TW202313979A - 特異性靶向間皮素的ｃａｒ表現免疫細胞及其用途 - Google Patents

特異性靶向間皮素的ｃａｒ表現免疫細胞及其用途 Download PDF

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TW202313979A
TW202313979A TW111128457A TW111128457A TW202313979A TW 202313979 A TW202313979 A TW 202313979A TW 111128457 A TW111128457 A TW 111128457A TW 111128457 A TW111128457 A TW 111128457A TW 202313979 A TW202313979 A TW 202313979A
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seq
nucleic acid
sequence
acid molecule
sequence identity
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TW111128457A
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武千央
蓋瑞 沙畢羅
葛西義明
星玥 何
湘塔爾 庫函
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日商武田藥品工業股份有限公司
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/35—Cytokines
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4254—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • A61K40/4255—Mesothelin [MSLN]
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TW111128457A 2021-07-29 2022-07-28 特異性靶向間皮素的ｃａｒ表現免疫細胞及其用途 TW202313979A (zh)

Applications Claiming Priority (4)

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US202163227115P 2021-07-29 2021-07-29
US63/227,115 2021-07-29
US202263306862P 2022-02-04 2022-02-04
US63/306,862 2022-02-04

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TW202313979A true TW202313979A (zh) 2023-04-01

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US (1) US20240374721A1 (cg-RX-API-DMAC10.html)
EP (1) EP4377355A4 (cg-RX-API-DMAC10.html)
JP (1) JP2024528052A (cg-RX-API-DMAC10.html)
KR (1) KR20240038723A (cg-RX-API-DMAC10.html)
AU (1) AU2022316980A1 (cg-RX-API-DMAC10.html)
CA (1) CA3227745A1 (cg-RX-API-DMAC10.html)
CO (1) CO2024001484A2 (cg-RX-API-DMAC10.html)
IL (1) IL309914A (cg-RX-API-DMAC10.html)
MX (1) MX2024001364A (cg-RX-API-DMAC10.html)
TW (1) TW202313979A (cg-RX-API-DMAC10.html)
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EA202190624A1 (ru) * 2018-08-31 2021-06-09 Нойл-Иммьюн Байотек, Инк. Car-экспрессирующие т-клетки и car-экспрессирующий вектор
JP2026518850A (ja) 2023-04-27 2026-06-10 武田薬品工業株式会社 Ｃｄ５６＋／ｃｄ３－細胞の増殖方法
CN119101166A (zh) * 2023-06-08 2024-12-10 博生吉医药科技(苏州)有限公司 B7-H3嵌合抗原受体修饰的Vδ1 T细胞及其应用
JPWO2025094915A1 (cg-RX-API-DMAC10.html) 2023-10-30 2025-05-08
WO2025140683A1 (zh) * 2023-12-29 2025-07-03 北京鼎成肽源生物技术有限公司 表达趋化因子10和白介素15的工程化免疫细胞

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US9272002B2 (en) 2011-10-28 2016-03-01 The Trustees Of The University Of Pennsylvania Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
CN108728458B (zh) * 2017-04-21 2021-11-16 上海恒润达生生物科技股份有限公司 靶向mesothelin的嵌合抗原受体并联合表达IL-15的方法和用途
PL3618842T3 (pl) * 2017-05-01 2024-02-19 Juno Therapeutics, Inc. Kombinacja terapii komórkowej i związku immunomodulującego
US11241485B2 (en) 2017-06-12 2022-02-08 Obsidian Therapeutics, Inc. PDE5 compositions and methods for immunotherapy
MX428412B (es) * 2017-12-24 2025-11-13 Noile Immune Biotech Inc Celula inmunocompetente que expresa una molecula de superficie celular que reconoce especificamente la mesotelina humana, il-7 y ccl19
WO2019160956A1 (en) * 2018-02-13 2019-08-22 Novartis Ag Chimeric antigen receptor therapy in combination with il-15r and il15
EA202190624A1 (ru) 2018-08-31 2021-06-09 Нойл-Иммьюн Байотек, Инк. Car-экспрессирующие т-клетки и car-экспрессирующий вектор

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IL309914A (en) 2024-03-01
EP4377355A4 (en) 2025-06-18
WO2023009700A3 (en) 2023-04-13
US20240374721A1 (en) 2024-11-14
KR20240038723A (ko) 2024-03-25
AU2022316980A1 (en) 2024-01-25
CO2024001484A2 (es) 2024-02-26
JP2024528052A (ja) 2024-07-26
EP4377355A2 (en) 2024-06-05
WO2023009700A2 (en) 2023-02-02
CA3227745A1 (en) 2023-02-02
MX2024001364A (es) 2024-02-27

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