TW202305004A - 靶向ａｄｇｒｅ２及／或ｃｌｅｃ１２ａ之嵌合受體及其用途 - Google Patents

靶向ａｄｇｒｅ２及／或ｃｌｅｃ１２ａ之嵌合受體及其用途 Download PDF

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TW202305004A
TW202305004A TW111115910A TW111115910A TW202305004A TW 202305004 A TW202305004 A TW 202305004A TW 111115910 A TW111115910 A TW 111115910A TW 111115910 A TW111115910 A TW 111115910A TW 202305004 A TW202305004 A TW 202305004A
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amino acid
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TW111115910A
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米歇爾 薩德連
莎夏 Ｐ 豪布纳
索托 約根 曼西拉
蓋瑞 夏皮羅
星月 何
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美國紀念斯隆凱特林癌症中心
美商索隆 基特林癌症研究協會
美國癌症及相關疾病紀念醫院
美商千禧製藥公司
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Publication of TW202305004A publication Critical patent/TW202305004A/zh

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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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TW111115910A 2021-04-26 2022-04-26 靶向ａｄｇｒｅ２及／或ｃｌｅｃ１２ａ之嵌合受體及其用途 TW202305004A (zh)

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US202163179799P 2021-04-26 2021-04-26
US63/179,799 2021-04-26
US202163287655P 2021-12-09 2021-12-09
US63/287,655 2021-12-09

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US (2) US12331129B2 (https=)
EP (1) EP4330275A4 (https=)
JP (1) JP2024514974A (https=)
KR (1) KR20240005720A (https=)
AU (1) AU2022267219A1 (https=)
BR (1) BR112023022297A2 (https=)
CA (1) CA3212596A1 (https=)
CL (1) CL2023003185A1 (https=)
CO (1) CO2023015212A2 (https=)
EC (1) ECSP23081501A (https=)
IL (1) IL306141A (https=)
MX (1) MX2023012681A (https=)
PE (1) PE20250158A1 (https=)
TW (1) TW202305004A (https=)
WO (1) WO2022232016A2 (https=)

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MX2023011712A (es) 2021-04-26 2023-10-12 Millennium Pharm Inc Anticuerpos anti receptor de adhesion acoplado a proteinas g e2 (adgre2) y usos de los mismos.
CA3216770A1 (en) * 2021-04-26 2022-11-03 Tomoki Yoshihara Anti-clec12a antibodies and uses thereof
CN120152735A (zh) * 2022-10-25 2025-06-13 武田药品工业株式会社 Adgre2嵌合受体nk细胞组合物和使用方法
WO2024238565A1 (en) * 2023-05-15 2024-11-21 Vor Biopharma Inc. Egf-like module containing mucin-like hormone-like 2 (erm2) binding agents and methods of use thereof
WO2025243243A1 (en) * 2024-05-24 2025-11-27 Janssen Biotech, Inc. Bispecific antibody targeting emr2 (cd312) and the t-cell receptor trbv19

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MX2023011712A (es) 2021-04-26 2023-10-12 Millennium Pharm Inc Anticuerpos anti receptor de adhesion acoplado a proteinas g e2 (adgre2) y usos de los mismos.
CA3216770A1 (en) 2021-04-26 2022-11-03 Tomoki Yoshihara Anti-clec12a antibodies and uses thereof

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CL2023003185A1 (es) 2024-04-26
CA3212596A1 (en) 2022-11-03
EP4330275A2 (en) 2024-03-06
AU2022267219A1 (en) 2023-10-05
US20220363775A1 (en) 2022-11-17
PE20250158A1 (es) 2025-01-22
CO2023015212A2 (es) 2023-11-20
EP4330275A4 (en) 2026-04-08
JP2024514974A (ja) 2024-04-03
US12331129B2 (en) 2025-06-17
US20250250356A1 (en) 2025-08-07
WO2022232016A3 (en) 2023-01-05
ECSP23081501A (es) 2023-11-30
WO2022232016A2 (en) 2022-11-03
KR20240005720A (ko) 2024-01-12
BR112023022297A2 (pt) 2023-12-26
MX2023012681A (es) 2023-11-07

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