TW224466B - - Google Patents

Info

Publication number
TW224466B
TW224466B TW082101219A TW82101219A TW224466B TW 224466 B TW224466 B TW 224466B TW 082101219 A TW082101219 A TW 082101219A TW 82101219 A TW82101219 A TW 82101219A TW 224466 B TW224466 B TW 224466B
Authority
TW
Taiwan
Prior art keywords
formula
compounds
chem
nitrosating
pharmaceutical activity
Prior art date
Application number
TW082101219A
Other languages
English (en)
Chinese (zh)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of TW224466B publication Critical patent/TW224466B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW082101219A 1992-02-20 1993-02-22 TW224466B (en, 2012)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929203688A GB9203688D0 (en) 1992-02-20 1992-02-20 Novel process

Publications (1)

Publication Number Publication Date
TW224466B true TW224466B (en, 2012) 1994-06-01

Family

ID=10710781

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082101219A TW224466B (en, 2012) 1992-02-20 1993-02-22

Country Status (18)

Country Link
US (2) US5545740A (en, 2012)
EP (2) EP0984008A3 (en, 2012)
JP (1) JP3288704B2 (en, 2012)
KR (1) KR100261530B1 (en, 2012)
AT (1) ATE194341T1 (en, 2012)
AU (1) AU669355B2 (en, 2012)
CA (1) CA2131019C (en, 2012)
DE (1) DE69328962T2 (en, 2012)
DK (1) DK0626961T3 (en, 2012)
ES (1) ES2147749T3 (en, 2012)
GB (1) GB9203688D0 (en, 2012)
GR (1) GR3034295T3 (en, 2012)
MX (1) MX9300875A (en, 2012)
NZ (1) NZ246940A (en, 2012)
PT (1) PT626961E (en, 2012)
TW (1) TW224466B (en, 2012)
WO (1) WO1993017018A1 (en, 2012)
ZA (1) ZA931132B (en, 2012)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9300875A (es) 1992-02-20 1993-08-31 Smithkline Beecham Plc Procedimiento para la preparacion de compuestos azabiciclicos.
GB9409705D0 (en) * 1994-05-14 1994-07-06 Smithkline Beecham Plc Novel compounds
GB9421472D0 (en) * 1994-10-25 1994-12-07 Smithkline Beecham Plc Novel methods
GB9615628D0 (en) * 1996-07-25 1996-09-04 Smithkline Beecham Plc Formulation
EP1009403A4 (en) * 1997-04-11 2002-08-28 Lilly Co Eli METHOD FOR TREATING SCHIZOPHRENIA
JP2002503224A (ja) * 1997-04-11 2002-01-29 エリ リリー アンド カンパニー 疼痛を処置するための組成物
US7678363B2 (en) * 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1600969A (en) 1977-01-07 1981-10-21 Acf Chemiefarma Nv Heterocyclic compounds
US4937239A (en) * 1989-02-13 1990-06-26 Warner-Lambert Company Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
US5418240A (en) 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
MX9300875A (es) 1992-02-20 1993-08-31 Smithkline Beecham Plc Procedimiento para la preparacion de compuestos azabiciclicos.

Also Published As

Publication number Publication date
WO1993017018A1 (en) 1993-09-02
EP0626961A1 (en) 1994-12-07
PT626961E (pt) 2000-10-31
AU3460793A (en) 1993-09-13
ES2147749T3 (es) 2000-10-01
CA2131019C (en) 2002-12-24
EP0984008A3 (en) 2000-05-03
EP0626961B1 (en) 2000-07-05
ATE194341T1 (de) 2000-07-15
DE69328962T2 (de) 2000-12-28
HK1012366A1 (en) 1999-07-30
GB9203688D0 (en) 1992-04-08
EP0984008A2 (en) 2000-03-08
JPH07504180A (ja) 1995-05-11
JP3288704B2 (ja) 2002-06-04
NZ246940A (en) 1996-06-25
DK0626961T3 (da) 2000-11-06
MX9300875A (es) 1993-08-31
DE69328962D1 (de) 2000-08-10
US6596869B2 (en) 2003-07-22
AU669355B2 (en) 1996-06-06
KR950700292A (ko) 1995-01-16
CA2131019A1 (en) 1993-08-21
KR100261530B1 (ko) 2000-08-01
US20020143185A1 (en) 2002-10-03
GR3034295T3 (en) 2000-12-29
ZA931132B (en) 1993-10-14
US5545740A (en) 1996-08-13

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