TW202330014A - 含有胜肽化合物及界面活性劑之組成物 - Google Patents

含有胜肽化合物及界面活性劑之組成物 Download PDF

Info

Publication number
TW202330014A
TW202330014A TW111138589A TW111138589A TW202330014A TW 202330014 A TW202330014 A TW 202330014A TW 111138589 A TW111138589 A TW 111138589A TW 111138589 A TW111138589 A TW 111138589A TW 202330014 A TW202330014 A TW 202330014A
Authority
TW
Taiwan
Prior art keywords
compound
group
surfactant
less
carnitine
Prior art date
Application number
TW111138589A
Other languages
English (en)
Chinese (zh)
Inventor
中江慎一
髙野隆介
唐蘅敏
櫻井裕治
Original Assignee
日商中外製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商中外製藥股份有限公司 filed Critical 日商中外製藥股份有限公司
Priority to KR1020247018318A priority Critical patent/KR20250002095A/ko
Priority to EP23799441.3A priority patent/EP4406546A4/en
Priority to JP2024519189A priority patent/JPWO2023214509A1/ja
Priority to PCT/JP2023/015658 priority patent/WO2023214509A1/ja
Priority to US18/851,191 priority patent/US20250186542A1/en
Publication of TW202330014A publication Critical patent/TW202330014A/zh
Priority to EP23877311.3A priority patent/EP4582092A1/en
Priority to PCT/JP2023/036892 priority patent/WO2024080308A1/ja
Priority to JP2024551721A priority patent/JPWO2024080308A1/ja

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
TW111138589A 2021-10-13 2022-10-12 含有胜肽化合物及界面活性劑之組成物 TW202330014A (zh)

Priority Applications (8)

Application Number Priority Date Filing Date Title
KR1020247018318A KR20250002095A (ko) 2022-05-02 2023-04-19 계면활성제와 병용하기 위한 펩타이드 화합물을 포함하는 조성물
EP23799441.3A EP4406546A4 (en) 2022-05-02 2023-04-19 COMPOSITION CONTAINING A PEPTIDE COMPOUND FOR USE WITH A SURFACTANT
JP2024519189A JPWO2023214509A1 (https=) 2022-05-02 2023-04-19
PCT/JP2023/015658 WO2023214509A1 (ja) 2022-05-02 2023-04-19 界面活性剤と併用するためのペプチド化合物を含む組成物
US18/851,191 US20250186542A1 (en) 2022-05-02 2023-04-19 Composition containing peptide compound for use with surfactant
EP23877311.3A EP4582092A1 (en) 2022-10-12 2023-10-11 Composition containing peptide, surfactant, and polymer
PCT/JP2023/036892 WO2024080308A1 (ja) 2022-10-12 2023-10-11 ペプチド、界面活性剤及びポリマーを含む組成物
JP2024551721A JPWO2024080308A1 (https=) 2022-10-12 2023-10-11

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2021167912 2021-10-13
JP2021-167912 2021-10-13
JP2022075833 2022-05-02
JP2022-075833 2022-05-02
EP22192611 2022-08-29
EP22192611.6 2022-08-29

Publications (1)

Publication Number Publication Date
TW202330014A true TW202330014A (zh) 2023-08-01

Family

ID=83546822

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111138589A TW202330014A (zh) 2021-10-13 2022-10-12 含有胜肽化合物及界面活性劑之組成物

Country Status (7)

Country Link
US (1) US20250302912A1 (https=)
EP (2) EP4609875A3 (https=)
JP (1) JPWO2023063376A1 (https=)
KR (1) KR20240070705A (https=)
DK (1) DK4166133T3 (https=)
TW (1) TW202330014A (https=)
WO (1) WO2023063376A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI787670B (zh) 2011-12-28 2022-12-21 日商中外製藥股份有限公司 具有環狀部之胜肽化合物及其醫藥組成物
WO2024219446A1 (ja) * 2023-04-19 2024-10-24 中外製薬株式会社 環状ペプチド化合物及び界面活性剤を含む組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH679277A5 (https=) * 1989-02-09 1992-01-31 Sandoz Ag
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
TW200409644A (en) * 2002-12-04 2004-06-16 Bio Max Inc Improved carrier system for cyclosporin pharmaceutical compositions
US8093207B2 (en) 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
AU2012271691A1 (en) * 2011-06-14 2014-01-16 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
TWI787670B (zh) * 2011-12-28 2022-12-21 日商中外製藥股份有限公司 具有環狀部之胜肽化合物及其醫藥組成物
CN104853749A (zh) * 2012-09-17 2015-08-19 塔瑞克斯制药有限公司 血管紧张素的口服制剂
DE102013219920A1 (de) * 2013-10-01 2015-04-02 Henkel Ag & Co. Kgaa leistungsgesteigerte Haarbehandlungsmittel
WO2016004067A1 (en) * 2014-06-30 2016-01-07 Stealth Biotherapeutics Corp Aromatic-cationic peptide formulations, compositions and methods of use
JP7232758B2 (ja) * 2017-06-09 2023-03-06 中外製薬株式会社 膜透過性の高い環状ペプチド化合物、及びこれを含むライブラリ
WO2018225851A1 (ja) * 2017-06-09 2018-12-13 中外製薬株式会社 Ｎ－置換アミノ酸を含むペプチドの合成方法
PE20221323A1 (es) * 2019-11-07 2022-09-09 Chugai Pharmaceutical Co Ltd Compuesto de peptidos ciclicos que tiene accion inhibidora de kras

Also Published As

Publication number Publication date
WO2023063376A1 (ja) 2023-04-20
EP4609875A3 (en) 2025-12-03
DK4166133T3 (da) 2025-09-01
JPWO2023063376A1 (https=) 2023-04-20
US20250302912A1 (en) 2025-10-02
EP4166133B1 (en) 2025-07-23
KR20240070705A (ko) 2024-05-21
EP4166133A1 (en) 2023-04-19
EP4609875A2 (en) 2025-09-03

Similar Documents

Publication Publication Date Title
CN120897751A (zh) 含有环肽化合物和表面活性剂的组合物
EP0498069B1 (en) New use of peptide derivative
FI97524C (fi) Menetelmä syklosporiinia sisältävän farmaseuttisen koostumuksen valmistamiseksi
TW202330014A (zh) 含有胜肽化合物及界面活性劑之組成物
BRPI0813733A2 (pt) composto com atividade inibidora de hcv, sua composição farmacêutica e seu uso.
CN102464701B (zh) 一类新型化合物、其制备方法及用途
TW202406566A (zh) 包含用於與界面活性劑結合使用之胜肽化合物的組合物
JPH0419208B2 (https=)
PT1476196E (pt) Formulação de solução solida oral de uma substância activa fracamente solúvel em água
KR20220002901A (ko) 멜플루펜을 포함하는 신규한 제형
TW202402319A (zh) 含有包含聚氧乙烯構造的油性成分之化合物製劑
JPS59112925A (ja) 鼻腔内投与用組成物及びその製造方法
KR940006770B1 (ko) 머캅토-아실아미노산 고혈압 치료제
HK40111890A (zh) 包含肽化合物和表面活性剂的组合物
HK40111891A (zh) 用於与表面活性剂联用的包含肽化合物的组合物
EP4582092A1 (en) Composition containing peptide, surfactant, and polymer
CN118176012A (zh) 包含肽化合物和表面活性剂的组合物
KR20240039185A (ko) 브래디키닌 b2-수용체 길항제의 경구 투여용 지질 기반 조성물
WO1994020143A1 (fr) Inhibiteur d'isomerisation optique
HK40126562A (zh) 含有环肽化合物和表面活性剂的组合物
EP4596570A1 (en) Src inhibitors and uses thereof
HK40111865A (zh) 含有包含聚氧乙烯结构的油性成分的化合物制剂
KR20240036250A (ko) 일산화질소 소거능이 향상된 페닐렌디아민계 화합물, 및 이를 함유하는 염증성 질환의 예방 또는 치료용 약학적 조성물
EA012982B1 (ru) Стабилизированная фармацевтическая композиция лейкотриен в(ltb) агента
CN101400352A (zh) 用于治疗和预防疾病的组合物和方法