SK6993A3 - Oxime derivatives, process for their manufacture, pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors - Google Patents
Oxime derivatives, process for their manufacture, pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors Download PDFInfo
- Publication number
- SK6993A3 SK6993A3 SK6993A SK6993A SK6993A3 SK 6993 A3 SK6993 A3 SK 6993A3 SK 6993 A SK6993 A SK 6993A SK 6993 A SK6993 A SK 6993A SK 6993 A3 SK6993 A3 SK 6993A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- carbon atoms
- alkyl
- methoxy
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Peptides Or Proteins (AREA)
- Furan Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92400318 | 1992-02-07 | ||
EP92402764 | 1992-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
SK6993A3 true SK6993A3 (en) | 1993-09-09 |
Family
ID=26132332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK6993A SK6993A3 (en) | 1992-02-07 | 1993-02-05 | Oxime derivatives, process for their manufacture, pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors |
Country Status (20)
Country | Link |
---|---|
US (2) | US5332757A (zh) |
EP (1) | EP0555068B1 (zh) |
JP (1) | JPH05286957A (zh) |
AT (1) | ATE136546T1 (zh) |
AU (1) | AU658964B2 (zh) |
CA (1) | CA2088864A1 (zh) |
CZ (1) | CZ13393A3 (zh) |
DE (1) | DE69302109T2 (zh) |
ES (1) | ES2086878T3 (zh) |
FI (1) | FI930475A (zh) |
GB (1) | GB9300894D0 (zh) |
GR (1) | GR3019634T3 (zh) |
HU (1) | HUT63840A (zh) |
IL (1) | IL104624A0 (zh) |
NO (1) | NO930411L (zh) |
NZ (1) | NZ245772A (zh) |
PL (1) | PL297666A1 (zh) |
SK (1) | SK6993A3 (zh) |
TW (1) | TW224094B (zh) |
ZW (1) | ZW1293A1 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL108187A0 (en) * | 1993-01-28 | 1994-04-12 | Zenecca Limited | Oxime derivatives |
ZA945250B (en) * | 1993-07-27 | 1995-01-27 | Zeneca Ltd | Thiazole derivatives |
WO1995030668A1 (en) * | 1994-05-06 | 1995-11-16 | Zeneca Limited | Cyclic ether derivatives and pharmaceutical composition containing them |
US5668159A (en) * | 1996-05-08 | 1997-09-16 | The Dupont Merck Pharmaceutical Company | 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists |
KR20000067915A (ko) | 1996-07-19 | 2000-11-25 | 센토르 파마슈티칼스, 인크. | 푸란 니트론 화합물 |
ATE228123T1 (de) * | 1998-01-16 | 2002-12-15 | Centaur Pharmaceuticals Inc | Thiophennitronderivate |
CN1291980A (zh) * | 1998-01-16 | 2001-04-18 | 桑道药品有限公司 | 硫醚呋喃硝酮化合物 |
WO2004108720A1 (en) * | 2003-06-11 | 2004-12-16 | Merck Frosst Canada Ltd. | 7- (1, 3-thiazol-2-yl)thio!-coumarin derivatives and their use as leukotriene biosynthesis inhibitors |
WO2009069044A1 (en) * | 2007-11-26 | 2009-06-04 | Pfizer Inc. | Pyrazole derivatives as 5-lo inhibitors |
CN104447658A (zh) * | 2014-12-04 | 2015-03-25 | 杭州杜易科技有限公司 | 一种卤代4-色满酮衍生物的制备方法 |
EP3601267A1 (en) | 2017-03-21 | 2020-02-05 | Bayer Pharma Aktiengesellschaft | 2-methyl-quinazolines |
WO2019201848A1 (en) | 2018-04-18 | 2019-10-24 | Bayer Pharma Aktiengesellschaft | 2-methyl-aza-quinazolines |
BR112021008900A2 (pt) * | 2018-11-08 | 2021-08-10 | Unilever Ip Holdings B.V. | processo para a síntese de lactama |
EP3880758B1 (en) * | 2018-11-08 | 2024-06-26 | Unilever Global Ip Limited | Method of treatment of a surface |
JPWO2020250880A1 (zh) * | 2019-06-11 | 2020-12-17 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
US4567184A (en) * | 1982-12-01 | 1986-01-28 | Usv Pharmaceutical Corporation | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies |
US4794188A (en) * | 1982-12-01 | 1988-12-27 | Usv Pharmaceutical Corporation | Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity |
NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
US4625034A (en) * | 1985-02-04 | 1986-11-25 | Usv Pharmaceutical Corp. | 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives |
US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4728668A (en) * | 1985-04-16 | 1988-03-01 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4725619A (en) * | 1985-04-16 | 1988-02-16 | Usv Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
US4876346A (en) * | 1985-05-02 | 1989-10-24 | American Home Products Corporation | Quinoline compounds |
DE3617183A1 (de) * | 1985-11-16 | 1987-05-27 | Bayer Ag | Substituierte benzylether |
US4681940A (en) * | 1985-11-19 | 1987-07-21 | American Home Products Corporation | 5-[3-[[2-quinolyl]methoxy]phenyl]-1,3-oxazoles |
US4868193A (en) * | 1986-09-24 | 1989-09-19 | Rorer Pharmaceutical Corporation | Styryl tetrazoles and anti-allergic use thereof |
GB8927287D0 (en) * | 1988-12-23 | 1990-01-31 | Ici Plc | Cyclic ether derivatives |
IL92620A0 (en) * | 1988-12-23 | 1990-08-31 | Ici Pharma | Cycloalkane derivatives |
GB8926981D0 (en) * | 1988-12-23 | 1990-01-17 | Ici Plc | Heterocyclic derivatives |
IL93344A0 (en) * | 1989-02-28 | 1990-11-29 | Ici Plc | Heterocyclic cyclic ethers |
US5134148A (en) * | 1989-02-28 | 1992-07-28 | Imperial Chemical Industries Plc | Heterocycles for use as inhibitors of leukotrienes |
IE70521B1 (en) * | 1989-02-28 | 1996-12-11 | Zeneca Pharma Sa | Heterocycles with inhibitory activity of 5-lipoxygenase |
IE902113A1 (en) * | 1989-07-18 | 1991-06-19 | Ici Plc | Diaryl ether cyclic ethers |
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
ES2083526T3 (es) * | 1990-06-21 | 1996-04-16 | Zeneca Ltd | Derivados piranicos biciclicos y su uso como inhibidores de 5-lipoxigenasa. |
IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
-
1993
- 1993-01-18 GB GB939300894A patent/GB9300894D0/en active Pending
- 1993-01-21 ZW ZW12/93A patent/ZW1293A1/xx unknown
- 1993-01-22 AU AU31972/93A patent/AU658964B2/en not_active Ceased
- 1993-01-27 NZ NZ245772A patent/NZ245772A/en unknown
- 1993-02-03 AT AT93300782T patent/ATE136546T1/de not_active IP Right Cessation
- 1993-02-03 ES ES93300782T patent/ES2086878T3/es not_active Expired - Lifetime
- 1993-02-03 DE DE69302109T patent/DE69302109T2/de not_active Expired - Fee Related
- 1993-02-03 HU HU9300272A patent/HUT63840A/hu unknown
- 1993-02-03 EP EP93300782A patent/EP0555068B1/en not_active Expired - Lifetime
- 1993-02-03 FI FI930475A patent/FI930475A/fi not_active Application Discontinuation
- 1993-02-04 IL IL104624A patent/IL104624A0/xx unknown
- 1993-02-04 CZ CZ93133A patent/CZ13393A3/cs unknown
- 1993-02-05 TW TW082100795A patent/TW224094B/zh active
- 1993-02-05 SK SK6993A patent/SK6993A3/sk unknown
- 1993-02-05 PL PL29766693A patent/PL297666A1/xx unknown
- 1993-02-05 CA CA002088864A patent/CA2088864A1/en not_active Abandoned
- 1993-02-05 NO NO93930411A patent/NO930411L/no unknown
- 1993-02-05 JP JP5018574A patent/JPH05286957A/ja active Pending
- 1993-02-08 US US08/014,564 patent/US5332757A/en not_active Expired - Fee Related
-
1994
- 1994-06-13 US US08/240,464 patent/US5482966A/en not_active Expired - Fee Related
-
1996
- 1996-04-11 GR GR960400829T patent/GR3019634T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5482966A (en) | 1996-01-09 |
EP0555068A1 (en) | 1993-08-11 |
AU3197293A (en) | 1993-08-12 |
FI930475A (fi) | 1993-08-08 |
HU9300272D0 (en) | 1993-04-28 |
AU658964B2 (en) | 1995-05-04 |
NZ245772A (en) | 1995-05-26 |
NO930411D0 (no) | 1993-02-05 |
PL297666A1 (en) | 1993-10-18 |
IL104624A0 (en) | 1993-06-10 |
DE69302109D1 (de) | 1996-05-15 |
JPH05286957A (ja) | 1993-11-02 |
HUT63840A (en) | 1993-10-28 |
CZ13393A3 (en) | 1993-10-13 |
TW224094B (zh) | 1994-05-21 |
ATE136546T1 (de) | 1996-04-15 |
NO930411L (no) | 1993-08-09 |
US5332757A (en) | 1994-07-26 |
ES2086878T3 (es) | 1996-07-01 |
GB9300894D0 (en) | 1993-03-10 |
EP0555068B1 (en) | 1996-04-10 |
GR3019634T3 (en) | 1996-07-31 |
ZW1293A1 (en) | 1993-09-29 |
FI930475A0 (fi) | 1993-02-03 |
CA2088864A1 (en) | 1993-08-08 |
DE69302109T2 (de) | 1996-10-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SK6993A3 (en) | Oxime derivatives, process for their manufacture, pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors | |
US5276037A (en) | Heterocyclic 5-lipoxygenase inhibitors | |
CA2377803C (en) | Phenyl sulfamate derivatives | |
SK5542001A3 (en) | Prostaglandin endoperoxide h synthase biosynthesis inhibitors | |
JP2005533858A (ja) | 化合物 | |
HUT77517A (hu) | Biciklusos tetrahidro-pirazolo-piridin-származékok, alkalmazásuk és ilyen vegyületeket tartalmazó gyógyászati készítmények | |
JPH03135936A (ja) | アルコールおよびエーテル誘導体、その製法並びに該誘導体含有する5‐リポキシゲナーゼ阻害製薬学的組成物 | |
EP0532239B1 (en) | Benzenesulphonamide derivatives as 5-lipoxygenase inhibitors | |
US5236948A (en) | Sulphonamide derivatives | |
EP0623614A1 (en) | 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | |
US5334614A (en) | Hydroxylamine derivatives | |
US5457125A (en) | Oxime derivatives | |
EP0570197B1 (en) | Hydroxylamine derivatives | |
US5258399A (en) | Sulphonamide derivatives | |
EP0681576A1 (en) | Oxime derivatives | |
EP0570196B1 (en) | Oxime derivatives | |
US5453439A (en) | Hydroxylamine derivatives | |
JPS5988458A (ja) | アミン誘導体およびその塩 | |
US5478843A (en) | Thiazole derivatives | |
EP0610032A1 (en) | Acetanilide derivatives | |
EP0636624A1 (en) | Thiazole derivatives as lipoxygenase inhibitors | |
WO1995004055A1 (en) | Thiazole derivatives as lipoxygenase inhibitors | |
CA2113913A1 (en) | Acetanilide derivatives |