TW224094B - - Google Patents

Info

Publication number
TW224094B
TW224094B TW082100795A TW82100795A TW224094B TW 224094 B TW224094 B TW 224094B TW 082100795 A TW082100795 A TW 082100795A TW 82100795 A TW82100795 A TW 82100795A TW 224094 B TW224094 B TW 224094B
Authority
TW
Taiwan
Prior art keywords
alkyl
sulphinyl
sulphonyl
alkylamino
thio
Prior art date
Application number
TW082100795A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Zineka Famo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Zineka Famo Co filed Critical Zeneca Ltd
Application granted granted Critical
Publication of TW224094B publication Critical patent/TW224094B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Furan Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW082100795A 1992-02-07 1993-02-05 TW224094B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92400318 1992-02-07
EP92402764 1992-10-09
GB939300894A GB9300894D0 (en) 1992-02-07 1993-01-18 Oxime derivatives

Publications (1)

Publication Number Publication Date
TW224094B true TW224094B (zh) 1994-05-21

Family

ID=26132332

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082100795A TW224094B (zh) 1992-02-07 1993-02-05

Country Status (20)

Country Link
US (2) US5332757A (zh)
EP (1) EP0555068B1 (zh)
JP (1) JPH05286957A (zh)
AT (1) ATE136546T1 (zh)
AU (1) AU658964B2 (zh)
CA (1) CA2088864A1 (zh)
CZ (1) CZ13393A3 (zh)
DE (1) DE69302109T2 (zh)
ES (1) ES2086878T3 (zh)
FI (1) FI930475A (zh)
GB (1) GB9300894D0 (zh)
GR (1) GR3019634T3 (zh)
HU (1) HUT63840A (zh)
IL (1) IL104624A0 (zh)
NO (1) NO930411L (zh)
NZ (1) NZ245772A (zh)
PL (1) PL297666A1 (zh)
SK (1) SK6993A3 (zh)
TW (1) TW224094B (zh)
ZW (1) ZW1293A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL108187A0 (en) * 1993-01-28 1994-04-12 Zenecca Limited Oxime derivatives
ZA945250B (en) * 1993-07-27 1995-01-27 Zeneca Ltd Thiazole derivatives
WO1995030668A1 (en) * 1994-05-06 1995-11-16 Zeneca Limited Cyclic ether derivatives and pharmaceutical composition containing them
US5668159A (en) * 1996-05-08 1997-09-16 The Dupont Merck Pharmaceutical Company 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists
KR20000067915A (ko) 1996-07-19 2000-11-25 센토르 파마슈티칼스, 인크. 푸란 니트론 화합물
ATE228123T1 (de) * 1998-01-16 2002-12-15 Centaur Pharmaceuticals Inc Thiophennitronderivate
CN1291980A (zh) * 1998-01-16 2001-04-18 桑道药品有限公司 硫醚呋喃硝酮化合物
WO2004108720A1 (en) * 2003-06-11 2004-12-16 Merck Frosst Canada Ltd. 7- (1, 3-thiazol-2-yl)thio!-coumarin derivatives and their use as leukotriene biosynthesis inhibitors
WO2009069044A1 (en) * 2007-11-26 2009-06-04 Pfizer Inc. Pyrazole derivatives as 5-lo inhibitors
CN104447658A (zh) * 2014-12-04 2015-03-25 杭州杜易科技有限公司 一种卤代4-色满酮衍生物的制备方法
EP3601267A1 (en) 2017-03-21 2020-02-05 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
WO2019201848A1 (en) 2018-04-18 2019-10-24 Bayer Pharma Aktiengesellschaft 2-methyl-aza-quinazolines
BR112021008900A2 (pt) * 2018-11-08 2021-08-10 Unilever Ip Holdings B.V. processo para a síntese de lactama
EP3880758B1 (en) * 2018-11-08 2024-06-26 Unilever Global Ip Limited Method of treatment of a surface
JPWO2020250880A1 (zh) * 2019-06-11 2020-12-17

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4567184A (en) * 1982-12-01 1986-01-28 Usv Pharmaceutical Corporation Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
US4794188A (en) * 1982-12-01 1988-12-27 Usv Pharmaceutical Corporation Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4625034A (en) * 1985-02-04 1986-11-25 Usv Pharmaceutical Corp. 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives
US4661596A (en) * 1985-02-21 1987-04-28 American Home Products Corporation Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
DE3617183A1 (de) * 1985-11-16 1987-05-27 Bayer Ag Substituierte benzylether
US4681940A (en) * 1985-11-19 1987-07-21 American Home Products Corporation 5-[3-[[2-quinolyl]methoxy]phenyl]-1,3-oxazoles
US4868193A (en) * 1986-09-24 1989-09-19 Rorer Pharmaceutical Corporation Styryl tetrazoles and anti-allergic use thereof
GB8927287D0 (en) * 1988-12-23 1990-01-31 Ici Plc Cyclic ether derivatives
IL92620A0 (en) * 1988-12-23 1990-08-31 Ici Pharma Cycloalkane derivatives
GB8926981D0 (en) * 1988-12-23 1990-01-17 Ici Plc Heterocyclic derivatives
IL93344A0 (en) * 1989-02-28 1990-11-29 Ici Plc Heterocyclic cyclic ethers
US5134148A (en) * 1989-02-28 1992-07-28 Imperial Chemical Industries Plc Heterocycles for use as inhibitors of leukotrienes
IE70521B1 (en) * 1989-02-28 1996-12-11 Zeneca Pharma Sa Heterocycles with inhibitory activity of 5-lipoxygenase
IE902113A1 (en) * 1989-07-18 1991-06-19 Ici Plc Diaryl ether cyclic ethers
IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles
ES2083526T3 (es) * 1990-06-21 1996-04-16 Zeneca Ltd Derivados piranicos biciclicos y su uso como inhibidores de 5-lipoxigenasa.
IE911853A1 (en) * 1990-06-21 1992-01-01 Ici Plc Heterocyclene derivatives
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives

Also Published As

Publication number Publication date
US5482966A (en) 1996-01-09
EP0555068A1 (en) 1993-08-11
AU3197293A (en) 1993-08-12
FI930475A (fi) 1993-08-08
HU9300272D0 (en) 1993-04-28
AU658964B2 (en) 1995-05-04
NZ245772A (en) 1995-05-26
NO930411D0 (no) 1993-02-05
PL297666A1 (en) 1993-10-18
IL104624A0 (en) 1993-06-10
DE69302109D1 (de) 1996-05-15
JPH05286957A (ja) 1993-11-02
HUT63840A (en) 1993-10-28
CZ13393A3 (en) 1993-10-13
ATE136546T1 (de) 1996-04-15
NO930411L (no) 1993-08-09
US5332757A (en) 1994-07-26
ES2086878T3 (es) 1996-07-01
GB9300894D0 (en) 1993-03-10
EP0555068B1 (en) 1996-04-10
GR3019634T3 (en) 1996-07-31
ZW1293A1 (en) 1993-09-29
SK6993A3 (en) 1993-09-09
FI930475A0 (fi) 1993-02-03
CA2088864A1 (en) 1993-08-08
DE69302109T2 (de) 1996-10-17

Similar Documents

Publication Publication Date Title
TW224094B (zh)
HUT61999A (en) Process for producing thioxo compounds and pharmaceutical compositions comprising same as active ingredient
IL109615A0 (en) Polypeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL94732A0 (en) Heterocyclic diaryl ethers,process for their preparation and pharmaceutical compositions containing them
MY106366A (en) Bicyclic heterocyclic pryan derivatives and their use as inhibitors of 5-lipoxygenase
GB2264946B (en) Anti-tumour compounds
DE3360589D1 (en) 4"-epi erythromycin a and derivatives thereof as useful antibacterial agents
EP0670317A4 (zh)
DE69003616D1 (en) Diarylcycloalkanether.