TW223017B - - Google Patents
Info
- Publication number
- TW223017B TW223017B TW082106192A TW82106192A TW223017B TW 223017 B TW223017 B TW 223017B TW 082106192 A TW082106192 A TW 082106192A TW 82106192 A TW82106192 A TW 82106192A TW 223017 B TW223017 B TW 223017B
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl
- hydrogen
- formula
- compounds
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92979592A | 1992-08-13 | 1992-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW223017B true TW223017B (zh) | 1994-05-01 |
Family
ID=25458467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082106192A TW223017B (zh) | 1992-08-13 | 1993-08-03 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5567722A (zh) |
| EP (1) | EP0655057B1 (zh) |
| JP (1) | JPH08500111A (zh) |
| CN (1) | CN1039997C (zh) |
| AT (1) | ATE158279T1 (zh) |
| AU (2) | AU4530693A (zh) |
| DE (1) | DE69314041T2 (zh) |
| DK (1) | DK0655057T3 (zh) |
| ES (1) | ES2107049T3 (zh) |
| GR (1) | GR3025640T3 (zh) |
| IL (1) | IL106641A (zh) |
| MX (1) | MX9304882A (zh) |
| MY (1) | MY110826A (zh) |
| TW (1) | TW223017B (zh) |
| WO (2) | WO1994004499A1 (zh) |
| ZA (1) | ZA935619B (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09508382A (ja) * | 1994-01-28 | 1997-08-26 | ジ・アップジョン・カンパニー | Ｋ−チャネル遮断薬用シアノグアニジン類 |
| AUPN193095A0 (en) * | 1995-03-24 | 1995-04-27 | Polychip Pharmaceuticals Pty Ltd | Potassium ion channel blockers |
| AR008290A1 (es) * | 1996-08-15 | 1999-12-29 | Smithkline Beecham Corp | Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios. |
| WO1998006398A1 (en) * | 1996-08-15 | 1998-02-19 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| EP1917244A2 (de) | 2005-08-24 | 2008-05-07 | Abbott GmbH & Co. KG | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| CN113683535B (zh) * | 2020-05-18 | 2022-08-30 | 中国药科大学 | 含氰胍结构的化合物及其制备方法与用途 |
| CN112042664B (zh) * | 2020-09-18 | 2022-06-10 | 广州古神生物科技有限公司 | 防霉抗菌剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1489879A (en) * | 1974-12-20 | 1977-10-26 | Leo Pharm Prod Ltd | N'-cyano-n'-3-pyridylguanidines |
| NL8000869A (nl) * | 1979-02-16 | 1980-08-19 | Eisai Co Ltd | Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. |
| JPH01166119A (ja) * | 1987-12-23 | 1989-06-30 | Hitachi Ltd | データ入力装置の制御方式 |
| NZ229828A (en) * | 1988-08-09 | 1992-03-26 | Squibb & Sons Inc | Aryl cyanoguanidine derivatives and pharmaceutical compositions |
| CA2009074C (en) * | 1989-02-03 | 1999-07-27 | David Wayne Robertson | Improvements in and relating to guanidine derivatives |
| US5006523A (en) * | 1989-10-26 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers |
-
1993
- 1993-06-11 WO PCT/US1993/005458 patent/WO1994004499A1/en active Application Filing
- 1993-06-11 AU AU45306/93A patent/AU4530693A/en not_active Abandoned
- 1993-07-21 AT AT93917262T patent/ATE158279T1/de not_active IP Right Cessation
- 1993-07-21 AU AU46831/93A patent/AU4683193A/en not_active Abandoned
- 1993-07-21 DK DK93917262.3T patent/DK0655057T3/da active
- 1993-07-21 WO PCT/US1993/006752 patent/WO1994004500A1/en active IP Right Grant
- 1993-07-21 ES ES93917262T patent/ES2107049T3/es not_active Expired - Lifetime
- 1993-07-21 EP EP93917262A patent/EP0655057B1/en not_active Expired - Lifetime
- 1993-07-21 JP JP6506258A patent/JPH08500111A/ja active Pending
- 1993-07-21 DE DE69314041T patent/DE69314041T2/de not_active Expired - Fee Related
- 1993-08-03 ZA ZA935619A patent/ZA935619B/xx unknown
- 1993-08-03 TW TW082106192A patent/TW223017B/zh active
- 1993-08-07 MY MYPI93001565A patent/MY110826A/en unknown
- 1993-08-10 IL IL10664193A patent/IL106641A/en not_active IP Right Cessation
- 1993-08-12 MX MX9304882A patent/MX9304882A/es not_active IP Right Cessation
- 1993-08-13 CN CN93117781A patent/CN1039997C/zh not_active Expired - Fee Related
-
1995
- 1995-02-06 US US08/384,562 patent/US5567722A/en not_active Expired - Fee Related
-
1997
- 1997-12-10 GR GR970403292T patent/GR3025640T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0655057A1 (en) | 1995-05-31 |
| ES2107049T3 (es) | 1997-11-16 |
| JPH08500111A (ja) | 1996-01-09 |
| ZA935619B (en) | 1995-02-03 |
| WO1994004500A1 (en) | 1994-03-03 |
| DE69314041T2 (de) | 1998-02-05 |
| CN1090575A (zh) | 1994-08-10 |
| GR3025640T3 (en) | 1998-03-31 |
| AU4530693A (en) | 1994-03-15 |
| IL106641A0 (en) | 1993-12-08 |
| WO1994004499A1 (en) | 1994-03-03 |
| US5567722A (en) | 1996-10-22 |
| MX9304882A (es) | 1994-07-29 |
| CN1039997C (zh) | 1998-09-30 |
| DE69314041D1 (de) | 1997-10-23 |
| DK0655057T3 (da) | 1998-04-14 |
| AU4683193A (en) | 1994-03-15 |
| MY110826A (en) | 1999-05-31 |
| IL106641A (en) | 2001-01-11 |
| EP0655057B1 (en) | 1997-09-17 |
| ATE158279T1 (de) | 1997-10-15 |
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