TW427986B - 4-amino 6-substituted mycophenolic acid and derivatives - Google Patents
4-amino 6-substituted mycophenolic acid and derivativesInfo
- Publication number
- TW427986B TW427986B TW084101399A TW84101399A TW427986B TW 427986 B TW427986 B TW 427986B TW 084101399 A TW084101399 A TW 084101399A TW 84101399 A TW84101399 A TW 84101399A TW 427986 B TW427986 B TW 427986B
- Authority
- TW
- Taiwan
- Prior art keywords
- mycophenolic acid
- derivatives
- amino
- substituted mycophenolic
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/198,741 US5525602A (en) | 1994-02-18 | 1994-02-18 | Method of using 4-amino 6-substituted mycophenolic acid and derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
TW427986B true TW427986B (en) | 2001-04-01 |
Family
ID=22734615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW084101399A TW427986B (en) | 1994-02-18 | 1995-02-16 | 4-amino 6-substituted mycophenolic acid and derivatives |
Country Status (19)
Country | Link |
---|---|
US (2) | US5525602A (zh) |
EP (1) | EP0745071B1 (zh) |
JP (1) | JPH09509170A (zh) |
CN (1) | CN1141632A (zh) |
AT (1) | ATE210126T1 (zh) |
AU (1) | AU1747295A (zh) |
BR (1) | BR9506836A (zh) |
CA (1) | CA2183532A1 (zh) |
CO (1) | CO4340733A1 (zh) |
DE (1) | DE69524388T2 (zh) |
DK (1) | DK0745071T3 (zh) |
ES (1) | ES2169124T3 (zh) |
FI (1) | FI963222A (zh) |
IL (1) | IL112668A (zh) |
MX (1) | MX9603477A (zh) |
PT (1) | PT745071E (zh) |
TW (1) | TW427986B (zh) |
WO (1) | WO1995022534A1 (zh) |
ZA (1) | ZA951300B (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19541578C2 (de) * | 1995-11-08 | 1997-08-21 | Koenig & Bauer Albert Ag | Wendestange |
US6514979B1 (en) | 1999-03-03 | 2003-02-04 | University Of Maryland Biotechnology Institute | Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor |
US6811998B2 (en) * | 1999-06-25 | 2004-11-02 | Roche Diagnostics Operations, Inc. | Conjugates of uncompetitive inhibitors of inosine monophosphate dehydrogenase |
US20050187170A1 (en) * | 2003-06-16 | 2005-08-25 | Biocryst Pharmaceuticals, Inc. | Enhancing the efficiency of RNA polymerase inhibitors by using inosine monophosphate dehydrogenase inhibitors |
CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
US10603299B2 (en) | 2016-06-02 | 2020-03-31 | Steven Baranowitz | Prevention and treatment of viral infections |
CA3026241A1 (en) | 2016-06-02 | 2017-12-07 | Steven Baranowitz | Prevention and treatment of viral infections |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3825571A (en) * | 1971-07-31 | 1974-07-23 | Chugai Pharmaceutical Co Ltd | Mycophenolic acid derivatives |
JPS5542995B2 (zh) * | 1972-02-24 | 1980-11-04 | ||
JPS5529994B2 (zh) * | 1972-03-02 | 1980-08-07 | ||
US4686234A (en) * | 1985-11-27 | 1987-08-11 | Syntex (U.S.A) Inc. | Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis |
US4959387A (en) * | 1986-01-23 | 1990-09-25 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
US4725622A (en) * | 1986-01-23 | 1988-02-16 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
US4861776A (en) * | 1987-01-30 | 1989-08-29 | Syntex (U.S.A) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof, compositions and use |
US4727069A (en) * | 1987-01-30 | 1988-02-23 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid, derivatives thereof and pharmaceutical compositions |
US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
US4748173A (en) * | 1987-01-30 | 1988-05-31 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions |
JPH0637486B2 (ja) * | 1988-05-18 | 1994-05-18 | 三共株式会社 | 新規抗生物質フタレキシンおよびその製造法 |
US5247083A (en) * | 1992-07-10 | 1993-09-21 | Syntex (U.S.A.) Inc. | Direct esterification of mycophenolic acid |
US5380879A (en) * | 1994-02-18 | 1995-01-10 | Syntex (U.S.A.) Inc. | Derivatives of mycophenolic acid |
-
1994
- 1994-02-18 US US08/198,741 patent/US5525602A/en not_active Expired - Fee Related
-
1995
- 1995-02-16 DK DK95909544T patent/DK0745071T3/da active
- 1995-02-16 ES ES95909544T patent/ES2169124T3/es not_active Expired - Lifetime
- 1995-02-16 MX MX9603477A patent/MX9603477A/es unknown
- 1995-02-16 JP JP7521864A patent/JPH09509170A/ja not_active Ceased
- 1995-02-16 CN CN95191712A patent/CN1141632A/zh active Pending
- 1995-02-16 WO PCT/US1995/001783 patent/WO1995022534A1/en active IP Right Grant
- 1995-02-16 PT PT95909544T patent/PT745071E/pt unknown
- 1995-02-16 IL IL11266895A patent/IL112668A/xx not_active IP Right Cessation
- 1995-02-16 EP EP95909544A patent/EP0745071B1/en not_active Expired - Lifetime
- 1995-02-16 DE DE69524388T patent/DE69524388T2/de not_active Expired - Fee Related
- 1995-02-16 AT AT95909544T patent/ATE210126T1/de not_active IP Right Cessation
- 1995-02-16 ZA ZA951300A patent/ZA951300B/xx unknown
- 1995-02-16 CA CA002183532A patent/CA2183532A1/en not_active Abandoned
- 1995-02-16 AU AU17472/95A patent/AU1747295A/en not_active Abandoned
- 1995-02-16 CO CO95005928A patent/CO4340733A1/es unknown
- 1995-02-16 BR BR9506836A patent/BR9506836A/pt not_active Application Discontinuation
- 1995-02-16 TW TW084101399A patent/TW427986B/zh not_active IP Right Cessation
- 1995-05-26 US US08/452,243 patent/US5554612A/en not_active Expired - Fee Related
-
1996
- 1996-08-16 FI FI963222A patent/FI963222A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
IL112668A (en) | 1999-08-17 |
IL112668A0 (en) | 1995-05-26 |
DK0745071T3 (da) | 2002-04-02 |
WO1995022534A1 (en) | 1995-08-24 |
EP0745071B1 (en) | 2001-12-05 |
DE69524388T2 (de) | 2002-08-14 |
MX9603477A (es) | 1997-12-31 |
DE69524388D1 (de) | 2002-01-17 |
AU1747295A (en) | 1995-09-04 |
US5554612A (en) | 1996-09-10 |
PT745071E (pt) | 2002-04-29 |
FI963222A (fi) | 1996-10-18 |
ES2169124T3 (es) | 2002-07-01 |
FI963222A0 (fi) | 1996-08-16 |
CA2183532A1 (en) | 1995-08-24 |
CO4340733A1 (es) | 1996-07-30 |
EP0745071A1 (en) | 1996-12-04 |
CN1141632A (zh) | 1997-01-29 |
JPH09509170A (ja) | 1997-09-16 |
ATE210126T1 (de) | 2001-12-15 |
BR9506836A (pt) | 1997-10-14 |
ZA951300B (en) | 1996-08-16 |
US5525602A (en) | 1996-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GD4A | Issue of patent certificate for granted invention patent | ||
MM4A | Annulment or lapse of patent due to non-payment of fees |