TW202228688A - 用於神經退化性疾病之症狀緩解或治療之貼附劑 - Google Patents

用於神經退化性疾病之症狀緩解或治療之貼附劑 Download PDF

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Publication number
TW202228688A
TW202228688A TW110132068A TW110132068A TW202228688A TW 202228688 A TW202228688 A TW 202228688A TW 110132068 A TW110132068 A TW 110132068A TW 110132068 A TW110132068 A TW 110132068A TW 202228688 A TW202228688 A TW 202228688A
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TW
Taiwan
Prior art keywords
scopolamine
patch
administration
hours
patch according
Prior art date
Application number
TW110132068A
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English (en)
Chinese (zh)
Inventor
小川孝行
西村健太
上野洋明
谷悠平
荻野美恵子
佐藤公紀
廿日岩久典
三好勝則
井上貴博
Original Assignee
日商耐貝醫藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 日商耐貝醫藥股份有限公司 filed Critical 日商耐貝醫藥股份有限公司
Publication of TW202228688A publication Critical patent/TW202228688A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW110132068A 2020-08-31 2021-08-30 用於神經退化性疾病之症狀緩解或治療之貼附劑 TW202228688A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020-145562 2020-08-31
JP2020145562 2020-08-31

Publications (1)

Publication Number Publication Date
TW202228688A true TW202228688A (zh) 2022-08-01

Family

ID=80353475

Family Applications (1)

Application Number Title Priority Date Filing Date
TW110132068A TW202228688A (zh) 2020-08-31 2021-08-30 用於神經退化性疾病之症狀緩解或治療之貼附劑

Country Status (8)

Country Link
US (1) US20230293510A1 (cg-RX-API-DMAC7.html)
EP (1) EP4205744A4 (cg-RX-API-DMAC7.html)
JP (1) JP7716111B2 (cg-RX-API-DMAC7.html)
CN (1) CN115989025A (cg-RX-API-DMAC7.html)
AU (1) AU2021331298A1 (cg-RX-API-DMAC7.html)
CA (1) CA3193154A1 (cg-RX-API-DMAC7.html)
TW (1) TW202228688A (cg-RX-API-DMAC7.html)
WO (1) WO2022045335A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114848613A (zh) * 2022-05-09 2022-08-05 山东中医药大学 一种东莨菪碱可溶性微针贴片及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7150881B2 (en) * 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
DE10301851A1 (de) * 2003-01-17 2004-07-29 Lts Lohmann Therapie-Systeme Ag Verfahren zur medikamentösen Prophylaxe gegen Vergiftungen durch Cholinesterase-Hemmer, sowie hierfür geeignete Wirkstoffe und Arzneimittel
US20070010550A1 (en) * 2005-07-08 2007-01-11 The Board Of Regents Of The University Of Texas Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia
US20080090808A1 (en) * 2006-10-17 2008-04-17 Franklin Volvovitz Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction
CN1994307B (zh) 2006-12-12 2010-05-12 中国人民解放军第二军医大学 一种预防有机磷酸酯类化合物中毒的复方经皮给药制剂
BRPI0913214B1 (pt) * 2008-05-30 2022-05-17 Mylan Laboratories Inc Dispositivo de fornecimento de drogas transdérmico e método de fabricação do mesmo
BR112019023393A2 (pt) * 2017-06-26 2020-06-16 Lts Lohmann Therapie-Systeme Ag Sistema terapêutico transdérmico contendo escopolamina e polímero híbrido de acrílico e silicone
WO2020189323A1 (ja) * 2019-03-19 2020-09-24 ノーベルファーマ株式会社 薬物の生体への吸収性に優れ、且つ、化学的安定性にも優れる医薬組成物

Also Published As

Publication number Publication date
CN115989025A (zh) 2023-04-18
US20230293510A1 (en) 2023-09-21
EP4205744A4 (en) 2024-09-11
EP4205744A1 (en) 2023-07-05
WO2022045335A1 (ja) 2022-03-03
JP7716111B2 (ja) 2025-07-31
AU2021331298A1 (en) 2023-03-23
JPWO2022045335A1 (cg-RX-API-DMAC7.html) 2022-03-03
CA3193154A1 (en) 2022-03-03

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