|
RU2127274C1
(ru)
*
|
1992-09-25 |
1999-03-10 |
Эли Лилли Энд Компани |
СПОСОБ ПОЛУЧЕНИЯ 5-ЗАМЕЩЕННЫХ ПИРРОЛО (2,3-α)ПИРИМИДИНОВ
|
|
US7863444B2
(en)
|
1997-03-19 |
2011-01-04 |
Abbott Laboratories |
4-aminopyrrolopyrimidines as kinase inhibitors
|
|
IL135190A
(en)
*
|
1997-09-26 |
2005-03-20 |
Lilly Co Eli |
Processes and intermediates useful to make antifolates
|
|
ZA987550B
(en)
*
|
1997-09-26 |
2000-02-21 |
Lilly Co Eli |
Processes and intermediates useful to make antifolates.
|
|
US6713474B2
(en)
|
1998-09-18 |
2004-03-30 |
Abbott Gmbh & Co. Kg |
Pyrrolopyrimidines as therapeutic agents
|
|
US7071199B1
(en)
|
1999-09-17 |
2006-07-04 |
Abbott Gmbh & Cco. Kg |
Kinase inhibitors as therapeutic agents
|
|
US7138521B2
(en)
*
|
2000-02-25 |
2006-11-21 |
Eli Lilly And Company |
Crystalline of N-[4-[2-(2-Amino-4,7-dihydro-4oxo-3H-pyrrolo[2,3-D]pyrimidin-5-YL)ethyl]benzoyl]-L-glutamic acid and process therefor
|
|
KR101083230B1
(ko)
*
|
2006-08-14 |
2011-11-11 |
시코르, 인크. |
페메트렉세드 이산의 동결 건조된 약학적 허용염의 제조 방법
|
|
JP2008543974A
(ja)
*
|
2006-08-14 |
2008-12-04 |
シコール インコーポレイティド |
ペメトレキセド二酸の結晶形およびその調製方法
|
|
EP1934226A2
(en)
*
|
2006-08-14 |
2008-06-25 |
Sicor, Inc. |
Highly pure pemetrexed diacid and processes for the preparation thereof
|
|
US7994180B2
(en)
*
|
2006-08-14 |
2011-08-09 |
Sicor Inc. |
Processes for preparing intermediates of pemetrexed
|
|
EP2129674A2
(en)
*
|
2007-04-03 |
2009-12-09 |
Dr. Reddy's Laboratories Ltd. |
Solid forms of pemetrexed
|
|
US8232376B2
(en)
|
2007-06-29 |
2012-07-31 |
Ricoh Company, Ltd. |
Azo compound and method of preparing the azo compound
|
|
US20090069349A1
(en)
*
|
2007-09-12 |
2009-03-12 |
Protia, Llc |
Deuterium-enriched pemetrexed
|
|
CN101684121B
(zh)
*
|
2008-09-22 |
2013-04-03 |
重庆医药工业研究院有限责任公司 |
培美曲塞二酸的新晶型及其制备方法
|
|
TW201118098A
(en)
*
|
2009-08-13 |
2011-06-01 |
Reddy S Lab Liimited Dr |
Processes for preparing pemetrexed
|
|
JP2013531067A
(ja)
|
2010-07-19 |
2013-08-01 |
バイエル ヘルスケア リミティド ライアビリティ カンパニー |
疾病及び状態の処置及び予防のためのフルオロ置換オメガ−カルボキシアリールジフェニル尿素を用いた組み合わせ薬
|
|
IT1401677B1
(it)
|
2010-07-22 |
2013-08-02 |
Chemi Spa |
Nuovo processo per la sintesi di pemetrexed sale disodico
|
|
CN102372719B
(zh)
*
|
2010-08-26 |
2013-10-30 |
齐鲁制药有限公司 |
培美曲塞二甲酯对甲苯磺酸盐晶型及其制备方法
|
|
WO2012056285A1
(en)
|
2010-10-25 |
2012-05-03 |
Fresenius Kabi Oncology Ltd. |
An improved process for the preparation of pemetrexed
|
|
KR101308767B1
(ko)
|
2011-01-20 |
2013-12-31 |
에스티팜 주식회사 |
고 순도 페메트렉세드 디에틸 에스테르의 제조방법 및 이 방법을 포함하는 페메트렉세드 이나트륨염의 제조방법
|
|
ITRM20120398A1
(it)
|
2012-08-08 |
2014-02-09 |
Berlin Chemie Ag |
Procedimento di sintesi pemetrexed e suo sale di lisina.
|
|
CN102887902B
(zh)
*
|
2012-10-10 |
2015-05-20 |
北京莱瑞森医药科技有限公司 |
一种合成高纯度培美酸的制备工艺
|
|
CN103086912A
(zh)
*
|
2012-11-14 |
2013-05-08 |
湖北一半天制药有限公司 |
用于制备培美曲塞及其中间体的方法
|
|
EP3308770A1
(en)
|
2013-04-12 |
2018-04-18 |
Actavis Group PTC EHF |
Pemetrexed formulation
|
|
US20160145260A1
(en)
|
2013-06-14 |
2016-05-26 |
Synthon B.V. |
Stable pemetrexed arginine salt and compositions comprising it
|
|
CN107628947B
(zh)
*
|
2017-09-14 |
2020-07-28 |
浙江工业大学 |
一种培美曲塞二钠关键中间体的制备方法
|
|
JP7490239B2
(ja)
|
2018-02-07 |
2024-05-27 |
エル．イー．エー．エフ． ホールディングス グループ エルエルシー |
ガンマポリグルタミン酸化ペメトレキセドおよびその使用
|
|
EP3749317A4
(en)
|
2018-02-07 |
2022-06-22 |
L.E.A.F Holdings Group LLC |
PEMETREXED ALPHA-POLYGLUTAMATE AND ASSOCIATED USES
|
|
WO2020222151A1
(en)
|
2019-05-01 |
2020-11-05 |
Intas Pharmaceuticals Ltd. |
A stable, ready to use aqueous pharmaceutical composition of pemetrexed
|