TW202114718A - 經加工的微生物胞外囊泡 - Google Patents

經加工的微生物胞外囊泡 Download PDF

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Publication number
TW202114718A
TW202114718A TW109119717A TW109119717A TW202114718A TW 202114718 A TW202114718 A TW 202114718A TW 109119717 A TW109119717 A TW 109119717A TW 109119717 A TW109119717 A TW 109119717A TW 202114718 A TW202114718 A TW 202114718A
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Taiwan
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pharmaceutical composition
pmev
bacteria
mev
cancer
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TW109119717A
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English (en)
Chinese (zh)
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馬克 柏德默
邦多納 波西
蘇菲亞 Ｍ Ｒ 卡爾頓
泰勒 Ａ 柯麥克
克里斯多夫 Ｊ Ｈ 大衛特
安德森 路易斯 弗朗西斯科
布萊恩 古德曼
安德烈 義塔諾
霍莉 波尼奇特拉
艾琳 Ｂ 特洛伊
切爾納克 法比安 Ｂ 羅曼諾
瑪麗亞 席偌瓦
艾利希亞 巴魯克
尼哈爾 歐肯
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美商艾弗洛生物科技股份有限公司
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Publication of TW202114718A publication Critical patent/TW202114718A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW109119717A 2019-06-11 2020-06-11 經加工的微生物胞外囊泡 TW202114718A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962860049P 2019-06-11 2019-06-11
US201962860029P 2019-06-11 2019-06-11
US62/860,049 2019-06-11
US62/860,029 2019-06-11
US202062979545P 2020-02-21 2020-02-21
US62/979,545 2020-02-21
US202062991767P 2020-03-19 2020-03-19
US62/991,767 2020-03-19

Publications (1)

Publication Number Publication Date
TW202114718A true TW202114718A (zh) 2021-04-16

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Family Applications (2)

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TW109119717A TW202114718A (zh) 2019-06-11 2020-06-11 經加工的微生物胞外囊泡
TW109119718A TW202128198A (zh) 2019-06-11 2020-06-11 分泌型微生物胞外囊泡

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TW109119718A TW202128198A (zh) 2019-06-11 2020-06-11 分泌型微生物胞外囊泡

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US (2) US20220249579A1 (es)
EP (2) EP3982987A1 (es)
JP (2) JP2022538765A (es)
KR (2) KR20220020893A (es)
CN (2) CN114096262A (es)
AU (2) AU2020291434A1 (es)
BR (2) BR112021024830A2 (es)
CA (2) CA3143036A1 (es)
CO (2) CO2022000041A2 (es)
MX (2) MX2021015429A (es)
TW (2) TW202114718A (es)
WO (2) WO2020252144A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019217526A1 (en) * 2018-02-06 2020-08-13 Evelo Biosciences, Inc. Compositions and methods for treating cancer and immune disorders using Veillonella bacteria
KR102286042B1 (ko) * 2019-01-09 2021-08-03 주식회사 엠디헬스케어 데이노코커스 속 세균 유래 나노소포 및 이의 용도
JP2023529199A (ja) * 2020-06-11 2023-07-07 エヴェロ バイオサイエンシズ，インコーポレーテッド ハリーフリンティア・アセティスポラ（Ｈａｒｒｙｆｌｉｎｔｉａ ａｃｅｔｉｓｐｏｒａ）を用いて疾患及び障害を治療するための組成物及び方法
TW202216178A (zh) * 2020-06-11 2022-05-01 美商艾弗洛生物科技股份有限公司 使用巨型球菌屬物種治療疾病及障礙之組成物及方法
EP4185307A1 (en) * 2020-07-21 2023-05-31 Evelo Biosciences, Inc. Veillonella parvula strain as an oral therapy for neuroinflammatory diseases
WO2022061119A1 (en) * 2020-09-21 2022-03-24 Evelo Biosciences, Inc. Compositions and methods for modulating immune responses with prevotella histicola
JP2024505207A (ja) * 2021-01-26 2024-02-05 エヴェロ バイオサイエンシズ，インコーポレーテッド プレボテラ（Ｐｒｅｖｏｔｅｌｌａ）細胞外小胞調製物
WO2022178209A1 (en) * 2021-02-19 2022-08-25 Evelo Biosciences, Inc. Compositions and methods for treating metabolic diseases and disorders using christensenellaceae bacteria
WO2022221183A1 (en) * 2021-04-12 2022-10-20 Evelo Biosciences, Inc. Fournierella extracellular vesicle preparations
WO2022251166A2 (en) * 2021-05-25 2022-12-01 Evelo Biosciences, Inc. Bacterial compositions comprising soy hemoglobin
WO2023114300A1 (en) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Fournierella massiliensis bacteria extracellular vesicle preparations
WO2023114296A2 (en) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Extracellular vesicle preparations
WO2023146843A1 (en) * 2022-01-25 2023-08-03 Evelo Biosciences, Inc. Extracellular vesicle compositions and methods of use
WO2023239728A1 (en) * 2022-06-07 2023-12-14 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles
CN118006515B (zh) * 2024-04-08 2024-06-18 中国农业大学 一株乳酸乳球菌及其在制备治疗牛乳腺炎的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101858840B1 (ko) * 2016-01-15 2018-05-16 단국대학교 천안캠퍼스 산학협력단 집먼지진드기 유래 알레르겐에 의한 과민반응 면역조절제
BR112019028301A2 (pt) * 2017-07-05 2020-07-14 Evelo Biosciences, Inc. composições e métodos para tratar câncer com o uso de bifidobacterium animalis ssp. lactis
TW201920648A (zh) * 2017-08-29 2019-06-01 美商艾弗洛生物科技股份有限公司 使用布勞特氏(blautia)菌株治療癌症
EP3679057A1 (en) * 2017-09-08 2020-07-15 Evelo Biosciences, Inc. Extracellular vesicles from prevotella
KR20200053531A (ko) * 2017-09-08 2020-05-18 에벨로 바이오사이언시즈, 인크. 박테리아 세포외 소포
JP2021502964A (ja) * 2017-11-14 2021-02-04 エヴェロ バイオサイエンシズ，インコーポレーテッド ブラウティア（Ｂｌａｕｔｉａ）株を使用して疾患を処置するための組成物及び方法
KR20200090189A (ko) * 2017-11-15 2020-07-28 에벨로 바이오사이언시즈, 인크. 면역조절 락토코쿠스 박테리아 균주를 사용하여 면역 장애를 치료하기 위한 조성물 및 방법
CN109580960A (zh) * 2019-01-14 2019-04-05 周明 细胞外囊泡的分离方法、以及检测细胞外囊泡表面标志物的方法和试剂盒

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Publication number Publication date
US20220249579A1 (en) 2022-08-11
BR112021024754A2 (pt) 2022-04-19
WO2020252149A1 (en) 2020-12-17
TW202128198A (zh) 2021-08-01
MX2021015429A (es) 2022-01-24
CN114096262A (zh) 2022-02-25
CO2022000041A2 (es) 2022-01-17
CN114650831A (zh) 2022-06-21
EP3982986A1 (en) 2022-04-20
WO2020252144A1 (en) 2020-12-17
BR112021024830A2 (pt) 2022-04-12
KR20220020894A (ko) 2022-02-21
CA3143025A1 (en) 2020-12-17
AU2020291003A1 (en) 2022-01-06
KR20220020893A (ko) 2022-02-21
EP3982987A1 (en) 2022-04-20
CA3143036A1 (en) 2020-12-17
JP2022538765A (ja) 2022-09-06
MX2021015427A (es) 2022-01-24
US20220296654A1 (en) 2022-09-22
AU2020291434A1 (en) 2022-01-06
JP2022537684A (ja) 2022-08-29
CO2022000040A2 (es) 2022-01-17

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