TW450954B - Phenylsulfonamide-phenylethylamines useful as dopamine receptors - Google Patents

Phenylsulfonamide-phenylethylamines useful as dopamine receptors Download PDF

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Publication number
TW450954B
TW450954B TW088106644A TW88106644A TW450954B TW 450954 B TW450954 B TW 450954B TW 088106644 A TW088106644 A TW 088106644A TW 88106644 A TW88106644 A TW 88106644A TW 450954 B TW450954 B TW 450954B
Authority
TW
Taiwan
Prior art keywords
ethyl
patent application
propylamine
phenyl
compound
Prior art date
Application number
TW088106644A
Other languages
English (en)
Chinese (zh)
Inventor
Arthur Glenn Romero
Jeffrey A Leiby
Original Assignee
Pharmacia & Amp Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Amp Upjohn Company filed Critical Pharmacia & Amp Upjohn Company
Application granted granted Critical
Publication of TW450954B publication Critical patent/TW450954B/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW088106644A 1998-05-14 1999-04-26 Phenylsulfonamide-phenylethylamines useful as dopamine receptors TW450954B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8549398P 1998-05-14 1998-05-14

Publications (1)

Publication Number Publication Date
TW450954B true TW450954B (en) 2001-08-21

Family

ID=22191975

Family Applications (1)

Application Number Title Priority Date Filing Date
TW088106644A TW450954B (en) 1998-05-14 1999-04-26 Phenylsulfonamide-phenylethylamines useful as dopamine receptors

Country Status (24)

Country Link
US (1) US6103766A (https=)
EP (1) EP1077935B1 (https=)
JP (1) JP2002514623A (https=)
KR (1) KR20010043546A (https=)
CN (1) CN1152857C (https=)
AT (1) ATE253045T1 (https=)
AU (1) AU752543B2 (https=)
BR (1) BR9910405A (https=)
CA (1) CA2327345A1 (https=)
DE (1) DE69912419T2 (https=)
DK (1) DK1077935T3 (https=)
EA (1) EA002918B1 (https=)
ES (1) ES2211078T3 (https=)
HU (1) HUP0101746A3 (https=)
IL (1) IL139263A0 (https=)
NO (1) NO20005732L (https=)
NZ (1) NZ508152A (https=)
PL (1) PL343891A1 (https=)
PT (1) PT1077935E (https=)
SK (1) SK16242000A3 (https=)
TR (1) TR200003325T2 (https=)
TW (1) TW450954B (https=)
WO (1) WO1999058499A1 (https=)
ZA (1) ZA200005921B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2300119T3 (es) * 1997-02-27 2008-06-01 Takeda Pharmaceutical Company Limited Compuestos de amina, su produccion y su uso como inhibidores de la produccion de beta-amiloide.
WO2002089785A1 (en) * 2001-05-07 2002-11-14 Smithkline Beecham Corporation Sulfonamides
WO2002089740A2 (en) * 2001-05-07 2002-11-14 Smithkline Beecham Corporation Sulfonamides
EP1812389B1 (en) 2004-10-14 2011-08-17 Abbott GmbH & Co. KG Azabicycloheptyl compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
CA2583983C (en) 2004-10-14 2013-07-16 Abbott Gmbh & Co. Kg Heterocyclic compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
ATE540922T1 (de) 2004-10-14 2012-01-15 Abbott Gmbh & Co Kg Zur behandlung von erkrankungen, die auf eine modulation des dopamin-d3-rezeptors ansprechen, geeignete aminoethylaromatische verbindungen
ATE496031T1 (de) * 2006-04-14 2011-02-15 Abbott Gmbh & Co Kg Für die behandlung von auf die modulierung des dopamin-d3-rezeptors ansprechende erkrankungen geeignete aryloxyethylaminverbindungen
AR060462A1 (es) 2006-04-14 2008-06-18 Abbott Gmbh & Co Kg Compuestos de ariloxietilamina apropiados para tratar trastornos que responden a la modulacion del receptor de dopamina d3
BRPI0710177A2 (pt) 2006-04-19 2012-05-29 Abbott Gmbh & Co Kg arilsulfonas heterocìclicas adequadas para tratar distúrbios que respondem à modulação do receptor 5ht6 de serotonina
WO2007118900A1 (en) 2006-04-19 2007-10-25 Abbott Gmbh & Co. Kg Heterocyclic compounds suitable for treating disorders that respond to modulation of the serotonin 5ht6 receptor
WO2008026046A1 (en) * 2006-08-30 2008-03-06 Pfizer Products Inc. Morpholine d3 dopamine antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9402197D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Compounds
EP0793653A1 (en) * 1994-11-23 1997-09-10 Neurogen Corporation Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands
WO1997043262A1 (en) * 1996-05-11 1997-11-20 Smithkline Beecham P.L.C. Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
US5922770A (en) * 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
JPH1180156A (ja) * 1997-09-04 1999-03-26 Hokuriku Seiyaku Co Ltd 1−(置換アリール)アルキル−1h−イミダゾピリジン−4−アミン誘導体

Also Published As

Publication number Publication date
CN1297431A (zh) 2001-05-30
NZ508152A (en) 2003-03-28
US6103766A (en) 2000-08-15
WO1999058499A1 (en) 1999-11-18
BR9910405A (pt) 2001-01-09
DE69912419D1 (de) 2003-12-04
IL139263A0 (en) 2001-11-25
CA2327345A1 (en) 1999-11-18
HK1036049A1 (en) 2001-12-21
EA200001184A1 (ru) 2001-04-23
ZA200005921B (en) 2001-11-14
AU3741899A (en) 1999-11-29
PT1077935E (pt) 2004-03-31
NO20005732D0 (no) 2000-11-13
EP1077935B1 (en) 2003-10-29
EA002918B1 (ru) 2002-10-31
SK16242000A3 (sk) 2001-06-11
HUP0101746A3 (en) 2002-10-28
HUP0101746A2 (hu) 2002-03-28
PL343891A1 (en) 2001-09-10
DE69912419T2 (de) 2004-07-22
DK1077935T3 (da) 2004-02-16
ES2211078T3 (es) 2004-07-01
JP2002514623A (ja) 2002-05-21
CN1152857C (zh) 2004-06-09
ATE253045T1 (de) 2003-11-15
TR200003325T2 (tr) 2001-04-20
AU752543B2 (en) 2002-09-19
NO20005732L (no) 2000-11-13
KR20010043546A (ko) 2001-05-25
EP1077935A1 (en) 2001-02-28

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