TW202241887A - 4-胺基-3-(4-苯氧基苯基)-1,3-二氫-2h-咪唑並[4,5-c]吡啶-2-酮之衍生物及其鹽類 - Google Patents

4-胺基-3-(4-苯氧基苯基)-1,3-二氫-2h-咪唑並[4,5-c]吡啶-2-酮之衍生物及其鹽類 Download PDF

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Publication number
TW202241887A
TW202241887A TW110148094A TW110148094A TW202241887A TW 202241887 A TW202241887 A TW 202241887A TW 110148094 A TW110148094 A TW 110148094A TW 110148094 A TW110148094 A TW 110148094A TW 202241887 A TW202241887 A TW 202241887A
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Taiwan
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compound
salt
formula
pure
purity
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TW110148094A
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Chinese (zh)
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凱瑟琳 阿拉貝爾
派翠西亞 莫里納
塞賓 柏伊納德
達明 莎拉貝瑞
塞爾吉 帕拉德
塞巴斯汀 羅伊
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美商健臻公司
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Publication of TW202241887A publication Critical patent/TW202241887A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW110148094A 2020-12-23 2021-12-22 4-胺基-3-(4-苯氧基苯基)-1,3-二氫-2h-咪唑並[4,5-c]吡啶-2-酮之衍生物及其鹽類 TW202241887A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063130010P 2020-12-23 2020-12-23
US63/130,010 2020-12-23
US202163245288P 2021-09-17 2021-09-17
US63/245,288 2021-09-17

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Publication Number Publication Date
TW202241887A true TW202241887A (zh) 2022-11-01

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Country Status (12)

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US (1) US12624030B2 (enExample)
EP (1) EP4267572A1 (enExample)
JP (1) JP2024501247A (enExample)
KR (1) KR20230124663A (enExample)
CN (1) CN116710452B (enExample)
AU (1) AU2021409575B2 (enExample)
CA (1) CA3206176A1 (enExample)
CO (1) CO2023009491A2 (enExample)
IL (1) IL303834A (enExample)
MX (1) MX2023007641A (enExample)
TW (1) TW202241887A (enExample)
WO (1) WO2022140511A1 (enExample)

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Publication number Publication date
CN116710452A (zh) 2023-09-05
MX2023007641A (es) 2023-07-07
AU2021409575B2 (en) 2026-06-04
AU2021409575A1 (en) 2023-08-10
US20240051955A1 (en) 2024-02-15
KR20230124663A (ko) 2023-08-25
US12624030B2 (en) 2026-05-12
EP4267572A1 (en) 2023-11-01
CN116710452B (zh) 2026-06-05
IL303834A (en) 2023-08-01
CO2023009491A2 (es) 2023-07-31
WO2022140511A1 (en) 2022-06-30
JP2024501247A (ja) 2024-01-11
CA3206176A1 (en) 2022-06-30

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