufactured by Shin-Izu Chemical Co., Ltd.) 5.0 Water-soluble solid silicone (KF-6004, manufactured by Shin-Izu Chemical Co., Ltd.) 2.0 Silicone powder (Tospearl 2000B, manufactured by Toshiba Silicone Co., Ltd.) 1.0 This paper size applies to China National Standard (CNS) A4 specification (21 × X 297 mm) " " 33: 1232757 Employees ’Intellectual Property Bureau of the Ministry of Economic Affairs employee consumption Printed by the cooperative # 一 A7 B7 V. Description of the invention (31) Hydrolyzed silk liquid 0.5 polyethylene oxide (20) stearyl ether 4.0 hydroxybenzophenone 0.1 para-hydroxyperbenzoic acid methyl ester 0.3 triethanolamine 0.5 perfume 0.05 Ethanol 15.0 pure water balances all 100.0% Example 2 8 Shampoo A shampoo was prepared with the following formula: and shoved into a cylinder container: This container is made of an antistatic agent and an embedded UV absorber. Made of acrylic. Gallate-3,5-Diglucoside 0.5% Propyl gallate-3 -Mannoside 0.01 Behenyltrimethylammonium chloride 0.5 Sodium sulfate 0.001 Sodium lauryl sulfate 10.0 Sodium α-enesulfonate 5.0 Fatty acid Diethanolamine 5.0 Alkylamine Propyl Betaine 5.0 (Please read the precautions on the back before filling out this page} Highly Polymerized Dimethyl Silicone (BY11-003, by Torre-Dao Paper Size Applicable to China National Standard (CNS) A4 Specification (210X 297 mm) 1232757 A7 __B7 V. Description of Invention (32) Made by Corning Silicone Co., Ltd. 3.0 Cationic cellulose (XK-503, manufactured by Lion Company) 0.5 Glycol Distearate 2.0 (Please read the precautions on the back before filling in this I) Aloe vera extract 〇2 sodium benzoate 〇8 fragrance 〇05 pure 7jc_ balance all 100.0% Example 2 9 conditioner preparation The following formula of emollients is put into a canister, which is made of antistatic agent and polypropylene with UV absorber embedded. Gallate-3,5-dimaltoside 0.5% gallic acid-3-maltoside 0.02 gallic acid 0.002 sulfuric acid 0.001 Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs, Stearyl trimethylammonium chloride 1.0 Distearyl trimethylammonium chloride 0.5 Cetyl stearyl alcohol 3.0 P〇E (5) Stearyl ether 1.5 Liquid paraffin 1.0 Cyclooxane (DC246, manufactured by Torre-Dow Corning Silicone Co., Ltd.) 0.5 «G This paper size is applicable to the Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 A7 __ _ B7 V. Description of the invention (33) Methyl Silicone (SH200-500cs, manufactured by Torre-Dow Corning Silicone Co., Ltd.) 5.0 Mallow Extract 0.2 Para-Methyl Hydroxy Perbenzoate 0.1 Fragrance 0.1 Pure Water _ Balanced All 100.0%

Example 3 I Cream Prepare a cream with the following formulas A and B. This is to dissolve A and B at 70 ° C, add A and B to obtain a uniform emulsion, and then add C during cooling. And put it into a tube made of aluminum sheet to complete it (please read the precautions on the back before filling this page) Printed in the oil phase part of the squalane 5.0% ethyl oleate 2.0 Oil-based dodecyl myristate 1.5 Liquid stone mash 1.0 Polyethylene glycol (40EO) -stearate 3.0 Coconut oil fatty acid sorbitan ester 2.0 Glycerin monostearate 1.0 Cetylstearate Alcohol 1.0 p-Hydroxyperbenzoic acid propyl 0.1 This paper size applies to Chinese National Standard (CNS) A4 (210 X 297 mm) 1232757 A7 B7 V. Description of the invention (34) B gallic acid in water phase- 3,5-dimaltoside 0.5 gallic acid 4-maltoside 0.03 palmityl trimethylammonium chloride 0.3 sodium sulfate 0.001 butane-1,3-diol 2.5 dipropylene glycol 2.5 para-hydroxyperbenzoate 0.25 licorice Dipotassium Acid 0.2 Gentian Extract 0.1 Pure Water Balance C Fragrances 0.05% Whole 100.0% (Please read the precautions on the back before filling this page)-Binding and ordering Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs Example 3 1 Hair conditioner Prepare hair conditioner with the following formula and mix it in Telescopic glass container. Ethyl gallate-3,5-dimaltoside 1.0% methyl gallate-4-maltoside 0.05 pentaeryl triethylammonium chloride 1.0 sodium sulfate 0.007 POE (8) oleyl ether 1.5 Glycerin 3.0 ^ This paper size applies the Chinese National Standard (CNS) A4 specification (210X297 mm) 1232757 A7 B7 V. Description of the invention (35) L-menthol 0.1 Sundol 0.3 Methyl para-peroxybenzoate 0.1 Spice 0.05 Ethanol 70.0 Pure water balance all 100.0% Example 3 2 (Please read the precautions on the back before filling out this page) Hair repair and growth hair preparation Prepare hair repair and growth hair preparation with the following formula and mix it in Sleeve type polyethylene container. Ethyl gallate-3,5-diglucoside 1.0% gallic acid 3-glucoside 0.02 stearyl triammonium ammonium chloride 0.5 POE (10) oleyl ether 2.0 DL-α-tocopherol Acetate 0.1 Sucrose ester Myristate 0.5 Biotin printed by the Consumers ’Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 0.02 Succinic acid 0.3 Aqueous herb extract 1.0 Nitrogen alcohol 0.1 L-menthol 0.3 methyl para-hydroxyperbenzoate 0.1 413 This paper size is applicable to Chinese national standard (0 milk) 8 4 specifications (210 乂 297 mm) 1232757 A7 B7 V. Description of the invention (36) Spices 0.05 Ethanol 40.0 Pure water balance all 100.0% Example 3 3 Hair growth spray Hair Conditioner (Please read the notes on the back before filling this page) Prepare hair conditioner with the following formula and pour it into a tin pressure tank. (Storage solution) methyl gallate-3,5-diglucoside 0.3% methyl gallate-3-glucoside 0.01 butylguanidine acetate stearate 3.0 N -pentadecane isoleucine Acid 0.3 Sorbitol Anhydride Laurate 1.0 Amphoteric Polymer (Yukafel 201, manufactured by Mitsubishi Chemical Co., Ltd.) 0.5 Citric Acid 0.1 Sucrose Ester Laurate 2.5 L-Menthol 0.5 Intellectual Property Bureau Employees Cooperative Cooperative Printed ethanol 20.0 Pure water balance all 80.0 (gas) LPG_20.0 all 100.0% This paper size applies Chinese National Standard (CNS) A4 specification (210X297 mm) -ay 1232757 A7 B7 V. Description of the invention (37 Example 3 4 Aerosol foam: Prepare an aerosol foam with the following formula and pour it into a PET pressure tank. Methyl gallate-3,5-diglucoside 0.3% methyl gallate-3-glucose Glycoside 0.01 Sodium sulfate 3.0 E 0 modified ketone 0.3 Piroctone olamin (Piroctoneolamin) 1.0 Amphoteric polymer (Yukafoamer 204, by three (Please read the notes on the back before filling in this Page) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs

(Manufactured by Ryo Chemical Co., Ltd.) stearyl trimethylammonium chloride POP (9) diglyceryl ether POE (20) sorbitan monooleate flavor ethanol pure water all (gas) LPG DME 0.5 0.1 0.1 2.5 0.5 20.0 Balance 80.0 10.0 10.0 All 100.0% This paper size applies to Chinese National Standard (CNS) A4 (210X297 mm) 1232757 A7 B7 V. Description of the invention (38) Example 3 5 For fixing messy or curled hair Preparations Preparations for fixing messy or curled hair with the following formula (please read the precautions on the back before filling out this page) Printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs and put them in PET containers. Methyl gallate-3,5-diglucoside 2.0% methyl gallate-3-glucoside 0.01 sodium sulfate 0.06 amino modified silicone 3.0 polyvinylpyrrolidone 0.4 cationic cellulose (XK-503, manufactured by Lion Company) 0.5 P0P (14) diglyceryl ether 4.0 Arginic acid 0.5 Sorbitol solution 2.5 Stearyl trimethylammonium chloride 0.5 POE (50) hydrogenated ramie oil 0.5 Oxygen Benzophenone sulfonic acid 0.1 p-hydroxyperbenzoate 0.1 dibutyl hydroxytoluene 0.05 Spice 0.5 Green No. 3 Very small amount of citric acid Ethanol 15.0 Pure water balance all 100.0% 44G This paper size applies to China National Standard (CNS) A4 specifications (210X297 mm) 1232757 Α7 B7 V. Description of the invention (39) Example 3 6 Gel for eyebrows or eyelashes (please read the precautions on the back before filling this page) Prepare the following formula for eyebrows or Gels of eyelashes' and scoop them into a glass eyebrow dye container. p Η 値 system is adjusted to 7. Methyl gallate-3,5-dimaltoside 2.0% methyl gallate-3-maltoside 0.01 stearyl trimethylammonium chloride 2.0 gallate 0.002 sodium sulfate 0.005 polyether modified silicon Ketone (ΒΥ22-008M, manufactured by Torre-Dow Corning Silicone Co., Ltd.) 1.0 Amphoteric polymer (Yukafoamer 205, manufactured by Mitsubishi Chemical Co., Ltd.) 1.0 Carboxyvinyl polymer 0.5 Deca glyceryl monostearate Ester 4.0 POE (30) isocetyl ether 0.5 p-hydroxymethyl perbenzoate 0.1 sodium hydrogen sulphite 0.05. Disodium edetate 0.05 printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs. 5 Triethanolamine Amount of ethanol 10.0 Pure water _ Balanced all 100.0% 41 / This paper size applies Chinese National Standard (CNS) A4 Specification (210X297 mm) -42- 1232757 A7 B7 V. Description of the Invention (4〇) Example 3 7 Cream (Please read the precautions on the back before filling this page) Dissolve the following formulas A and B at 70 ° C, add B to A to obtain a uniform emulsion, and then add C during the cooling period to Preparation of cream. It was scooped into a polyethylene container. A oil phase part of liquid lycox 5.0% squalane 15.0 cetyl stearyl alcohol 5.0 glyceryl monostearate 2.0 POE (20) sorbitan monolaurate 2.0 propyl parahydroxybenzoate 0.1 B Aqueous phase methyl gallate-3,5-dimaltoside 2.0 methyl gallate-3-maltoside 0.1 distearyl dimethylammonium chloride 0.1 gallic acid 0.001 Ministry of Economic Affairs intellectual property Bureau ’s Consumer Cooperative Co., Ltd. printed sodium sulfate 0.001 p-hydroxymethyl perbenzoate 0.2 green earth 1.0 pure water balance C fragrance _0.05 all 100.0% 41 spider paper scale applies Chinese national standard (〇 奶) 8 4 specifications (210 father 297 (Mm) 1232757 A7 B7 V. Description of the invention (41) Example 3 8 (Please read the precautions on the back before filling out this page) Ointment Prepare ointment with the following formula and pour it into a polypropylene tank type Container. Propyl gallate-3,5-diglucoside 0.5% propyl gallate-3-glucoside 0.04 stearyl trimethylammonium chloride 4.0 gallic acid 0.001 sodium sulfate 0.001 white petrolatum 40.0 cetane Alcohol 18.0 Sorbitan sesquimonooleate 5.0 lauromacrogol 0.5 Fan pepper tincture 0.01 Poison sea mango extract 1.0 Spices 0.2 Pure water printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs_Balance all 100.0% Example 3 9 Body lotion 41: 3 ^ Paper size applies Chinese national standard (milk) 8 4 specifications (210 乂 297 mm) 1232757 Α7 Β7 5. Description of the invention (42) Preparation of body makeup with the following formula Liquid and use aluminum film to scoop it into a pillow-shaped package. Gallic acid-4-maltoside 0.5% (Please read the notes on the back before filling out this page) Gallic acid-3,5-diglucoside 15.0 Gallic acid-4-glucoside 0.8 Gall Acid 0.002 Sodium Sulfate 0.003 Sensitization Dose 1.0 Monoglyceride Pentadecenoate 3.0 Tocopherol Acetate 0.1 Oxidative Coenzyme 0.001 Elliptic Acid 0.02 Ethyl Alcohol 0.1 Camphor 0.02 / 3-Glycyrrhizin 0.5 Ammonium Glycyrrhizin 0.00% 5 Pentthiophene methyl ether 1.0-D-Penthiphene methanol 1.0 Piroton • Olamine printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs 0.05 Pentaglycerol monomyristate 1.0 Sorbitol anhydride monolaurate 0.5 Sorbitol anhydride palmitate 2.0 Sodium lauryl sulfate 0.2 Lauryl dimethylamine aminated oxygen 0.1 42% Paper size Applicable to Chinese national standard (0 milk) 8 4 specifications (210 father 297 mm) 1232757 Α7 Β7 V. Invention Instructions (43) Decaglyceryl Myristate 0.5 Stearyl Trimethylammonium Chloride 0. 05 European Mint 0.5 (Please read the notes on the back before filling this page) Green Mint 0.5 Mint Plant Extract 1.0 p 1 ectranthus extract 0 · 5 osmoin extract · 1 Kirin vegetable extract 0.1 Sophora flavescens extract 0.1 Succinic acid 0.1 Aniline ammonium chloride 0.02 1-¾glyceryl ether 0.1 1-menthol 0.3 silicone emulsion (FZ-4672, by Made by Japan Unica Co.) 1.0 Liquid isolith 鱲 2.0 Propylene glycol 3.0 Isopropanol 5.0 Ethanol 3 0.0 Pure water printed by the Consumer Cooperative of the Intellectual Property Bureau of the Ministry of Economic Affairs ___ Balance of all 100.0% According to Example 1 above, evaluate the above implementation The stability of the formulations of Examples 19 to 39 in their individual outfit containers showed that all the stability was good. 421: This paper size applies to China National Standard (CNS) Α4 specification (210X297 mm)

Patent Application No. 121372_Amendment of Ming Dynasty July 1232757 ^ -r .. This, please -_ Eh. Issue · ί September 18, 91 Case No. 91121372 Category Na Ui, h and above Note from this Office) 1 A4 C4 g | Patent Specification Chinese Skin or Hair Treatment Composition Invention New Name English

Skin or hair treatment composition Name Nationality (1) Atsushi Yokomura (2) Ayano® (3) Ito Wuri (1) Invention and creation of No. 1-chome Sanban, Sumida Ward, Tokyo, Japan / (2) Tokyo, Japan Sumida Ward Office No. 1-chome Sanya No. 7 Residence and Residence (3) □ Honkuk Kyoto Sumida Ward Office 1-chome Sanfan No. t Name (Name) Nationality (1) Face Refinement Co., Ltd. Lost Talent > Co., Ltd. (!) Japanese version (1) □ Ben 0 Sumida ward office No. 1 Chome No. 3, Tokyo, applicant's residence, residence (office) Name of representative (1) Yoshida's pure paper size applies Chinese National Standards (CNS ) A4 size (210 X 297 mm) 1232757 Application date of September 18, 91 Case No. 91121372 Category (the above sheds are filled by this bureau)

Claims (1)

"23275 child A8 B8 C8 D8 VI. Patent application scope! n:, --...; Attachment 1 (A):, .. ........ ^ No. 9 1 1 2 1 3 No. 72 Chinese Patent Application Amendment Amendment July 16, 1993 1 · A skin or hair treatment composition, characterized in that it comprises a gallic acid derivative selected from the group consisting of the following formula (I): 0 / R1 0 ()) RH Please read the note above. Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs, where R1 represents hydrogen atom, alkali metal, alkaline earth metal, ammonium salt, or alkyl group with 1 to 6 carbon atoms; R2, R3 And R4 independently represents a hydrogen atom, a hydroxyl group, or a residue of a monosaccharide, a disaccharide, or an oligosaccharide; 90% by weight or more of one or more gallic acid derivatives (A) (wherein the formula (I) Two of R2, R3, and R4 in the above represent the residues of monosaccharides, disaccharides, or oligosaccharides); and 'derived from one or more gallic acids of 0.01% by weight to less than 10% by weight (B) (wherein one of R 2, R 3 and R 4 represents the residue of monosaccharide, disaccharide, or oligosaccharide), and each weight% is based on the total content of the gallic acid derivative. 2. The skin or hair treatment composition according to item 1 of the patent application scope, further comprising a cationic surfactant. 3. If the skin or hair treatment composition according to item 1 or 2 of the scope of patent application, it further comprises a xanthone compound. 4 · If the skin or hair of item 1 or 2 of the scope of patent application is applied. This paper size is applicable to China National Standard (CNS) A4 specification (210 X 297 mm) 1232757 A8 B8 C8 D8. A composition used as a hairdressing product. 5. The skin or hair treatment composition as claimed in claim 3, which is used as a hairdressing product. (Please read the notes on the back first, ¾ write this page). Binding and printing Printed by the Consumer Cooperatives of the Intellectual Property Bureau of the Ministry of Economic Affairs This paper size applies to China National Standard (CNS) A4 (210 X 297 mm)