IL314629A - Peptide inhibitors of the interleukin-23 receptor and pharmaceutical preparations thereof - Google Patents

Peptide inhibitors of the interleukin-23 receptor and pharmaceutical preparations thereof

Info

Publication number
IL314629A
IL314629A IL314629A IL31462924A IL314629A IL 314629 A IL314629 A IL 314629A IL 314629 A IL314629 A IL 314629A IL 31462924 A IL31462924 A IL 31462924A IL 314629 A IL314629 A IL 314629A
Authority
IL
Israel
Prior art keywords
interleukin
receptor
pharmaceutical compositions
peptide inhibitors
peptide
Prior art date
Application number
IL314629A
Other languages
English (en)
Hebrew (he)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL314629A publication Critical patent/IL314629A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL314629A 2022-02-01 2023-01-31 Peptide inhibitors of the interleukin-23 receptor and pharmaceutical preparations thereof IL314629A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263305631P 2022-02-01 2022-02-01
PCT/US2023/061651 WO2023150500A1 (en) 2022-02-01 2023-01-31 Peptide inhibitors of interleukin-23 receptor and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
IL314629A true IL314629A (en) 2024-09-01

Family

ID=85556753

Family Applications (1)

Application Number Title Priority Date Filing Date
IL314629A IL314629A (en) 2022-02-01 2023-01-31 Peptide inhibitors of the interleukin-23 receptor and pharmaceutical preparations thereof

Country Status (13)

Country Link
EP (1) EP4472999A1 (https=)
JP (1) JP2025506374A (https=)
KR (1) KR20240137102A (https=)
CN (1) CN118829647A (https=)
AU (1) AU2023215245A1 (https=)
CA (1) CA3250172A1 (https=)
CL (1) CL2024002263A1 (https=)
IL (1) IL314629A (https=)
MX (1) MX2024009477A (https=)
PE (1) PE20241895A1 (https=)
TW (1) TW202342496A (https=)
UY (1) UY40135A (https=)
WO (1) WO2023150500A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL322423A (en) 2023-01-31 2025-09-01 Janssen Pharmaceutica Nv Methods for preparing crystalline peptide inhibitors of the interleukin-23 receptor
WO2025062347A1 (en) * 2023-09-21 2025-03-27 Janssen Pharmaceutica Nv Interleukin-23 receptor antagonist for use in the treatment of ulcerative colitis
WO2025151385A1 (en) * 2024-01-08 2025-07-17 Janssen Pharmaceutica Nv Peptide inhibitors of interleukin-23 receptor and uses thereof
WO2025163534A1 (en) * 2024-01-31 2025-08-07 Janssen Pharmaceutica Nv Crystal form of a peptide inhibitor of interleukin-23 receptor
WO2025243217A1 (en) * 2024-05-22 2025-11-27 Janssen Pharmaceutica Nv Crystal forms of peptide molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946150B2 (en) 2011-06-14 2015-02-03 Medical Diagnostic Laboratories, LLC. Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
CA3167751A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

Also Published As

Publication number Publication date
TW202342496A (zh) 2023-11-01
UY40135A (es) 2023-08-31
CA3250172A1 (en) 2023-08-10
CN118829647A (zh) 2024-10-22
EP4472999A1 (en) 2024-12-11
KR20240137102A (ko) 2024-09-19
CL2024002263A1 (es) 2025-02-07
MX2024009477A (es) 2024-11-08
PE20241895A1 (es) 2024-09-19
WO2023150500A1 (en) 2023-08-10
JP2025506374A (ja) 2025-03-11
AU2023215245A1 (en) 2024-09-19

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