TW202342496A - 介白素-23受體之肽抑制劑及其醫藥組成物 - Google Patents

介白素-23受體之肽抑制劑及其醫藥組成物 Download PDF

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Publication number
TW202342496A
TW202342496A TW112103335A TW112103335A TW202342496A TW 202342496 A TW202342496 A TW 202342496A TW 112103335 A TW112103335 A TW 112103335A TW 112103335 A TW112103335 A TW 112103335A TW 202342496 A TW202342496 A TW 202342496A
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Taiwan
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composition
amount
formula
compound
solvate
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TW112103335A
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English (en)
Chinese (zh)
Inventor
杰拉爾丁 布洛克斯
大衛 貝斯林
克萊拉 安杜克斯坎圖
克里斯托弗 戴多布拉勒
吉爾達斯 丹尼奧
朱斯蒂諾 迪普雷托羅
盧茲卡 克拉克歐維克
娜塔莉 梅藤斯
賽哈爾 帕塔爾
貝蒂 派德森
戈帕爾 拉詹
大軍 孫
菲利浦 費南德斯
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比利時商健生藥品公司
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Application filed by 比利時商健生藥品公司 filed Critical 比利時商健生藥品公司
Publication of TW202342496A publication Critical patent/TW202342496A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TW112103335A 2022-02-01 2023-01-31 介白素-23受體之肽抑制劑及其醫藥組成物 TW202342496A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263305631P 2022-02-01 2022-02-01
US63/305,631 2022-02-01

Publications (1)

Publication Number Publication Date
TW202342496A true TW202342496A (zh) 2023-11-01

Family

ID=85556753

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112103335A TW202342496A (zh) 2022-02-01 2023-01-31 介白素-23受體之肽抑制劑及其醫藥組成物

Country Status (13)

Country Link
EP (1) EP4472999A1 (https=)
JP (1) JP2025506374A (https=)
KR (1) KR20240137102A (https=)
CN (1) CN118829647A (https=)
AU (1) AU2023215245A1 (https=)
CA (1) CA3250172A1 (https=)
CL (1) CL2024002263A1 (https=)
IL (1) IL314629A (https=)
MX (1) MX2024009477A (https=)
PE (1) PE20241895A1 (https=)
TW (1) TW202342496A (https=)
UY (1) UY40135A (https=)
WO (1) WO2023150500A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL322423A (en) 2023-01-31 2025-09-01 Janssen Pharmaceutica Nv Methods for preparing crystalline peptide inhibitors of the interleukin-23 receptor
WO2025062347A1 (en) * 2023-09-21 2025-03-27 Janssen Pharmaceutica Nv Interleukin-23 receptor antagonist for use in the treatment of ulcerative colitis
WO2025151385A1 (en) * 2024-01-08 2025-07-17 Janssen Pharmaceutica Nv Peptide inhibitors of interleukin-23 receptor and uses thereof
WO2025163534A1 (en) * 2024-01-31 2025-08-07 Janssen Pharmaceutica Nv Crystal form of a peptide inhibitor of interleukin-23 receptor
WO2025243217A1 (en) * 2024-05-22 2025-11-27 Janssen Pharmaceutica Nv Crystal forms of peptide molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946150B2 (en) 2011-06-14 2015-02-03 Medical Diagnostic Laboratories, LLC. Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
CA3167751A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

Also Published As

Publication number Publication date
UY40135A (es) 2023-08-31
IL314629A (en) 2024-09-01
CA3250172A1 (en) 2023-08-10
CN118829647A (zh) 2024-10-22
EP4472999A1 (en) 2024-12-11
KR20240137102A (ko) 2024-09-19
CL2024002263A1 (es) 2025-02-07
MX2024009477A (es) 2024-11-08
PE20241895A1 (es) 2024-09-19
WO2023150500A1 (en) 2023-08-10
JP2025506374A (ja) 2025-03-11
AU2023215245A1 (en) 2024-09-19

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