TW202345788A - 配體-藥物偶聯物及其用途 - Google Patents

配體-藥物偶聯物及其用途 Download PDF

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Publication number
TW202345788A
TW202345788A TW112112673A TW112112673A TW202345788A TW 202345788 A TW202345788 A TW 202345788A TW 112112673 A TW112112673 A TW 112112673A TW 112112673 A TW112112673 A TW 112112673A TW 202345788 A TW202345788 A TW 202345788A
Authority
TW
Taiwan
Prior art keywords
seq
alkyl
ligand
antibody
pharmaceutically acceptable
Prior art date
Application number
TW112112673A
Other languages
English (en)
Chinese (zh)
Inventor
付雅媛
柴曉鵑
劉力鋒
陳常艷
嚴玉璽
唐鋒
曹卓曉
唐任宏
Original Assignee
大陸商江蘇先聲藥業有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 大陸商江蘇先聲藥業有限公司 filed Critical 大陸商江蘇先聲藥業有限公司
Publication of TW202345788A publication Critical patent/TW202345788A/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW112112673A 2022-04-01 2023-03-31 配體-藥物偶聯物及其用途 TW202345788A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CN2022103394974 2022-04-01
CN202210339497 2022-04-01
CN2022103954815 2022-04-15
CN202210395481 2022-04-15
CN202211392212 2022-11-08
CN202211392212X 2022-11-08

Publications (1)

Publication Number Publication Date
TW202345788A true TW202345788A (zh) 2023-12-01

Family

ID=88199431

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112112673A TW202345788A (zh) 2022-04-01 2023-03-31 配體-藥物偶聯物及其用途

Country Status (2)

Country Link
TW (1) TW202345788A (fr)
WO (1) WO2023186072A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7125843B2 (en) * 2001-10-19 2006-10-24 Neose Technologies, Inc. Glycoconjugates including more than one peptide
WO2010126953A1 (fr) * 2009-04-29 2010-11-04 Gilead Sciences, Inc. Composés bêta-agonistes liés à des corticostéroïdes pour une utilisation en thérapie
KR20220119529A (ko) * 2016-06-02 2022-08-29 애브비 인코포레이티드 글루코코르티코이드 수용체 작용제 및 이의 면역접합체

Also Published As

Publication number Publication date
WO2023186072A1 (fr) 2023-10-05

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