TW202300180A - 右心室心律失常性心肌病之基因療法組合物及治療 - Google Patents

右心室心律失常性心肌病之基因療法組合物及治療 Download PDF

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TW202300180A
TW202300180A TW111110077A TW111110077A TW202300180A TW 202300180 A TW202300180 A TW 202300180A TW 111110077 A TW111110077 A TW 111110077A TW 111110077 A TW111110077 A TW 111110077A TW 202300180 A TW202300180 A TW 202300180A
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pkp2
cardiomyocytes
fold
gene therapy
isoform
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TW111110077A
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湯瑪士 維伊特
裘莉 迪蒙索
派利 艾略特
維吉尼 馬里奧特
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英商Ｕｃｌ商業有限責任公司
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14145—Special targeting system for viral vectors

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TW111110077A 2021-03-19 2022-03-18 右心室心律失常性心肌病之基因療法組合物及治療 TW202300180A (zh)

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US202163163393P 2021-03-19 2021-03-19
US63/163,393 2021-03-19

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US (1) US20240042059A1 (https=)
EP (1) EP4308172A2 (https=)
JP (1) JP2024512483A (https=)
KR (1) KR20230159471A (https=)
CN (1) CN117715660A (https=)
AU (1) AU2022239846A1 (https=)
BR (1) BR112023018944A2 (https=)
CA (1) CA3212043A1 (https=)
IL (1) IL305959A (https=)
MX (1) MX2023011035A (https=)
TW (1) TW202300180A (https=)
WO (1) WO2022195074A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3947700A4 (en) 2019-04-01 2023-01-04 Tenaya Therapeutics, Inc. Adeno-associated virus with engineered capsid
KR20230043869A (ko) 2020-08-07 2023-03-31 스페이스크래프트 세븐, 엘엘씨 Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법
BR112023006305A2 (pt) * 2020-10-09 2023-05-09 Tenaya Therapeutics Inc Métodos e composições de terapia gênica com placofilina-2
US11781156B2 (en) 2020-10-09 2023-10-10 Tenaya Therapeutics, Inc. Plakophillin-2 gene therapy methods and compositions
CN115851751A (zh) * 2022-12-21 2023-03-28 百世诺（北京）医疗科技有限公司 肥厚型心肌病变异基因tnnt2及其应用
WO2025189238A1 (en) * 2024-03-12 2025-09-18 Murdoch Children's Research Institute Treatment methods for muscle-associated diseases
WO2025238184A1 (en) * 2024-05-15 2025-11-20 Stichting Amsterdam UMC Scn10a-short gene therapy to restore cardiac impulse conduction and to protect against cardiac arrhythmia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12098385B2 (en) * 2017-09-20 2024-09-24 The Regents Of The University Of California Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy
ES2976559T3 (es) * 2017-09-20 2024-08-05 Univ California Terapia génica con conexina 43 para restaurar la función eléctrica y cardíaca y la estructura cardíaca, en la miocardiopatía arritmogénica del ventrículo derecho
CN109004092A (zh) 2018-06-29 2018-12-14 云谷（固安）科技有限公司 有机电致发光器件和有机电致发光装置
TWI897882B (zh) * 2019-09-20 2025-09-21 英商Ｕｃｌ商業有限責任公司 右心室心律失常性心肌病之基因療法組合物及治療
KR20230043869A (ko) * 2020-08-07 2023-03-31 스페이스크래프트 세븐, 엘엘씨 Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법
BR112023006305A2 (pt) 2020-10-09 2023-05-09 Tenaya Therapeutics Inc Métodos e composições de terapia gênica com placofilina-2
US11781156B2 (en) * 2020-10-09 2023-10-10 Tenaya Therapeutics, Inc. Plakophillin-2 gene therapy methods and compositions

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WO2022195074A3 (en) 2022-11-10
AU2022239846A1 (en) 2023-10-26
IL305959A (en) 2023-11-01
CN117715660A (zh) 2024-03-15
US20240042059A1 (en) 2024-02-08
BR112023018944A2 (pt) 2023-12-26
CA3212043A1 (en) 2022-09-22
EP4308172A2 (en) 2024-01-24
WO2022195074A2 (en) 2022-09-22
JP2024512483A (ja) 2024-03-19
MX2023011035A (es) 2024-02-09
AU2022239846A9 (en) 2023-11-09
KR20230159471A (ko) 2023-11-21

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